Supplementary Table 1. Published Genetic Associations for Sjögren’s syndrome and SLE.
Study Population Top snp in signal Chr Pos Genes in the region OR PMID Interferome IFN pathway
Langefeld [1] European Americans rs11590283 1 1245368 CPSF3L 0.86 28714469 NA NA
Langefeld European Americans rs12142199 1 1249187 CPSF3L 0.87 28714469 NA NA
Li [2] Chinese rs4649203 1 24519920 IL28RA 1.16 24070858 NA NA
Langefeld European Americans rs6662618 1 92935411 GFI1, EVI5 1.18 28714469 NA NA
Langefeld European Americans rs12738833 1 93119118 GFI1, EVI5 1.12 28714469 NA NA
Langefeld European Americans rs11578098 1 93119410 GFI1, EVI5 1.13 28714469 NA NA
Gateva [3] American and Swedish rs2476601 1 114377568 PTPN22, BCL2L15, DCLRE1B, MAGI3
1.35 19838195 Down Production
Wen [4] Chinese rs1335532 1 117100957 CD58 1.12 29233832 Up NA
Langefeld African American rs835573 1 120464165 NOTCH2 1.1 28714469 NA NA
Langefeld European American rs835573 1 120464165 NOTCH2 1.15 28714469 NA NA
Langefeld Hispanic American rs835573 1 120464165 NOTCH2 1.12 28714469 NA NA
Langefeld European Americans rs41264285 1 155033918 ADAM15, EFNA1 1.14 28714469 NA NA Langefeld European Americans rs45444697 1 155034632 ADAM15, EFNA1 1.14 28714469 NA NA Langefeld European Americans rs4971066 1 155105882 ADAM15, EFNA1 0.87 28714469 NA NA
Bentham [5] European rs1801274 1 161479745 FCGR2A, FCGR2B 1.16 26502338 NA NA
Langefeld African American rs12068671 1 172681031 FASLG 0.96 28714469 Up NA
Langefeld European American rs12068671 1 172681031 FASLG 0.88 28714469 Up NA
Langefeld Hispanic American rs12068671 1 172681031 FASLG 0.79 28714469 Up NA
Han [6] Asian and European rs1234315 1 173178463 TNFSF4 1.37 19838193 NA NA
Gateva Asian, European American, African American, Hispanic American, European
rs2205960 1 173191475 TNFSF4 1.22 19838195 NA NA
Bentham European rs704840 1 173226195 TNFSF4 1.22 26502338 NA NA
Sheng [7] Chinese rs1418190 1 173361979 TNFSF4 0.81 25890262 NA NA
Sheng Chinese rs4916219 1 173373183 TNFSF4 0.8 25890262 NA NA
Kim-Howard [8]
European-American rs17849502 1 183532580 NCF2 2.57 24163247 NA NA
Kim-Howard African American rs35937854 1 183536089 NCF2 2.34 24163247 NA NA
Cunninghame
Graham [9] UK, American and Swedish rs10911363 1 183549757 NCF2 1.23 22046141 NA NA
Armstrong [10]
European rs10911628 1 184649503 EDEM3 1.954 24871463 NA NA
Morris [11] Chinese and European rs34889541 1 198594769 CD45 0.81 27399966 NA NA
Morris Chinese and European rs2297550 1 206643772 IKBKE 1.16 27399966 NA NA
Gateva American and European rs3024505 1 206939904 FCAMR, IL10, IL24 1.19 19838195 Up NA
Bentham European rs9782955 1 236039877 LYST 1.16 26502338 Down NA
Langefeld African American rs7579944 2 30445026 LBH1 0.86 28714469 NA NA
Langefeld European American rs7579944 2 30445026 LBH1 0.92 28714469 NA NA
Langefeld Hispanic American rs7579944 2 30445026 LBH1 0.89 28714469 NA NA
Morris Chinese and European rs7579944 2 30445026 LBH 0.9 27399966 NA NA
Morris Chinese and European rs17321999 2 30479857 LBH 0.83 27399966 NA NA
Han Chinese rs13385731 2 33701890 RASGRP3 0.7 19838193 Up NA
