:ﻪﺒﺗﺎﮑﻣ سردآ*
،ﺮﯾﺪﻐﻟا راﻮﻠﺑ ،ﻢﻗ ﻢﻗ هﺎﮕﺸﻧاد
.
ﺖﺴﭘ :ﮏﯿﻧوﺮﺘﮑﻟا [email protected]
،نژﻮﻨﯾﺮﺒﯿﻓ ﯽﻣﺮﺳ حﻮﻄﺳ ﺮﺑ ﺖﻣﺎﺠﺣ و يزاﻮﻫ ﻦﯾﺮﻤﺗ هﻮﯿﺷ ود ﻪﺴﯾﺎﻘﻣ و
LDLيﺎﻫرﻮﺘﮐﺎﻓ ناﻮﻨﻋ ﻪﺑ
HDLﻪﺴﺋﺎﯾ نﺎﻧز ﯽﻗوﺮﻋ و ﯽﺒﻠﻗ يﺎﻫ يرﺎﻤﯿﺑ
دﺎﺸﻟد ﺮﯿﻣا
1
ﺘﺷد تادﺎﺳ ﻢﯾﺮﻣ ،
*ﯽ ﺮﺒﮐا ﺪﯿﻌﺳ ،
2ي ﭽﯾﻮﻠﻋ يﺰﯾﺰﻋ اﺮﻫز ،
2ﻪ
2
1 -
،ﯽﺷزرو مﻮﻠﻋ هوﺮﮔ ،رﺎﯾدﺎﺘﺳا ﻋ و تﺎﯿﺑدا هﺪﮑﺸﻧاد
،ﻢﻗ ،ﻢﻗ هﺎﮕﺸﻧاد ﯽﻧﺎﺴﻧا مﻮﻠ ناﺮﯾا
2 - شزرو يژﻮﻟﻮﯾﺰﯿﻓ ﺪﺷرا ﯽﺳﺎﻨﺷرﺎﮐ ،
ﻮﻠﻋ هوﺮﮔ م
،ﯽﺷزرو ﯽﻧﺎﺴﻧا مﻮﻠﻋ و تﺎﯿﺑدا هﺪﮑﺸﻧاد
،ﻢﻗ ،ﻢﻗ هﺎﮕﺸﻧاد ناﺮﯾا
هرود / ﻪﺘﻓﺎﯾ 24
هرﺎﻤﺷ / 1
رﺎﻬﺑ / 1401
/ ﻞﺴﻠﺴﻣ 91
:ﻪﻟﺎﻘﻣ ﺖﻓﺎﯾرد 29
/1 / 1401 :ﻪﻟﺎﻘﻣ شﺮﯾﺬﭘ 21
/ 2 / 1401
ﻪﻣﺪﻘﻣ :
ﯾ ﮕﺴﺋﺎ ﯽ ﯾ ﮏ ﻧﺎﻣز هرود ﯽ ﻟﺎﺑ ﯿﻨ ﯽ ﻐﺗ ﺎﺑ ﻪﮐ ﺖﺳا ﻢﻬﻣ ﯿﯿ
تاﺮ رﻮﻫ نﻮﻣ اﺰﻓا و رﻮﺗﻮﻣوزاو ﻢﺋﻼﻋ ،ناﺪﻤﺨﺗ ﯾ
ﺶ ﺑ ﺮﻄﺧ ﯿ رﺎﻤ ي ﺎﻫ ي ﻗ ﺒﻠ ﯽ ﻗوﺮﻋ ﯽ (CVD)
ﻣ ﺺﺨﺸﻣ ﻮﺸﯿ ﯽﮑﯾ .د زا ﯽﻠﺻا ﻞﻠﻋ ﻪﻠﻤﺣ يﺎﻫ ﯽﺒﻠﻗ تاﺮﯿﯿﻐﺗ و مﺪﻋ لدﺎﻌﺗ ﻢﺘﺴﯿﺳ ﯽﮐﺮﺤﺗ ﻢﮐ .ﺖﺳا زﺎﺘﺳﻮﻤﻫ ﺶﯾاﺰﻓا و
ﻦﺳ ﺰﯿﻧ تاﺮﯿﺛﺄﺗ ﻧ ﯽﺒﺳﺎﻨﻣﺎ
ﻢﺘﺴﯿﺳﺮﺑ زﺎﺘﺳﻮﻤﻫ .ﺪﻧراد لﺎﺳ ﻪﮐ ﯽﻧﺎﻣرد يﺎﻫ شور زا ﯽﮑﯾ ﺐﻃ ،ﺖﺳا ﻪﺘﺷاد دﺮﺑرﺎﮐ ﺎﻫ يرﺎﻤﯿﺑ زا يرﺎﯿﺴﺑ نﺎﻣرد رد ﺎﻫ
ﯽﻧاﺮﯾا - ﯽﻣﻼﺳا ﯽﻣ ﺪﺷﺎﺑ .
ﯾا رد ﻦﯾاﺮﺑﺎﻨﺑ ناﺰﯿﻣ ﺮﺑ يزاﻮﻫ تﺎﻨﯾﺮﻤﺗ و ﺖﻣﺎﺠﺣ ﺮﺛا ﻪﻌﻟﺎﻄﻣ ﻦ
LDL , HDL .ﺖﻓﺮﮔ راﺮﻗ ﯽﺳرﺮﺑ درﻮﻣ نژﻮﻨﯾﺮﺒﯿﻓ و
شور و داﻮﻣ :ﺎﻫ
ﯽﺑﺮﺠﺗ ﻪﻤﯿﻧ ﺶﻫوﮋﭘ ﻦﯾا رد 30
نز ﯽﻨﺳ ﻪﻨﻣاد ﺎﺑ لﺎﻌﻓﺮﯿﻏ ﻪﺴﺋﺎﯾ 55
ﺎﺗ 65 ﺪﻧدﺮﮐ ﺖﮐﺮﺷ ﺒﻠﻃواد .
ﯿ ﻦ ﺗ ترﻮﺻ ﻪﺑ ﻓدﺎﺼ ﯽ ﻪﺑ ﻪﺳ هوﺮﮔ
ﺮﻤﺗ ﯾ ﻦ زاﻮﻫ ي
، و ﺖﻣﺎﺠﺣ هوﺮﮔ لﺮﺘﻨﮐ ﺴﻘﺗ ﯿ ﻢ ﺷ ﺪ ﺪﻧ . تﺪﺷ ﺎﺑ يزاﻮﻫ تﺎﻨﯾﺮﻤﺗ 50
ﺎﺗ 75 ﻪﺘﻔﻫ هﺮﯿﺧذ ﺐﻠﻗ نﺎﺑﺮﺿ ﺪﺻرد ﯽﻃ رد و ﻪﺴﻠﺟ ﻪﺳ يا
6 ﻪﺘﻔﻫ
ﺪﻧﺪﺷ ﺖﻣﺎﺠﺣ ﻢﺠﻨﭘ و مود ﻪﺘﻔﻫ رد رﺎﺑود ﺖﻣﺎﺠﺣ هوﺮﮔ و ﺪﺷ اﺮﺟا .
و ﯽﻨﯾﺮﻤﺗ هرود عوﺮﺷ زا ﻞﺒﻗ 48
ﻪﺴﻠﺟ ﻦﯾﺮﺧآ مﺎﻤﺗا زا ﺲﭘ ﺖﻋﺎﺳ يﺮﯿﮕﻧﻮﺧ ﻦﯾﺮﻤﺗ
هزاﺪﻧا ﺖﻬﺟ ﺺﺧﺎﺷ يﺮﯿﮔ
،نژﻮﻨﯾﺮﺒﯿﻓ يﺎﻫ LDL, HDL
زآزا هدﺎﻔﺘﺳا ﺎﺑ ﺲﭙﺳ .ﺖﻓﺮﮔ مﺎﺠﻧا ﺲﻧﺎﯾراوﻮﮐ ﺰﯿﻟﺎﻧآ نﻮﻣ
ﻪﺴﯾﺎﻘﻣ و ﯽﻫوﺮﮔ ﻦﯿﺑ ﻪﺴﯾﺎﻘﻣ ياﺮﺑ
ﺶﯿﭘ ﺲﭘ و نﻮﻣزآ هوﺮﮔ ﻦﯿﺑ نﻮﻣزآ
نﻮﻣزآ زا ﺎﻫ ﺢﻄﺳرد ﯽﺟوزt
يرادﺎﻨﻌﻣ 0.05 a<
ﺖﻓﺮﮔ ترﻮﺻ ﻞﯿﻠﺤﺗ
.
ﻪﺘﻓﺎﯾ :ﺎﻫ
ﯽﻨﻌﻣ ﺶﻫﺎﮐ ﺖﻣﺎﺠﺣ و يزاﻮﻫ ﻦﯾﺮﻤﺗ ) نژﻮﻨﯾﺮﺒﯿﻓ راد
04 /0 و (P=
)LDL 001 /0 ( P=
ﺶﯾاﺰﻓا و )LDH 003 /0 .ﺪﻧداد نﺎﺸﻧ (P=
نﻮﻣزآ ﺞﯾﺎﺘﻧ
ـﻨﻌﻣ ﺶﻫﺎـﮐ زا ﯽﮐﺎـﺣ ﯽـﺟوزT ﺎ
راد
،نژﻮﻨﯾﺮﺒﯿﻓ وLDL
دﻮﺑ ﻪﻠﺧاﺪﻣ زا ﺲﭘ نﻮﻣزآ ﺶﯿﭘ ﻪﺑ ﺖﺒﺴﻧ نﻮﻣزآ ﺲﭘHDL .
ﻪﺠﯿﺘﻧ و ﺚﺤﺑ :يﺮﯿﮔ
و نژﻮﻨﯾﺮﺒﯿﻓ ﺢﻄﺳ راد ﯽﻨﻌﻣ ﺶﻫﺎﮐ ﺮﺑ ﺮﺛﻮﻣ ﯽﻠﻣاﻮﻋ يزاﻮﻫ ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ و ﺖﻣﺎﺠﺣ ﻓا و نژﻮﻨﯾﺮﺒﯿﻓ وLDL
ﺶﯾاﺰ رد ﺮﺑHDL
ﮐ ﯽﻧﻮﺧ يﺎﻫ ﺪﯿﭙﯿﻟ و نژﻮﻨﯾﺮﺒﯿﻓ ﺮﺑ يﺮﺘﻬﺑ رﺎﺛآ ﺖﻣﺎﺠﺣ ﻪﺑ ﺖﺒﺴﻧ ﺪﻧاﻮﺘﯿﻣ شزرو ﻻﺎﻤﺘﺣا ﺞﯾﺎﺘﻧ ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ .ﺪﺷﺎﺑ ﯽﻣ ﻪﺴﺋﺎﯾ نﺎﻧز ﻤﺟ زا ﻪ
ﻋ ﻦﯾﺮﺘﻤﻬﻣ ﻪﻠ ﻞﻣاﻮ
ﯽﺒﻠﻗ يرﺎﻤﯿﺑ ياز ﺮﻄﺧ -
ﻋ .ﺪﺷﺎﺑ ﻪﺘﺷاد ،ﺖﺳا ﻦﯿﯾاﺮﺷ ﺐﻠﺼﺗ و ﯽﻗوﺮ
هژاو ﺪﯿﻠﮐ يﺎﻫ :ي
،يزاﻮﻫ ﻦﯾﺮﻤﺗ ،ﺖﻣﺎﺠﺣ ،LDL
DH نژﻮﻨﯾﺮﺒﯿﻓ ،L
.
