Table S1. Individual patient characteristics and laboratory tests at the start of continuous renal replacement therapy.
Case Age Yr
Sex BMI kg/m2
Apache- IV score
Creatinine µmol/L
Indication for start of CVVH
Interval between
first COVID-19 symptoms and start
of CRRT (days)
CRP mg/L (normal-
value
<5)
Fibrino- gen g/L (normal- range 2.0-3.9)
D-dimer µg/L (normal-
value
<500)
Nor- adrenalina
dose µg/kg/min
Trombo- embolic events
Cumulative fluid balance during CRRT
treatment (L)
Bleeding compli-
cation
Outcome
1 58 M 31 73 706 Anuria 18 556 9.2 28186 None Pulmonary
embolus
- 1.24 - ICU
discharge
2 64 M 26 65 368 Anuria 15 411 6.0 9322 0.088 Pulmonary
embolus
+1.13 - Deceased
3 69 F 23 62 341 Anuria 7 114 6.8 1924 0.061 - -1.80 Intracra-
nialb ICU discharge
4 62 M 39 54 427 Anuria 20 306 9.4 5464 0.08 Suspected
pulmonary embolusc
-.05 - Deceased
5 78 M 30 136 248 Anuria 29 12 3.6 - 0.053 - +13.06 Gastro-
intestin alb
Deceased
6 61 M 28 69 531 Hyper-
kaliemia
17 397 6.4 - None Pulmonary
embolus
+1.57 - ICU
discharge
7 37 M 28 42 566 Emergingd 31 175 9.2 1689 0.21 Pulmonary
embolus
-1.72 -1.09e
- ICU
discharge
8 54 M 30 55 163 Hyper-
kaliemia
32 116 4.8 1016 0.159 Pulmonary
embolus
-7.66 - ICU
discharge
9 54 M 27 54 590 Emergingf 17 309 7.3 2885 0.085 - -2.51 - ICU
discharge
10 55 M 29 85 341 Anuria &
Hyper- kaliemia
34 305 7.7 - 0.183 Pulmonary
embolus Deep venous thrombosis
+6.91 - Deceased
11 69 M 29 96 541 Anuria 13 45 3.2 5886 0.19 - -6.24 - Deceased
aOnly noradrenalin as a vasopressor was used.
bDiagnosed during anticoagulation with regional citrate anticoagulation and continuous intravenous heparin with a higher APTT range.
cThe patients marginal clinical condition obstructed the performance of a computer tomography. Therapeutic doses of nadroparin were prescribed.
dMeasured creatinine clearance < 6 ml/minute, BUN 40 mmol/L and opportunity to start RRT (not in prone position during a short time frame).
eTwo CRRT treatment episodes.
fMeasured creatinine clearance < 6 ml/minute, BUN 37 mmol/L, daily increase in serum creatinine >100 µmol/L/day.