Langefeld European Americans rs6756736r 2 43558743 THADA 1.22 28714469 NA NA
Langefeld European Americans rs6705304 2 43596746 THADA 0.86 28714469 NA NA
Langefeld European Americans rs62149377 2 60986576 PAPOLG 1.14 28714469 NA NA
Langefeld European Americans rs115291397 2 61060043 PAPOLG 0.61 28714469 NA NA
Langefeld European Americans rs2600669 2 61401296 PAPOLG 0.9 28714469 NA NA
Langefeld European Americans rs115268109 2 61833802 LOC100132037, FLJ13305 1.31 28714469 NA NA
Bentham European rs6740462 2 65667272 SPRED2 1.1 26502338 Down NA
Yang [12] Asian rs4852324 2 74202578 DGUOK, TET3 0.79 23273568 NA NA
Yang Asian rs6705628 2 74208362 DGUOK 0.75 23273568 NA NA
Langefeld European Americans rs11681718 2 103051144 IL18RAP 0.88 28714469 NA NA
Langefeld European Americans rs2460382 2 135014116 MGAT5 0.91 28714469 NA NA
Langefeld European Americans rs10496726 2 135045250 MGAT5 0.85 28714469 NA NA
Langefeld European Americans rs11887156 2 135066476 MGAT5 0.84 28714469 NA NA
Wen Chinese rs2322659 2 136555659 LCT 1.124 29233832 NA NA
Wen Chinese rs3754689 2 136590746 LCT 0.877 29233832 NA NA
Molineros [13] African American rs13023380 2 162846229 IFIH1 0.75 23441136 NA Production
Molineros European American rs13023380 2 162846229 IFIH1 0.84 23441136 NA Production
Bentham European rs2111485 2 163110536 IFIH1 1.15 26502338 Up Production
Molineros African American rs10930046 2 163137983 IFIH1 0.8 23441136 NA Production
Molineros European American rs10930046 2 163137983 IFIH1 1.21 23441136 NA Production
Lee [14] Korean rs3821236 2 191902758 STAT4 1.56 23740238 NA NA
Yang [15] Chinese rs7601754 2 191940451 STAT4 0.59 19225526 NA NA
Bentham European rs11889341 2 191943742 STAT4 1.73 26502338 Up NA
Bentham European rs6736175 2 191946322 STAT4 1.24 26502338 NA NA
Lee [16] European rs10931481 2 191954852 STAT4 1.312 23053960 NA NA
Langefeld European Americans rs2196171 2 198889807 PLCL1 0.89 28714469 NA NA
Langefeld European Americans rs6738825 2 198896895 PLCL1 0.9 28714469 NA NA
Bentham European rs3768792 2 213871709 IKZF2 1.24 26502338 NA NA
Vaughn [17] European Americans, African Americans, Asian Americans and Hispanic Americans
rs6445972 3 58321707 ABHD6, PXK, RPP14, PDHB
0.81 25620976 NA NA
SLEGEN [18] European rs6445975 3 58370177 PXK 1.25 18204446 NA NA
Bentham European rs9311676 3 58470351 ABHD6 PXK 1.17 26502338 Down NA
Langefeld Hispanic American rs73846279 3 89891345 EPHA3, PROS1 1.57 28714469 NA NA
Langefeld Hispanic American rs7653338 3 89938088 EPHA3, PROS1 1.58 28714469 NA NA
Langefeld European Americans rs1132200 3 119150836 TMEM39A1, TIMMDC1 0.83 28714469 NA NA Langefeld European Americans rs1131265 3 119222456 TMEM39A1, TIMMDC1 0.81 28714469 NA NA
Yang Asian rs6804441 3 119260944 CD80 0.79 23273568 Up NA
Zhang [19] Asian rs2222631 3 119272391 CD80 0.86 25862617 NA NA
Langefeld European Americans rs1534154 3 119311030 TMEM39A1, TIMMDC1 1.11 28714469 NA NA Bentham European rs564799 3 159728987 IL12A, IFT80, SMC4,
RP11-432B6.3
1.14 26502338 NA NA
