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9 @ U- 6 6. A
7 C8A :C- C&'
8CC! CCX CC3 UCC )
24 .(
CC 7CC 7 CC&j8A
B B Y&. O' A " CF ' C+ 9 C4. :- &'
f8' )- " 8 - &'
) 11 .(
C@
CT C
:;
f8' " F ' + B Y&. :- :' C&'
7 = z . M RO!
C " 8C!
C - .
" ' + " j8A " 8! @+8, -
) 8 .(
:CL
9 :;
• . 8, :C' C! C&E A ' C! C+H
" F &E M RO! " p J - v
CT 7C
:' ! _ _
CA hCI :C;
C-
9 +! ! = M 5 3 7 = :- O= A
" F > &E &A ' C -
C " C - 7 C&j8A v
:; ! C> :C- | C- " i ' C! :C- N&
SREBP
)
Sterol Regulatory Element Binding
Protein
( 8C! 5 C3 MA C' - 7 ` v
7 C= :C- C 6 CO1- :C- CN& CO' A >
) 25 .(
5 C3 :C' C! C _ C 7 &j8A
)• <
:;
9 +!
A
O'
C g CA
CC) CC=' CC=' H CC! UCC OE " 5 CC )h
? CC. ' . 8CC=
7. CC' )- CC<
CC 9 CC' .
)
" =' A 7 T C -
) 26 ( `C v
Y :-
! MA C' '`C C X :4 d
B CC CCA
ALT
3€CC AST
CC- CC . MA gCCH W CC)
" CC@8A & CC=
) 8 ( 5 CC m. :CC&
CC-ALT
BCA CX MA gH CT 7C C- CF
:C&
5 m.
BA X MA gH -AST
F .
"
C A
p CJ 8A :- & 7 8. :)<A 1L :' ' _ :CC;
B CC MA CCC' ROCC!
CCCA
AST ALT
: 8 C C- :C- )CO A v
C - MA gCH C
@ o. :N ) 7 " @8A )
27 .(
" @8A -
A gH ' <)! ) 6 7 8. U@. H F M X MA gH :N ) - 5 <. +I U 9 8) :'
- . 4 X MA gH <)C! A A
! .
! B)= ! - 7 8. Q :' A A
N " -
! 5 <) &&' .
) C6 7 C8. * N
U :- CO1- C CA 7 C8. :- O= ? - 5
B A
AST
Y+a MA ' D ' &' ALT
" F C
) 23 .(
UC‚ C 5 C& 8. 7 C&j8A
M C C =' N U :- ) 6 7 8.
9 @ .
" :+8 A +C! C a :C- CA
:- " ! R ! RT -
" - ƒ+)K A
M RO!
&4 B C C! b d!
CO' CA
) 28 .(
B b d! :' " X MA gH CA
AST
9 C)&' C :C- OC= ) 6)! 7 8. ALT
MA C' 7C T 7 - :) MA ' C&4
C=
.
4 6)! 5 &+- A C . :' )
C 4 " C - ! A )! s P ) - "
B A
ALT
:C C- C ! ` 3o.AST
4 Q 7 sC P C C . :- ) - A
CT A )!
) 27 .(
CT C- " C= " C-
:+n, " @ + :- ) 6)! 7 8.
C)8' 8! H ' +
C! DCO& :C- - 5 A :+n, ! @) CA
:)=- ) - i L .
C& p CJ Q X 7
8C! :C- @ + = p h U :- i L ! C+ CF 7C :C' C- A F " ! =' )- :F L
C m. * C, z X . - C&4
B C CA
ALT
CC ) 6)CC! CC CC 4 * CCN CC4-AST
C CX :4 d ) 6)! 7 8.
C - ) 29 .(
p CP
MA gH W ) F - % ! - :C- C- :C- )- A
}, - ? P " 5 - g 6 8 -
C1T 7 C8A :C- C&' H 7 = :- O= ) - ! 7@8
? P "
7 C8. :C- ~! H - . CA
- A
) 30 .(
7 C8. :C+F X MA gH
B MA ' }, - 5 CI C :C' C O' A
C&4 W C) :C)<A MC M - :- 5 & 8. : - B A
ALT
! :- AST
. MA gH
" @8A )
31 ( " C@8A
) 32 ( C
' X MA gH :N ) .
MA gCH W ) p F -
MA gH F - W ) X B C M ' A
CA
ALT
4 3 AST
! A
. 9 C‚ -
~ H CF :C4 d " .
:C' C ' _ C 30
OC! :C+H 7)C 7 CH ? C- :6 E C 4 M C R
B A
ALT
C AST
) 33 .(
C- p )CF C+,
4 5 Q X MA gH :N ) -
B " RO! :'
C . CO' A
. ATP
" B C C ) : Y % ! -
! 7@8 8! H ) ! a " - :- 9 +!