هﺪﯿﮑﭼ
ﻪﻣﺪﻘﻣ
ﯾ ﮕـﺴﺋﺎ ﯽ ــﯾ ﮏ ﻧﺎـﻣز هرود ﯽ
ﻟﺎــﺑ ﯿﻨ ﯽ ﺎــﺑ ﻪـﮐ ﺖــﺳا ﻢـﻬﻣ
ﻐﺗ ﯿﯿ تاﺮ رﻮﻫ نﻮﻣ اﺰﻓا و رﻮﺗﻮﻣوزاو ﻢﺋﻼﻋ ،ناﺪﻤﺨﺗ ﯾ
ﺶ ﺮﻄﺧ
ﺑﯿ رﺎﻤ ي ﺎﻫ ي ﺒﻠﻗ ﯽ ﻗوﺮﻋ ﯽ (CVD) ﻣ ﺺﺨﺸﻣ ﯽ
دﻮﺷ ) 1 .(
ﻠﺒﻗ تﺎﻌﻟﺎﻄﻣ ﯽ
ﻣ نﺎﺸﻧ ﯽ زا ﺪـﻌﺑ نﺎـﻧز ﻪﮐ ﺪﻫد ﯾ
ﮕـﺴﺋﺎ ﯽ رد
ﺎﻘﻣ ﯾ ﻪﺴ زا ﻞـﺒﻗ نﺎﻧز ﺎﺑ ﯾ
ﮕـﺴﺋﺎ ﯽ ﺑﯿ ﺮﺘـﺸ ضﺮـﻌﻣ رد ﺮـﻄﺧ
) ﺪﻨﺘﺴﻫ (CVD )
2 ﯽﮑﯾ .(
زا ﯽﻠﺻا ﻞﻠﻋ ﻪﻠﻤﺣ
يﺎﻫ ﯽـﺒﻠﻗ
تاﺮﯿﯿﻐﺗ و مﺪﻋ لدﺎﻌﺗ ﻢﺘﺴﯿﺳ ﺖﺳا زﺎﺘﺳﻮﻤﻫ ﻪﮐ
ﯽﻣ ﺪـﻧاﻮﺗ
ﺮﺠﻨﻣ ﻪﺑ زﻮﺒﻣوﺮﺗ و ﻪﻠﻤﺣ يﺎـﻫ ﯽـﺒﻠﻗ دﻮـﺷ ﺰﯿﻟﻮـﻨﯾﺮﺒﯿﻓ. و
دﺎــﻘﻌﻧا ود وﺰــﺟ ﯽﻠــﺻا ﺪــﻨﯾاﺮﻓ زﺎﺘــﺳﻮﻤﻫ ﺪﻨﺘــﺴﻫ
ﻞــﻣاﻮﻋ.
يرﺎﯿﺴﺑ زا ﻪﻠﻤﺟ
،ﻦﺳ
،ﺲﻨﺟ
،ﯽﮕﺴﺋﺎﯾ شزرو و ﻢﯾژر ﯽﺘﺣ
ﯽﯾاﺬﻏ ﺮﺑ ا ياﺰﺟ ﻢﺘﺴﯿﺳ ﻦﯾا ﺮﯿﺛﺄﺗ
ﯽﻣ ﺪﻧراﺬﮔ ) 3 .(
نژﻮﻨﯾﺮﺒﯿﻓ ﻪﺑ
ﮏﯾ ناﻮﻨﻋ ياﺮﺘﺴﺑﻮﺳ
ﻢﯿﻘﺘﺴﻣ
،ﻪـﺘﺨﻟ
ﺎــﺑ دﺎــﺠﯾا ﻞﭘ يﺎــﻫ ﯽﻟﺎــﺼﺗا ﻦﯿــﺑ ﺖــﮐﻼﭘ ﺎــﻫ ﺶﯾاﺰــﻓا و
،ﻪﺘﯾزﻮﮑﺴﯾو ﯽﻣ
ﺪﻧاﻮﺗ ﺮﻄﺧ ﻪﺘﺨﻟ ﯽﯾاز ار ﺶﯾاﺰﻓا ﺪـﻫد
) 4 نﺎﻧز .(
ﻪﺴﺋﺎﯾ ياراد ﺢﻄﺳ ﺮﺗﻻﺎﺑ نژﻮﻨﯾﺮﺒﯿﻓ و
ترﺪـﻗ
ﺰﯿﻟﻮﻨﯾﺮﺒﯿﻓ ﻦﯿﯾﺎﭘ
يﺮﺗ ﺖﺒﺴﻧ ﻪﺑ ﻧﺎﺑ ناﻮ ﻪﺴﺋﺎﯾ ﺮﯿﻏ ﻨﺘﺴﻫ
ﺪ
ﻪﮐ ﯽﻣ ﺪﻧاﻮﺗ ﯽﺤﯿﺿﻮﺗ ياﺮﺑ
ﺶﯾاﺰـﻓا ﺮـﻄﺧ رﺎـﻤﯿﺑ يﺎـﻬﯾ
ﯽﺒﻠﻗ - ﯽﻗوﺮﻋ ﺪﺷﺎﺑ ) 5 ﻦﯿﻨﭽﻤﻫ .(
اﺰﻓا ﯾ ﺶ ﺮـﻄﺧ CVD
ﺪﺣ ﺎﺗ ﺖﺳا ﻦﮑﻤﻣ ي
ﺷﺎﻧ ﯽ ﻐﺗ زا ﯿﯿ تاﺮ ﺎﻓوﺮﭘ رد ﺮﻀﻣ ـﯾ
ﻞ
ﺎﻫ ي ﻟ ﯿﭙ ﯿ ﺪ ﯾ ﺎ ﻟ ﯿ ﺌﺗوﺮﭘﻮﭙ ﯿ ﻦ ﺎـﺑ ﻪﮐ ﺪﺷﺎﺑ ﯾ
ﮕـﺴﺋﺎ ﯽ ﻂﺒﺗﺮـﻣ
ﻨﺘﺴﻫ ﺪ ) 2 .(
ﭘا تﺎﻌﻟﺎﻄﻣ ﯿ
ﻣﺪ ﯿ ژﻮﻟﻮ ﯽﯾ ﻣ ﯿ ناﺰ مﺎﺗ لوﺮﺘﺴﻠﮐ
) ﻟ ،(TC ﯿ ﺌﺗوﺮﭘﻮﭙ ﯿ ﻦ ) لﺎـﮕﭼ ﻢـﮐ لوﺮﺘﺴﻠﮐ LDL-C
( ،
ﺮﺗ ي ﻠﮔ ﯿ ﺴ ﯿﺮ ﯾﺪ ) زا ﺪﻌﺑ رد ار (TG ﯾ
ﮕﺴﺋﺎ ﯽ ﺎﻘﻣ رد ﯾ ﻪﺴ ﺎﺑ
زا ﻞﺒﻗ نﺎﻧز ﯾ
ﮕﺴﺋﺎ ﯽ ﺎـﺘﻧ .داد نﺎـﺸﻧ ﯾ
ﺞ ﯽـﻀﻗﺎﻨﺘﻣ اﺮـﺑ
ي
)HDL HDL-C (
ﭘﯿ اﺪ ﺪﺷ ) 1 .(
د تﺎﻌﻟﺎﻄﻣ ﯾ
ﺮﮕ هرود ﻪـﮐ ﺪـﻧدﺮﮐ شراﺰﮔ ﯾ
ﮕـﺴﺋﺎ ﯽ ﺎـﺑ
اﺰـﻓا ﯾ ﺶ
،مﺎـﺗ لوﺮﺘـﺴﻠﮐ LDL-C
، و دﻮـﺑ هاﺮـﻤﻫTG
ﺑﯿ ﺘﺸ ﺮﯾ ﻦ اﺰـﻓا ﯾ ﺶ ﺢﻄـﺳ رد
HDL-C هرود ﺮـﺧاوا رد
ﯾ ﮕﺴﺋﺎ ﯽ اوا و ـﯾ ﻞ زا ﺲـﭘ ﯾ ﮕـﺴﺋﺎ ﯽ ﺪـﺷ هﺪﻫﺎـﺸﻣ )
6،7 .(
زا ﯽـﮑﯾ ﻪـﮐ ﺖـﺳا هداد نﺎـﺸﻧ ﮏﯾژﻮﻟﻮﯿﻣﺪـﯿﭘا تﺎﻌﻟﺎﻄﻣ ﺎـﺑ ﻦﯿﺌﺗوﺮﭘﻮـﭙﯿﻟ ،ﺎـﻫ يرﺎـﻤﯿﺑ ﻦـﯾا ﯽﺳﺎﺳا ﺮﻄﺧ ﻞﻣاﻮﻋ ) ﻻﺎـﺑ ﯽﻟﺎﮕﭼ
ﯽﻣ (HDL ﺶﻫﺎـﮐ ﻪـﮐ يرﻮـﻃ ﻪـﺑ ؛ﺪـﺷﺎﺑ
ﺢﻄﺳ ﺗرا ﺎـﻫ يرﺎـﻤﯿﺑ ﻦـﯾا ﺮـﻄﺧ ﺶﯾاﺰﻓا ﺎﺑHDL
طﺎـﺒ
ﯽﻟﺎـﮕﭼ ﺎـﺑ ﻦﯿﺌﺗوﺮﭘﻮﭙﯿﻟ لوﺮﺘﺴﻠﮐ ﺖﻈﻠﻏ .دراد ﻢﯿﻘﺘﺴﻣ ﺪﺿ ﯽﻨﯿﺌﺗوﺮﭘﻮﭙﯿﻟ تارذ ناﻮﻨﻋ ﻪﺑ هزوﺮﻣا ،ﺎﻤﺳﻼﭘ رد ﻻﺎﺑ ﯽـﺒﻠﻗ يرﺎـﻤﯿﺑ ﺎﺑ و ﺖﺳا هﺪﺷ حﺮﻄﻣ ﮏﯿﻧژوﺮﺗا -
ﯽـﻗوﺮﻋ
هاﺮـﻤﻫ يﺮـﻧوﺮﮐ قوﺮﻋ يرﺎﻤﯿﺑ هﮋﯾو ﻪﺑ ،ﮏﯿﺗوﺮﻠﮑﺳاوﺮﺗا ﺖــﺳا ) 8 ﻪــﻄﺑار هﺪــﺷ مﺎــﺠﻧا تﺎــﻌﻟﺎﻄﻣ رد ﻦﯿــﻨﭽﻤﻫ .(
ﺘــﺴﻠﮐ نﺎــﯿﻣ ﯽــﮑﯾدﺰﻧ لوﺮ
و داﺮــﻓا مﺮــﺳ رد ﻻﺎــﺑLDL
زوﺮﻠﮑــﺳاوﺮﺗا عاﻮــﻧا ﺮﯾﺎــﺳ و ﯽــﺒﻠﻗﺮﻧوﺮﮐ قوﺮــﻋ يرﺎــﻤﯿﺑ لﺎﻣﺮﻧ لوﺮﺘﺴﻠﮐ ﻪﮐ يدراﻮﻣ رد ﯽﺘﺣ .ﺖﺳا هﺪﺷ هﺪﻫﺎﺸﻣ ندﻮـﺑ ﻻﺎـﺑ ﺰﯿﻧ ﺪﺷﺎﺑ ﮏـﺴﯾر ندﻮـﺑ ﻻﺎـﺑ ﺮﮕﻧﺎـﺸﻧLDL
يرﺎﻤﯿﺑ ﺖﺳا زوﺮﻠﮑﺳاوﺮﺗا و يﺮﻧوﺮﮐ قوﺮﻋ يﺎﻫ )
9 ﻢـﮐ .(
ﯽﮐﺮﺤﺗ ﺶﯾاﺰﻓا و ﻦﺳ
ﺰﯿﻧ تاﺮﯿﺛﺄﺗ ﯽﺒـﺳﺎﻨﻣﺎﻧ ﺑ
ﻢﺘـﺴﯿﺳﺮ
زﺎﺘﺳﻮﻤﻫ ﺪﻧراد
) 5 .(
رد ﺖﮐﺮـﺷ ﻪـﺑ ﻞـﯿﻣ ﻪﺴﺋﺎﯾ نﺎﻧز رد
ًﻻﻮـﻤﻌﻣ و ﺖـﺳا ﻢـﮐ ﯽـﺷزرو و ﯽﻧﺪـﺑ يﺎﻫ ﺖﯿﻟﺎﻌﻓ ﻢـﮐ
و ﯽﮐﺮﺤﺗ يﺎـﻫ يرﺎـﻤﯿﺑ زوﺮـﺑ ﻪـﻨﯿﻣز ﯽﺘﮐﺮﺣ ﯽﺑ ﯽﻫﺎﮔ
ﯽـﺒﻠﻗ يﺎـﻫ يرﺎـﻤﯿﺑ ﻪﻌـﺳﻮﺗ ﺮـﻄﺧ شزرو .ﺖﺳا ﯽﺒﻠﻗ -
و ﯽﻗوﺮﻋ ﯽـﻣ ﺶﻫﺎﮐ ﻪﺴﺋﺎﯾ نﺎﻧز رد ار يﺮﻧوﺮﮐ گﺮﺧﺮﺳ
ﺪﻫد ) 10 .(
رﺎﺸﻓ ﻢﮐ تﺎﻨﯾﺮﻤﺗ نﺎـﻧز رد يور هدﺎﯿﭘ ﺪﻨﻧﺎﻣ
ﺶﻫﺎﮐ ﯽـﺒﻠﻗ يﺎـﻬﯾ رﺎـﻤﯿﺑ ﺮـﻄﺧ ﻞﻣاﻮﻋ رد يراد ﯽﻨﻌﻣ
ﺖﺳا هداد نﺎﺸﻧ رﺎﺸﻓ ﻢﮐ تﺎﻨﯾﺮﻤﺗ ﻦﯾا يﺮﯿﮔرﺎﮐ ﻪﺑ اﺬﻟ .
