TABLE 3. Patient data Patient Number
(Age, sex, health)
Type of surgery and implant
Peg time and type
Onset of infection from pegging and
presentation Follow-up from onset of infection
Exposure and treatment
Conjunctival culture
Systemic antibiotic treatment
Follow-up duration (from
infection) Final status 1 (40, F, well) Evis/SHA 8 mo
HA-Tps
33 mo Severe
3 consecutive negative cultures, no response to empirical antibiotics, peg fell out, implant explored and samples from the implant cultured
-- Fusobacterium
+ Bacteroides
Oral- ciprofloxacin, ornidazole (2 wk)
32 mo Resolution, implant retained, no peg, free of symptoms for 13 mo.
2 (29, F, well) Evis/PP 7 mo TP
9 mo Severe
Responded well to empirical antibiotics + (2 mo after infection) scleral graft
Negative I.M.- ceftriaxone (1 wk)
80 mo Resolution, implant retained, free of symptoms for 78 mo.
3 (40, F, well) Enuc/CHA 13 mo AC
83 mo Severe
Responded well to empirical antibiotics -- Negative I.M.- ceftriaxone (1 wk)
43 mo Resolution, implant retained, free of symptoms for 42 mo.
4 (29, F, well) Enuc/CHA 9 mo AC
64 mo Severe
Peg fell out, replaced 2 mo later with a HA- Tps, responded well to empirical antibiotics
-- Negative I.M.- ceftriaxone
(1 wk)
60 mo Resolution, implant retained, peg replaced, free of symptoms for 60 mo.
5 (24, F, well) Evis/PP 6 mo TP
39 mo Mild
Responded well to antibiotics, 4 quiescent periods lasting for 18, 8, 5, and 6 mo, infection persisted after closure of exposure, implant removed (3 yr after infection) and replaced with a bone-derived HA implant
+ (18 mo after infection) f. lata
S pyogenes Oral- ciprofloxacin, ornidazole (2 wk)
41 mo Resolution, implant removed, free of symptoms for 4 mo.
6 (56, M, well) Evis/AL 8 mo HA-Tps
11 mo Mild
Responded moderately to antibiotics, 2
relatively quiescent periods lasting for 4 and 6 mo
-- S aureus Oral- ciprofloxacin, ornidazole (2 wk)
12 mo Hemorrhagic purulent discharge and
discomfort on last visit, removal may be
required 7 (38, M, well) Sec/AL 11 mo
HA-Tps
3 mo Mild
Responded well to antibiotics -- S aureus +
S pneumoniae
Oral- amoxicillin+
clavulanic acid (2 wk)
13 mo Resolution, implant retained, free of symptoms for 13 mo.
8 (27, M, well) Sec/CHA 6 mo PCps
78 mo Mild
Responded moderately to antibiotics, 3 relatively quiescent periods lasting for 8, 10, and 5 mo
+ (concurrent with infection) spon. closure 4 mo
S epidermidis Oral- amoxicillin+
clavulanic acid (2 wk)
24 mo Purulent discharge, conjunctival thinning and severe chemosis on last visit, removal may
be required
9 (42, M, well) Enuc/AL 6 mo HA-Tps
23 mo Mild
Responded moderately to antibiotics, 2 exposures during the course, 2 quiescent periods lasting for 10 and 12 mo
+ (concurrent with infection) scleral graft and f. lata
S aureus I.M.- ceftriaxone (1 wk)
26 mon Resolution, implant retained, free of symptoms for 12 mo.
10 (29, F, well) Evis/AL 23 mo HA-Tps
6 mo Mild
2 surgeries for severe enophthalmos, superior sulcus deformity, and ptosis during the year before infection, responded well to antibiotics
+ (24 mo before infection) spon.
closure 2 wk
S aureus Oral- amoxicillin+
clavulanic acid (2 wk)
7 mo Resolution, implant retained, free of symptoms for 8 mo.
11 (40, F, well) Sec/AL 9 mo HA-Tps
50 mo Mild
Responded moderately to antibiotics, 1 quiescent period lasting for 5 mo
-- Coagulase (-)
Staph + Strep pyogenes
Oral- amoxicillin+
clavulanic acid, ornidazole (2 wk)
7 mo Hemorrhagic purulent discharge and pyogenic granuloma on last visit, removal may be
required
SHA indicates synthetic hydroxyapatite; CHA, coralline hydroxyapatite; PP, porous polyethylene; AL, aluminium oxide; HA-Tps, HA-coated, titanium-sleeved titanium peg; TP, titanium post for PP implants; AC, acrylic peg; PCps, polycarbonate sleeve and peg.