C
B CA
ALT
C C " CF " :C-AST
) 8 .(
- 8 - 7 &j8A C CX MA gCH A
W ) p )F - 1 T . -
) 34 .(
W ) 7 &j8A
9 p J :' " X MA gH :;
C1&. :-
3
&4 d+a -
ALT
_ AST
A hCI )-
.
" >' " @8A )
35 ( :C' C ' _ C
p J :;
B C zdC! M C ROC! C! 7@8
O' R ! a 8= @ :+ ! :-ALT
.
"
A
B :' "
C " - " M s P ALT
M
! O' R ! T M 7 - .
7 &j8A C&
C@8A "
) 36 ( p CJ :C' C " C
:;
`Ca p J M " - 5 " - "
&' . `C 3 * C, UC ? CX :C4 d
9 p J :C;
CY+a C-
ALT
_ C AST
CA
)- hI
. C sC 6h. . '
- 9 C CA :C- C - " J 7C C!
:+GC=
MA gH - 1& H " &, :- . C4- CA
:) Y .
h A X :4 d C
" C.
. * , :- 9 C)&' J ' "
CC R CC! " CC _ CC
CCA * CC &A hCCI
T * , 7 &j8A " " )!
5 J- 5
@.
8 .
" H :N ) C
CX :C4 d :C'
9 p CJ - 8A ) 6)! 7 8. :)<A M :C;
MA C' + C4. 5 3
ALT
_ C AST
CA
C- :- )O hI C
C - }C, - :C' CP :C-
) - MA ' 6)C! 7 8. :- O= ALT
p CJ )
9 :;
MA ' 7 &j8A 1&. :- :C- OC= AST
1&. :- ) 6)! 7 8.
. :C- :T . - 7
X MA gH W ) MA ' 1T :' ' : I . " .
R CC!
CCO' CCA
ALT
CC- CC8 - AST
9 p CJ C- C8A BY&C ) 6)! 5 & 8.
:C;
<)!
.
eQ.
" $ :
#
fCC8' CCA CC& MA gCCH CC 4 CC&4 CE @C . C C C!
.
References
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The Interactional Effects of Endurance Training and Aloe Vera Gel on Alanine Aminotransferase and Aspartate Aminotransferase levels in Diabetic Rats
Hosseini SA*1, Nezafat Absardi M2, Shadmehri S3, Salehi O2, Hajisadeghi H4
1. Associat Proffessor, Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran, [email protected].
2. MSc of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
3. Assistant Proffessor, Department of Physical Education and Sport Sciences, Yadegar- e-Imam Khomeini Branch, Islamic Azad University, Tehran, Iran.
4. MScof Sport Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Received: 7 Jan 2018 Accepted: 7 Feb 2018
Abstract
Background: Exercise and nutrition are two basic foundations in the control of increased levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in diabetes disease. The aim of the present study was to review the interactional effects of endurance training and aloe vera gel on ALT and AST levels in diabetic rats.
Materials and Methods: Forty five diabetic rats were selected and divided into 5 groups of 9 rats (1) first week control, (2) sixth week control, (3) endurance training, (4) aloe vera, (5) endurance training with aloe vera. Also for review of the effects of diabetes induction on ALT and AST, 18 rats were divided into two groups of (6) first week control, and (7) sixth week control. Groups 3 and 5 ran on treadmills for 6 weeks, 3 sessions per week and 20 minutes per session. Groups 4 and 5 received 100 mg/kg aloe vera gel. For statistical analysis of the data one way ANOVA and tukey post hoc tests (p≤0.05) were used.
Results: Diabetes induction has a significant effect on the increase of ALT (p=0.04): endurance training together with aloe vera gel has a significant effect on the reduction of ALT and AST levels (p=0.001); endurance training with aloe vera gel, together with endurance training and aloe vera gel consumption has more effect on reduction of ALT (p=0.001). Endurance exercise together with Aloe vera gel has a greater effect on AST reduction than endurance training alone (P = 0.04).
Conclusion: 6 weeks of endurance training and aloe vera gel have interactional effects on the improvement of ALT and AST levels in diabetic rats.
Keywords: Endurance Training, Aloe vera, Alanine Aminotransferase, Aspartate Aminotransferase, Diabetes.
*Citation: Hosseini SA, Nezafat Absardi M, Shadmehri S, Salehi O, Hajisadeghi H. The Interactional Effects of Endurance Training and Aloe Vera Gel on Alanine Aminotransferase and Aspartate Aminotransferase levels in Diabetic Rats. Yafte. 2018; 20(1):99-111.
