Supplementary file 2. Contingency tables for Chi-square to analyse categorical comparisons Table A.

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Supplementary file 2. Contingency tables for Chi-square to analyse categorical comparisons

Table A. Contingency table for comparisons between diagnosis and clinical presentation using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons. Adjusted p values < .05 are marked with (*).

Diagnosis

Clinical presentation

Total only cochlear

symptoms

only vestibular symptoms

both symptoms AVL +

SSNHL

Count 0 0 10 10

Expected count ,8 2,2 6,9 10,0

% within diagnosis 0,0% 0,0% 100,0% 100,0%

Adjusted residual -1,1 -1,9 2,4

p value ,2906 ,0565 ,0186

Adjusted p value 6,1027 1,1867 ,3897

IVN

Count 0 3 0 3

Expected count ,2 ,7 2,1 3,0

Adjusted residual -,5 3,3 -2,7

p value ,5941 ,0009 ,0071

Adjusted p value 12,4751 ,0187 (*) ,1494

CPA

Count 2 1 6 9

Adjusted residual 1,7 -,9 -,2

p value ,0882 ,3669 ,8446

Adjusted p value 1,8524 7,7054 17,7362

MD

Count 0 0 12 12

Expected count 1,0 2,7 8,3 12,0

p value ,2346 ,0320 ,0081

Adjusted p value 4,9271 ,6713 ,1701

BPPV

Count 0 5 0 5

Adjusted residual -,7 4,4 -3,6

p value ,4817 ,0000 ,0004

Adjusted p value 10,1163 ,0002 (*) ,0080 (*) Various

causes

Count 1 1 3 5

p value ,3077 ,8898 ,6308

Adjusted p value 6,4612 18,6868 13,2461

Undet

Count 1 1 3 5

p value ,3077 ,8898 ,6308

Adjusted p value 6,4612 18,6868 13,2461

Total

Count 4 11 34 49

Expected count 4,0 11,0 34,0 49,0

Abbreviations. AVL: acute vestibular loss. BPPV: benign paroxysmal positional vertigo. CPA: cerebellopontine angle.

IVN: inferior vestibular neuritis. MD: Meniere’s disease. SSNHL: sudden sensorineural hearing loss. Undet:

undetermined.

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Table B. Contingency table for comparisons between diagnosis and time from symptoms onset using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons. Adjusted p values

< .05 are marked with (*).

Diagnosis

time from onset

Total

< 1 week > 1 week,

< 1 month

> 1 month,

< 6 months > 6 months AVL +

SSNHL

Count 2 4 1 3 10

Expected count 1,4 1,2 1,4 5,9 10,0

% within diagnosis 20,0% 40,0% 10,0% 30,0% 100,0%

Adjusted residual ,6 3,0 -,4 -2,1

p value ,5627 ,0027 ,6642 ,0353

Adjusted p value 15,7557 ,0753 18,5976 ,9889

IVN

Count 3 0 0 0 3

Expected count ,4 ,4 ,4 1,8 3,0

Adjusted residual 4,4 -,7 -,7 -2,2

p value ,0000 ,5043 ,4655 ,0313

Adjusted p value ,0003 (*) 14,1200 13,0343 ,8778

CPA

Count 0 0 0 9 9

Expected count 1,3 1,1 1,3 5,3 9,0

Adjusted residual -1,4 -1,2 -1,4 2,8

p value ,1752 ,2149 ,1752 ,0058

Adjusted p value 4,9068 6,0161 4,9068 ,1631

MD

Count 0 1 1 10 12

Expected count 1,7 1,5 1,7 7,1 12,0

Adjusted residual -1,6 -,5 -,7 2,0

p value ,1036 ,6343 ,4977 ,0501

Adjusted p value 2,9019 17,7603 13,9356 1,4039

BPPV

Count 1 1 3 0 5

Adjusted residual ,4 ,6 3,1 -2,8

p value ,7000 ,5767 ,0021 ,0045

Adjusted p value 19,5997 16,1468 ,0574 ,1257 Various

causes

Count 1 0 0 4 5

Adjusted residual ,4 -,9 -1,0 1,0

p value ,7000 ,3781 ,3354 ,3176

Adjusted p value 19,5997 10,5861 9,3905 8,8927

Undet

Count 0 0 2 3 5

Adjusted residual -1,0 -,9 1,7 ,0

p value ,3354 ,3781 ,0829 ,9687

Adjusted p value 9,3905 10,5861 2,3216 27,1246 Total

Count 7 6 7 29 49

Expected count 7,0 6,0 7,0 29,0 49,0

undetermined.

