e-Table 1 (for online supplementary material): Demographic, anthropometric parameters, sleep and hemodialysis characteristics, measurements performed before sleep and their overnight changes in fluid removal group and no-removal group
Fluid Removal Group No-Removal Group
Pre-HD Polysomnography
Post-HD Polysomnography
p Pre-HD
Polysomnography
Post-HD Polysomnography
p Neck circumference (cm)
[in the evening]
42.0 (3.0) 41.3 (3.1) 0.008 41.4 (3.0) 40.7 (2.9) 0.108
pH 7.34 (0.08) 7.45 (0.07) 0.003 7.36 (0.02) 7.45 (0.04) 0.022
Bicarbonates (mEq/l) 22.1 (2.3) 27.2 (1.8) <0.001 22.5 (1.9) 26.5 (3.7) 0.012
BUN (mg/dl) 53.2 (18.5) 14.3 (4.5) <0.001 57.7 (14.3) 13.2 (4.5) 0.004
Fluid overload volume (L) 2.59 (1.35) 1.16 (1.09) <0.001 0.50 (0.90) 0.80 (1.29) 0.329 Leg fluid volume (L)
[in the evening]
10.59 (2.11) 9.63 (1.91) <0.001 10.90 (1.51) 10.49 (1.76) 0.149 Overnight rostral fluid shift (L) 1.30 (0.44) 0.72 (0.43) <0.001 1.20 (0.33) 0.94 (0.15) 0.159
Total sleep time (min) 353 (67) 374 (80) 0.414 333 (89) 342 (125) 0.668
Sleep efficiency (%) 78.7 (14.5) 82.4 (8.3) 0.484 72.2 (21.9) 72.3 (24.9) 0.984
Light sleep (St 1-2) (%) 72.8 (13.9) 61.0 (12.8) 0.059 60.2 (12.8) 61.7 (11.7) 0.869
Deep sleep (St 3) (%) 6.9 (7.1) 9.8 (6.8) 0.054 9.1 (13.6) 6.8 (5.6) 0.567
REM sleep (%) 14.5 (7.0) 20.0 (9.9) 0.093 17.9 (12.6) 21.6 (11.8) 0.321
Supine sleep time (%) 43.2 (28.2) 30.4 (18.9) 0.226 60.7 (24.3) 48.1 (28.1) 0.162
OAHI (no./h) 52.3 (20.7) 42.2 (19.2) 0.008 33.9 (21.4) 42.1 (19.1) 0.318
AHI (no./h) 61.6 (21.7) 53.2 (21.4) 0.050 43.0 (21.1) 55.0 (26.8) 0.312
Central apneas (no./h) 6.1 (9.1) 7.7 (10.9) 0.302 3.3 (3.4) 5.8 (7.6) 0.422
AHI in supine position (no./h) 76.7 (23.1) 64.4 (23.5) 0.037 56.5 (34.4) 70.4 (35.4) 0.174 AHI non supine position (no./h) 52.5 (24.2) 51.3 (27.4) 0.813 31.0 (13.2) 47.9 (23.5) 0.238 AHI in REM sleep (no./h) 48.1 (16.9) 42.3 (17.6) 0.174 21.6 (21.3) 34.3 (25.4) 0.103 AHI in NREM sleep (no./h) 62.7 (24.3) 54.8 (25.1) 0.076 44.3 (24.7) 57.3 (34.4) 0.360
Mean SaO2 (%) 92.8 (1.7) 92.9 (2.2) 0.643 93.5 (1.1) 93.0 (1.1) 0.126
ODI (no./h) 55.9 (23.3) 50.4 (21.7) 0.180 40.0 (18.5) 55.3 (25.2) 0.196
Values are expressed as mean (SD). p represents the difference between pre- and post-hemodialysis values, by paired Student’s t-test.
HD = hemodialysis; OAHI = index of obstructive apneas and hypopneas per hour of sleep; AHI = index of apneas and hypopneas per hour of sleep; REM = rapid eye movement sleep; NREM = non-rapid eye movement sleep; SaO2 = oxygen saturation; ODI = oxygen desaturation index (index of desaturations per hour of sleep); BUN = blood urea nitrogen; Delta = change from pre-hemodialysis to post-hemodialysis
