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Supplemental Table 1 Characteristics of the cohort with sepsis stratified by nutrition status (n=1,184)

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Supplemental Table 1

Characteristics of the cohort with sepsis stratified by nutrition status (n=1,184)

Malnutrition Absent

Nonspecific Malnutrition

Protein-Energy Malnutrition

P-value

Explicit Sepsis-no. 253 746 185

Pneumonia-no.(%) 139 (55.0) 365 (48.9) 97 (52.4) 0.23

Urinary Tract Infection-no.(%) 46 (18.2) 135 (18.1) 24 (13.0) 0.24

Cellulitis-no.(%) 30 (11.9) 74 (9.9) 13 (7.0) 0.25

Peritonitis-no.(%) 12 (4.7) 62 (8.3) 7 (3.8) 0.03

Device Infection-no.(%) 13 (5.1) 52 (7.0) 13 (7.0) 0.58 Colitis-no.(%) 10 (4.0) 40 (5.4) 14 (7.6) 0.25

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Supplemental Table 2

Characteristics of Propensity Score Matched patients (n= 4,104)

No Malnutrition Malnutrition P-value

N 2052 2052

Age-mean(SD) 63.6 (16.7) 62.9 (16.4) 0.17**

Male Gender-no.(%) 1181 (57.6) 1196 (58.3) 0.64

Non White Race-no.(%) 420 (20.5) 470 (22.9) 0.06

Surgical Patient Type-no.(%) 1066 (52.0) 1051 (51.2) 0.64

Explicit Sepsis-no.(%) 253 (12.3) 253 (12.3) 1.00

Vasopressores/Inotropes-no.(%) 936 (45.6) 938 (45.7) 0.95

Metastatic Disease-no.(%) 815 (39.7) 812 (39.6) 0.92

Deyo-Charlson Index-no.(%) 0.63

0-3 1721 (83.9) 1698 (82.8)

4-6 250 (12.2) 266 (13.0)

≥ 7 81 (4) 88 (4)

Acute organ failure-no.(%) 0.42

0 287 (14.0) 323 (15.7)

1 706 (34.4) 685 (33.4)

2 592 (28.9) 560 (27.3)

3 277 (13.5) 295 (14.38)

≥ 4 190 (9) 189 (9)

Nonspecific Malnutrition-no.(%) 0 (0) 1705 (83.09) <0.001

Protein-Energy Malnutrition-no.(%) 0 (0) 347 (16.91) <0.001

30-day Mortality-no.(%) 305 (14.9) 356 (17.4) 0.030

90-day Mortality-no.(%) 391 (19.1) 529 (25.8) <0.001

Note: P values determined by chi-square unless designated by (*) then P value determined by ANOVA.**

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