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2005-20062005-2006

1C:\data\sk\b.tek\b.t.\1.pm5

ACADEMIC REGULATIONS COURSE STRUCTURE AND DETAILED SYLLABUS

BIO - TECHNOLOGY

B.TECH FOUR YEAR DEGREE COURSE

(Applicable for the batches admitted from 2005-2006)

JA W AHARL AL NEHRU TECHNOL OGICAL UNIVERSIT Y

KUKATPALLY, HYDERABAD - 500 072.

For

CODESUBJECTTPC

CS05143Computer Programming for Biotechnologists3+1*-6

HS05231English2+1*-4

EE05066Basic Electrical and Electronics Engineering3+1*-6

BT05273Fundamentals of Biology4+2*-8

MA05367Mathematics for Biotechnologists3+1*-6

BT05483Process Engineering Principles3+1*-6

ME05230Engineering Workshop Practice-34

CS05144Computer Programming Lab-34

EE05067Basic Electrical and Electronics Engineering Lab-34

HS05232English Language Communication Skills Lab-34

ME05220Engineering Drawing Practice Lab-34

Total251556

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

B.TECH. BIO-TECHNOLOGY

I Year

COURSE STRUCTURE

(2)

2005-20062005-2006

2C:\data\sk\b.tek\b.t.\1.pm5 CODESUBJECTTPC

BT05080Biochemistry4+1*-4

BT05079Biochemical Thermodynamics4+1*-4

BT05113Cell Biology4+1*-4

BT05276Genetics4+1*-4

BT05402Microbiology4+1*-4

BT05559Transport Phenomena in Bio Process4+1*-4

BT05081Biochemistry Lab-32

BT05114Cell Biology And Microbiology Lab-32

TOTAL 30628

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

B.TECH. BIO-TECHNOLOGY

COURSE STRUCTURE

II YearI Semester

CODESUBJECTTPC

BT05096Bioprocess Engineering4+1*4

CE05239Environmental Studies4+1*4

BT05319Instrumental Methods of Analysis4+1*4

HS05353Managerial Economics and Financial Analysis4+1*4

BT05413Molecular Biology4+1*4

MA05476Probability and Statistics4+1*4

BT05097Bioprocess Engineering Lab -I32

BT05320Instrumental Methods of Analysis Lab32

TOTAL30628 II YearII Semester CODESUBJECTTPC

BT05078Biochemical Reaction Engineering4+1*4

BT05071Basic Industrial Biotechnology4+1*4

BT05234Environmental Biotechnology4+1*4

BT05275Genetic Engineering4+1*4

BT05354Mass Transfer and Separation4+1*4

BT05454Plant Biotechnology4+1*4

BT05414Molecular Biology And Genetic Engineering Lab32

BT05455Plant Tissue Culture Lab32

TOTAL 30628

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

B.TECH. BIO-TECHNOLOGY

COURSE STRUCTURE

III YearI Semester

CODESUBJECTTPC

BT05084Bioinformatics4+1*4

BT05240Enzyme Engineering4+1*4

BT05286Heat Transfer in Bioprocesses4+1*4

BT05325Instrumentation and Process Control4+1*4

BT05304Immunology4+1*4

BT05502Regulatory Affairs and Clinical Trials4+1*4

BT05098Bioprocess Engineering Lab-II32

BT05305Immunology Lab32

TOTAL 30628 III YearII Semester

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2005-20062005-2006

3C:\data\sk\b.tek\b.t.\1.pm5 CODESUBJECTTPC

BT05134Computational Molecular Biology4+1*-4BT05076Bio Ethics, Bio Safety And Intellectual Property Rights4+1*-4

BT05099Biosensors and Bioelectronics4+1*-4BT05181Downstream Processing4+1*-4ELECTIVE –I4+1*-4

BT05100Biotechnology for Crop ImprovementBT05112Cancer Biology

BT05533Structural BiologyELECTIVE –II4+1*-4

BT05155Creativity Innovation and Product DevelopmentBT05416Molecular Pathogenesis

BT05383Metabolic EngineeringBT05085Bioinformatics Lab32

BT05182Downstream Processing Lab32

TOTAL30628

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

B.TECH. BIO-TECHNOLOGY

COURSE STRUCTURE

IV YearI Semester

CODESUBJECTTPC

BT05041Animal Cell Science and Technology4+1*-4ELECTIVE –III4+1*-4BT05262Food Science and TechnologyBT05415Molecular Modeling and Drug DesignBT05077Bio Process Economics And Plant DesignELECTIVE –IV4+1*-4BT05095Biopharmaceutical TechnologyBT05453Phytochemicals and Herbal MedicineBT05426Neuro Biology & Cognitive SciencesCA05315Industry Oriented Mini Project2CA05495Project Work12CA05515Seminar2

TOTAL15-28 IV YearII Semester

NOTE: All University Examinations (Theory and Practical) are of 3 hours duration.

*:TutorialsT:Theory periods per week P: Practical /Drawing Periods per weekC:Total Credits for the subject

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B. Tech. BTT P C

3+1 0 6

(CS05143) COMPUTER PROGRAMMING FOR BIOTECHNOLOGISTS

UNIT – I: Hardware

Parts of a computer: Processor, memory, I/O devices, storage devices, Types ofcomputer systems: Super computer, Mainframe computer, Minicomputer,workstations, Microcomputers, Personal computers, desktop handheld computers.

Input Devices: keyboard, mouse, hand devices, optical devices, audiovisual devices.Output devices: monitor, projectors, sound devices, printers, storage devices, files.

UNIT-II: Software

Principles of software Engineering operating systems and their applications. DOS,WINDOWS, UNIX, LINUX.

UNIT - III

Algorithm, flowchart, program development steps, basic structures of C language,

data types, declaration of variables, assigning values, arithmetic, relational andlogical operators, increment and decrement operators, WHILE, DO-WHILE and

FOR statements.

UNIT – IV

One dimensional & two dimensional arrays, initialization, string variables, declaration

reading and writing.

UNIT-V

Functions, Basics of functions variables & storage classes, example C programs.

UNIT – VI

Structure definition, initializing, assigning values, passing of structures as arguments,

unions. Databases: 1) RDBMS and DBMS 2) CODD’s Rules 3) Normalisation.

UNIT – VII

Infix, programs, recursion in C, Queue & it’s sequential representation, Circular

queue, Sequence.

UNIT-VIII: Biopackages

1)Biopearl 2) BioJava 3) Systems Biology Markup Lanaguage.(SBML)

REFRENCE:

1.E. Balaguru Swamy, C & Data Structures, TMH, 2002.

2.A.M. Tanenbaum, Data Structures using C, PHI.

3.Horowitz and Sahani, Fundamentals of Data Structures, Wiley.

4.Mastering Perl for Bioinformatics by James D. Tisdall , O’ Reilly publications.

Objective of this course is to enable the student to apply the knowledge gained

here for Bioinformatics Applications

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABADT P CI Year B-TECH B.T.2+1 0 4

(HS 05231) ENGLISH

1.INTRODUCTION :

In view of the growing importance of English as a tool for global communica-tion and the consequent emphasis on training students to acquire communi-cative competence, the syllabus has been designed to develop linguistic andcommunicative competence of Engineering students. The prescribed booksand the exercises are meant to serve broadly as students’ handbooks, toencourage them to develop their language skills. The two textbooks identifiedby the Board of Studies serve the purpose of illustrating the conceptual frame-work within which the syllabus is to be administered in the classroom. When atextbook is prescribed content is generally paid attention to. However, thestress in this syllabus is on language acquisition and skill development, call-ing for both the teacher and the taught to go beyond the prescribed texts andinnovate exercises and tasks.

2.OBJECTIVES :

1.To promote the language proficiency of the students with emphasis on im-proving their LSRW skills.

2.To impart training to the students through the syllabus and its theoretical andpractical components.

3.To improve communication skills in formal and informal situations.

3.SYLLABUS :

Listening Skills :

•Listening for general content

•Listening to fill up information gaps•Intensive listening

•Listening for specific information

•Note-taking - guided and unguided

•Post-listening testingSpeaking Skills :

•Oral practice

•Developing confidence

•Introducing oneself/others•Asking for/ giving information

•Describing objects/offering solutions

•Describing situations

•Role play

•Expressing agreement/disagreement Reading Comprehension•Skimming the text•Understanding the gist of an argument

•Identifying the topic sentence

•Inferring lexical and contextual meaning

•Understanding discourse features

•Recognizing coherence/sequencing of sentencesNOTE :The student, through the training imparted to him/her by meansof the text-based approach, will be examined in answering questionson an unseen passage.

