Table S1. Demographics and clinicopathologic characteristics of matched hospitalized moderate-severe direct ARDS patients with hypertension.
Factors Pre-matched
(n=307)
Post-matched (n=186)
Male, % 236 (76.9%) 148 (79.6%)
Age 74.0 (66.0, 80.0) 75.0 (67.0-80.0)
Smoke 188 (61.2%) 119 (64%)
Alcohol 133 (43.3%) 87 (46.8%)
Hypertension Grade
I 254 (82.7%) 159 (85.5%)
II 53 (17.3%) 27 (14.5%)
Pre-existed comorbidity
Coronary Artery Disease 61 (19.9%) 37 (19.9%)
Diabetes Mellitus 81 (26.4%) 46 (24.7%)
Laboratory findings
PaO2/FiO2 ratio 118.0 (92.0, 160.0) 125.5 (90.0-161.0) Categories of ARDS
Moderate 202 (65.8%) 128 (68.8%)
Severe 105 (34.2%) 58 (31.2%)
WBC 9.7 (6.9, 13.0) 9.7 (8.2-13.5)
Hb 109.0 (91.0, 126.0) 106.0 (91.0-120.0)
Plt 136.0 (90.0, 196.0) 152.0 (106.0-198.0)
ALB 31.6 (27.4, 34.5) 30.8 (26.0-34.5)
Cr 86.0 (57.0, 120.0) 88.9 (55.0-116.0)
Bun 11.2 (8.1, 17.0) 11.2 (8.1-16.6)
LDH 353.0 (258.0, 561.0) 367 (258.0-561.0)
Lac 2.1 (1.5, 2.8) 2.1 (1.5-2.8)
CRP 103.0 (35.0, 156.0) 109.0 (35.0-179.0)
PCT 0.8 (0.3, 3.3) 0.8 (0.3-5.2)
APACHE II score 9.0 (7.0, 12.0) 9.0 (7.0-12.0)
SOFA score 3.0 (2.0, 4.0) 3.0 (2.0-4.0)
Outcomes
Mechanical Ventilation 245 (79.8%) 148 (79.6%)
Duration of ventilation 10.0 (2.0, 17.0) 9.0 (2.0-17.0)
Shock 113 (36.8%) 73 (39.2%)
In hospital mortality 163 (53.1%) 99 (53.2%)
Hospital length of stay 17.0 (11.0, 24.0) 16.0 (12.0-23.0)
Continuous variables are expressed as median values (interquartile ranges), and categorical variables are presented as number of patients (percentages).
Abbreviations: ARDS, acute respiratory distress syndrome; DCCB, dihydropyridine calcium channel blockers; P/F, PaO2/FiO2; Lac, lactate; Hb,
hemoglobin; hct, hematocrit; Plt, platelets; ALB, albumin; Cr, creatinine; BUN, Blood Urea Nitrogen; LDH, lactate dehydrogenase; Lac, lactate; PCT, procalcitonin; WBC, white blood cell; CRP, C-reactive protein; ICU, intensive care unit; APACHE II, Acute Physiology and Chronic Health Evaluation II;
SOFA, sequential organ failure assessment;