Molineros [20] Asian and European rs10936599 3 169492101 MYNN 1.14 28108556 NA NA
Wen Chinese rs10936599 3 169492101 MYNN 1.126 29233832 NA NA
Wen Chinese rs6793295 3 169518455 LRRC34 1.138 29233832 NA NA
Morris Chinese and European rs6762714 3 188470238 LPP, TPRG1, AS1 1.16 27399966 Down NA
Langefeld European Americans rs3733345 4 954247 DGKQ 0.89 28714469 NA NA
Langefeld European Americans rs4690229 4 970724 DGKQ 1.13 28714469 NA NA
Okada [21] Japanese rs340630 4 87958395 AFF1 1.21 22291604 Up NA
Bentham European rs10028805 4 102737250 BANK1 1.2 26502338 NA NA
Chang [22] Chinese rs17266594 4 102750922 BANK1 0.61 19357697 NA NA
Hughes [23] European and African American
rs907715 4 123535053 IL21 1.16 21425124 NA NA
Sun [24] Asian rs7726159 5 1282319 TERT 1.21 26808113 NA NA
Langefeld African American rs461193 5 1368997 BC034612 1.08 28714469 NA NA
Langefeld European American rs461193 5 1368997 BC034612 1.13 28714469 NA NA
Langefeld Hispanic American rs461193 5 1368997 BC034612 1.19 28714469 NA NA
Bentham European and Asian rs7726414 5 133431834 TCF7, SKP1 1.45 26502338 Down NA
Gateva American and Swedish rs7708392 5 150457485 TNIP1 1.27 19838195 Down NA
Langefeld European Americans rs4921317 5 158538277 LOC285627 1.17 28714469 NA NA
Langefeld European Americans rs6869688 5 158883027 LOC285627 0.89 28714469 NA NA
Langefeld European Americans rs7720046 5 158884535 LOC285627 0.89 28714469 NA NA
Sun Asian rs2421184 5 159459931 IL12B 0.84 26808113 NA NA
Bentham Chinese and European, African American
rs2431697 5 159879978 PTTG1, MIR146A 1.26 26502338 NA NA
Langefeld African American rs2431697 5 159879978 PTTG1, MIR146A1 0.76 28714469 NA NA
Morris Chinese and European rs17603856 6 16630898 ATXN1 0.88 27399966 Down NA
Langefeld African American rs909788 6 16636461 ATXN1 1.06 28714469 NA NA
Langefeld European American rs909788 6 16636461 ATXN1 1.1 28714469 NA NA
Langefeld Hispanic American rs909788 6 16636461 ATXN1 1.17 28714469 NA NA
Langefeld European Americans rs10498722 6 25186512 LRRC16A 1.3 28714469 NA NA
Chen [25] European rs35789010 6 25514179 LRRC16A 28509669 NA NA
Langefeld European Americans rs35789010 6 25514179 LRRC16A 1.46 28714469 NA NA
Langefeld European Americans rs4712969 6 25764192 SLC17A4 1.42 28714469 NA NA
Chen European rs36014129 6 25884519 SLC17A4 28509669 NA NA
Langefeld European Americans rs36014129 6 25884519 SLC17A4 1.5 28714469 NA NA
Fernando [26] UK, Spanish and Filipino rs3906272 6 31262924 HLA-C, HLA-B 2.84 22233601 NA NA
Morris [27] European rs2246618 6 31478986 MICB 1.49 23084292 NA NA
SLEGEN European rs1269852 6 32080191 MSH5, SAPCD1, TNXB,
ATF6B
1.87 18204446 NA NA
Morris European rs8192591 6 32185796 NOTCH4 0.54 23084292 NA NA
Hom [28] European rs2187668 6 32605884 HLA-DQA1 NA 18204098 NA NA
SLEGEN European rs9275572 6 32678999 HLA 1.4 18204446 NA NA
Lee European rs2051549 6 32730086 HLA-DQA2 NA 23053960 NA NA
Oishi [29] Japanese rs3748079 6 33588147 ITPR3 1.88 18219441 Down NA
Langefeld African American rs34840245 6 34812701 UHRF1BP1, DEF6 1.21 28714469 NA NA