Writing Skills :

•Writing a sentence

•Use of appropriate vocabulary•Paragraph writing

•Coherence and cohesiveness

•Narration / description

•Interpreting data

•Formal and informal letter writing•Sending e-mails

•Information transfer

•Editing a passage

4.TEXTBOOKS PRESCRIBED :

In order to improve the proficiency of the student in the acquisition of the fourskills mentioned above, the following texts and course content, divided intoEight Units, are prescribed:

1.LEARNING ENGLISH: A Communicative Approach, Hyderabad: OrientLongman, 2005.(Selected Lessons)

2.WINGS OF FIRE: An Autobiography – APJ Abdul Kalam, Abridged ver-sion with Exercises, Hyderabad: Universities Press (India) Pvt. Ltd., 2004.

The following lessons from the prescribed texts are recommended for study:

A.STUDY MATERIAL :

Unit – I

1.Astronomy from LEARNING ENGLISH: A Communicative Approach, Ori-ent Longman, 2005.

2.Chapters 1-4 from Wings of Fire: An Autobiography – APJ Abdul Kalam, anabridged version with Exercises, Universities Press (India) Pvt. Ltd., 2004

Unit – II

3.Information Technology from LEARNING ENGLISH: A Communicative Ap-proach, Orient Longman, 2005.

4.Chapters 5-8 from Wings of Fire: An Autobiography – APJ Abdul Kalam, anabridged version with Exercises, Universities Press (India) Pvt. Ltd., 2004

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2005-20062005-2006

5C:\data\sk\b.tek\b.t.\1.pm5 Unit – III5.Humour from LEARNING ENGLISH: A Communicative Approach, OrientLongman, 2005.

6.Chapters 9-12 from Wings of Fire: An Autobiography – APJ Abdul Kalam,an abridged version with Exercises., Universities Press (India) Pvt. Ltd.,2004

Unit – IV

7.Environment from LEARNING ENGLISH: A Communicative Approach, Ori-

ent Longman, 2005.

8.Chapters 13-16 from Wings of Fire: An Autobiography – APJ Abdul Kalam,an abridged version with Exercises, Universities Press (India) Pvt. Ltd.,

2004

Unit – V

9.Inspiration from LEARNING ENGLISH: A Communicative Approach, OrientLongman, 2005.

10.Chapters 17-20 from Wings of Fire: An Autobiography – APJ Abdul Kalam,an abridged version with Exercises, Universities Press (India) Pvt. Ltd.,2004.

Unit – VI

11.Human Interest from LEARNING ENGLISH : A Communicative Approach,Orient Longman, 2005.

12.Chapters 21-24 from Wings of Fire: An Autobiography – APJ Abdul Kalam,an abridged version with Exercises, Universities Press (India) Pvt. Ltd.,2004.

* Exercises from the lessons not prescribed shall also be used for classroomtasks.

Unit – VII

Reading and Writing Skills

Reading Comprehension

Situational dialogues

Report writing

Letter writing

Essay writing

Information transfer

Unit – VIII

Remedial English

Common errors

Subject-Verb agreement

Use of Articles and Prepositions

Tense and aspect Vocabulary – Synonyms & Antonyms, one-word substitutes, prefixes &

suffixes, Idioms & phrases, words often confused.

TEXT BOOKS

1.Effective Technical Communication, M Ashraf Rizvi, Tata McGraw-Hill Pub-lishing Company Ltd.

2.Everyday Dialogues in English, Robert J Dixson, Prentice Hall of India PvtLtd., New Delhi.

REFERENCES

1.Strengthen Your English, Bhaskaran & Horsburgh, Oxford University Press

2.English for Technical Communication, K R Lakshminarayana, SCITECH

3.Strategies for Engineering Communication, Susan Stevenson & SteveWhitmore ( John Wiley and sons).

4.English for Engineers: With CD, Sirish Chaudhary, Vikas Publishing HousePvt. Ltd. With CD.

5.Basic Communication Skills for Technology, Andrea J Rutherfoord, PearsonEducation Asia.

6.Murphy’s English Grammar with CD, Murphy, Cambridge University Press

7.A Practical Course in English Pronunciation, (with two Audio cassettes),Sethi, Sadanand & Jindal , Prentice –Hall of India Pvt Ltd., New Delhi.

8.English for Professional Students, by S S Prabhakara Rao.

9.The Oxford Guide to Writing and Speaking, John Seely, Oxford.

10.Grammar Games, Renvolucri Mario, Cambridge University Press.

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

3+1 0 6

(EE05066) BASIC ELECTRICAL & ELECTRONICS ENGINEERING

(BIO-TECHNOLOGY)UNIT I ELECTRICAL CIRCUITSOhms Law -Kirchoffs Laws - steady state solution of D C Circuits - Introduction toAC circuits - Waveforms and RMS value - power and power factor, single phaseand three phase balanced circuits.UNIT IIELECTRICAL MACHINESPrinciples of operation and characteristics of D C machines, Transformers (singlephase and three phase) - Synchronous Machines - three Phase and single phaseinduction motors - (op. Principles).UNIT IIIMEASUREMENTSMoving coil and moving iron instruments (Ammeter and voltmeter). Dynamometertype watt meters and energy meters (op. Principles).UNIT IVSEMICONDUCTOR DEVICES & RECTIFIERSClassification of solids based on energy hand theory - Intrinsic semiconductors -Extrinsic semiconductors - P type and N type - P-N junction - V I characteristic of PNjunction diode - Zener diode - Zener diode characteristics - Half wave and full waverectifiers - Voltage regulation, SCR, Diac, Triac, Characteristics and simpleapplications.UNIT V TRANSISTORSBipolar junction transistor - CB, CE, CC - Configurations and characteristics - Biasingcircuits - Field Effect Transistor - Configurations and characteristics - FET amplifier- UJT - characteristics and simple applications - switching transistors - concept offeed back - negative feed back - application in temperature and motor speed control.UNIT VI AMPLIFIERSElementary treatment of voltage amplifier - Class A, B and C power amplifiers -principles of Tuned amplifiers.UNIT VII SIGNAL GENERATORS AND LINEAR IC’SSinusoidal oscillators - positive feed back - RC phase shift, Hartley, Colpit’s, Wienbridge Oscillators - multivibrators - operational amplifier - adder, multiplier, integratorand differentiators -Integrated circuits.UNIT VIII DIGITAL ELECTRONICSBinary number system - AND, OR, NOT, NAND, NOR circuits - Boolean algebra -Exclusive OR gate - Half and Full adders - flip flops - registers and counters - A/D,D/A conversion - Digital computer principle.TEXT BOOKS:1.Mittle, V.N., Basic Electrical Engineering, TMH Edition, New - Delhi, 19902.Del Taro, Electrical Engineering Fundamentals, Prentice Hall of India Pvt. Ltd.,New Delhi, Second edition.

REFERENCES

1.Millman & Halkias, Integrated Electronics, McGraw Hill, 1979.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

4+2 0 8

(BT05273) FUNDAMENT ALS OF BIOLOGY

Unit I: Introduction to MicroorganismsDiversity in biological systems, Cell biology and cell structure, Difference betweenProkaryotes & Eukaryotes. Kingdom systems. Five-kingdom classificationGeneral characters, Brief account on Ecology, Morphology, Nutrition, Locomotionand Reproduction, useful and harmful effects of Bacteria, Viruses, Algae, Fungiand Protozoans.

Unit II: Plant BiologyClassification of Plant Kingdom. Concepts of Growth, Meristems. Development ofdifferent plant organs; Plant growth regulators; Economic Importance of Plants,Biology of Pests in relation to Rice, Cotton, Sugarcane and Groundnut.