ناﻮﻨﻋ ﻪﺑ يزاﻮﻫ و لﺎﺴﻧﺎﯿﻣ داﺮﻓا رد مواﺪﻣ ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ
تاﺮﯿﺛﺎﺗ ﺪﻧاﻮﺗ ﯽﻣ ﺪﻨﻤﻟﺎﺳ و هوﺮـﮔ ﻦـﯾا ياﺮـﺑ ار ﯽـﺘﺒﺜﻣ
ﺪﺷﺎﺑ ﻪﺘﺷاد هاﺮﻤﻫ ﻪﺑ ﯽﻨﺳ )
11 .(
ﯾﺮﺒﯿﻓ ﺘـﺳا ﺎـﺑ ﯽﻤﯿﻘﺘـﺴﻣ طﺎـﺒﺗرا نژﻮﻨ ﯽﻗﺎـﭼ ،سﺮ
،
ﺎــﺑ ﯽــﺳﻮﮑﻌﻣ طﺎــﺒﺗرا وLDL ﻦﯾاﺮﺑﺎــﻨﺑ .درادHDL
ﺶﯾاﺰﻓا ﺶﻫﺎﮐ وHDL
رد ﻪـﮐ ﯽـﺑﺮﭼ ﺪـﺻرد وLDL
ﻪﺠﯿﺘﻧ ﺪـﻧاﻮﺗ ﯽـﻣ ،دﻮـﺷ ﯽـﻣ ﻞﺻﺎﺣ يزاﻮﻫ تﺎﻨﯾﺮﻤﺗ ي
ﺶﻫﺎﮐ ﺐﺟﻮﻣ دﻮـﺷ نژﻮـﻨﯾﺮﺒﯿﻓ
) 12 .(
،ﺮـﮕﯾد فﺮـﻃ زا
لﺎﺳ ﻪﮐ ﯽﻧﺎﻣرد يﺎﻫ شور زا ﯽﮑﯾ يرﺎﯿﺴﺑ نﺎﻣرد رد ﺎﻫ
زا ﺐﻃ ،ﺖﺳا ﻪﺘﺷاد دﺮﺑرﺎﮐ ﺎﻫ يرﺎﻤﯿﺑ ﯽـﻧاﺮﯾا
- ﯽﻣﻼـﺳا
ﺪــﺷﺎﺑ ﯽــﻣ .
ﯽﻧﺎــﻣرد شور و مﻮــﻠﻋ زا ﯽــﮑﯾ
،ﺐــﻃ ﻦــﯾا
نﻮﺧ ﻪﯿﺒﺷ ﻪﮐ ﺖﺳا ﺖﻣﺎﺠﺣ ﻦـﯾا ﺎﺑ ،ﺖﺳا يﺪﯾرو يﺮﯿﮔ
ﺖﺳا ﯽﮔﺮﯾﻮﻣ نﻮﺧ ،ﺖﻣﺎﺠﺣ نﻮﺧ ﻪﮐ توﺎﻔﺗ )
13 ( ﻪﺑ و
دﻮـﺷ ﯽﻣ جرﺎﺧ ﺰﯿﻧ ﻒﻨﻟ ﻊﯾﺎﻣ نآ هاﺮﻤﻫ نﻮـﺧ ﻪـﺴﯾﺎﻘﻣ .
ﺮــﻈﻧ زا ﺖــﻣﺎﺠﺣ زا ﻞــﺻﺎﺣ نﻮــﺧ و ﺪــﯾرو يﺎــﻫرﻮﺘﮐﺎﻓ
داد نﺎــﺸﻧ ﯽﯾﺎﯿﻤﯿــﺷﻮﯿﺑ ﺰﯿﻣ ﻪﮐ
ا نا ﺪﯿﺳ و ﮏــﯾروا TG
يﺮﺗ) (ﺪﯾﺮﯿــﺴﯿﻠﮔ LDL, HDL
رد ﻮﺧ ن ﺖﻣﺎﺠﺣ ﻪــﺑ
يراد ﯽـــﻨﻌﻣ رﻮـــﻃ ﺮﺘﺸﯿﺑ
زا ﻮﺧ رو ن ﺪﯾ ﺖـــﺳا ) 14 .(
ﺖﻣﺎﺠﺣ ﺪـﻧاﻮﺘﯿﻣ ﻢﺘـﺴﯿﺳ
ﺎﻫ ي رد ار نﻮـﺧ زﺎﺘـﺳﻮﺌﻣﻮﻫ
اﺮﺑ ﯽﺘﺒﺜﻣ لدﺎﻌﺗ ي
ﺮﺗﺮﺑ ي دﺎـﻘﻌﻧا ﺪـﺿ داﻮﻣ ي
دراﺪـﻬﮕﻧ
،
ﻦﯿﻨﭽﻤﻫ ﯿﺗوﺮﻠﮑـﺳاوﺮﺗآ زوﺮـﺑ زا
و زﻮـﺒﻣوﺮﺗ ،ﯽﻟﻮـﺒﻣآ ﮏ
ﺎﺳ ﯾﺮ رﺎﻤﯿﺑ ﯾ ﺎـﻬ ﯾ ﯽ ﺖـﺳا قوﺮـﻋ داﺪـﺴﻧا ﺎـﻬﻧآ ﻞـﻣﺎﻋ ﻪـﮐ
ﺮﯿﮕﺸﯿﭘ ي ﻨﮐ ﺪ ) 13 .(
ﻪـﺟﻮﺗ ﻞـﺑﺎﻗ ﯽـﻧاواﺮﻓ ﻪـﺑ ﻪـﺟﻮﺗ ﺎﺑ
ﯽﻧﺎﻣرد شور ﻦﯾا ﺰﯾﻮﺠﺗ و هدﺎﻔﺘﺳا تاﺮﻈﻧ ﻪﻄﻘﻧ دﻮﺟو و
ﺖـﻣﺎﺠﺣ ﯽﺸﺨﺑﺮﺛا درﻮﻣ رد هﺪﻨﮐاﺮﭘ ﺎـﺑ و ،
دﻮـﺟو ﺮـﻄﺧ
يﻻﺎﺑ ﻼﺘﺑا ﺐﯿﺳآ ﻪﺑ يﺎﻫ
ﯽﺒﻠﻗ و ﺖﯿﻟﺎﻌﻓ يﺎـﻫ يدﺎـﻘﻌﻧا
رد نﺎﻧز
،ﻪﺴﺋﺎﯾ كﺮﺤﺗ ﻦﯾا هوﺮـﮔ ﯽﻨـﺳ ﻪـﮐ ﻻﻮـﻤﻌﻣ ﺎـﺑ
ﯽﮕﺘﺴﺸﻧزﺎﺑ نﺎﻧز
هاﺮﻤﻫ ﻞﻏﺎﺷ .ﺖـﺳا ﻦﯿﯾﺎﭘ رﺎﯿﺴﺑ ،ﺖﺳا
ﻪـﮐ ﺖﻓﺮﮔ راﺮﻗ ﯽﺳرﺮﺑ درﻮﻣ ﺖﻬﺟ ﻦﯾا زا ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ تﺎﯾاور و ﯽﻣﻼﺳا ﯽﻧاﺮﯾا ﺐﻃ ﺪﮐﻮﻣ يﺎﻫ ﻪﯿﺻﻮﺗ ﻢﻏر ﯽﻠﻋ نﺎـﻣرد رد ﺎـﻫ نآ دﺮﺑرﺎـﮐ و شزرو و ﺖـﻣﺎﺠﺣ مﺎﺠﻧا ﺮﺑ ﺎــﻤﯿﺑ زا يرﺎﯿــﺴﺑ ﺎــﻫ ير
، ﻪــﻨﯿﻣز رد ﯽﮐﺪــﻧا تﺎــﻘﯿﻘﺤﺗ
ﺖﺳا هﺪﺷ مﺎﺠﻧا ﺖﻣﺎﺠﺣ ﺮـﺛا ﻪـﻌﻟﺎﻄﻣ ﻦـﯾا رد ﻦﯾاﺮﺑﺎـﻨﺑ
ناﺰـﯿﻣ ﺮﺑ يزاﻮﻫ تﺎﻨﯾﺮﻤﺗ و ﺖﻣﺎﺠﺣ LDL , HDL
و
.ﺪﺷ ﯽﺳرﺮﺑ نژﻮﻨﯾﺮﺒﯿﻓ
ﺎﻫ شور و داﻮﻣ
اـﯾ ﻦ ﺶﻫوﮋـﭘ و هدﻮـﺑ ﯽـﺑﺮﺠﺗ ﻪـﻤﯿﻧ زا
هوﺮـﮔ ود ﺎـﺑ
ﺶﯾﺎﻣزآ و ﮏـﯾ هوﺮـﮔ لﺮـﺘﻨﮐ ﻪـﺑ ﻞﮑـﺷ ﺶﯿﭘ نﻮـﻣزآ و
ﺲﭘ نﻮﻣزآ رد ﺮﻈﻧ ﻪﺘﻓﺮﮔ ﻪﻧﻮﻤﻧ .ﺪﺷ نﺎﻧز ار ﺶﻫوﮋﭘ يﺎﻫ
ﯽﻨﺳ هدوﺪﺤﻣ رد ﻪﺴﺋﺎﯾ 55
ﺎﺗ 65 ترﻮـﺻ ﻪـﺑ ﻪـﮐ لﺎﺳ
كرﺎﭘ رد ﺮﻤﺘﺴﻣ ﺮﯿﻏ و ﯽﺤﯾﺮﻔﺗ ﻦﻟﺎـﺳ و ﺎﻫ
ﯽـﺷزرو يﺎﻫ
ﻪﻘﻄﻨﻣ دوﺪﺤﻣ 7
لﺎﺳ رد ناﺮﻬﺗ يراﺮﻬﺷ 1399
رﻮـﻀﺣ
ﺐـﻠﻃواد نﺎﮔﺪـﻨﻨﮐ ﺖﮐﺮﺷ زا ﻪﮐ ﺪﻧداد ﻞﯿﮑﺸﺗ ،ﺪﻨﺘﺷاد ﻣﺎﺷ ﻪﻌﻟﺎﻄﻣ ﻪﺑ دورو رﺎﯿﻌﻣ سﺎﺳا ﺮﺑ ﺪﻨﻤﻓﺪﻫ ترﻮﺻ ﻪﺑ
