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Supplemental Digital Content 1. Demographics and presenting signs/

symptoms of patients admitted for measles (n=33)

Number (%) / Median (IQR) Patient age

<12 months 3 (9)

12-23 months 10 (30)

24-59 months 17(52)

>59 months 3 (9)

Sex, Male 16 (48)

Race

Black/ African American 31 (94)

Asian 2 (6)

Somali ethnicity 24 (73)

Primary Payer

Medical Assistance 29 (88)

Commercial 3 (9)

Self Pay 1 (3)

Previously Healthy 24 (73)

Weight/ BMI

Weight Percentile, range 1.4 – 99.98% 40 (16, 86) Body Mass Index Percentile, range 0 – 99.6%, n=20d 36 (17, 85) Admission Year

2011 8 (24)

2014-2016 4 (12)

2017 21 (64)

Measles Immunization Statusa

Not age-eligibleb 3 (9)

0, Delayed for age 27 (82)

1, Up to date for age 1 (3)

1, Delayed for age 1 (3)

Unknown 1 (3)

Days of Illness, range 2-12 days 5 (4,6) Presenting Signs & Symptomsc

Fever 33 (100)

Poor feeding 32 (97)

Cough 31 (94)

Rash 29 (88)

Conjunctivitis 25 (76)

Coryza 24 (73)

Vomiting 16 (49)

Koplik spots 13 (39)

Diarrhea 12 (36)

Difficulty breathing 8 (24)

Lab Abnormalitiesd

Aspartate transaminase >50 units/L, n=16 12 (75) Absolute lymphocyte count <2.0x 103/uL, n=19 14 (74)

Albumin <3.4 g/dL, n=16 9 (56)

Hemoglobin <11.5 mg/dL, n=26 11 (42)

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Calcium ≤8 mg/dL, n=31 12 (39)

Sodium <135 mEq/L, n=31 11 (35)

WBC <5.0x 103/uL, n=26 8 (31)

CRP >2.9 mg/dL, n=18 5 (28)

Alanine transaminase >65 units/L, n=16 1 (6.3)

aMMR immunization >21 days prior to symptom onset bPatients were < 12 months age were categorized as age ineligible. cPer patient report or initial exam dFirst lab within 24 hours of hospital admission eBMI percentile not available for children <2 years. One patient did not have height taken.

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