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Table C. Contingency table for comparisons between diagnosis and nystagmus type using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons.

Diagnosis Nystagmus type

Total no

nystagmus

spontaneous nystagmus

positional nystagmus AVL +

SSNHL

Count 1 4 5 10

Adjusted residual -1,1 ,4 ,5

p value ,2903 ,6927 ,6089

Adjusted p value 6,0953 14,5477 12,7873

IVN

Count 0 3 0 3

Adjusted residual -1,0 2,5 -1,5

p value ,3362 ,0142 ,1216

Adjusted p value 7,0592 ,2978 2,5534

CPA

Count 3 1 5 9

Adjusted residual ,9 -1,6 ,9

p value ,3864 ,1000 ,3942

Adjusted p value 8,1144 2,0991 8,2783

MD

Count 2 6 4 12

Adjusted residual -,6 1,3 -,8

p value ,5806 ,1999 ,4430

Adjusted p value 12,1934 4,1975 9,3023

BPPV

Count 0 0 5 5

p value ,2042 ,0854 ,0064

Adjusted p value 4,2889 1,7944 ,1351

Various causes

Count 3 1 1 5

Adjusted residual 2,1 -,7 -1,1

p value ,0337 ,4663 ,2758

Adjusted p value ,7077 9,7933 5,7909

Undet

Count 2 2 1 5

Adjusted residual 1,0 ,3 -1,1

p value ,3209 ,7925 ,2758

Adjusted p value 6,7392 16,6428 5,7909

Total

Count 11 17 21 49

Expected count 11,0 17,0 21,0 49,0

undetermined.

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Table D. Contingency table for comparisons between diagnosis and nystagmus direction using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons.

Diagnosis

Nystagmus direction

Total no

nystagmus

ipsilesional nystagmus

contralesional nystagmus

vertical / torsional nystagmus

direction changing nystagmus AVL +

SSNHL

Count 1 0 0 7 2 10

Expected count 2,2 ,2 1,2 4,7 1,6 10,0

% within diagnosis 10,0% 0,0% 0,0% 70,0% 20,0% 100,0%

Adjusted residual -1,1 -,5 -1,3 1,6 ,4

p value ,2903 ,6089 ,1855 ,1014 ,7246

Adjusted p value 10,1589 21,3122 6,4919 3,5503 25,3617

IVN

Count 0 0 0 3 0 3

Expected count ,7 ,1 ,4 1,4 ,5 3,0

Adjusted residual -1,0 -,3 -,7 1,9 -,8

p value ,3362 ,7964 ,5043 ,0573 ,4297

Adjusted p value 11,7653 27,8736 17,6500 2,0072 15,0407

CPA

Count 3 0 1 3 2 9

Expected count 2,0 ,2 1,1 4,2 1,5 9,0

Adjusted residual ,9 -,5 -,1 -,9 ,5

p value ,3864 ,6318 ,9086 ,3654 ,5964

Adjusted p value 13,5240 22,1114 31,7999 12,7875 20,8726

MD

Count 2 1 3 3 3 12

Expected count 2,7 ,2 1,5 5,6 2,0 12,0

Adjusted residual -,6 1,8 1,6 -1,8 ,9

p value ,5806 ,0760 ,1209 ,0797 ,3495

Adjusted p value 20,3223 2,6614 4,2302 2,7894 12,2337

BPPV

Count 0 0 0 5 0 5

Expected count 1,1 ,1 ,6 2,3 ,8 5,0

Adjusted residual -1,3 -,3 -,9 2,5 -1,0

p value ,2042 ,7334 ,3781 ,0121 ,2973

Adjusted p value 7,1482 25,6693 13,2326 ,4239 10,4039

Various causes

Count 3 0 0 2 0 5

Expected count 1,1 ,1 ,6 2,3 ,8 5,0

Adjusted residual 2,1 -,3 -,9 -,3 -1,0

p value ,0337 ,7334 ,3781 ,7428 ,2973

Adjusted p value 1,1794 25,6693 13,2326 25,9997 10,4039

Undet

Count 2 0 2 0 1 5

Expected count 1,1 ,1 ,6 2,3 ,8 5,0

Adjusted residual 1,0 -,3 2,0 -2,2 ,2

p value ,3209 ,7334 ,0457 ,0265 ,8146

Adjusted p value 11,2320 25,6693 1,6003 ,9261 28,5102

Total Count 11 1 6 23 8 49

Expected count 11,0 1,0 6,0 23,0 8,0 49,0

undetermined.