ﻞ
مﺪــﻋ ،ﻪــﺴﺋﺎﯾ نﺎــﻧز لﺎﻤﻌﺘــﺳا
ــﯿﻧﺎﺧد
،تﺎ يرﺎــﻤﯿﺑ مﺪــﻋ
مﺪــﻋ و (... و ﻻﺎــﺑ نﻮﺧرﺎــﺸﻓ و ﺖــﺑﺎﯾد ﻪــﺑ ﻼﺘﺑا)ﯽــﺻﺎﺧ ،ﺪــﯿﭙﯿﻟ هﺪــﻨﻫﺎﮐ و صﺎــﺧ يﺎــﻫوراد فﺮــﺼﻣ ﻦﺘــﺷاد
ﯿﺷﻮﻫ رﺎ ي ﯽﯾﺎﻧاﻮﺗ و مﺎﺠﻧا
ﯿﻟﺎﻌﻓ ﺖ رو ﺷز ﯽ نوﺪﺑ ﯽﮕﺘﺴﺑاو
ﯾد ﻪﺑ ناﺮﮕ 40 ترﻮـﺻ ﻪـﺑ ﺲﭙـﺳ و ﺪﻧﺪـﺷ ﻪﺘﻓﺮﯾﺬﭘ ﺮﻔﻧ
ﯽﻓدﺎﺼﺗ 30 ﻣ لوﺪﺟ سﺎﺳا ﺮﺑ) ﺮﻔﻧ نﺪﺷ بﺎﺨﺘﻧا (نﺎﮔرﻮ
ﻪﮐ ﺮﺑ سﺎﺳا وBMI VO2max ﻪﺳ رد
هوﺮﮔ ﺖـﻣﺎﺠﺣ
) 10 (ﺮﻔﻧ
، ) يزاﻮﻫ ﻦﯾﺮﻤﺗ هوﺮﮔ 10
(ﺮﻔﻧ و لﺮـﺘﻨﮐ هوﺮـﮔ
) 10 (ﺮﻔﻧ زا ﯽﻫﺎـﮔآ زا ﺲﭘ نﺎﺒﻠﻃواد .ﺪﻨﺘﻓﺮﮔ راﺮﻗ هﻮـﺤﻧ
اﺮﺟا ي ﺮﻤﺗ تﺎﻨﯾ و اﺮﺟا نﺎﻣز تﺪﻣ ي
ﻘﺤﺗ ﻖﯿ ﻤﮑﺗ ﺎﺑ ، ﻞﯿ و
ﺎــﻀﻣا ي مﺮﻓ ﺎــﻫ ي ﺎــﺿر ﺖﯾ ﺘــﺳرﺪﻨﺗ ﻪﻣﺎﻨــﺸﺳﺮﭘ ،ﻪﻣﺎﻧ ﯽ
و
ﻪﻘﺑﺎﺳ ﮑﺷﺰﭘ ﯽ ﺎﻣآ ﯽﮔد ﻘﺤﺗ رد ﺖﮐﺮﺷ ﺖﻬﺟ ار دﻮﺧ ﻖـﯿ
زا هدﺎﻔﺘـﺳا ﺎـﺑ ﺐـﻠﻗ نﺎﺑﺮﺿ ﺮﺜﮐاﺪﺣ ﺲﭙﺳ .ﺪﻧدﺮﮐ مﻼﻋا لﻮــﻣﺮﻓ ﻦــﺳ) × 7/
0 208– ) ( 15 ( و ﺪــﻣآ ﺖــﺳد ﻪــﺑ
ﺮﺜﮐاﺪﺣ ﺴﮐا نﮋﯿ ﻓﺮﺼﻣ ﯽ VO2max) (
نﻮـﻣزآ مﺎﺠﻧا ﺎﺑ
نار ﻞﺗﺎﺷ ﺪﻣآ ﺖﺳد ﻪﺑ ﺮﯾز لﻮﻣﺮﻓ زا هدﺎﻔﺘﺳا ﺎﺑ
) 16 (.
182 /0 + 95 /0
× )8 / 35 - 65 /6 × ﺮﺜﮐاﺪﺣ ﺮﺳ ﻋ (ﺖ VO2max =
نزو لﻮـﻣﺮﻓ زا هدﺎﻔﺘﺳا ﺎﺑ دﺮﻓ ﺮﻫBMI (مﺮﮔﻮـﻠﯿﮐ)
ﺴﻘﺗ ﻢﯿ ﺪﻗ روﺬﺠﻣ ﺮﺑ (ﺮﺘﻣ)
هزاﺪﻧا ﺮﯿﮔ ي ﺪـﺷ . ﻪـﻧﻮﻤﻧ ﺎﻫ ي
نﻮﺧ ﻪﺑ ﻣ ناﺰﯿ 8 ﻣ ﯽﻠﯿ ﻟ زا ﺪﻌﺑ ﺮﺘﯿ 12
ﺎﺘـﺷﺎﻧ ﺖﻋﺎـﺳ ﯽﯾ
و
رد 2 ﺖﺑﻮﻧ ، 24 ﭘ ﺖﻋﺎﺳ ﺶﯿ ﻟوا زا ﻦﯿ ﺮـﻤﺗ ﻪـﺴﻠﺟ ﻦﯾ
48
ﺮـﺧآ زا ﺲـﭘ ﺖﻋﺎﺳ ﻦﯾ
ﺮﻤﺗ ﻪـﺴﻠﺟ ﯽـﻨﯾ
ﯽـﺳرﺮﺑ ﺖـﻬﺟ
يﺎﻫرﻮﺘﮐﺎﻓ LDL, HDL
و نژﻮﻨﯾﺮﺒﯿﻓ ﻪﺑ و يروآ ﻊﻤﺟ
ﻪـﻧﻮﻤﻧ ﺲﭙﺳ .ﺪﻧﺪﺷ هداد لﺎﻘﺘﻧا هﺎﮕﺸﯾﺎﻣزآ ﺎـﺑ ﯽﻧﻮـﺧ ﺎﻫ
3000 تﺪــﻣ ﻪــﺑ ﻪـﻘﯿﻗد رد رود 15
هﺎﮕﺘــﺳد ﺎــﺑ ﻪـﻘﯿﻗد
Universal 320R نآ مﺮــﺳ و هﺪــﺷ ژﻮﯿﻔﯾﺮﺘﻧﺎــﺳ
يﺎﻣد ﺎﺑ لﺎﭽﺨﯾ رد و يزﺎﺳاﺪﺟ 70
- ﯽﺘﻧﺎﺳ ﻪﺟرد ـﮔ
داﺮ
ﻮـﻨﯾﺮﺒﯿﻓ ﺶﺠﻨﺳ يﺮﯿﮔ هزاﺪﻧا ياﺮﺑ .ﺪﻧﺪﺷ يراد ﻪﮕﻧ نژ
شور زا سوﻼﮐ هﺎﮕﺘﺳد و ﺮﺘﻣﻮﻟﻮﮔاﻮﮐ
مﺎـﻤﺗ ﮏـﯿﺗﺎﻣﻮﺗا
) Sinnowa رﻮﺸﮐ (
ﻦﯿﭼ و ﺖﯿﮐ يﺎـﻫ ﯽـﺼﺼﺨﺗ ياﺮـﺑ
هزاﺪﻧا يﺮﯿﮔ LDL, HDL هدﺎﻔﺘﺳا
ﺪﺷ .
ﻦﯾﺮﻤﺗ ﺎﺑ يزاﻮﻫ 50-75
ﺪﺻرد نﺎﺑﺮﺿ ﺧذ ﺐﻠﻗ هﺮﯿ
(ﺪﻨﻤـﺷﻮﻫ يﺎﻫ ﺖﻋﺎﺳ و رﻼﭘ ﺞﻨﺳ نﺎﺑﺮﺿ زا هدﺎﻔﺘﺳا ﺎﺑ) ﺮـﮔ ﻞﻣﺎـﺷ ﻦﯾﺮـﻤﺗ ﻞﮑﺗوﺮﭘ .ﺪﺷ اﺮﺟا ﻪﺘﻔﻫ ﺶﺷ ﯽﻃ م
ندﺮﮐ ﻪﺑ تﺪﻣ 10 ﻪﻘﯿﻗد ﺎﺑ مﺎﮔ نﺎﺳآ و تﺎﮐﺮﺣ ﯽﺸﺸﮐ
دﻮﺑ ) تﺪﻣ ﻪﺑ ﺲﭙﺳ و 6
- 16 ﻗد ( ﯿ ﻪﻘ ﺮﻤﺗ ﯾ ﻦ زاﻮﻫ ي ود) ي
ﺑوﺎﻨﺗ مﺮﻧ ﯽ ( و ﺲﭙﺳ ﻪﺑ ) تﺪﻣ 20 - 30 ﻪﻘﯿﻗد ( زا تﺎﮐﺮﺣ
ةدﺎﺳ ﮏﯿﺑوﺮﯾا ﮓﻨﻫﺎﻤﻫ ﺎﺑ
ﯽﻘﯿﺳﻮﻣ )
ﺖﮑﭙﻤﯾاﻮﻟ (
هدﺎﻔﺘﺳا
ﺪﺷ تﺎﮐﺮﺣ . ﺖﮑﭙﻤﯾاﻮﻟ ترﺎﺒﻋ
ﺪﻧا زا : مﺎـﮔ
،ﺎـﺟرد مﺎـﮔ
مﺎﮔ،نﺎﺳآ ﺸﻫ و ﺖﻔﻫ
،ﺖ مﺎﮔ ﻪـﺑ
،ﻮـﻠﺟ مﺎـﮔ ﻪـﺑ
،ﺐـﻘﻋ
،ﻮﺒﻣﺎﻣ مﺎﮔ
،ﯽﻧﺪﻧار مﺎﮔ و ﻮﻧاز ) ﻪﮐ رد ﺮﻫ ﻪﺴﻠﺟ ﺜﮐاﺪﺣ ﺮ
زا ﺐﯿﮐﺮﺗ رﺎﻬﭼ ﺖﮐﺮﺣ هدﺎﻔﺘﺳا ﺪﺷ .(
رد نﺎﯾﺎﭘ ﺮﻫ ﻪﺴﻠﺟ
5 ﻪﻘﯿﻗد ﺖﺸﮔﺮﺑ ﻪﺑ ﺖﻟﺎﺣ ﻪـﯿﻟوا ﺎـﺑ تﺎـﮐﺮﺣ ﯽـﺸﺸﮐ
و
مارآ مﺎﺠﻧا ﺪﺷ .