Unit III: Animal BiologyClassification of Animal Kingdom, Functions, morphology, growth and Reproduc-tion, economic importance. Phylogeny of Invertebrate & Vertebrate Phyla, Con-cepts of Species & Ecosystem. Protozoan Parasites – two important forms in man( Plasmodium, Entamoeba histolytica), Helminthes ( Fasciotopsis buski, Taeniasolium, Ascaris, Wucharia bancrafti)

Unit IV: Basic Molecular Biology

Genetics: DNA as genetic material, Structure of DNA, DNA replication,

Transcription, Translation, Genes to proteins to protein function, Gene expressionand regulation, Recombinant DNA technology.

Unit V: Human Biology IIntroduction of body as a whole, Cells and Tissue Organization, Electrolytes andBody fluids. Physiology of Blood. Digestive system, Respiratory system and Endo-crine system.

Unit VI: Human Biology II

Human Physiology: Biological axons and neurons, Neuromuscular and synapticjunctions, Sensory systems - hearing, taste, smell and visual receptors.

Unit VII: Introduction to BiotechnologyBiotechnology – definition, history, scope and importance, Drugs and Chemicalsfrom Plants & Animals. Definition and importance (in general) of Biofuels,Biofertilizers, Biopesticides, Bioindicators & Biosensors.

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2005-20062005-2006

7C:\data\sk\b.tek\b.t.\1.pm5 Unit VIII: Applications of BiotechnologyMicrobial enzymes; Single Cell Protein (SCP); Monoclonal Antibodies. Introductionto Transgenic Plants & Animals; Advantages and limitations of Genetically modi-fied crops and foods.TEXT BOOKS:1.Microbiology Pelczar M.J. Chan ECS and Krieg N.R, Tata McGraw Hill.2.Basic Biotechnology, Second Edition, by Colin Ratledge and BjormKristiansen, Cambridge University Press.

REFERENCES

1)Plant Physiology F.B Salisbury & C.W. Ross 4 th edition Thomson Wadsworth2)General Microbiology by Hons. G. Schlege, Cambridge University Press.3)A Textbook of Biotechnology by R.C. Dubey, S.Chand Publishers.4)Dr. C.C. Chatterjee, Human Physiology (11th Edition) Vol I and II, MedicalAllied Agency, Kolkata, 1987.5)Anatomy and Physiology In Health and Disease,K. J.W. Wilison andA. Waugh, Churchill & Livingston.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

3+1 0 6

(MA05367) MA THEMA TICS FOR BIOTECHNOLOGISTS

UNIT I: Differential Calculus

Introduction to Sets, Relations, Functions.

Concepts of limit, continuity, differentiation, product rule, quotient rule. Differentiation

of trigonometric, logarithmic, exponential functions. Applications of differentiation –

problems on tangent, sub tangent normal, sub normal. Introduction to partial

differentiation, Euler’s theorem.

Unit II: Integral Calculus

Introduction, Integration of different functions, methods of Integration, Integration

by parts. Concept of definite integrals. Applications of definite integrals – problems

on areas.

Unit III: Matrices

Types of matrices, determinants, Inverse of a square matrix, Solving of simultaneous

equations by Cramer’s method Matrix inversion method and Gauss Jordan methods.

Rank of a matrix, Echelon form. Solutions for linear equations. Eigen values and

Eigen vectors.

Unit IV: Ordinary Differential equations

Forming of differential equation by eliminating arbitrary constants, first order and

first degree – variables and separables, exact, homogeneous, linear and Bernoulli’s

equations.

UNIT-V : Bernoulli’s equations

Non-homogeneous Linear Differential Equations of Second and higher order with

constant coefficients with RHS term of the type -e ax sinax cosax Polynomials in x, eax V(x), xV(x) Applications to first order differential equations to growth and decay

problems

UNIT VI: Numerical Methods

Iterative Methods: Bisection, Newton Raphson, Successive approximation, Guass

Jordan and Guass siedel methods.

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2005-20062005-2006

8C:\data\sk\b.tek\b.t.\1.pm5 UNIT-VII:Interpolation, Lagrange interpolation, Newton’s forward difference, backward

difference and central difference interpolation methods. Numerical Integration by

Trapezoidal and Simpson’s rules, numerical solution to differential equations, Euler,

Ranga kutta methods.

Unit – VIII

Laplace Transforms

Laplace transforms of some standard functions, linear property, shifting theorems,

change of scale property, multiplication by powers of t, division by t.

Inverse Laplace Transforms - Shifting property, finding inverse laplace by partial

fractions, multiplication by powers of s, division by s.

Applications of laplace transforms for solving ordinary differential equations.

Mathematical Modelling in Biotechnology.

TEXT BOOKS:

1.A Text Book of Engineering Mathematics Volume-II, 2005 T,K.V.Iyengar,

B.Krishna Gandhi and others, S. Chand and Company.

2.Engineering Mathematics, B.V.Ramana, Tata McGraw-Hill 2003.

REFERENCES:

1.Engineering Mathematics-II, 2002, P.Nageswara Rao, Y.Narsimhulu,

Prabhakara Rao.

2.Engineering Mathematics, S.K.V.S. Sri Rama Chary, M.Bhujanga Rao, Shankar,

B.S.Publications 2000.

3.Advanced Engineering Mathematics (eighth edition), Erwin Kreyszig, John

Wiley & Sons (ASIA) Pvt. Ltd.2001.

4.Advanced Engineering Peter V.O’Neil Thomson Brooks/Cole.

5.Advanced Engineering Mathematics, Merle C.Potter, J.L.Goldberg, E.F.

Arbufadel, /oxford University Press. Third Edition 2005.

6.Numerical Methods: V N Vedamurthy, Iyengar N Ch N Vikas Pub. Reprint

2005.

7.Numerical Methods: S.Arumugam & others. Scitech Pub.

8.Elementary Numerical Analysis: An Algorithmic Approach: S.D.Conte and

Carl.D.E.Boor, Tata Mac-Graw Hill

9.Introductory Methods of Numerical Analysis: S.S.Sastry, Prentice Hall of India,

Pvt Ltd.,

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

3+1 0 6

(BT05483) PROCESS ENGINEERING PRINCIPLES

UNIT-IApplication of Engineering principles in biotech Industries-Introduction to unitoperations and unit processes–application of transport phenomenon principles(momentum, mass and heat transfer) in bioprocessing.

UNIT-IIUnits and dimensions, basic quantities and derived units. Conversion of units.Concept of mass and force, definition of gc and its utility. Various equations of stateincluding ideal gas law to evaluate P-V.T data, their application in process calculationsby solving some numerical problems.

UNIT-IIIFluid mechanics- Properties of fluids, fluid statics, energy balance in fluid flow throughpipes and condunits, Bernoulli’s equation and its application, calculation of powerrequired for pumping fluids. Examples from bioprocessing systems .

UNIT-IVRheology of fluids - Newton’s law of viscosity. Concept of Newtonian and non-Newtonian fluids- Different types of non-Newtonian fluids with examples inbioprocessing. Measurement of viscosity using extrusion rheometer, plate and coneviscometer, coaxial cylinder viscometer etc.UNIT-VFlow through pipes, average velocity, flow regimes, boundary layer concept. Laminarand turbulent flow – characterization by Reynold’s number, pressure drop due toskin friction and form friction, friction factor chart, Hagen -Poiseuille equation. Briefintroduction to flow of compressible fluids.

UNIT-VIFlow past immersed bodies: Definition of drag and drag coefficient. Friction in flowthrough beds of solids, derivation of friction factor equations and pressure dropexpressions. Introduction of the concept of packed beds. Motion of particles throughfluids, terminal velocity, concept of fluidization, mechanism of fluidization, fluidizedbeds and pressure drop in fluidized beds. Correlating the concept of packed bedsand fluidized beds with immobilized bioreactors.

UNIT-VIIFlow measuring and monitoring systems- valves, bends, elbows, prevention of leaks,mechanical seals, stuffing box. Flow measuring devices-manometers, orifice meter,venture meter and rotameter.

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2005-20062005-2006

9C:\data\sk\b.tek\b.t.\1.pm5 UNIT-VIIIFluid transportation machinery: Different types of pumps, positive displacementpumps, reciprocating pumps, diaphragm pumps, peristaltic pumps. Calculation ofpump horse power.

TEXT BOOKS:

1.Introduction to Biochemical Engineering, D.G.Rao, Tata Mc Hill (2005)2.Bio-process Engineering Principles, Pauline M.Doran. Academic press (1995)

REFERENCES:

1.Unit operations of chemical engineering,Mc Cabe, W.L, Smith J.C., and Harriot,P., Mc-Graw Hill, 3 rd Ed. (1993).

