Univariate Linear Regressions of SF-36 Overall Quality of Life Scores

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Univariate Linear Regressions of SF-36 Overall Quality of Life Scores

Variable Coefficient Standard

Error p-value 95% Confidence Interval Lower Bound Upper Bound

Frailty* -20.07 1.78 <0.001 -23.57 -16.58

Age 0.07 0.10 0.476 -0.12 0.27

Male* 7.12 1.97 <0.001 3.25 10.99

Prior Transplant 5.93 8.31 0.476 -10.39 22.26

Transplanted During Study 0.46 2.48 0.852 -4.41 5.33

Listed During Study* 4.05 1.98 0.041 0.17 7.93

Number of Days Listed 0.002 0.001 0.165 -0.0007 0.004

Days before Transplant -0.001 0.009 0.887 -0.019 0.016

BMI -0.11 0.14 0.440 -0.38 0.17

Height (m) 9.77 7.74 0.208 -5.45 24.98

Weight (kg) 0.03 0.04 0.487 -0.05 0.11

Creatinine* -3.31 1.12 0.003 -5.50 -1.12

Bilirubin* -0.53 0.17 0.002 -0.87 -0.20

Albumin* 8.49 1.39 <0.001 5.77 11.22

INR* -6.93 2.60 0.008 -12.04 -1.83

Sodium* 0.97 0.17 <0.001 0.63 1.31

MELD* -0.73 0.15 <0.001 -1.03 -0.44

Dialysis* -10.48 6.36 0.100 -22.97 2.01

Ascites* -5.24 2.01 0.009 -9.18 -1.29

Encephalopathy* -8.16 1.96 <0.001 -12.02 -4.30

Tobacco Use* -8.16 2.58 0.002 -13.23 -3.08

PVD -4.62 7.78 0.553 -19.90 10.66

CAD* -7.68 4.03 0.058 -15.61 0.25

Diabetes* -3.38 2.22 0.128 -7.75 0.98

Hypertension -1.29 2.07 0.532 -5.36 2.77

COPD* -6.56 4.24 0.122 -14.89 1.77

CHF -3.49 8.96 0.697 -21.10 14.12

Hepatitis C Virus* -3.21 2.18 0.141 -7.49 1.07

HCC 5.11 2.94 0.083 -0.67 10.88

Income in Thousands* 0.16 0.07 0.023 0.02 0.30

NASH -1.26 3.23 0.696 -7.61 5.09

Hepatitis B Virus 6.22 5.54 0.262 -4.67 17.11

Fulminant Liver Disease* -16.51 8.28 0.047 -32.78 -0.24

Cholestatic Liver Disease 2.89 2.89 0.317 -2.78 8.57

Cancer* 4.06 2.78 0.145 -1.40 9.53

Autoimmune Disease -0.87 4.66 0.853 -10.03 8.30

Other Diagnosis 3.69 2.63 0.161 -1.47 8.84

Alcoholism -0.11 2.19 0.961 -4.40 4.19

*Denotes variables with a p<0.250 and inclusion in multivariate analysis

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Multivariate Linear Regression of SF-36 Overall Quality of Life Scores

Frailty -16.34 1.83 <0.001 -19.94 -12.74

Male 7.79 1.76 <0.001 4.33 11.25

Income in Thousands 0.13 0.06 0.033 0.01 0.25

Albumin 1.75 1.51 0.246 -1.21 4.70

Sodium 0.41 0.17 0.016 0.08 0.73

Fulminant Liver Disease -12.13 7.19 0.093 -26.26 2.01

Hepatitis C Virus -4.14 1.93 0.032 -7.93 -0.35

Encephalopathy -4.99 1.73 0.004 -8.39 -1.58

Tobacco Use -7.24 2.24 0.001 -11.64 -2.85

CAD -6.83 3.53 0.054 -13.77 0.11

MELD -0.24 0.16 0.146 -0.55 0.08

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Univariate Linear Regressions of SF-36 Physical Quality of Life Scores