Langefeld European Americans rs71567468 6 34816070 DEF6, PPARD 1.29 28714469 NA NA
Zhang [30] Asian and European rs3734266 6 34823187 UHRF1BP1 NA 26202167 NA NA
Gateva American and Swedish rs11755393 6 34824636 UHRF1BP1 1.17 19838195 NA NA
Molineros Asian and European rs2762340 6 35052635 ANKS1A 0.87 28108556 NA NA
Langefeld Hispanic American rs9394274 6 35114911 TCP11, SCUBE3 1.34 28714469 NA NA
Langefeld African American rs1194 6 35263555 UHRF1BP1, DEF6 1.32 28714469 NA NA
Langefeld European Americans rs6920432 6 35298662 DEF6, PPARD 1.15 28714469 NA NA
Sun Asian rs10807150 6 35304497 DEF6 1.25 26808113 NA NA
Morris Chinese and European rs597325 6 91002494 BACH2 0.89 27399966 NA NA
Han Chinese rs548234 6 106568034 PRDM1, ATG5 1.25 19838193 Up NA
Gateva American and European rs6568431 6 106588806 PRDM1 1.2 19838195 NA NA
Langefeld African American rs11154801 6 135739355 AHI1 1.13 28714469 NA NA
Langefeld European American rs11154801 6 135739355 AHI1 1.11 28714469 NA NA
Langefeld Hispanic American rs11154801 6 135739355 AHI1 1.09 28714469 NA NA
Chen European rs2327832 6 137973068 OLIG3, LOC100130476 28509669 NA NA
Langefeld European Americans rs2327832 6 137973068 OLIG3, LOC100130476 1.22 28714469 NA NA Langefeld European Americans rs17779870 6 138156425 OLIG3, LOC100130476 0.85 28714469 NA NA
Langefeld European Americans rs5029939 6 138195723 TNFAIP3 1.81 28714469 NA Production
Langefeld European Americans rs2230926P 6 138196066 TNFAIP3 1.81 28714469 NA Production Langefeld European Americans rs77000060 6 138237989 TNFAIP3 1.89 28714469 Up Production
Bentham European rs6932056 6 138242437 TNFAIP3 1.83 26502338 NA Production
Langefeld Hispanic American rs12199481 6 159381492 RSPH3 0.78 28714469 NA NA
Langefeld Hispanic American rs2092540 6 159416444 RSPH3 0.73 28714469 NA NA
Langefeld African American rs7795074 7 26742154 SKAP2 0.88 28714469 Down NA
Langefeld European American rs7795074 7 26742154 SKAP2 0.93 28714469 Down NA
Langefeld Hispanic American rs7795074 7 26742154 SKAP2 0.84 28714469 Down NA
Gateva American and European rs849142 7 28185891 JAZF1 1.19 19838195 NA NA
Cunninghame UK, American and Swedish rs2366293 7 50227828 IKZF1 1.2 22046141 NA NA
Bentham Chinese and European rs4917014 7 50305863 IKZF1 1.18 26502338 NA NA
Morris Chinese and European rs73135369 7 73940978 GTF2IRD1, GTF2I 1.32 27399966 NA NA Langefeld European Americans rs73137125 7 74018950 GTF2IRD1, GTF2I 0.92 28714469 NA NA Langefeld European Americans rs73366469 7 74033600 GTF2IRD1, GTF2I 1.29 28714469 NA NA
Sun Asian and European rs73366469 7 74619286 GTF2IRD1, GTF2I 2.38 26808113 NA NA
Han Chinese rs1167796 7 75173180 HIP1 0.83 19838193 NA NA
Lessard [31] Asian rs6964720 7 75180344 HIP1 1.4 26663301 Down NA
Hu [32] Asian and European rs729302 7 128568960 TNPO3, IRF5 0.78 21834935 NA NA
Han Chinese and European rs4728142 7 128573967 IRF5 1.43 19838193 NA NA
Gateva American and Swedish rs2070197 7 128589000 IRF5 1.43 19838195 NA NA
SLEGEN European rs12537284 7 128717906 IRF5, TNPO3 1.61 18204446 Up Signaling
Langefeld European Americans rs2955587 8 8098079 FAM86B3P 1.15 28714469 NA NA