ﺐـﻠﻃواد داﺮﻓا ﻪﮐ دﻮﺑ ترﻮﺻ ﻦﯾا ﻪﺑ ﺖﻣﺎﺠﺣ شور ﻪﻤﯿﻧ زا ﺮﻤﮐ ﻪﻨﻫﺮﺑ ﯽﻣ ﺪﻧﻮﺷ و ﺖﯿﻌﺿو رد ﻪﺘﺴﺸﻧ
يور
ﺖﺨﺗ صﻮﺼﺨﻣ راﺮﻗ
ﯽﻧﻮﻔﻋ ﺪﺿ زا ﺪﻌﺑ ﺲﭙﺳ ﺪﻧﺮﯿﮔ ﯽﻣ
ﺶﮐدﺎﺑ صﻮﺼﺨﻣ ناﻮﯿﻟ ﻖﯾﺮﻃ زا ﺖﻣﺎﺠﺣ ﻊﺿﻮﻣ ندﺮﮐ ﯽﺘﺸﭘ يﺎﻫ هﺮﻬﻣ يور ﺮﺑ وT3
ناﺰـﯿﻣ .ﺪﺷ مﺎﺠﻧا T4
و هﺪﺷ مﺎﺠﻧا يو ﺖﺳﻮﭘ ماﻮﻗ و دﺮﻓ ﺎﺑ ﺐﺳﺎﻨﺘﻣ ﺶﮐدﺎﺑ ﺖﺳﻮﭘ نﺪﯿﺸﮐ ياﺮﺑ ﺐﺳﺎﻨﻣ ﺪﺣ )
cupping (
نورد ﻪﺑ
دوﺪﺣ ﺶﮑﻣ فﺮﻇ 1
ﺎﺗ 5/
1 ﺪـﺣ ﻦﯾﺮﺗﻻﺎﺑ زا ﺮﺘﻣ ﯽﺘﻧﺎﺳ
و دﻮـﺷ ﯽـﻣ هﺪـﯿﮑﻣ ﺶـﮑﻣ فﺮـﻇ ﻪـﺒﻟ ﺎﺗ ﺖﺳﻮﭘ ﺪﺒﻨﮔ هﺎﮕﻧآ و ﻪﺘﺷادﺮﺑ ار ﺶﮐ دﺎﺑ ﺲﭙﺳ ﺎـﺑ
ﻎـﯿﺗ هرﺎﻤـﺷ 11 شاﺮﺧ
يﺎﻫ ﯽﺤﻄﺳ نﺪﺑ ﯽﻟﻮﻃ رﻮﺤﻣ ﺎﺑ يزاﻮﻣ يدﻮﻤﻋ
ﻪﻠﺻﺎﻓ ﺎﺑ و 5
- 3 دورو ﻞـﺤﻣ ﻢﯿـﻨﮐ ﯽﻣ دراو ﺮﺘﻣ ﯽﻠﯿﻣ
زا ﺎﻫ شاﺮﺧ ﺪﺣ و هﺪﺷ هﺪﯿﮑﻣ ﺖﺳﻮﭘ ﻪﻠﻗ ﺮﺑ ﻎﯿﺗ نﺪﻣآ ﻧ ﯽﻟﻮﻃ ﺮﻈ 25
- 20 داﺪـﻌﺗ ﺖﻬﺟ زا و ﺮﺘﻣ ﯽﻠﯿﻣ 10
ﺎـﺗ
30 ﻪـﮐ ﺖـﺳا ﻪـﻧﻮﮔ ﻪـﺑ شاﺮـﺧ ﻖﻤﻋ و ﺪﺷﺎﺑ ﯽﻣ دﺪﻋ ﻪـﻠﺣﺮﻣ ﻦـﯾا زا ﺪﻌﺑ .ﺪﻫد شﺮﺑ ار ﺖﺳﻮﭘ مرد و مرﺪﯿﭘا مﺎـﺠﻧا ﺎـﺑ رﺎـﺒﻨﯾا و ﻪﺘـﺷاﺬﮔ ﯽﻠﺒﻗ ﻊﺿﻮﻣ رد ار ﺶﮐدﺎﺑ ﯽـﻣ جرﺎﺧ هﺪﺷ دﺎﺠﯾا يﺎﻬﺷاﺮﺧ زا نﻮﺧ ،دﺪﺠﻣ ﺶﮑﻣ زا ﺲـﭘ ﺶـﮐ دﺎـﺑ مﺎـﺠﻧا تﺎﻌﻓد داﺪﻌﺗ دﻮﺷ ندز ﻎـﯿﺗ
ﺮﺜﮐاﺪﺣ 3 ﻦﯾا ﯽﻃ هﺪﺷ جرﺎﺧ نﻮﺧ ناﺰﯿﻣ و دﻮﺑ ﻪﺒﺗﺮﻣ
زا ﺲﭘ ﻪﺒﺗﺮﻣ ﻪﺳ 4
ناﺰـﯿﻣ ﻪـﺑ ﻪﻘﯿﻗد 70
ﺮـﺘﯿﻟ ﯽـﻠﯿﻣ
ﯽﻣ ﺪﺷﺎﺑ ) 17 ( و رﺎﺑود ﺖﻣﺎﺠﺣ داﺪﻌﺗ ﺶﻫوﮋﭘ ﻦﯾا رد .
) ﺖﻓﺮﮔ مﺎﺠﻧا ﻢﺠﻨﭘ و مود ﻪﺘﻔﻫ رد 18
.(
ﺲــﭘ زا ﻊــﻤﺟ روآ ي
،تﺎــﻋﻼﻃا رﻮــﻈﻨﻣ ﻪــﺑ
ﺰﺠﺗ ﻪــﯾ و
ﻠﺤﺗ ﻞﯿ رﺎﻣآ ي رد اﺪﺘﺑا زا نﻮﻣزآ فﻮﻧﺮﯿﻤـﺳا فاﺮﮔﻮﻣﻮﻠﮐ
اﺮﺑ ي ﻤﻃا نﺎﻨﯿ زا زﻮﺗ ﻊﯾ ﺒﻃ ﯽﻌﯿ ﻊﻤﺟ تﺎﻋﻼﻃا روآ
ي هﺪﺷ
اﺮﺑ و ي ﻨﮕﻤﻫ ﯽ راو ﺲﻧﺎﯾ ﺎﻫ ﻮﻟ نﻮﻣزآزا ن
ﻪـﺑ .ﺪﺷ هدﺎﻔﺘﺳا
ﻟد ﻞﯿ ﺒﻃ ﯽﻌﯿ زﻮﺗ ندﻮﺑ ﻊﯾ
هداد نﻮﻣزآ زا ،ﺎﻫ يﺎﻫ
ﺲﻧﺎﯾراو
) اﻮﮑﻧآ ANCOVA (
اﺮﺑ ي ﺎﻘﻣ ﻪـﺴﯾ ـﺑ ﻦﯿ هوﺮﮔ ﺎـﻫ ﺎـﺑ و
نﻮﻣزآ اﺮﺑ ﻪﺘﺴﺑاو t ي
ﺎﻘﻣ ﻪﺴﯾ ﭘ ﺶﯿ ﺲﭘو نﻮﻣزآ و نﻮﻣزآ
ﺎـﺑ version19 SPSS رادﺎـﻨﻌﻣ ﺢﻄـﺳرد
ي P<0.05
ﻠﺤﺗ ﻞﯿ ﺎﺘﻧ .ﺖﻓﺮﮔ ترﻮﺻ ﺞﯾ
ﻣ ترﻮﺻ ﻪﺑ ﻦﯿﮕﻧﺎﯿ
فاﺮـﺤﻧاو
ﻌﻣ ﻪﺋارارﺎﯿ ﺖﺳا هﺪﺷ .
لوﺪﺟ 1 يزاﻮﻫ ﻦﯾﺮﻤﺗ ﻞﮑﺗوﺮﭘ : دﺮﺳ نﺎﻣز تﺪﻣ
(ﻪﻘﯿﻗد)ندﺮﮐ
ﻦﯾﺮﻤﺗ تﺪﻣ ﮏﯿﺑوﺮﯾا
ﻦﯿﺑ ﺖﺣاﺮﺘﺳا (ﻪﻘﯿﻗد) ﻪﻠﻫو ﺮﻫ
تﺪﻣ نﺎﻣز ﻦﯾﺮﻤﺗ
(ﻪﻘﯿﻗد) ﯽﻣواﺪﺗ نﺪﯾود
تﺪﺷ ﻦﯾﺮﻤﺗ ﻪﻨﺸﯿﺑ ﺐﻠﻗ نﺎﺑﺮﺿ
تﺪﻣ نﺎﻣز مﺮﮔ
(ﻪﻘﯿﻗد) ندﺮﮐ
ﻪﺘﻔﻫ
5 20 1 (63*2) % 50 10 1
5 20 1 8 (4*2) % 55 10 2
5 25 1 10(5*2) % 60 10 3
5 25 1 126(*2) % 65 10 4
5 30 1 14(7*2) % 70 10 5
5 30 1 16(8*2) % 75 10 6
لوﺪﺟ 2 دراﺪﻧﺎﺘﺳا فاﺮﺤﻧا و ﻦﯿﮕﻧﺎﯿﻣ : HDL, LDL
و ﯾﺮﺒﯿﻓ ﯽﺸﻫوﮋﭘ هوﺮﮔ ﻪﺳ رد نژﻮﻨ
هوﺮﮔ نﻮﻣزآ ﺶﯿﭘ
(mg/dl) نﻮﻣزآ ﺲﭘ
) mg/dl ﺮﯾدﺎﻘﻣ (
t ﺮﯾدﺎﻘﻣ p
نورد) (ﯽﻫوﺮﮔ ﺪﺻرد
تاﺮﯿﯿﻐﺗ ﺮﯾدﺎﻘﻣ
F ﺮﯾدﺎﻘﻣ p
ﻦﯿﺑ) (ﯽﻫوﺮﮔ وﺮﯿﭘﺎﺷ
- ﮏﻠﯾو ﺲﭘ) (نﻮﻣزآ ﻦﯾﻮﻟ
ﺲﭘ) (نﻮﻣزآ
نژﻮﻨﯾﺮﺒﯿﻓ ﺖﻣﺎﺠﺣ
49 / 39 6/± 260 44 / 19 85± / 245 85 /2 029 /0
% 6 - 4/
39 04 /0 82 /0 27
/0 - 13% /0015 - /429 234/29±19/ 66 267/13±13/ 66 يزاﻮﻫ
لﺮﺘﻨﮐ 7/
33 93± / 259 06 / 36 85± / 263 09 /1 31 /0
% 1
LDL ﺖﻣﺎﺠﺣ
2/
20 8/± 124 11 / 29 9/± 102 12 /7 04 /0
% 18 - 61 /6 001 /0 57 /0 37
/0 - 26% /0005 - /651 889/±154/ 1196/±15/ 45 يزاﻮﻫ
