Table S1. Study Demographic Data of Articles Meeting Inclusion Criteria Publication Year No. of

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Table S1. Study Demographic Data of Articles Meeting Inclusion Criteria Publication Year No. of

Pts Age Range, y (mean)

Sex Country of

Origin Material

Used F/U

Range (mean) Chen et al ⁷ 2017 6 5-11 (7.6) 4 M: 2 F China Medpor 6-19 mo

(10.3) Constantine et al ⁸ 2014 17 (6.9) NR USA Medpor 2-6 y Habiballah et al ⁹ 2000 10 NR NR Saudi

Arabia Medpor NR Hempel et al ¹⁰ 2014 10 M, 23-44

(35) F,18-62 (39)

6 M:4 F Germany Porous

polyethylene 7-77 mo (24)

Kludt et all ¹¹ 2014 15 6-12 (7) 8M:7F NR Medpor 6 mo-5 y Ohmori et al ¹² 1979 93 3-26 2M:1F Japan Silastic

Frame 6 mo-4 y Ohmori et al ¹³ 1984 34 3-29 30M:26

F Japan Silastic

Frame 2-9 y

Romo et al ¹⁴ 2008 26 NR NR USA Medpor 2 y

Romo et al ¹⁵ 2009 25 6-14 (9.4) NR USA Medpor 6-60 7 (35 mo)

Simsek et al ¹⁶ 2012 1 17 1F USA Medpor 1 y

Tai et al ¹⁷ 2006 42 9-10 (9) NR Japan Ceratite NR Wellisz et al ¹⁸ 1993 18 7-41 (26) 12M:6F USA Medpor (10 mo) Zhang et al ¹⁹ 2009 117 6-39 (16.7) 68M:49

F China EH

composite 6-24 mo

Zhao et al ²⁰ 2009 355 NR NR China Medpor 3 mo-5 y

Abbreviations: EH, mixture of epoxide acrylate malelic and hydroxyapatite; F, female;

F/U,follow-up; M, male; NR, not reported; Pts, patients.

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Table S2. Adverse Event Data Stratified by Study and Alloplastic Implant Type

Chen Consta

ntine Habiballah Hempel Kludt Ohmori

(1979) Ohmori (1984) Romo

(2006) Romo

(2007) Simsek Tai Wellisz Zhang Zhao

Totals Material

^Medpor ^Medpor ^Medpor ^Porous_polyethyl

ene

Medpor Silicone Silicone Medpor Medpor Medpor Ceratite Medpor EH

Composite Medpor

- Indication

^Unilater_al

Microti a

Microtia Congenital or traumatic defect

Partial acquired auricular defect

Microtia Microtia Microtia Microti

a Microti

a Auricul

ar defect caused by high- energy trauma

Microtia Burn Microtia Auricular defect

-

Adverse Events

16.67%

implant exposur e due to TPFF loss, salvaged with temporo p arietal fascia transfer and skin grafting

5.88%

infection and extrusion

10% infection;

10% exposure;

10% poor cosmetic outcome;

10% extrusion

; 70%

explantat ion (30%

partial removal and 40%

total removal)

20% poor cosmetic outcome;

20% extrusion 6.67%

partial exposu re

No adverse events noted in this study

30% poor cosmetic outcome where framework had to be removed due to postopera tive infection s or auricular traumas received a few years after the complete auricular operation

7.7%

graft exposur e

4% hemato ma; 24%

dehiscen ce <1cm

100 inflamm ation

None 11%

exposure of framewo rk

1.7% poor cosmetic outcome;

0.85%

extrusion

0.28%

infection;

13.5%

exposure

-

Infection 0 1 1 0 0 0 0 0 0 0 0 0 0 1 3

Inflammatio

n 0 0 0 0 0 0 2 0 0 1 0 0 0 0 3

Explantation 0 0 7 0 0 0 6 0 0 0 0 0 0 0 13

Migration 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Hematoma 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1

Dehiscence 0 0 0 0 0 0 0 0 6 0 0 0 0 0 6

Poor

Cosmesis 0 0 1 2 0 0 6 0 0 0 0 0 2 0 11

Extrusion 1 1 1 2 1 0 0 2 0 0 0 2 1 48 59

Fistula 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1

Abbreviation: TPFF, temporoparietal fascia flap

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Table S1. Study Demographic Data of Articles Meeting Inclusion Criteria Publication Year No. of