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Table E. Contingency table for comparisons between diagnosis and VIN direction using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons.

Diagnosis

VIN direction

Total no

nystagmus

ipsilesional nystagmus

contralesional nystagmus

vertical / torsional nystagmus AVL +

SSNHL

Count 4 0 5 1 10

Expected count 3,9 1,0 4,3 ,8 10,0

Adjusted residual ,1 -1,2 ,5 ,2

p value ,9290 ,2321 ,6089 ,8121

Adjusted p value 26,0125 6,4997 17,0497 22,7375

IVN

Count 0 1 1 1 3

Expected count 1,2 ,3 1,3 ,2 3,0

Adjusted residual -1,4 1,4 -,3 1,6

p value ,1548 ,1720 ,7308 ,1003

Adjusted p value 4,3355 4,8150 20,4630 2,8088

CPA

Count 3 1 4 1 9

Adjusted residual -,4 ,1 ,1 ,4

p value ,7107 ,9207 ,9152 ,7207

Adjusted p value 19,9006 25,7809 25,6252 20,1805

MD

Count 3 1 8 0 12

Expected count 4,7 1,2 5,1 1,0 12,0

Adjusted residual -1,1 -,2 1,9 -1,2

p value ,2597 ,8054 ,0551 ,2346

Adjusted p value 7,2719 22,5511 1,5432 6,5694

BPPV

Count 4 0 0 1 5

Adjusted residual 2,0 -,8 -2,0 1,0

p value ,0459 ,4263 ,0410 ,3077

Adjusted p value 1,2846 11,9378 1,1479 8,6149

Various causes

Count 4 0 1 0 5

Adjusted residual 2,0 -,8 -1,1 -,7

p value ,0459 ,4263 ,2758 ,4817

Adjusted p value 1,2846 11,9378 7,7212 13,4884

Undet

Count 1 2 2 0 5

Adjusted residual -,9 2,3 -,1 -,7

p value ,3632 ,0202 ,8916 ,4817

Adjusted p value 10,1694 ,5654 24,9657 13,4884

Total Count 19 5 21 4 49

Expected count 19,0 5,0 21,0 4,0 49,0

undetermined. VIN: vibration-induced nystagmus.

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Table F. Contingency table for comparisons between diagnosis and degree of hearing loss using the Chi-square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons. Adjusted p values

< .05 are marked with (*).

Diagnosis

Degree of hearing loss

Total normal slight mild moderate moderate to

severe severe profound

AVL + SSNHL

Count 0 0 0 0 4 1 5 10

Expected count 1,8 ,8 1,6 1,4 2,4 ,6 1,2 10,0

% within diagnosis 0,0% 0,0% 0,0% 0,0% 40,0% 10,0% 50,0% 100,0%

Adjusted residual -1,7 -1,1 -1,6 -1,4 1,3 ,6 4,1

p value ,0927 ,2906 ,1174 ,1479 ,2011 ,5664 ,0000

Adjusted p value 4,5421 14,2397 5,7531 7,2460 9,8532 27,7557 ,0022 (*)