لﺮﺘﻨﮐ 5/
11 16± / 123 82 / 11 6/± 121 87
/0 12 /0
% 1
HDL ﺖﻣﺎﺠﺣ
37 /7 1/± 44 45
/ 9 60± / 49 12 /7 04 /0
% 12 19 /5 003 /0 58 /0 41
/0 26% /0001 - /651 54/80± /632 434/± 56/ يزاﻮﻫ
لﺮﺘﻨﮐ 49
/ 6 20± / 42 82 / 11 6/± 41 87 /0 12 /0
% 2 -
ﻪﺘﻓﺎﯾ ﺎﻫ
لوﺪﺟ ﺞﯾﺎﺘﻧ 2
داد ﺪﻫﺪﯿﻣ نﺎﺸﻧ ه
ﻫرﻮﺘﮐﺎﻓ ﯽﻣﺎﻤﺗ رد ﺎﻫ ﺎ
هداد ﺲﻧﺎﯾراو و لﺎﻣﺮﻧ ـﺳ ﻦﯿـﺑ ﻦﯿﻨﭽﻤﻫ .ﺪﺷﺎﺑ ﯽﻣ ﺮﺑاﺮﺑ ﺎﻫ
ﻪ
ﯽﻣﺮـﺳ ﺖﻈﻠﻏ رد رد لﺮﺘﻨﮐ و يزاﻮﻫ ،ﺖﻣﺎﺠﺣ نژﻮـﻧوﺮﺒﯿﻓ
ﯽـــﻨﻌﻣ توﺎـــﻔﺗ ) دراد دﻮـــﺟو يراد
04 /0 نﻮـــﻣزآ .(P=
ﯽﺒﯿﻘﻌﺗ ) ﺖـﻣﺎﺠﺣ هوﺮﮔ ﻪﮐ داد نﺎﺸﻧ LSD
021 /0 (P =
) يزاﻮـﻫ هوﺮـﮔو 01
/0 ﯽـﻨﻌﻣ ﺶﻫﺎـﮐ نژﻮـﻧوﺮﺒﯿﻓ رد (P
هوﺮـﮔ ﻦﯿـﺑ ﻦﯿﻨﭽﻤﻫ . ﺪﻨﺘﺷاد لﺮﺘﻨﮐ هوﺮﮔ ﻪﺑ ﺖﺒﺴﻧ يراد ) ﺖــﻣﺎﺠﺣ 031
/0 ﺺﺧﺎــﺷ ﻦــﯾا رد يزاﻮــﻫ هوﺮــﮔ ﺎــﺑ (P=
ﯽﻨﻌﻣ توﺎﻔﺗ نﻮـﻣزآ ﺞﯾﺎـﺘﻧ .ﺪـﺷ هﺪﯾد يراد
ﺰـﯿﻧ ﯽـﺟوزt
ﯽﻨﻌﻣ ﺶﻫﺎﮐ رد نﻮـﻣزآ ﺲـﭘ ﻪـﺑ ﺖﺒﺴﻧ نﻮﻣزآ ﺶﯿﭘ يراد
ﯽﻣﺮﺳ ﺖﻈﻠﻏ ) ﺖـﻣﺎﺠﺣ هوﺮﮔ رد نژﻮﻧوﺮﺒﯿﻓ
029 /0
= و (P
يزاﻮﻫ ) 015 /0 ﺲﭘ ار (P = ﯽﻣ نﺎﺸﻧ ﻪﻠﺧاﺪﻣ زا .ﺪﻫد
ﺎﺘﻧ ﻦﯿﻨﭽﻤﻫ ﺖـﻣﺎﺠﺣ هوﺮـﮔ ﻪـﺳ ﻦﯿﺑ ﺪﻫﺪﯿﻣ نﺎﺸﻧ ﺞﯾ
،
ﯽﻣﺮﺳ ﺖﻈﻠﻏ رد رد لﺮﺘﻨﮐ و يزاﻮﻫ LDL
ﯽـﻨﻌﻣ توﺎﻔﺗ -
) دراد دﻮـــﺟو يراد 001
/0 ﯽـــﺒﯿﻘﻌﺗ نﻮـــﻣزآ .(P=
LSD
) ﺖـﻣﺎﺠﺣ هوﺮﮔ ﻪﮐ داد نﺎﺸﻧ 031
/0 يزاﻮـﻫ هوﺮـﮔو (P =
) 001 /0 رد (P هوﺮـﮔ ﻪﺑ ﺖﺒﺴﻧ يراد ﯽﻨﻌﻣ ﺶﻫﺎﮐLDL
ﺷاد لﺮﺘﻨﮐ ﺖـﻣﺎﺠﺣ ﻦﯿـﺑ ﻦﯿﻨﭽﻤﻫ .ﺪﻨﺘ
) 005 /0 ﺎـﺑ ( P =
ﯽﻨﻌﻣ توﺎﻔﺗ ﺺﺧﺎﺷ ﻦﯾا رد يزاﻮﻫ هوﺮﮔ .ﺪـﺷ هﺪـﯾد يراد
نﻮﻣزآ ﺞﯾﺎﺘﻧ ﯽـﻨﻌﻣ ﺶﻫﺎـﮐ ﺰـﯿﻧ ﯽـﺟوزt
نﻮـﻣزآ ﺲـﭘ راد
ﯽﻣﺮـﺳ ﺖـﻈﻠﻏ رد نﻮـﻣزآ ﺶﯿﭘ ﻪﺑ ﺖﺒﺴﻧ هوﺮـﮔ رد LDL
) ﺖـﻣﺎﺠﺣ 04
/0 ﮏـﯿﺑوﺮﯾا يزاﻮـﻫ و (P=
) 005 /0 ار (P =
ﺪﻫد ﯽﻣ نﺎﺸﻧ ﻪﻠﺧاﺪﻣ زا ﺲﭘ .
ﻦﯿﺑ ﻦﯿﻨﭽﻤﻫ رد لﺮـﺘﻨﮐ و يزاﻮـﻫ ، ﺖﻣﺎﺠﺣ هوﺮﮔ ﻪﺳ
ﯽﻣﺮـﺳ ﺖـﻈﻠﻏ رد HDL
ﯽـﻨﻌﻣ توﺎـﻔﺗ دراد دﻮـﺟو يراد
) 003 /0 ﯽﺒﯿﻘﻌﺗ نﻮﻣزآ .(P=
هوﺮـﮔ ﻪـﮐ داد نﺎﺸﻧ LSD
) ﺖﻣﺎﺠﺣ 021
/0
= ) يزاﻮـﻫ هوﺮﮔ و (P 01
/0
= رد (P HDL
ﺪﻨﺘــﺷاد لﺮــﺘﻨﮐ هوﺮــﮔ ﻪــﺑ ﺖﺒــﺴﻧ يراد ﯽــﻨﻌﻣ ﺶﯾاﺰــﻓا هوﺮﮔ ﻦﯿﺑ ﻦﯿﻨﭽﻤﻫ ) ﺖـﻣﺎﺠﺣ يﺎـﻫ
031 /0 هوﺮـﮔ ﺎـﺑ (P =
ﯽﻨﻌﻣ توﺎﻔﺗ ﺺﺧﺎﺷ ﻦﯾا رد يزاﻮﻫ ﺞﯾﺎـﺘﻧ .ﺪﺷ هﺪﯾد يراد
نﻮﻣزآ ﯽﻨﻌﻣ ﺶﯾاﺰﻓا ﺰﯿﻧ ﯽﺟوزt ﻪـﺑ ﺖﺒـﺴﻧ نﻮﻣزآ ﺲﭘ راد
ﯽﻣﺮـﺳ ﺖـﻈﻠﻏ رد نﻮـﻣزآ ﺶﯿﭘ ﺖـﻣﺎﺠﺣ هوﺮـﮔ رد HDL
) 04 /0 ) ﮏــﯿﺑوﺮﯾا يزاﻮــﻫ و (P=
001 /0 زا ﺲــﭘ ار (P =
لوﺪﺟ) ﺪﻫد ﯽﻣ نﺎﺸﻧ ﻪﻠﺧاﺪﻣ 2
( .
يﺮﯿﮔ ﻪﺠﯿﺘﻧ و ﺚﺤﺑ
ﺞﯾﺎﺘﻧ ﻦﯾا ﻖﯿﻘﺤﺗ رد ﻪﻄﺑار ﺎﺑ خﺮﻤﯿﻧ يﺎﻫ يﺪﯿﭙﯿﻟ نﺎﺸﻧ
،داد ﺐﻗﺎﻌﺘﻣ 6
،ﺖـﻣﺎﺠﺣ و يزاﻮـﻫ ﯽـﺷزرو ﺖـﯿﻟﺎﻌﻓ ﻪﺘﻔﻫ
ناﺰﯿﻣ ﻦﯿﺌﺗوﺮﭘﻮﭙﯿﻟ لوﺮﺘﺴﻠﮐ
ﻢـﮐ لﺎـﮕﭼ ﺶﻫﺎـﮐ و ناﺰـﯿﻣ
ﻦﯿﺌﺗوﺮﭘﻮﭙﯿﻟ لﺎﮕﭼﺮﭘ لوﺮﺘﺴﻠﮐ
ﺶﯾاﺰـﻓا ﻪـﺘﻓﺎﯾ شزرو .دﻮـﺑ
ﺶﻫﺎﮐ ﺚﻋﺎﺑ 26
يﺪﺻرد ﺶﯾاﺰـﻓا وLDL
26 يﺪـﺻرد
HDL ﺶﻫﺎﮐ ﺚﻋﺎﺑ ﺖﻣﺎﺠﺣ ﻦﯿﻨﭽﻤﻫ و ﺪﺷ 18
يﺪﺻرد
ﺶﯾاﺰـــﻓا وLDL 12
يﺪـــﺻرد زا .ﺪـــﺷHDL
ﻪـــﻠﻤﺟ
تﺎﻘﯿﻘﺤﺗ مﺎﺠﻧا
ﻪﺘﻓﺮﮔ ﯽﻣ نارﺎـﮑﻤﻫ و هداز ﯽـﺴﻤﺷ ﻪﺑ ناﻮﺗ
) 1399 )(
19 ) نارﺎﮑﻤﻫ و ماﺮﻬﺑ و ( 1397
)(
20 هرﺎﺷا ( دﻮﻤﻧ .
ﻦــﯾا ﻪــﺘﻓﺎﯾ ﺎﻫ ﻮــﺴﻤﻫ ﺎــﺑ ﻪــﺘﻓﺎﯾ يﺎﻫ ﺮــﺿﺎﺣ ﻪــﻌﻟﺎﻄﻣ ﺖــﺳا
.