Langefeld European Americans rs2980512 8 8140901 FAM86B3P 1.15 28714469 NA NA
Langefeld European Americans rs1039917 8 8718850 MFHAS1 1.13 28714469 Up NA
Langefeld African American rs6601327 8 9395532 TNKS 1.1 28714469 Down NA
Langefeld European American rs6601327 8 9395532 TNKS 1.11 28714469 Down NA
Langefeld Hispanic American rs6601327 8 9395532 TNKS 1.06 28714469 Down NA
SLEGEN European rs6985109 8 10767748 XKR6 1.23 18204446 NA NA
SLEGEN European rs7836059 8 11272164 C8orf12 0.82 18204446 NA NA
Lee European rs12680762 8 11332026 FAM167A 1.335 23053960 NA NA
Han Chinese rs7812879 8 11340181 BLK, RP11-148O21.2,
RP11-148O21.4
0.69 19838193 NA NA
Gateva American and Swedish rs2736340 8 11343973 BLK 1.35 19838195 NA NA
Han Chinese rs2248932 8 11391650 BLK 0.76 19838193 NA NA
Langefeld African American rs1804182 8 42033519 PLAT 1.94 28714469 NA NA
SLEGEN European rs7829816 8 56849386 LYN 0.77 18204446 Up NA
Langefeld European Americans rs1966115 8 79556891 PKIA, ZC2HC1A 1.14 28714469 NA NA Langefeld European Americans rs12114284 8 79558441 PKIA, ZC2HC1A 1.11 28714469 NA NA Langefeld European Americans rs12156002 8 129190544 PVT1, BC009730 0.87 28714469 NA NA Langefeld European Americans rs6651252 8 129567181 PVT1, BC009730 0.85 28714469 NA NA
Morris Chinese and European rs1887428 9 4984530 JAK2 1.16 27399966 Up NA
Langefeld European Americans rs11788118 9 102337331 AK057451 0.88 28714469 NA NA
Langefeld European Americans rs10819689 9 102400263 AK057451 0.87 28714469 NA NA
Langefeld European Americans rs12722558 10 6070276 IL2RA 1.11 28714469 NA NA
Langefeld European Americans rs10905718 10 6114856 IL2RA 1.12 28714469 NA NA
Langefeld European Americans rs112123005 10 6472492 IL2RA 1.33 28714469 Up NA
Langefeld European Americans rs113304138 10 6564277 IL2RA 0.65 28714469 NA NA
Yang [33] Asian rs7097397 10 50025396 WDFY4 1.3 20169177 NA NA
Yang Asian and European rs877819 10 50042951 WDFY4 1.557 20169177 Down NA
Han Chinese rs1913517 10 50119054 LRRC18-WDFY4 1.24 19838193 NA NA
Bentham Asian and European rs4948496 10 63805617 ARID5B 1.14 26502338 NA NA
Alarcón-
Riguelme [34] Amerindian rs4917385 10 103243964 USMG5, miR1307 0.72 26606652 NA NA
Bentham European rs12802200 11 566936 IRF7, PHRF1, HRAS, TMEM80,RNH1, ANO9, RASSF7
1.23 26502338 Up Signaling
Gateva American and European rs4963128 11 589564 PHRF1 1.2 19838195 NA NA
Lessard [35] European, African American and Asian
rs2732552 11 35084592 CD44 0.81 21194677 Down NA
Molineros Asian and European rs1308020 11 65497558 CTSW, RNASEH2C, FIBP, MUS81
0.84 28108556 NA NA
Morris Chinese and European rs494003 11 65542298 RNASEH2C 1.14 27399966 NA NA
Sun Asian rs2009453 11 65632057 PCNXL3 0.84 26808113 NA NA
Wen Chinese rs10750836 11 68815523 TPCN2 1.091 29233832 NA NA
Bentham European rs3794060 11 71187679 NADSYN1, RP11-660L16.2, DHCR7
1.23 26502338 NA NA
Molineros Asian and European rs11235604 11 72533536 ATG16L2 0.78 28108556 Down NA
Lessard Asian rs11235667 11 72863697 FCHSD2,P2RY2 0.59 26663301 Down NA