2.“Technical aspects of the rheological properties of microbial cultures“, - Charles,M (1978) in Advanmces in Biochemical Engineering, Ghose, T.K., Fiechter, Aand Blakebrough, N.(Eds), Spinger-Verlag, Berlin, pp. 1-62

3.Non-Newtonian Flow and Heat Transfer, Skelland, A.H.P. (1967), John Wileyand Sons, Inc., Newyork, 27-49.

4.Unit operation in Food processing, Earle, R.L. (1996) Pergamon Press, Oxford,PP. 212-282.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

T P C

I Year B-TECH B.T. 0 3 4

(ME05230) ENGINEERING WORKSHOP PRACTICE

SYLLABUS

1.TRADES FOR EXERCISES:

(Any seven trades from the following with minimum of three simple exercises

in each trade and also study of Tools used).

1.Carpentry

2.Fitting

3.Tin-Smithy and Development of jobs carried out and soldering.

4.Black Smithy

5.House-wiring

6.Foundry

7.Plumbing.

8.IT Workshop-I

9.IT workshop-II

IITRADES FOR DEMONSTRATION & EXPOSURE:

1.Demonstration of power tools – Pneumatic Tools, Electrical Tools

2.Welding - ARC Welding/Gas Welding/Plasma Welding

3.Machine Shop

4.Metal Cutting - Hacksaw, Power Saw, Gas Cutting, Arc Cutting.

Objective : The objective of this subject is to provide the basic concepts about

different manufacturing processes and also study of hardware used in IT industry.

The tools used are demonstration and simple exercises are given.

Question Paper pattern :

Lab record tools, procedure of usage etc. any two trades in end examination.

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I YEAR B.Tech. B.T.T P C0 3 4

(CS05144) COMPUTER PROGRAMMING LAB

1.Write a C program to evaluates the following algebraic expressions after reading

necessary values from the user:

a)ax+b/ax-b

b)2.5 log x + cos 32 0 + | x 2 –y 2 | + v 2xy c)1/α √√√√√2π e- (x-m/ √√√√√2σ)2

2.Write a C program for the following

a)Printing three given integers in ascending order

b)Sum of 1 + 2+ 3 + _ _ _ _ _ n

c)1 + x 2/2! + x 2/ 4!+ _ _ _ _ _ upto ten terms d)x +x 3/3! + x 5/5!+ _ _ _ _ _ upto 7 th digit accuracy

e)Read x and compute Y =1 for x > 0

Y=0 for x = 0

Y= -1 for x<0

3.Write C program using FOR statement to find the following from a given set

of 20 integers.

i) Total number of even integers.ii) Total number of odd integers.

iii) Sum of all even integers.iv) Sum of all odd integers.

4.Write a C program to obtain the product of two matrices A of size (3X3) and B

of size (3X2). The resultant matrix C is to be printed out along with A and B.

Assume suitable values for A & B.

5.Using switch-case statement, write a C program that takes two operands and

one operator from the user, performs the operation and then prints the answer.

(consider operators +,-,/,* and %).

6.Write C procedures to add, subtract, multiply and divide two complex numbers

(x+iy) and (a+ib). Also write the main program that uses these procedures.

7.The total distance traveled by vehicle in ‘t’ seconds is given by distance =

ut+1/2at 2 where ‘u’ and ‘a’ are the initial velocity (m/sec.) and acceleration (m/sec 2). Write C program to find the distance traveled at regular intervals of

time given the values of ‘u’ and ‘a’. The program should provide the flexibility

to the user to select his own time intervals and repeat the calculations for

different values of ‘u’ and ‘a’. 8. A cloth show room has announced the following seasonal discounts onpurchase of items.

Discount (Percentage)

AmountMill ClothHandloom items

1-100-5.0

101-2005.07.5

201-3007.510.0

Above 30010.015.0 PURCHASE

Write a C program using Switch and If statements to complete the net amountto be paid by a customer.

9.Given a number, write a C program using while loop to reverse the digits of thenumber. Example 1234 to be written as 4321.

10.The Fibonacci sequence of numbers is 1,1,2,3,5,8… based on the recurrencerelationf(n) = f (n-1) + f (n-2) for n>2.Write a C program using do-while to calculate and print the first n fibonaccinumbers.

11.Write C programs to print the following outputs using For loop.

122333444455555 122333444455555

12.Write a C program to extract a portion of a character string and print theextracted string. Assume that m characters are extracted starting with the nthcharacter.

13.A Maruthi Car dealer maintains a record of sales of various vehicles in thefollowing form:

Vehicle typeMonth ofSalesPrice (Rs).

Maruthi – 80002/8775,000Maruthi – DX07/8795,000Gypsy04/881,10,000Maruthi Van08/8885,000

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11C:\data\sk\b.tek\b.t.\1.pm5 Write a C program to read this data into a table of strings and output thedetails of a particular vehicle sold during a specified period. The programshould request the user to input the vehicle type and the period (Startingmonth & ending month).

14.Write a function that will scan a character string passed as an argument andcovert all lower case characters into their upper case equivalents.

15.Implement the following data structures using Arrays

i) Stacks ii) Linear Queuesiii) Circular queues

16.Implement binary search tree using linked list and perform the following

operations. i) Insertion ii) Deletion iii) Inorder Traversal iv) Preorder Traversal

v) Post Order Traversal.

17.Singly linked list and doubly linked lists

i) Insertion ii) Deletioniii) Lookup

18.i) Implement stack using singly linked list.ii) Implement queue using singly linked list.

19.Implement the following sorting techniques.i) Bubble sort ii) Insertion Sort iii) Quick Sort iv) Heap Sort.

20.Implement the following searching method. i) Sequential Searchii) Binary Search

21.i) Conversion of Infix expression to Postfix notation.

ii) Simple expression evaluator, that can handle +,-,/ and *.

22.Implement the algorithms for the following iterative methods using C to find

one root of the equation

9x1 +2x2 +4x3 =0 x1 +10x2 +4x3 = 6 2x1 -4x2 +10x3 = -15.

23.Write Computer programs to implement the Lagrange interpolation and Newton-Gregory forward interpolation.

24.Implement in ‘C’ the linear regression and polynomial regression algorithms.

25.Implement Traezoidal and Simpson methods.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

0 3 4

(EE05067) BASIC ELECTRICAL & ELECTRONICS ENGINEERING LAB.

1)Power measurement in 3 phase systems using two-wattmeter method(star connected)

2)Verification of kirchoff’s laws

3)Measurement of choke coil parameters using 3 voltmeter & 3 ammeter method.

4)Magnetization characteristics of a dc shunt machine, determination of criticalfield resistance and critical speed.

5)Open circuit and Shortest Circuit on any 1 phase transformer.

6)Load test on 1-phase transformer.

7)Regulation of 3 phase synchronous generator using OC and SC test.

8)Brake test on 3 phase squirrel cage induction motor.

9)Calibration and testing of single phase energy meter.

10)Calibration of dynamometer type power factor meter.

11)Calibration of PMMC ammeter and voltmeter crompton DC potentio meter.

12)PN junction diode characteristics

a) forward biasb) reverse bias

13)Zener diode characteristics

14)Transistor CE characteristics (Input and Output)

15)Rectifier without filters (Full wave & Half wave)

16)UJT characteristics

17)FET characteristics

18)Study of CRO

19)CE amplifier

20)Class A Amplifier

21)RC Phase shift Oscillator

22)Study of logic gates using ICS.

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

0 3 4

(HS 05232) ENGLISH LANGUAGE COMMUNICA TION SKILLS LAB

The language Lab focuses computer-aided multi-media instruction and languageacquisition to achieve the following targets :

•To expose the students to a variety of self-instructional, learner-friendly modesof language learning.

•To help the students cultivate the habit of reading passages from the computermonitor, thus providing them with the required facility to face computer-basedcompetitive exams such GRE, TOEFL, GMAT etc.

•To enable them to learn better pronunciation through stress on word accent,intonation, and rhythm.

•To train them to use language effectively to face interviews, group discussions,public speaking.

•To initiate them into greater use of the computer in resume preparation,report writing, format-making etc.