ﺖﯿﻟﺎﻌﻓ يﺎﻫ
ًﻻﺎـﻤﺘﺣا يزاﻮﻫ زا
ﺪـﻨﭼ ﻖـﯾﺮﻃ ﺮـﺛا ﺖـﻈﻓﺎﺤﻣ
هﺪﻨﻨﮐ ﻞﺑﺎﻘﻣ رد رﺎﻤﯿﺑ
ي يﺎﻫ ﯽﺒﻠﻗ ﯽﻗوﺮﻋ
،ﺪﻧراد ﻪﮐ ﻞﻣﺎـﺷ
ﺶﯾاﺰﻓا ﻢﺠﺣ نﻮﺧ و
،ﺎﻤﺳﻼﭘ ﺶﻫﺎﮐ ﺖﻈﻠﻏ ﺶﯾاﺰـﻓا ،نﻮﺧ
ﻢﺠﺣ ﻪﺑﺮﺿ يا و ﺶﯾاﺰﻓا نﮋﯿـﺴﮐا ﺮﺜﮐاﺪـﺣ ﯽﻓﺮـﺼﻣ
ﺖـﺳا
) 21 ﺶﯾاﺰــﻓا ﺮــﺿﺎﺣ ﺶﻫوﮋــﭘ ﺞﯾﺎــﺘﻧ ﻦﯿــﻨﭽﻤﻫ .(
وHDL
ﺶﻫﺎــﮐ ﯽﻧﺎــﻀﻣر .داد نﺎــﺸﻧ ﺖــﻣﺎﺠﺣ زا ﺲــﭘ ارLDL
) 1391 ﻪﻌﻟﺎﻄﻣ رد ( ناﺰـﯿﻣ ﻦﯿﺑ ﻪﮐ داد نﺎﺸﻧ يا
ردHDL
دراد دﻮـﺟو يرادﺎﻨﻌﻣ فﻼﺘﺧا ﺖﻣﺎﺠﺣ زا ﺪﻌﺑ و ﻞﺒﻗ )
17 .(
) يرﺎﺳﺎﯿﻧ 2007
ﻪﻈﺣﻼﻣ ﻞﺑﺎﻗ ﺶﻫﺎﮐ ( ﺖـﻣﺎﺠﺣ زا ﺲﭘ يا
ﺖﺒﺴﻧ رد LDL/HDL
دﺮﮐ هﺪﻫﺎﺸﻣ )
22 قﻮﻓ ﺞﯾﺎﺘﻧ ﻪﮐ .(
ندﺮﮐ جرﺎﺧ ﺎﺑ ﺖﻣﺎﺠﺣ .ﺖﺳا ﺮﺿﺎﺣ ﺶﻫوﮋﭘ ﺞﯾﺎﺘﻧ ﺎﺑ ﻮﺴﻤﻫ مﺎــﺠﻧا نﻮــﺧ نﺪــﺷ ﻪﻧﮋﯿــﺴﮐا ﺪــﻨﯾاﺮﻓ رد ﻪــﮐ ﯽــﺑﺮﭼ تارذ ﯽﻣ ﻘﺘﻧا ﺚﻋﺎﺑ ،دﻮﺷ ﯽﺠﯾرﺪـﺗ لﺎ
ﺮﺗدﺎـﺸﮔ قوﺮـﻋ ﻪـﺑLDL
ﯽﻣ يﺮﯿﮔﻮــﻠﺟ قوﺮــﻋ داﺪــﺴﻧا و بﻮــﺳر زا و هﺪــﺷ .ﺪــﻨﮐ
ﻪـﻠﺗ دﺎﺠﯾا ﺎﺑ ﺖﻣﺎﺠﺣ مﺎـﺠﻧا ﻊـﺿﻮﻣ رد ﯽـﻗوﺮﻋ دﺎـﺸﮔ يﺎﻫ
رﺎﺸﻓ دﺎﺠﯾا و نآ فاﺮﻃا و ﻪﯿﺣﺎﻧ يﺎﻫ ﺶﮐدﺎﺑ ﻞﯿﻟد ﻪﺑ ،هﺪﺷ ﺢﻄـﺳ ،ﺎـﻫ ﻪـﻠﺗ ﻦـﯾا رد هﺪـﻨﮑﻣ ﺖـﻟﺎﺣ و ﯽـﻔﻨﻣ ارLDL
ﺢﻄﺳ و ﺶﻫﺎﮐ ﯽﻣ ﺶﯾاﺰﻓا ار HDL
ﺪﻫد ) 20 .(
رادﺎـﻨﻌﻣ ﺶﻫﺎـﮐ ﺮـﺿﺎﺣ ﺶﻫوﮋـﭘ ﺮـﮕﯾد يﺎـﻫ ﻪﺘﻓﺎﯾ زا ) يزاﻮﻫ ﻦﯾﺮﻤﺗ هوﺮﮔ رد نژﻮﻨﯾﺮﺒﯿﻓ 13%
) ﺖـﻣﺎﺠﺣ و ( 6%
(
ﯽـﺴﻤﺷ تﺎـﻌﻟﺎﻄﻣ ﺎﺑ ﻪﮐ ﺖﺳا لﺮﺘﻨﮐ هوﺮﮔ ﻪﺑ ﺖﺒﺴﻧ و هداز
) نارﺎــﮑﻤﻫ 1399
)(
19 و ﻞــﮕﭼ ( ) نارﺎــﮑﻤﻫ
1399 )(
23 ،(
) نارﺎﮑﻤﻫ و رﻮﭙﺳﺎﺒﻋ 2018
)(
24 نارﺎﮑﻤﻫ و ﺖﺳوﺪﻧاﺮﯾا و (
) 2019 )(
25 ﺎـــﺑ و ﻮـــﺴﻤﻫ ( و ﺎـــﺳرﺎﭘ يﺮـــﯿﻣا تﺎـــﻌﻟﺎﻄﻣ
)نارﺎﮑﻤﻫ 1398 )(
26 ﯽﻣ ﻮـﺴﻤﻫﺎﻧ ( تﺎـﻨﯾﺮﻤﺗ .ﺪـﺷﺎﺑ
ﻢﻈﻨـﻣ
يزاﻮﻫ زا ﻖﯾﺮﻃ ﺶﻫﺎﮐ تﺎﮑﯾﺮﺤﺗ ﺶﻫﺎـﮐ ،ﯽـﻨﯿﻣاآ لﻮﮑﺗﺎﮐ
ﻦﯾﺎﮐﻮﺘﯿﺳ ﺎﻫ
ﻪﺑ صﻮـﺼﺧ ﻦﯿﮐﻮـﻟﺮﺘﻨﯾا
6 ﯽـﺷﺎﻧ زا ﺶﻫﺎـﮐ
،ﯽﺑﺮﭼ ﺖﻓﺎﺑ ﺶﯾاﺰﻓا
نﺎﯾﺮﺟ نﻮﺧ تﻼـﻀﻋ و ﺶﯾاﺰـﻓا ﯽـﻠﮐ
ﻢﺠﺣ ﺪﻧاﻮﺗ ﯽﻣ نﻮﺧ ﺐﺟﻮﻣ
ﺶﻫﺎﮐ ﺖـﻈﻠﻏ رد نژﻮـﻨﯾﺮﺒﯿﻓ
نﻮﺧ ددﺮﮔ 27) .(
ﯽﻠـﺻا رﻮﺘﮐﺎﻓ ﮏﯾ نژﻮﻨﯾﺮﺒﯿﻓ و
رد ﺮﺛﺆـﻣ
ﻪﻌﺳﻮﺗ ﺶﻫﺎـﮐ ،ﺖـﺳا ﯽﺒﻠﻗ تﻼﻤﺣ و زوﺮﻠﮑﺳوﺮﺗآ ي ﻦـﯾا
ﻪﻧﺎﺸﻧ ﺪﻧاﻮﺘﯿﻣ ﺰﯿﻧ لﺎﻣﺮﻧ ﻪﻨﻣاد رد لﻮﮑﻟﻮﻣ ﺮـﻄﺧ ﺶﻫﺎـﮐ ي
زوﺮﻠﮑــﺳوﺮﺗآ ﺪــﺷﺎﺑ
) 28 ( نژﻮــﻨﯾﺮﺒﯿﻓ . ﺎــﺑ سﻮــﮑﻌﻣ طﺎــﺒﺗرا
ﻪﻄﺑار وHDL ﯽﻗﺎﭼ ﺎﺑ ﯽﻤﯿﻘﺘﺴﻣ
، سﺮﺘـﺳا و LDL دراد
) 29 ﺟﻮﺗ ﺎﺑ و ( ﺮـﺿﺎﺣ ﻪـﻌﻟﺎﻄﻣ ﺞﯾﺎﺘﻧ ﻪﺑ ﻪ
زا ﯽـﮑﯾ ﻻﺎـﻤﺘﺣا
ﺶﻫﺎﮐ ﻞﯾﻻد نژﻮﻨﯾﺮﺒﯿﻓ حﻮﻄﺳ
، ناﺰـﯿﻣ ﺶﯾاﺰﻓا رد HDL
،ﻦﯿﻨﭽﻤﻫ.ﺪﺷﺎﺑ تﺎﻨﯾﺮﻤﺗ ﻪﺠﯿﺘﻧ هدﺮﮐ نﺎﯿﺑ ﻦﯿﻘﻘﺤﻣ
ﺪـﻧا ﻪـﮐ
ﺖﯿﻟﺎﻌﻓ ﺶﯾاﺰﻓا ﯽﮑﺗﺎﭙﻤﺳ ﯽﺒﺼﻋ ﻢﺘﺴﯿﺳ
ﻦﯿﻨﭽﻤﻫ و ﺮﯿﯿﻐﺗ
رد ﺮﯾدﺎﻘﻣ ﺰﯿﻧ ﯽﺑﺮﭼ ﺪـﻧراد ﺮﯿﺛﺎـﺗ نژﻮـﻨﯾﺮﺒﯿﻓ تاﺮﯿﯿﻐﺗ ﺮﺑ
و
نژﻮﻨﯾﺮﺒﯿﻓ ﺷ ﻦﯾﺮﺘﻬﺑ
تﻼﮑـﺸﻣ ﯽﻟﺎـﻤﺘﺣا ﯽﺑﺎـﯾزرا رد ﺺﺧﺎ
ﻘﻣ ﻪﮐ ﺖﺳا ﺮﻧوﺮﮐ قوﺮﻋ ﺮـﺑ ﯽـﺑﺮﭼ ﺮﯾدﺎ
ﻣ ﺮﯿﺛﺄـﺗ نآ ﯿ
ـﮕ دراﺬ
) 19 ﯽﻓﺮﻃ زا .(
ﻖـﯾﺮﻃ زا يزاﻮـﻫ ﻢﻈﻨـﻣ تﺎﻨﯾﺮﻤﺗ ﺶﯾاﺰـﻓا
ﻦﯿـﻨﭽﻤﻫ و تﻼـﻀﻋ نﻮـﺧ نﺎـﯾﺮﺟ و نﻮﺧ ﻢﺠﺣ ﺶﻫﺎـﮐ
ﺮﺤﺗ ﮑﯾ تﺎ ﯽﻨﯿﻣﻻﻮﮑﺗﺎﮐ )
27 ( و ﺰﺘﻨﺳ ناﺰﯿﻣ ﺶﻫﺎﮐ ﯽـﺸﺨﺑ
نژﻮـــــﻨﯾﺮﺒﯿﻓ )
Fractional Synthesis Rate
د ( ر
تﺪـﻣ ﯽﻧﻻﻮـﻃ تﺎﻨﯾﺮﻤﺗ ﯽﻣ
ﺖـﻈﻠﻏ ﺶﻫﺎـﮐ ﺐـﺟﻮﻣ ﺪـﻧاﻮﺗ
دﻮﺷ نﻮﺧ رد نژﻮﻨﯾﺮﺒﯿﻓ )
19 .(
ﺶﻫﺎﮐ ﺮﺿﺎﺣ ﻖﯿﻘﺤﺗ 6
هوﺮﮔ رد ار نژﻮﻨﯾﺮﺒﯿﻓ يﺪﺻرد
.داد نﺎـﺸﻧ ﺖﻣﺎﺠﺣ دﺎـﺑ
ﺐﺟﻮﻣ ﺶﮐ ا
ﺎﺠﯾ د ﺎﺸﻓ ر ﯽﻔﻨﻣ يور
د ﻮﯾ هرا آ ي ﺪﻧ و ﯽﻣﻮﯿﻠﺗ رآ ﻮﯾﺮﺗ ل ﺎﻫ و و ﻮﻧ ل ﺎﻫ ي ﺎﯿﺴﺑ ر ر ﺰﯾ
ﺪﺷ ﺖﺳﻮﭘ ﺢﻄﺳ و ه
ﻮﻔﻧ ذ ﺮﯾﺬﭘ ا و ي ﺎﺴﺗ د ع ﻮﯾ هرا ار يا
ا ﺰﻓ ا ﺶﯾ و هداد ﺎﺒﺟﻮﻣ ت ﺮﺧ جو ﻮﻨﯾﺮﺒﯿﻓ ار نژ ﺮﻓ ا ﯽﻣ ﻢﻫ .ﺪﻨﮐ
ﺲﭘ زا ﺎﺑ د ﺬﮔ ﺶﮐ وا يرا ﻪﯿﻟ ا ، ﺎﺠﯾ د ﺮﺧ شا ﺐﯾﺮﺨﺗ ﺐﺟﻮﻣ و
ﯽﮔﺪﯾﺮﺑ رآ ﺮﺗ لو ﺎﻫ و و ﻮﻧ يﺎـــــﻫ ل ﺪﺷ ﯽﮔﺮﯾﻮﻣ
ه ﻪﮐ ا زا ﻦﯾ
ﯽﺸﺨﺑ ﺰﯿﻧ ﻖﯾﺮﻃ زا
ﻮﻨﯾﺮﺒﯿﻓ نژ ﺎﺧ جر ﺪﺷ ه ﺎﺒﺟﻮﻣ ت ﺎﻫ ي
ﻞﯿﮑﺸﺗ ر ﻪﺘﺷ ﺎﻫ ي ﻦﯾﺮﺒﯿﻓ آ و ﺎﻏ ادا و ز ﻪﻣ ور ﺪﻧ ا ﺎﻘﻌﻧ و د ﻟ ﻪﺘﺨ
ﺪﺷ ن ﻮﺧ ار ن ﺮﻓ ا ﯽﻣ ﻢﻫ ) ﺪﻨﮐ 17،30 ﺶﻫﺎﮐ ﺚﻋﺎﺑ ﻪﺘﺨﻟ .(
ﻮﻨﯾﺮﺒﯿﻓ ﺢﻄﺳ نژ
ﺪﺷ ه ﻮﺧ ﻪﮐ د ﺐﺟﻮﻣ ا ﺰﻓ ا ﺎﻌﻓ ﺶﯾ ل ﺪﻨﻨﮐ ه
ي ﻮﻨﯿﻤﺳﻼﭘ نژ ) ﯽﺘﻓﺎﺑ ﯽــــﻣ (TPA
ﺮﮔ ا .دد ﺰﻓ ا ﺶﯾ TPA
ﺐﺒﺳ ا ﺰﻓ ا ﻮﻨﯿﻤﺳﻼﭘ ﺶﯾ ا و نژ
ﻦﯾ ا ﺎﻌﻓ ﺚﻋﺎﺑ ﺮﻣ ل
ﺎﺳ يز
ﯽﻣ ﻦﯿﻤﺳﻼﭘ ﺮﮔ
ﯽــــﻣ .دد ﻢﯿﻧاد
ﻮﻨﻋ ﻪﺑ ﻦﯿﻤﺳﻼﭘ ﻪﮐ نا
ﮏﯾ
ﺪﺿ ا ﺎﻘﻌﻧ د ﺪﺷ ﻞﺣ ﺚﻋﺎﺑ ن
ﻪﺘﺨﻟ ﺎﻫ ي ﻮﺧ اد رد ن ﻞﺧ
و
ﺎﺧ جر ﺮﻋ قو ﯽﻣ .دﻮــــﺷ ﺖﺳﺎﻣ ﺎﻫﻞﺳ و ﺎﺑ وز ﻞﯿﻓ ﺰﯿﻧ ﺎﻫ ﻪــــﮐ
ﯽﯾﺰﺟ زا ﻢﺘﺴﯿﺳ ا ﻮﺴﺤﻣ ﯽﻨﻤﯾ ب
ﯽﻣ ﻧﻮﺷ د ﺎﻌﻓ ل ﺪﺷ و ه ﺮﺑ
ﺎﭙﻫ ﺢﺷﺮﺗ ر
ﯽﻣ ﻦﯾ ا ﺰﻓ ا ﺪﻨﯾ و ﻊﻤﺟ ﻞﺻﺎﺣ ا
ﺰﻓ ا ﺎﭙﻫ ﺶﯾ ر ﺰﯿﻧ ﻦﯾ
ﺐﯾﺮﺿ ﺶﻫﺎﮐ ا
ﺎﻘﻌﻧ يد ﻮﺧ ،ن ﻢﻀﻫ و يدﻮﺑﺎــــــﻧ ﻪﺘﺨﻟ
ﺎﻫ ي
ﯽﻧﻮﺧ رد ﻮﯿﻠﯿﻣ ن ﺮﯾﻮﻣ ﺎﻫ ر گ ﺰﯾ ﻋ و ﺢﻄﺳ رد و ﺎـﻫ ﺖﻓﺎﺑ ﻖﻤ
روﺎـﺠﻣ يﺎـﻫ ماﺪـﻧا و ﺖﻓﺎﺑ هﮋﯾو ﻪﺑ ﺎﻫ ماﺪﻧا ﺖﻣﺎﺠﺣ ﻊﺿﻮﻣ
ﯽﻣ ) ﺪﺷﺎﺑ 30
، 17،14 .(
ﺎﺘﻧ ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ ﯾ