Frailty* -9.72 0.68 <0.001 -11.05 -8.39

Age 0.12 0.11 0.296 -0.10 0.33

Male* 6.28 2.18 0.004 1.98 10.57

Prior Transplant* 10.66 9.16 0.245 -7.34 28.66

Listed During Study* 4.85 2.18 0.026 0.57 9.13

Number of Days Listed* 0.002 0.001 0.098 -0.0004 0.005

Days before Transplant 0.004 0.009 0.645 -0.014 0.022

BMI -0.10 0.15 0.516 -0.40 0.20

Height (m) 4.03 8.56 0.638 -12.78 20.84

Weight (kg) 0.01 0.05 0.838 -0.08 0.10

Creatinine* -3.91 1.23 0.002 -6.33 -1.50

Bilirubin* -0.67 0.19 <0.001 -1.03 -0.30

Albumin* 10.11 1.52 <0.001 7.13 13.10

INR* -9.24 2.86 0.001 -14.86 -3.63

Sodium* 1.20 0.19 <0.001 0.83 1.58

MELD* -0.86 0.17 <0.001 -1.19 -0.54

Dialysis* -10.16 7.03 0.149 -23.97 3.65

Ascites* -6.58 2.21 0.003 -10.93 -2.23

Encephalopathy* -7.89 2.18 <0.001 -12.17 -3.61

Tobacco Use* -8.61 2.86 0.003 -14.22 -2.99

PVD -2.99 8.60 0.728 -19.89 13.90

CAD* -8.17 4.46 0.068 -16.94 0.60

Diabetes* -3.69 2.46 0.134 -8.51 1.14

Hypertension 0.74 2.29 0.748 -3.75 5.23

COPD* -8.24 4.68 0.079 -17.44 0.96

CHF -6.63 9.91 0.504 -26.09 12.84

HCC* 7.08 3.24 0.029 0.72 13.44

Income in Thousands* 0.23 0.08 0.003 0.08 0.38

Cancer* 5.69 3.07 0.064 -0.34 11.71

NASH -0.44 3.57 0.903 -7.44 6.57

Hepatitis C Virus* -3.81 2.40 0.113 -8.53 0.90

Hepatitis B Virus 4.57 6.12 0.456 -7.46 16.60

Fulminant Liver Disease* -18.24 9.14 0.046 -36.19 -0.29

Cholestatic Liver Disease* 3.90 3.18 0.221 -2.36 10.16

Autoimmune Disease 0.17 5.15 0.974 -9.95 10.28

Other Diagnosis 3.13 2.90 0.281 -2.57 8.83

Alcoholism 0.43 2.41 0.859 -4.31 5.16

*Denotes variables with a p<0.250 and inclusion in multivariate analysis

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Multivariate Linear Regression of SF-36 Physical Quality of Life Scores

Frailty -18.66 2.01 <0.001 -22.61 -14.71

Hepatitis C Virus -4.63 2.12 0.030 -8.81 -0.46

Male 6.43 1.93 0.001 2.65 10.22

Tobacco Use -7.48 2.46 0.003 -12.31 -2.64

Albumin 2.45 1.66 0.140 -0.80 5.71

Sodium 0.60 0.18 0.001 0.23 0.96

Fulminant Liver Disease -14.45 7.92 0.069 -30.02 1.12

Income in Thousands 0.18 0.07 0.006 0.05 0.31

Encephalopathy -4.06 1.91 0.034 -7.81 -0.30

MELD -0.23 0.18 0.195 -0.58 0.12

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Univariate Linear Regressions of SF-36 Mental Quality of Life Scores

Frailty* -7.64 0.70 <0.001 -9.02 -6.27

Age 0.03 0.11 0.798 -0.18 0.24

Male* 7.96 2.10 <0.001 3.84 12.08

Prior Transplant 1.21 8.86 0.892 -16.20 18.61

Listed During Study* 3.26 2.11 0.123 -0.89 7.40

Number of Days Listed 0.001 0.001 0.387 -0.001 0.004

Days before Transplant -0.007 0.01 0.501 -0.03 0.01

BMI -0.11 0.15 0.438 -0.41 0.18

Height (m)* 15.50 8.24 0.060 -0.68 31.68

Weight (kg) 0.05 0.05 0.275 -0.04 0.14

Creatinine* -2.71 1.19 0.024 -5.05 -0.36

Bilirubin* -0.40 0.18 0.030 -0.76 -0.04

Albumin* 6.87 1.50 <0.001 3.92 9.82

INR* -4.62 2.78 0.097 -10.09 0.85

Sodium* 0.74 0.19 <0.001 0.37 1.11

MELD* -0.60 0.16 <0.001 -0.92 -0.29

Dialysis* -10.80 6.77 0.111 -24.09 2.50

Ascites* -3.90 2.14 0.070 -8.11 0.32

Encephalopathy* -8.43 2.09 <0.001 -12.54 -4.32

Tobacco Use* -0.1 2.75 0.005 -13.11 -2.29

PVD -6.25 8.27 0.450 -22.51 10.01

CAD* -7.19 4.30 0.095 -15.63 1.26

Diabetes* -3.08 2.37 0.193 -7.73 1.56

Hypertension* -3.32 2.20 0.132 -7.64 1.00

COPD -4.88 4.51 0.281 -13.75 3.99

CHF -0.35 9.53 0.971 -19.08 18.38

Hepatitis C Virus -2.60 2.32 0.263 -7.16 1.96

HCC 3.14 3.14 0.318 -3.03 9.31

Income in Thousands* 0.09 0.07 0.215 -0.05 0.24

Cancer 2.44 2.97 0.412 -3.40 8.27

NASH -2.09 3.44 0.544 -8.85 4.68

Hepatitis B Virus* 7.87 5.90 0.183 -3.73 19.47

Fulminant Liver Disease* -14.79 8.83 0.095 -32.14 2.57

Cholestatic Liver Disease 1.88 3.08 0.541 -4.17 7.93

Autoimmune Disease -1.90 4.97 0.703 -11.67 7.87

Other Diagnosis* 4.24 2.80 0.130 -1.25 9.74

Alcoholism -0.64 2.33 0.784 -5.22 3.94

*Denotes variables with a p<0.250 and inclusion in multivariate analysis

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Multivariate Linear Regression of SF-36 Mental Quality of Life Scores

Frailty -15.16 2.00 <0.001 -19.09 -11.23

Encephalopathy -5.88 1.94 0.003 -9.70 -2.06

Male 8.74 1.94 <0.001 4.92 12.56

Hypertension -3.62 2.01 0.073 -7.57 0.34

Tobacco Use -6.92 2.51 0.006 -11.86 -1.98

Other Diagnosis 5.09 2.56 0.047 0.06 10.13

Sodium 0.31 0.18 0.089 -0.05 0.67

MELD -0.23 0.16 0.156 -0.55 0.09