However, depending upon the available infrastructure and budget, the abovetargets can also be achieved by procuring the minimum required equipmentsuggested for the establishment of a Conventional Lab the details of whichare given below. The lab should cater to the needs of the students to buildup their confidence to help them develop leadership qualities through theircommunicative competence.

SYLLABUS :

The following course content is prescribed for the English Language LaboratoryPractice :

1.Introduction to Phonetics.

2.Introduction to Vowels and Consonants and associated Phonetic symbols.

3.Introduction to Accent, Intonation and Rhythm.

4.Situational Dialogues / Role Play.

5.Public Speaking.

6.Debate

7.Group discussions

8.Facing Interviews

9.Resume preparation

10.e-correspondence

Minimum Requirement :

•Computer aided multi media language lab with 30 systems with LAN facility.

•Conventional Language Lab. with audio and video systems, speakers, headphones and a teacher console to accommodate 30 students. Suggested Software :•Cambridge Advanced Learners’ Dictionary with exercises

•The Rosetta Stone English Library

•Clarity Pronunciation Power

•Mastering English in Vocabulary, Grammar, Spellings, Composition

•Dorling Kindersley series of Grammar, Punctuation, Composition etc.

•Language in Use, Foundation Books Pvt Ltd

•Learning to Speak English - 4 CDs

•Microsoft Encarta

•Murphy’s English Grammar, Cambridge

•Time series of IQ Test, Brain-teasers, Aptitude Test etc.

•English in Mind, Herbert Puchta and Jeff Stranks with MeredithLevy,Cambridge.

BOOKS SUGGESTED FOR ENGLISH LAB :

1.Developing Communication Skills by Krishna Mohan & Meera Benerji(Macmillan)

2.Speaking English Effectively by Krishna Mohan & NP Singh (Macmillan)

3.Better English Pronunciation by JDO Connor (UBS – Cambridge)

4.Oxford Practice Grammar with Answers, John Eastwood, Oxford

5.Handbook of English Grammar and Usage, Mark Lester and Larry Beason,Tata McGraw-Hill

6.A text book of English Phonetics for Indian Students by T.Balasubramanian(Macmillan)

7.Lingua TOEFL CBT Insider, by Dreamtech

8.TOEFL & GRE( KAPLAN, AARCO & BARRONS, USA, Cracking GRE byCLIFFS)

9.English Skills for Technical Students, WBSCTE with British Council, OL

10.A Handbook of English for Competitive Examinations, by B Shyamala Rao,Blakie Books, Chennai.

DISTRIBUTION AND WEIGHTAGE OF MARKS :

ENGLISH LANGUAGE LABORATORY PRACTICE

1.The practical examinations for the English Language Laboratory practiceshall be conducted as per the University norms prescribed for the coreengineering practical sessions.

2.For the English Language lab sessions, there shall be a continuous evaluationduring the year for 25 sessional marks and 50 End Examination marks. Ofthe 25 marks, 15 marks shall be awarded for day-to-day work and 10 marksto be awarded by conducting Internal Lab Test(s). The End Examinationshall be conducted by the teacher concerned with the help of another memberof the staff of the same department of the same institution.

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

I Year B-TECH B.T.T P C

0 3 4

(ME05220) ENGINEERING DRA WING PRACTICE LAB

Unit –I : Introduction to engineering graphics – construction of ellipse, parabola and

hyperbola – cylindrical curves.

Unit – II : Orthographic projections of points, lines and planes – axis inclined to one

planes and inclined to both the planes.

Unit – III : Orthographic projections of solids : cylinder, cone, prism, pyramid and

sphere positions and axis inclined to both the planes.

Unit – IV: Isomeric projections of lines, planes and simple solids

Unit – V: Conversion of orthographic views into isometric views and vice-versa.

TEXT BOOKS :

1. Engineering graphicsK.L.Narayana & P.Kannayya

2. Engineering drawingsN.D.Bhatt

*_*_*

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. (I Semester)T P C

4+1 0 4

(BT05080) BIOCHEMISTR Y

Unit I: Carbohydrate Structure & Function

Structure and properties of Mono, Di, Oligo & polysaccharides, complex carbohydrates,Confirmation of pyranose & furanose ring, glycosidic bond, Glycogen, starch & dextran;as mobilizable stores of glucose. cellulose, glycoproteins, glycosaminoglycans & lectins;structure and function.

UNIT II: Carbohydrate Metabolism

Glycolysis, Glucogenesis, Glycogenolysis, Gluconeogenesis, ED Pathway, Pentosesphosphate shunt & TCA cycle

UNIT III: Bioenergetics

Respiratory chain, Aerobic and anaerobic respiration; Fermentation.

UNIT IV: Proteins & Amino Acids Metabolism -I

Nitrogen Balance, Amino acids as building blocks of proteins; Protein structure, folding &function, N2 Cycle, reductive amination & transamination &Urea cycle.

UNIT V: Proteins & Amino Acids Metabolism -II

Synthesis of amino acids - Glutamate pathway; Serine pathway; shikimate pathway forthe production of aromatic amino acids.

Unit VI: Lipids & Their Metabolism

Classifications, Structures and roles of fatty acids; fatty acid breakdown; fatty acid synthesis;synthesis and metabolism of triglycerols, cholesterol structure and function. Lipoproteins– classification & function.

UNIT VII: Intermediary Metabolism

Interconnection of pathways & metabolic regulation

UNIT VIII: Photosynthesis

Bacterial & Plant photosynthesis; oxygenic and anoxygenic photosynthesis; chlorophyllas trapper of solar energy, photosynthetic reaction centres, Hill reaction, PS I & PS II,Photophosphorylation - cyclic & non-cyclic; Dark reaction & CO2 fixation.

TEXT BOOKS:

1. Lehninger A.L, Nelson O.’L, M.M. Cox, Principles of Biochemistry, CBS

Publications, 1993. ,

2.Fundamentals of Biochemistry J.L. Jain S. Chand Publishers

REFERENCES:

1.Voet D, Voet J. G, Biochemistry, Second Edition, John C Wiley and Sons,

1994.

2.Stryer L, Biochemistry, Fourth edition, 1994.

3.Biochemistry by K. Mathews, K.E. Van Holde, Kevin G Ahern, Pearson education.

4.Protein’s Structure and function. Daviel Whitford John Wiley Publications.

5.Biochemistry by cristopher K.Mathews, K.E.Van Holde, Pearsons education.

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

4+1 0 4

(BT05079) BIO CHEMICAL THERMODYNAMICS

UNIT I: BASIC CONCEPTS IN ENGINEERING THERMODYNAMICSFirst and Second law of thermodynamics; Calculation of Work, energy and prop-erty changes in reversible processes, Thermodynamics of flow processes; Powercycles and refrigeration cycles

UNIT II: THERMODYNAMIC PROPERTIES OF FLUIDS-IVolumetric properties of gases exhibiting non-ideal behaviour; Residual properties

UNIT III: THERMODYNAMIC PROPERTIES OF FLUIDS-IIEstimation of thermodynamic properties using equations of state; maxwell relation-ships and their applications; Calculation of flow processes based on actual prop-erty changes

UNIT IV: SOLUTION THERMODYNAMICSPartial molar properties; concepts of chemical potential and fugacity Ideal non idealsolutions; Gibbs Duhem equation; Excess properties of mixtures; Activity Coeffi-cient - composition models

UNIT V: PHASE EQUILIBRIACriteria for phase equilibria; Vapour-liquid equilibrium calculations for binary mix-tures, liquid -Liquid equilibria and Solid-liquid equilibria

UNIT VI: CHEMICAL REACTION EQUILIBRIAEquilibrium criteria for homogeneous chemical reactions; Evaluation of equilibriumconstant and effect of pressure and temperature on equilibrium constant; Calcula-tion of equilibrium conversions and yields for single and multiple chemical reac-tions

UNIT VII: BIOCHEMICAL THERM0DYNAMICS-IEnergetics of Metabolic Pathways; Energy Coupling (ATP & NADH); Stoichiometryand energetic analysis of Cell Growth and Product Formation- elemental Balances,Degree of reduction concepts; available -electron balances; yield coefficients;

UNIT VIII: BIOCHEMICAL THERM0DYNAMICS-IIOxygen consumption and heat evolution in aerobic cultures; thermodynamic effi-ciency of growth

TEXT BOOKS :1.J M.Smith,H.C.Van Ness and M.M.Abbott. Introduction to Chemical Engineer-ing Thermodynamics McGraw Hill2.J.A. Roels, Kinetics and Energetics in Biotechnology, Elsevier, 1983

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

4+1 0 4

(BT051 13) CELL BIOLOGY

Unit I: Cell structure and function

Discovery of cells; Basic properties of cells; Cell theory; Cell complexity; Different

classes of cells; Prokaryotic & Eukaryotic system, Prokaryotic & Eukaryotic cells;

Unit II: Chemistry of the cell

Importance of carbon and water; Plasma membrane- structure and function; Cyto-

plasm & Cytoskeleton; Microtubules, microfilaments & intermediate filaments.