IVN

Count 2 1 0 0 0 0 0 3

Expected count ,6 ,2 ,5 ,4 ,7 ,2 ,4 3,0

Adjusted residual 2,2 1,6 -,8 -,7 -1,0 -,5 -,7

p value ,0258 ,1003 ,4297 ,4655 ,3087 ,6480 ,5043

Adjusted p value 1,2623 4,9155 21,0570 22,8101 15,1240 31,7527 24,7100

CPA

Count 1 0 1 4 2 1 0 9

Expected count 1,7 ,7 1,5 1,3 2,2 ,6 1,1 9,0

Adjusted residual -,6 -1,0 -,5 2,9 -,2 ,7 -1,2

p value ,5338 ,3222 ,6394 ,0042 ,8610 ,4896 ,2149

Adjusted p value 26,1560 15,7877 31,3309 ,2065 42,1895 23,9911 10,5282

MD

Count 0 1 4 1 4 1 1 12

Expected count 2,2 1,0 2,0 1,7 2,9 ,7 1,5 12,0

Adjusted residual -1,9 ,0 1,8 -,7 ,8 ,4 -,5

p value ,0586 ,9802 ,0666 ,4977 ,4123 ,7131 ,6343

Adjusted p value 2,8729 48,0320 3,2639 24,3874 20,2036 34,9443 31,0804

BPPV

Count 3 1 0 0 1 0 0 5

Expected count ,9 ,4 ,8 ,7 1,2 ,3 ,6 5,0

Adjusted residual 2,5 1,0 -1,0 -1,0 -,2 -,6 -,9

p value ,0112 ,3077 ,2973 ,3354 ,8054 ,5468 ,3781

Adjusted p value ,5477 15,0761 14,5654 16,4334 39,4644 26,7915 18,5256 Various

causes

Count 2 0 1 1 1 0 0 5

Expected count ,9 ,4 ,8 ,7 1,2 ,3 ,6 5,0

Adjusted residual 1,3 -,7 ,2 ,4 -,2 -,6 -,9

p value ,1874 ,4817 ,8146 ,7000 ,8054 ,5468 ,3781

Adjusted p value 9,1829 23,6047 39,9142 34,2994 39,4644 26,7915 18,5256

Undet

Count 1 1 2 1 0 0 0 5

Expected count ,9 ,4 ,8 ,7 1,2 ,3 ,6 5,0

Adjusted residual ,1 1,0 1,5 ,4 -1,3 -,6 -,9

p value ,9207 ,3077 ,1307 ,7000 ,1790 ,5468 ,3781

Adjusted p value 45,1166 15,0761 6,4037 34,2994 8,7711 26,7915 18,5256 Total

Count 9 4 8 7 12 3 6 49

Expected count 9,0 4,0 8,0 7,0 12,0 3,0 6,0 49,0

undetermined.

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Table G. Contingency table for comparisons between diagnosis and configuration of hearing loss using the Chi- square method and adjusting p value with the Bonferroni correction to compensate for multiple comparisons. Adjusted p values < .05 are marked with (*).

Diagnosis Hearing loss configuration

Total normal high-frequency low-frequency sloping flat

AVL + SSNHL

Count 0 0 0 1 9 10

Expected count 1,8 1,2 ,8 2,9 3,3 10,0

Adjusted residual -1,7 -1,3 -1,1 -1,5 4,3

p value ,0927 ,1855 ,2906 ,1451 ,0000

Adjusted p value 3,2444 6,4919 10,1712 5,0775 ,0005 (*)

IVN

Count 2 1 0 0 0 3

Expected count ,6 ,4 ,2 ,9 1,0 3,0

Adjusted residual 2,2 1,2 -,5 -1,1 -1,2

p value ,0258 ,2501 ,5941 ,2582 ,2132

Adjusted p value ,9016 8,7546 20,7919 9,0378 7,4628

CPA

Count 1 1 0 6 1 9

Expected count 1,7 1,1 ,7 2,6 2,9 9,0

Adjusted residual -,6 -,1 -1,0 2,8 -1,5

p value ,5338 ,9086 ,3222 ,0051 ,1272

Adjusted p value 18,6829 31,7999 11,2770 ,1789 4,4515

MD

Count 0 0 4 2 6 12

Expected count 2,2 1,5 1,0 3,4 3,9 12,0

Adjusted residual -1,9 -1,5 3,7 -1,1 1,5

p value ,0586 ,1365 ,0002 ,2935 ,1403

Adjusted p value 2,0521 4,7760 ,0087 (*) 10,2717 4,9107

BPPV

Count 3 1 0 1 0 5

Expected count ,9 ,6 ,4 1,4 1,6 5,0

Adjusted residual 2,5 ,6 -,7 -,4 -1,6

p value ,0112 ,5767 ,4817 ,6544 ,1004

Adjusted p value ,3912 20,1835 16,8605 22,9024 3,5128

Various causes

Count 2 2 0 1 0 5

Expected count ,9 ,6 ,4 1,4 1,6 5,0

Adjusted residual 1,3 2,0 -,7 -,4 -1,6

p value ,1874 ,0457 ,4817 ,6544 ,1004

Adjusted p value 6,5592 1,6003 16,8605 22,9024 3,5128

Undet

Count 1 1 0 3 0 5

Expected count ,9 ,6 ,4 1,4 1,6 5,0

Adjusted residual ,1 ,6 -,7 1,6 -1,6

p value ,9207 ,5767 ,4817 ,1007 ,1004

Adjusted p value 32,2261 20,1835 16,8605 3,5232 3,5128

Total

Count 9 6 4 14 16 49

Expected count 9,0 6,0 4,0 14,0 16,0 49,0

undetermined.