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Title: Report of therapeutic effects of Granulocyte colony- stimulating factor in a patient with second and third- degree burns, having leukopenia and sepsis
Authors: L. Mohajerzadeh1, M .Khatami2, MH. Amouzegar3 Abstract
Bacterial infection following major burn injury leads to neutrophile dysfunction and neutropenia which results in serious sepsis. Administration of graolocyte-colon specific factor (G-CSF) is useful for treatment of neutropenia and decreasing the complications of severe infection following burn injuries. A 2- year old boy with major burn injury, despite administration of broad spectrum antibiotics, became neutropenic followed by serious sepsis. After administration of G-CSF, neutropenia was resolved. Finally, after surgical debridement and skin graft, the patient recovered and discharged.
Key Words: Graolocyte-colon specific factor; Neutropenia; Burn; Sepsis
1Corresponding Author; General Surgeon, Department of Plastic and Reconstructive Surgery/ Burns Centre, Imam Reza Hospital, Mashhad, Iran [email protected]
2Pediatrician, Department of Pediatrics, Imam Reza Hospital, Mashhad, Iran
3 Assistant Professor, Department of Plastic and Reconstructive Surgery/ Burns Centre, Imam Reza Hospital, Mashhad, Iran