Zhang [36] Asian rs11603023 11 118486067 PHLDB1 1.2 24001599 NA NA
Han Chinese rs4639966 11 118573519 1.29 19838193 Up NA
Zhang Asian rs10892301 11 118735476 CXCR5 0.85 24001599 NA NA
Han Asian rs6590330 11 128311059 ETS1,FLI1 1.37 19838193 Down NA
Bentham European rs7941765 11 128499000 ETS1 FLI1 1.14 26502338 NA NA
Yang Asian rs12822507 12 12773521 CREBL2 0.86 23273568 Down NA
Yang Asian rs10845606 12 12834894 GPR19 0.79 23273568 NA NA
Yang Asian rs34330 12 12870695 CDKN1B 0.84 23273568 NA NA
Demirci [37] European rs10506216 12 43130885 PRICKLE1 1.7 26316170 Up NA
Langefeld Hispanic American rs2041862 12 68461697 DYRK2, IFNG 0.66 28714469 Up NA
Langefeld Hispanic American rs17005500 12 79738884 SYT1 0.58 28714469 NA NA
Yang Asian rs4622329 12 102321935 DRAM1 0.84 23273568 Up NA
Bentham European rs10774625 12 111910219 SH2B3, ATXN2, HECTD4 1.13 26502338 NA NA
Langefeld African American rs17630235 12 112591686 TRAFD1, C12orf51 1.11 28714469 Up NA Langefeld European American rs17630235 12 112591686 TRAFD1, C12orf51 1.1 28714469 Up NA Langefeld Hispanic American rs17630235 12 112591686 TRAFD1, C12orf51 1.18 28714469 Up NA
Wen Chinese rs1051042 12 113357237 OAS1 0.89 29233832 Up Signaling
Bentham European rs1059312 12 129278864 SLC15A4 1.17 26502338 NA NA
Han Chinese rs10847697 12 129299385 SLC15A4 1.26 19838193 Down NA
Yang [38] Asian rs7329174 13 41558110 ELF1 1.26 21044949 Up NA
Li Chinese rs8016947 14 35832666 NFKBIA 0.83 24070858 Down NA
Bentham European rs4902562 14 68731458 RAD51B 1.14 26502338 NA NA
Chen Hispanic rs11845506 14 88383035 GALC 28509669 Down NA
Langefeld Hispanic American rs11845506 14 88383035 GALC 0.2 28714469 Down NA
Wen Chinese rs4465542 14 105407798 AHNAK2 0.824 29233832 NA NA
Sun Asian rs12900339 15 38635185 RASGRP1 1.18 26808113 Down NA
Armstrong European rs11073328 15 38764843 FAM98B 1.935 24871463 Down NA
Wen Chinese rs8035957 15 38838264 RASGRP1 0.874 29233832 NA NA
Manjarrez- Orduño [39]
European rs34933034 15 75079474 FAM219B, CSK, MPI, C15ORF39, ULK3, UBE2Q2
1.32 23042117 NA NA
Bentham European rs2289583 15 75311036 CSK 1.19 26502338 NA NA
Armstrong European rs8023715 15 97607681 SPATA8 1.812 24871463 NA NA
Chen Hispanic rs8054198 16 11038360 CLEC16A, CIITA, SOCS1 28509669 NA NA
Langefeld Hispanic American rs8054198 16 11038360 CLEC16A 0.36 28714469 NA NA
Bentham European rs9652601 16 11174365 CIITA SOCS1 1.21 26502338 NA NA
Langefeld Hispanic American rs12448240 16 11187218 CLEC16A 2.06 28714469 NA NA
Zhang [40] Chinese rs12599402 16 11189888 CLEC16A 0.81 20805369 NA NA
Langefeld Hispanic American rs12925552 16 11332805 CLEC16A 0.84 28714469 NA NA
Langefeld Hispanic American rs12925552 16 11332805 CLEC16A 0.84 28714469 NA NA
Sheng [41] Chinese rs16972959 16 23901376 PRKCB, PYCARD 0.81 21134959 Down NA
Han Chinese rs7197475 16 30642867 ITGAM, ITGAX 1.31 19838193 NA NA
Bentham European rs34572943 16 31272353 ITGAM 1.71 26502338 Up NA
Hom European rs11574637 16 31368874 ITGAM, ITGAX 1.3 18204098 NA NA
Langefeld European Americans rs223881 16 57386566 PLLP, CCL22 1.14 28714469 Down NA