Unit III: Intracellular Compartments

Structure and functions of Nucleus, Endoplasmic Reticulum, Golgi Complex, Lyso-

somes, Peroxisomes, Chloroplast & Mitochondria. Protein Glycosylation, Sorting

and Transport.

Unit IV: Transport across Cell Membranes

Passive and Active Transport, Permeases, Na +/K + Pump, ATPase pumps, Lyso-

somal & Vacuolar membrane ATP dependent Proton Pumps, Co-Transport Symport,

Antiport, Transport into Prokaryotic Cells, Endocytosis and Exocytosis.

Unit V: Cell division

Overview of the Cell Cycle, Interphase, Mitosis, Meiosis and Cytokinesis. Animal

Cell & Yeast Cell Division, Cell Cycle Control & Checkpoints.

Unit VI: Cell differentiation

General Characteristics of Cell Differentiation, Historical events in Cell differentia-

tion, Cytoplasmic determinants, Nucleoplasmic Interactions; Stem Cell differentia-

tion and its Biological Importance.

Unit VII: Receptors

Cytosolic, Nuclear & Membrane bound receptors, Examples and types of recep-

tors; Chemo receptors of Bacteria (Attractants & Repellents)

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15C:\data\sk\b.tek\b.t.\1.pm5 Unit VIII: Signal Transduction

Concept of Secondary messengers, cAMP, cGMP, Protein Kinases, G Proteins,

Steroid / Peptide hormone regulation & Tissue specific regulation.

TEXT BOOKS:

1)The Cell by Cooper.

2)Cell and Molecular biology – De Robertis and De Robertis (1998) Waverly

Pvt. Ltd.

References:

1)Cell & Molecular Biology by Gerald Karp (2 nd Ed.) Wiley publishers.

2)The World of the cell by Becker, Reece, Poenie (3 rd edition) Benjamin

Publishers.

3)Molecular Biology of the cell by Bruce Alberts.

4)The biochemistry of Cell Signalling-Ernst J.M.Helmreich. Oxford Press.

5)The world of Cell. 5 th edition- Becker, Kleinsmith, Harden,-Pearson

Publishers.

6)Cell & Molecular Biology by Phillip Sheeler and Donald E.Blanchi 3 rd edition

John Wiley &sons

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

4+1 0 4

(BT05276) GENETICS

Unit I: Physical Basis of HeredityBasic laws of inheritance mono-hybrid, dihybrid and tri-hybrid ratios, Modificationof Mendel’s ratios due to gene interaction. Multiple factors of inheritance. Genesand environment, identification of the genetic materials - classical experiments.Hershey Chase, Avery McLeod etc,

Unit II: Organization of Genetic materialPacking of DNA, organization of genetic material in prokaryotes, Eukaryotes. Eu-chromatin and Heterochromatin organization of Nucleosomes.

Unit III: Linkage & RecombinationChromosomal inheritance, the concept of linkage, cytological basis of crossing over.Mechanism of recombination, Transduction phenomena, Methods of transduction,Generalized, Specialized & Abortive transduction, Bacteriophages - lytic & lysogeniclife cycle Discovery, Detection, Molecular mechanisms of transformation, transfor-mation methods. Bacterial conjugation.

Unit IV: MappingTwo point and three point testcrosses and gene mapping. Mapping of genes bytetrad analysis by mitotic crossing over.

Unit V: Chromosome Structure, Organization & AberrationsChromosome morphology, classification, karyotying. Special chromosome, chro-mosome aberrations, origins, types and cytogenetic effects.

Unit VI: Sex Determination in Prokaryotes and EukaryotesMechanism of sex determination in insect (Fruit fly) and plants (Melandrium), Sexfactors in bacteria, F and HFr transfer, mechanism of transfer.

Unit VII: Sex Determination in HumansSex differentiation and developments in humans, Dosage compensation, Maryleonshypothesis, Sex linked disorders in human beings – Haemophilia, Fragile-x sndrome,Down’s syndrome

Unit VIII: Extra Chromosomal InheritanceIntroduction to extra chromosomal inheritance, examples of extra chromosomalinheritance. Petite phenotypes in yeast. Uniparental inheritance in algae.

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2005-20062005-2006

16C:\data\sk\b.tek\b.t.\1.pm5 TEXT BOOKS1. Principles of Genetics, Gardner EJ, Snustad DP, 20022.Genetics by Strickberger.

REFERENCES:

1. Genetics, Goodenough U, Hold International 19852.Genetics by Griffith.3.Genetics by Brookes.4.Essentials of Genetics (In genomics prospective), Hartwell, 20035.Principles of genetics-Robert H.Tamarin, Tata McGraw Hill.6.Genetics from Genes to Genomes-Leland H.Hartwell, Leroy Hood,Mc Graw Hill.7.Concepts of Genetics- Vii edition-Wiliam S.Klug, Michael R. Cummings.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

4+1 0 4

(BT05402) MICROBIOLOGY

Unit I: Introduction to microbiology1.Discovery of microorganisms; Theory of spontaneous generation, Germ theoryof diseases; Major contribution and events in the field of Microbiology. Scopeand relevance of microbiology.2.Identification of Microorganisms - A general account. Microdiversity

Unit II: Major groups of Microorganisms.1.General characteristics of Bacteria, Archaea and Eubacteria. Diversity classi-fication of Woese et al. Three domains of life. Five - kingdom system ofWhittaker.2.Classification systems - Phylogenetic, Phenetic, Taxonomic ranks, Major char-acteristics used in Taxonomy - Morphological, Physiological, ecological, Bio-chemical, Immunological, Genetical and Molecular.

Unit III: Introduction to VirusesVirus properties, Structure of Viruses; Animal Virology; Plant Virology; Virusesof Arthropods, bacteria and other lower organisms; and classification of vi-ruses (Bacterial, plant and animal replication with 1 example each) and Appli-cations of Virology in Biotech Industry,

Unit IV: Replication of VirusesViral Replication, Bacterial, plant and animal replication with 1 example each( in case of animal viruses the teaching should include the examples of DNAand RNA viral replication and also of those that replicate in the cytoplasm andnucleus).

Unit V: Identification, culturing and Assay of VirusesIdentification and in vitro cultivation of viruses. Assay of viruses ( Both Bacte-rial and animal viruses)

Unit VI: Nutrition, Cultivation and Growth kinetics

1.Nutrition of microorganisms; nutritional classes of microbes, Macro and mi-cronutrients, their sources and physiological functions of nutrients. Growthfactors and their functions in metabolism. Aerobic and anaerobic metabolism.2.Cultivation of microorganisms; Culture media, synthetic, complex media, so-lidifying agents, types of media -selective, differential and enrichment and en-riched media, pure culture methods - spread plate, pour plate and streak plate,special techniques for cultivation of anaerobes.3.Growth of microorganisms, Growth curve, mathematics of growth, measure-

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

4+1 0 4

(BT05559)TRANSPORT PHENOMENA IN BIOPROCESS

UNIT-I : Momentum transfer:Momentum transfer in bioprocess, comparison with other transport processes, effect of flowproperties in momentum transfer and oxygen mass transfer.

UNIT-II: Oxygen transport-IOxygen transport to microbial cultures- Gas liquid mass transfer fundamentals, oxygen re-quirement of microbial cultures. Oxygen requirements of microbial cultures oxygen masstransfer fundamentals. oxygen transfer and oxygen demand.