ﺞ ﺶﻫوﮋﭘ ﺎﻫ ي ﺺﺨـﺸﻣ ﻪـﺘﻓﺮﮔ ترﻮﺻ
ﺖﺳا هﺪﺷ ﺮﺛﻮـﻣ ﯽﻠﻣاﻮﻋ يزاﻮﻫ ﯽﻧﺪﺑ ﺖﯿﻟﺎﻌﻓ و ﺖﻣﺎﺠﺣ ﻪﮐ
و نژﻮـﻨﯾﺮﺒﯿﻓ ﺢﻄﺳ ﺶﻫﺎﮐ ﺶﯾاﺰـﻓا و نژﻮـﻨﯾﺮﺒﯿﻓ وLDL
HDL ﯽﻣ ﻪﺴﺋﺎﯾ نﺎﻧز رد ا ﺎﻣا ﺪﺷﺎﺑ
ﯽﻣ شزرو ﻻﺎﻤﺘﺣ ﺪـﻧاﻮﺗ
ﺪـﯿﭙﯿﻟ و نژﻮـﻨﯾﺮﺒﯿﻓ ﺮـﺑ يﺮﺘﻬﺑ رﺎﺛآ ﺖﻣﺎﺠﺣ ﻪﺑ ﺖﺒﺴﻧ يﺎﻫ
ﯽﺒﻠﻗ يرﺎﻤﯿﺑ يازﺮﻄﺧ ﻞﻣاﻮﻋ ﻦﯾﺮﺘﻤﻬﻣ ﻪﻠﻤﺟ زا ﻪﮐ ﯽﻧﻮﺧ -
.ﺪﺷﺎﺑ ﻪﺘﺷاد ،ﺪﻨﺘﺴﻫ ﻦﯿﯾاﺮﺷ ﺐﻠﺼﺗ و ﯽﻗوﺮﻋ
ﺶﻫوﮋﭘ ﺮﺿﺎﺣ ﯽﯾﺎﻫ ﺖﯾدوﺪﺤﻣ ﺎﺑ هاﺮـﻤﻫ
دﻮـﺑ ﻪـﮐ مزﻻ
ﺖﺳا درﻮﻣ ﻪﺟﻮﺗ راﺮﻗ ﺪﻧﺮﯿﮔ . ﻪـﻠﻤﺟ زا مﺪـﻋ
لﺮـﺘﻨﮐ ﻖـﯿﻗد
ﻪﯾﺬﻐﺗ ﺮﮐذ ار
؛دﺮﮐ ﻦﯾاﺮﺑﺎﻨﺑ ﻪﯿـﺻﻮﺗ ﯽـﻣ دﻮـﺷ رد ﺶﻫوﮋـﭘ
يﺎﻫ ﺮﮕﯾد ﻦﯾا ﺰﯿﻧ ﻞﻣاﻮﻋ ﺎﺗ
ﺪﺣ نﺎﮑﻣا لﺮﺘﻨﮐ ﺪﻧﻮﺷ .
رﺪﻗ و ﺮﮑﺸﺗ ﯽﻧاد
نﺎﮔﺪﻨﺴﯾﻮﻧ ﻦﯾا
ﻪﻟﺎﻘﻣ ﺮﺑ دﻮﺧ مزﻻ ﯽﻣ ﺪﻨﻧاد ﻪﮐ زا ﻪـﯿﻠﮐ
قﻮــﻓ ﺶﻫوﮋــﭘ رد نﺎﮔﺪــﻨﻨﮐ ﺖﮐﺮــﺷ و ﻦﯿــﺒﻠﻃواد و
ﺮﯾﺪــﻣ
هرادا ﺶﻫوﮋﭘ ﻞﮐ
ﻢﻗ نﺎﺘﺳا ﯽﻧﺪﺑ ﺖﯿﺑﺮﺗ ﯽﻧادرﺪـﻗ
و ﺮﮑـﺸﺗ
ﻪﺑ ﻞﻤﻋ .ﺪﻧروآ
قﻼﺧاﺪﮐ : IR.QOM.REC.1399.020
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Comparison of aerobic exercise and cupping methods on serum levels of fibrinogen, LDL and HDL as cardiovascular disease factors in
postmenopausal women
Delshad AU¹*, Dashti MS², Akbari S³, Azizi Alavicheh Z⁴
1.Assistant Professor, Department of Sports Science, Faculty of Literature and Humanities, Qom University, Iran, [email protected]
2.Master of Sports Physiology, Department of Sports Sciences, Faculty of Literature and Humanities, Qom University, Iran
Received: 2022/04/18 Accepted: 2022/05/11
Abstract
Background: Menopause is a clinically significant period of time characterized by changes in ovarian hormone, vasomotor symptoms, and an increased risk of cardiovascular disease (CVD). One of the main causes of heart attacks is changes and imbalance of the homeostasis system. Sedentary lifestyle and aging also have adverse effects on the homeostasis system. One of the treatment methods that has been used for many years in the treatment of many diseases is Iranian-Islamic medicine. Therefore, in this study, the effect of cupping and aerobic exercise on LDL, HDL and fibrinogen was investigated Materials and Methods: A total of 30 inactive postmenopausal women with an age range of 50 to 65 participated in this quasi-experimental study. Participants were randomly divided into three groups: aerobic exercise, cupping therapy, and control group. Aerobic exercises with an intensity of 50 to 75% of heart rate reserve were performed three times a week for 6 weeks and the cupping group was cupped in the third week. Blood samples were taken to measure fibrinogen, LDL, and HDL before the start of the training period and 48 hours after the end of the last training session.
Then, an analysis of covariance was used for intergroup comparisons. Also, the pre- and post-test were analyzed using paired t-test at a significance level of <0.05.
Results: Aerobic exercise and cupping showed a significant decrease in fibrinogen (P = 0.04) and LDL (P = 0.001) and an increase in LDH (P = 0.003). Paired t-test results showed a significant decrease in fibrinogen, LDL and HDL post-test compared to pre-intervention post-test.
Conclusion: Cupping therapy and aerobic physical activity are effective factors in reducing the levels of fibrinogen and LDL and increasing HDL in postmenopausal women. According to the results, exercise may have better effects on decreasing fibrinogen and blood lipids, as the most important risk factors for cardiovascular disease and atherosclerosis, compared to cupping therapy.
Keywords: Aerobic Exercise, Cupping, Fibrinogen, LDH, LDL.
*Citation: Delshad A, Dashti MS, Akbari S, Azizi Alavicheh Z. Comparison of aerobic exercise and cupping methods on serum levels of fibrinogen, LDL and HDL as cardiovascular disease factors in postmenopausal women. Yafte. 2022;
24(1):47-57.