Molineros Asian and European rs223881 16 57386566 CCL22 0.87 28108556 Down NA
Langefeld European Americans rs223883 16 57388730 PLLP, CCL22 1.15 28714469 NA NA
Langefeld Hispanic American rs2550333 16 58267472 CSNK2A2, CCDC113 1.28 28714469 NA NA Langefeld Hispanic American rs2731763 16 58280078 CSNK2A2, CCDC113 1.31 28714469 NA NA
Morris Chinese and European rs1170426 16 68603798 ZFP90 1.12 27399966 NA NA
Langefeld African American rs1170436 16 68607486 ZFP90 1.31 28714469 NA NA
Langefeld European Americans rs1170436 16 68607486 ZFP90 1.17 28714469 NA NA
Sheng Chinese rs2934498 16 85968282 IRF8 1.25 25890262 NA Signaling
Bentham European, African
American and Asian rs11644034 16 85972612 IRF8 1.25 26502338 Up Signaling
Cunninghame UK, American and Swedish rs2280381 16 86018633 IRF8 1.11 22046141 NA Signaling
Bentham European rs2286672 17 4712617 PLD2, INCA1 1.25 26502338 Down NA
Wen Chinese rs4792801 17 16845467 TNFRSF13B 0.892 29233832 Down NA
Bentham European rs2941509 17 37921194 IKZF3 1.35 26502338 Up NA
Langefeld European Americans rs930297 17 73404537 GRB2 0.83 28714469 NA NA
Langefeld European Americans rs1463485 17 73851791 GRB2 1.14 28714469 NA NA
Sun Asian rs1610555 18 69875911 CD226 1.19 26808113 NA NA
Kim [42] European, African, Hispanic, and Korean
rs3093030 19 10397403 ICAM1, ICAM4, ICAM5 1.16 22523428 Up NA Cunninghame UK, American and Swedish rs280519 19 10472933 TYK2 1.2 22046141 NA Signaling
Bentham European rs2304256 19 10475652 TYK2 1.24 26502338 NA Signaling
Langefeld European Americans rs11673460 19 18191621 LRRC25, SSBP4 0.86 28714469 Down NA
Langefeld European Americans rs425648 19 18202112 LRRC25, SSBP4 0.9 28714469 NA NA
Langefeld European Americans rs12971295 19 18517331 LRRC25, SSBP4 0.88 28714469 NA NA Langefeld European Americans rs13344313 19 18517767 LRRC25, SSBP4 0.88 28714469 NA NA
Sun Asian rs2305772 19 51530488 SIGLEC6 0.86 26808113 NA NA
Vazgiourakis [43]
Greek and Turkey rs4810485 20 44747947 CD40 0.63 21914625 Up NA
Armstrong European rs11697848 20 48575315 RNF114 2.115 24871463 Up NA
Han Chinese rs463426 22 21809185 UBE2L3, YDJC, HIC2 0.78 19838193 NA NA
Han Chinese rs131654 22 21917190 HIC2-UBE2L3 0.78 19838193 NA NA
Bentham European rs7444 22 21976934 UBE2L3 1.27 26502338 NA NA
Langefeld Hispanic American rs229533 22 37587111 C1QTNF6 1.24 28714469 NA NA
Langefeld Hispanic American rs229541 22 37591318 C1QTNF6 1.27 28714469 NA NA
Sun Asian rs61616683 22 39359768 SYNGR1 0.79 26808113 NA NA
Zhang [44] Asian rs7062536 23 12839152 PRPS2 0.84 25149475 Up NA
Shen [45] Asian rs3853839 23 12907658 TLR7 2.33 20733074 Up Production
Bentham European rs887369 23 30577846 CXorf21 1.15 26502338 Up NA
Zhu [46] Chinese rs5914778 23 56758231 LINC01420 1.32 26635088 NA NA
Zhang, Jacob [47]
European Americans, African Americans, Asian Americans and Hispanic Americans
rs17422 23 153227426 NAA10, HCFC1, TMEM187 0.75 25149475,
19329491 NA NA
Bentham European rs1734787 23 153325446 IRAK1, MECP2 1.31 26502338 NA Production
REFERENCES
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