UNIT-III : Oxygen transport-IIOxygen transfer by aeration and agitation. Determination of oxygen mass transfer coeffi-cient by various methods including dynamic gassing out and oxygen balance methods

UNIT-IV : Momentum transport by agitation:Power requirements and mixing characteristics of ungassed and gassed systems. Conceptof power number, use of monographs. Defining impeller Reynolds number for Newtonianand non-Newtonian fluids. Concept of aeration rate to calculate impeller power requirementof gassed systems.

UNIT-V: MixingMixing and bioreaction interactions – Flow regimes with and without baffles, various types ofimpellers and mixing equipment.

UNIT-VI : Scale-upScale-up criteria for mixing equipment. Application of mixing in bioprocessing.

UNIT-VII : Heat Transfer-IVarious modes of heat transfer, viz., conduction convection and radiation. Mechanism ofheat transfer by conduction, Fourier’s law. Conductive heat transfer through a series ofresistances.

UNIT-VIII : Heat Transfer-IIAnalogy between heat, mass and momentum transfer. Application of heat transfer inbioprocessisng.

TEXT BOOKS :1.Introduction to Biochemical Engineering, D.G.Rao, Tata Mc Hill (2005)2.Bioprocess Engineering Principles Paul M. Doran, Academic press (1995).

REFERENCES1.“Biochemical Engineering fundamentals “2nd edition by J E Bailey and D F Ollis, McGraw-Hill (1986).2.“Biochemical Engineering” by S Aiba, A E Humphrey and N Millis, Prentice- Hall (1978).3.Bio process Engineering : Basic concepts” 2 nd ed., Michaeln L shuler and F Kargi,Prentice Hall of India (2003). ment of microbial growth (cell numbers, cell mass), growth yields and theeffect of limiting factors continuous growth, chemostat, turbidostat, balancedand unbalanced growth.

Unit VII: Identification and Preservation of microbes1.Preservation of Microorganisms; working and primary stock cultures - agarslants, agar stabs, spore preparation, use of sterile soil, cryopreservation,Iyophilisation, Application and limitations of various methods.2.Influence of environmental factors on growth - solutes, water activity, pH, tem-perature, oxygen, osmotic pressure, radiation.3.Colony characteristics, staining techniques; Fixation, Principle dyes, simplestaining, differential staining spore staining, flageller straining.4. Biochemical tests-Sugar fermentations, IMVIC tests, Catalase production etc.

Unit VIII: Control of Microorganisms1.Control of microorganisms, Inhibition of growth and killing, sterilization anddisinfection, physical (moist and dry heat, radiation and filtration), chemicalagents (disinfectants,). Characteristics & mode of action of antimicrobial agent.Classes of disinfectants - phenol and phenolics, alcohol, halogens (CI2 ,Chloramines, Br2 , I2 , tinctures of iodine, iodophores), surfactants (soaps anddetergents) alkylating agents (formaldehyde, glutaraldehyde, [3-propiolac.toneand ethylene oxide) Heavy metals. (Hg, Silver and copper containing com-pounds). Factors affecting sterilization and disinfection. Evaluation of disin-fectants.2.Antimicrobial drugs - History of Chemotherapy, and antibiotics, mode of actionof Antimicrobial drugs (acting on Cell wall, Protein synthesis & Nucleic acids),commonly used Antimicrobial drugs, tests to guide chemotherapy, the effec-tiveness of chemotherapeutic agents.

TEXT BOOKS :1.Microbiology, Pelczar M.J. Chan ECS and Krieg NR. Tata McGraw Hill.2.Introduction to Micro Biology a case History approach 3 rd edition John. L.Ingraham, Catherine A Iingraham. Thomson Publications.

REFERENCES :1.Biology of Micro organisms. BROCK, Prentice Hall, International Inc.2.General Microbiology. Hons. G.Schlege. Combridge University press.3.General Microbiology. Roger Y Stanier, Macmillan.4.General Microbiology. Prescott and Dunn Mc Graw Hill Publishers.5.Introduction to microbiology- A case history approach 3 rd edition- John L.Ingram, Catherine A. Ingram Thomson Publishers

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2005-20062005-2006

18C:\data\sk\b.tek\b.t.\1.pm5

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

0 3 2

(BT05081) BIOCHEMISTR Y LABORA T O R Y

1.Units, Volume & Weight measurements. Concentration units, pH

Measurement. Preparation of buffers,

2.Qualitative tests for carbohydrates. Estimation of Reducing sugars by the

Benedict’s method.

3.Qualitative tests for Amino Acids. Quantitative method for Amino Acids,

Ninhydrin method

4.Protein estimation by Biuret / Folin’s / Bradford method.

5.Extraction of lipids. Saponification of Fats.

6.Estimation of cholesterol.

8.Estimation of Nucleic Acids, Precipitation by sodium sulphate, Test for ribose

and deoxyribose sugar.

9.Extraction of Caffeine from tea leaves.

10.Hydrolysis of ester using Papain.

11.Preparation of

-d Glucopyranose penta acetate from Glucose.`

TEXT BOOK:

1.Laboratory manaual in biochemistry by J.Jayaraman New age InternationalPublications.

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. I-SEMT P C

0 3 2

(BT051 14) CELL BIOLOGY AND MICROBIOLOGY LABORA T O R Y

1.Units, Volume & Weight

1.Calibration of microscope

2.Identification of Animal, Plant & Bacterial cells.

3.Micrometry.

4.Blood cells, WBC differential count.

5.Differential centrifugation and isolation of Chloroplast & Mitochondria.

6.Sterilization techniques (lecture/demonstrations)

7.Preparation of culture media (a) Broth type of media (b) Solid media

8.Culturing of microorganisms: (a) Broth (b) Pure culture techniques: Streak

plate, pour plate.

9.Isolation and preservation of bacterial culture.

10.Identification of microorganisms (a) Staining technique (b) Biochemical

testing.

11.Antibiotic test - Disc diffusion method, minimum inhibitory concentration.

12.Microbiological examination of water.

13.Biochemical tests

IMVIC test

Catalase test

Coagulase test

Gelatinase test

Oxidase test.

14.Determination of bacterial growth by turbidometry / colorimetry.

15.Factors affecting the bacterial growth - effect of Temperature & pH.

TEXT BOOKS:

1.Microbiological and applications, Laboratory, manual in general microbiology

by Benson, Mc Graw Publications.

2.Laboratory manual in microbiology by P. Gunasekharan Newage international

Publishers.

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. II-SEMT P C

4+1 0 4

(BT05096) BIOPROCESS ENGINEERING

Unit I: Introduction to Bioprocesses

Historical development of bioprocess technology, an overview of traditional and

modern applications of biotechnology industry, outline of an integrated bioprocess

and the various (upstream and down stream) unit operations involved in

bioprocesses, generalized process flow sheets.

Unit II: Fermentation Processes-I

General requirements of fermentation processes, Basic design and construction of

fermentor and ancillaries, Main parameters to be monitored and controlled in

fermentation processes;

Unit III: Fermentation Processes-II

An overview of aerobic and anaerobic fermentation processes and their application

in the biotechnology industry, solid-substrate, slurry fermentation and its applications,

whole cell immobilization, behaviour of microbes in different reactors (air lift, fluidized,

batch, continuous fed batch condition).

Unit IV: Media Design

Medium requirements for fermentation processes, Carbon, nitrogen, minerals,

vitamins and other complex nutrients, oxygen requirements, medium formulation

for optimal growth and product formation, examples of simple and complex media,

design and usage of various commercial media for industrial fermentations

Unit V: Sterilization

Thermal death kinetics of microorganisms, batch and continuous heat. Sterilization

of liquid media, filter sterilization of liquid media, Air. Design of sterilization equipment. Unit VI: Metabolic StoichiometryStoichiometry of Cell growth and product formation, elemental balances, degreesof reduction of substrate and biomass, available electron balances, yield coefficients

of biomass and product formation, maintenance coefficients.

Unit VII: Energetics

Energetic analysis of microbial growth and product formation, oxygen consumption

and heat evolution in aerobic cultures, thermodynamic efficiency of growth.

Unit VIII: Kinetics Of Microbial Growth And Product Formation

Phases of cell growth in batch cultures, Simple unstructured kinetic models for

microbial growth, Monod model, Growth of filamentous organisms. Growth

associated (primary) and non - growth associated (secondary) product formation

Kinetics. Leudeking-Piret models, substrate and product inhibition on cell growth

and product formation. Introduction to Structured Models for growth and product

formation.

TEXT BOOKS

1.Biochemical Engineering Fundamentals Bailey and Ollis, McGraw Hill (2 nd

Ed.), 1986.

2.Bioprocess Engineering, Shule and Kargi, Prentice Hall, 1992.

REFERENCE:

1.Stanbury, P. F., Whitaker, A., & Hall, S. J., (1998), Principles of fermentation

Technology, 2 nd ed., Elsevier Science Publishers, BV, Amsterdam.

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. II-SEMT P C

4+1 0 4

(CE 05239) ENVIRONMENT AL STUDIES

UNIT - I

Multidisciplinary nature of Environmental Studies: Definition, Scope andImportance – Need for Public Awareness.

UNIT - II

Natural Resources : Renewable and non-renewable resources – Natural resourcesand associated problems – Forest resources – Use and over – exploitation,deforestation, case studies – Timber extraction – Mining, dams and other effects onforest and tribal people – Water resources – Use and over utilization of surface andground water – Floods, drought, conflicts over water, dams – benefits and problems- Mineral resources: Use and exploitation, environmental effects of extracting andusing mineral resources, case studies. - Food resources: World food problems,changes caused by agriculture and overgrazing, effects of modern agriculture,fertilizer-pesticide problems, water logging, salinity, case studies. - Energy resources:Growing energy needs, renewable and non-renewable energy sources use ofalternate energy sources. Case studies. Land resources: Land as a resource, landdegradation, man induced landslides, soil erosion and desertification. Role of anindividual in conservation of natural resources. Equitable use of resources forsustainable lifestyles.

UNIT - III

Ecosystems : Concept of an ecosystem. - Structure and function of an ecosystem.- Producers, consumers and decomposers. - Energy flow in the ecosystem -Ecological succession. - Food chains, food webs and ecological pyramids. -Introduction, types, characteristic features, structure and function of the followingecosystem:

a. Forest ecosystem

b. Grassland ecosystem

c. Desert ecosystem

d. Aquatic ecosystems (ponds, streams, lakes, rivers, oceans, estuaries)

UNIT - IV

Biodiversity and its conservation : Introduction - Definition: genetic, species andecosystem diversity. - Bio-geographical classification of India - Value of biodiversity:consumptive use, productive use, social, ethical, aesthetic and option values - .Biodiversity at global, National and local levels. - . India as a mega-diversity nation- Hot-sports of biodiversity - Threats to biodiversity: habitat loss, poaching of wildlife,man-wildlife conflicts. - Endangered and endemic species of India - Conservationof biodiversity: In-situ and Ex-situ conservation of biodiversity. UNIT - VEnvironmental Pollution : Definition, Cause, effects and control measures of :

a.Air pollution

b.Water pollution

c.Soil pollution

d.Marine pollution

e.Noise pollution

f.Thermal pollution

g.Nuclear hazards

Solid waste Management : Causes, effects and control measures of urban andindustrial wastes. - Role of an individual in prevention of pollution. - Pollution casestudies. - Disaster management: floods, earthquake, cyclone and landslides.

UNIT - VI

Social Issues and the Environment : From Unsustainable to Sustainabledevelopment -Urban problems related to energy -Water conservation, rain waterharvesting, watershed management -Resettlement and rehabilitation of people; itsproblems and concerns. Case Studies -Environmental ethics: Issues and possiblesolutions. -Climate change, global warming, acid rain, ozone layer depletion, nuclearaccidents and holocaust. Case Studies. -Wasteland reclamation. -Consumerismand waste products. -Environment Protection Act. -Air (Prevention and Control ofPollution) Act. -Water (Prevention and control of Pollution) Act -Wildlife ProtectionAct -Forest Conservation Act -Issues involved in enforcement of environmentallegislation. -Public awareness.

UNIT - VII

Human Population and the Environment : Population growth, variation amongnations. Population explosion - Family Welfare Programme. -Environment andhuman health. -Human Rights. -Value Education. -HIV/AIDS. -Women and ChildWelfare. -Role of information Technology in Environment and human health. -CaseStudies.

UNIT - VIII

Field work : Visit to a local area to document environmental assets River /forestgrassland/hill/mountain -Visit to a local polluted site-Urban/Rural/industrial/Agricultural Study of common plants, insects, birds. -Study of simple ecosystems-pond, river, hill slopes, etc.

TEXT BOOK:

1.Textbook of Environmental Studies for Undergraduate Courses by ErachBharucha for University Grants Commission.

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2005-20062005-2006

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J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD

II Year B-TECH B.T. II-SEMT P C

4+1 0 4

(BT05319) INSTRUMENT AL METHODS OF ANAL YSIS

Unit I: IntroductionTypes of Analytical Methods – Instruments for Analysis – Uncertainties inInstrumental measurements – Sensitivity and detection limit for instruments.

Unit II: MicroscopyBright field, Dark field, Fluorescent, Phase contrast, confocal microscopy, SEM &TEM Microscopy, Flow Cytometry.

Unit IV: Spectroscopy-IGeneral principles – Radiation, energy and atomic structure- types of spectra andtheir biochemical usefulness – basic laws of light absorption. Electromagneticradiation & Spectrum, Beer – Lambert’s Law and apparent deviations; UV - VISSpectrophotometer,Unit V: Spectroscopy-IISpectrofluorimetry, Atomic absorption & Atomic emission spectroscopy, CirularDichroism (CD)- principles, instrumentation and applications.

Unit VI: Spectroscopy-IIIInfra Red Spectroscopy. Mass spectroscopy-Introduction, analysis, applications inbiology

Unit VII: NMRHigh resolution NMR –Chemical shift-Spin-spin coupling Frequency lock- doubleresonance-applications of proton NMR-quantitative analysis-qualitative analysis,application of NMR in biology and study of macromolecules

Unit VIII: SpectroscopyESR principles - instrumentation-applications

TEXT BOOKS:1.A Biologist Guide to principles and techniques of practical Biochemistry. ByKeith Wilson, Kenneth H. Goulding 3 rd ed. ELBS Series.2.Skoog & West, Fundamentals of Analytical Chemistry, 1982

REFERENCES:1.Vogel, Text Book of Quantitative Inorganic Analysis, 19902.Ewing, Instrumental Methods of Analysis, 19923.Hobert H Willard D. L. Merritt & J. R. J. A. Dean, Instrumental Methods ofAnalysis, CBS Publishers & Distributors, 1992

J A W AHARLAL NEHRU TECHNOLOGICAL UNIVERSITY

HYDERABAD.

II Year B.Tech. BT - II SemesterT P C

4+1 0 4

(HS05353)MANAGERIAL ECONOMICS AND FINANCIAL ANAL YSIS

UNIT I

INTRODUCTION TO MANAGERIAL ECONOMICS

Definition, Nature and Scope Managerial Economics–Demand Analysis: Demand

Determinants, Law of Demand and its exceptions.

UNIT II

ELASTICITY OF DEMAND

Definition, Types, Measurement and Significance of Elasticity of Demand. Demand

Forecasting, Factors governing demand forecasting, methods of demand forecast-

ing (survey methods, statistical methods, expert opinion method, test marketing,

controlled experiments, judgmental approach to demand forecasting)

UNIT III

THEORY OF PRODUCTION AND COST ANALYSIS

Production Function – Isoquants and Isocosts, MRTS, Least Cost Combination of

Inputs, Production function, Laws of Returns, Internal and External Economies of

Scale.

Cost Analysis: Cost concepts, Opportunity cost, Fixed Vs.Variable costs, Explicit

costs Vs.Implicit costs, Out of pocket costs vs. Imputed costs. Break-even Analysis

(BEA)-termination of Break-Even Point (simple problems)-Managerial Significance

and limitations of BEA.

UNIT IV

INTRODUCTION TO MARKETS & PRICING STRATEGIES

Market structures: Types of competition, Features of Perfect competition, Monopoly

and Monopolistic Competition. Price-Output Determination in case of Perfect Com-

petition and Monopoly. Pricing Strategies

UNIT V

BUSINESS & NEW ECONOMIC ENVIRONMENT

Characteristic features of Business, Features and evaluation of Sole Proprietor-

ship, Partnership, Joint Stock Company, Public Enterprises and their types, Changing

Business Environment in Post-liberalization scenario.

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