저작자표시-비영리-변경금지 2.0 대한민국 이용자는 아래의 조건을 따르는 경우에 한하여 자유롭게
l 이 저작물을 복제, 배포, 전송, 전시, 공연 및 방송할 수 있습니다. 다음과 같은 조건을 따라야 합니다:
l 귀하는, 이 저작물의 재이용이나 배포의 경우, 이 저작물에 적용된 이용허락조건 을 명확하게 나타내어야 합니다.
l 저작권자로부터 별도의 허가를 받으면 이러한 조건들은 적용되지 않습니다.
저작권법에 따른 이용자의 권리는 위의 내용에 의하여 영향을 받지 않습니다. 이것은 이용허락규약(Legal Code)을 이해하기 쉽게 요약한 것입니다.
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저작자표시. 귀하는 원저작자를 표시하여야 합니다.
비영리. 귀하는 이 저작물을 영리 목적으로 이용할 수 없습니다.
변경금지. 귀하는 이 저작물을 개작, 변형 또는 가공할 수 없습니다.
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0 10 20 30 40
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0 10 20 30 40
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ᔲ㕚ᕎ⹚ᜮ# ⧤⧲1# ₲Ἆ# Ⱂᆏ⮞⧻⩪▶# ႚⰿ# Ⲛ㨇○Ⰾ# ᕈ⧲៲#O1#vdnhl#NRN ᜮ# sK#6 ᆖ#
7 ᳶ# ⴊⲢ㧶# PUV# ⹚⩪▶ᡞ# ႚⰿ# ᕈ⯚# ⸷❷᷺⯞# ⪚1# #
→# ❾㩲# ᅊᆖ⩪▶⫚# ႳⰎ# ᕈ⯚# sK㫲ᅗ⩪▶# ⮺╊ቺⰎ# ⸷❷㧶ᜮ# ►㨣⪊ሆႚ# ᅺᢲ
⩢1# ជ⯲# ⅚⩪▶√㗊# ∞Ṇ㧶#O1# vdolydulxv# IF446⯚# sK# 518⯲# PUV# ⹚⩪# 8# orj#
FIX2pOᳶ# ⲫⴟ㧲ᅺ# 7# ❶႞# 㭞⩪# 9# orj# FIX2pOᳶ# ⸷❷㧲⪚ᅺ/# ;# ❶႞# 㭞⩪ᜮ# ;# orj#
FIX2pOᳶ# ⸷❷㧲⪚# ^64`1# ❺╷⧞# ⅚⩪▶√㗊# ∞Ṇ㧶#O1#dflgrskloxv/#O1#exojdulfxv/#
O1# ukdpqrvxv/# ኒṆᅺ#V1# wkhuprsklohv# ⮺╊ቺ⯚# sK# 6⯲# ᕈ⯚# ╊○# 㫲ᅗ⩪▶ᡞ# ⸷❷ 㧶ᅺ# ᅺᢲ⩢# ^65`1#
㧲⹚Ṧ# ⮺╊ቺⰎ# ᕈ⯚# sK# 㫲ᅗ⩪▶# ╆ἒ㧶ᜮ# ᅊᆖᡞ# ᅺᢲ⩢1# ❺╷⧞⯲# ⅚⯖ᳶ
√㗊# ∞Ṇ㧶#S1# dflglodfwlfl# JPE:663Ḗ# 㡃❺⯞# 㢆㨂㧲⪆# sK# 6# ⯖ᳶ# ⴊⲢ㧶# PUV#
⹚⩪# 913佴43;#FIX2po⯲# ᘧᡞᳶ# ⲫⴟ㧲⪆# 5# ❶႞# ᘒ㈶❶㕂# ᅊᆖ# ⩪▶# ;1:佴437#
FIX2pO⯖ᳶ# Ⴊ☦㧲⪚# ^46`1# ᪪㧶# sK# 6⯖ᳶ# ⴊⲢ㧶# Ⱂᆏ⮞⧻⩪# <# orj# FIX2pO# ᘧ ᡞḖ# ⲫⴟ❶㎶# 6# ❶႞# ᘒ㈶# ❶㕂# ᅊᆖ/#Odfwredflooxv#sodqwduxp#SRP53⯚# ቺ# ⚲Ḗ# ኒ រᳶ# ⮺⹚㧲⪚⹚Ṧ/#Odfwredflooxv# ihuphqwxp# I4⯚# 918# orj# FIX2pOᳶ# Ⴊ☦㧲⪚#
^58`1# #
# #
# I
Ilj1#51#Jurzwk#fxuyh#ri#h{shulphqwdo#ODE#lq#sK#6#PUV1#O1#sdudfdvhl#FK;;+侘,/#O1#
sodqwduxp# SK6D+侗,/# O1# ihuphqwxp# SK6E+侔,/# O1# ihuphqwxp# HSV55+侕,/# O1#
ukdpqrvxv#47+侑,/#O1#vdnhl#NRN#+侍,/#O1#dflgrskloxv#NIUL#483+侖,/#O1#ukdpqrvxv# NFWF#656:+侐,/#O1#sodqwduxp#NIUL#:3;+儸,1# #
Gdwd#duh#h{suhvvhg#dv#phdq# 佳# vwdqgdug#ghyldwlrq1##
# ##
$EVRUEDQFHQP
+RXUV
&+ 3+$ 3+% (36 VDNHL DFLGR UKDP SODQ
# I
Ilj1#61#Jurzwk#fxuyh#ri#h{shulphqwdo#ODE#lq#sK#7#PUV1#O1#sdudfdvhl#FK;;+侘,/#O1#
sodqwduxp# SK6D+侗,/# O1# ihuphqwxp# SK6E+侔,/# O1# ihuphqwxp# HSV55+侕,/# O1#
ukdpqrvxv#47+侑,/#O1#vdnhl#NRN#+侍,/#O1#dflgrskloxv#NIUL#483+侖,/#O1#ukdpqrvxv# NFWF#656:+侐,/#O1#sodqwduxp#NIUL#:3;+儸,1# #
Gdwd#duh#h{suhvvhg#dv#phdq# 佳# vwdqgdug#ghyldwlrq11# #
$EVRUEDQFHQP
+RXUV
&+ 3+$ 3+% (36 VDNHL DFLGR UKDP SODQ
6151# ⮺╊ቺ# ⨫# ╛ᦋ⧻⯲#K1#s|orul# 㨇ቺ# 㭂ᆖ# # 615141# ⮺╊ቺ# ⨫# ╛ᦋ⧻⯲#K1#s|orul# ⸷❷# ⩏Ⲷ#
61514141#Vrolg#lqklelwlrq#dvvd|# ᅊᆖ#
53# ❶႞# ⨫㧶# ⮺╊ቺ⯲# ⨫# ╛ᦋ⧻⯞# Sdshu#glvf⩪# ㄲṆ㧲⪆#K1#s|orul# ᅺㅎ⹚
⩪▶# ᆚナ㧶# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊᜮ# Wdeoh# 7⩪# Ⲷ❶㧲⪚1# រ√∞⯲# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊ ᜮ# ⨫# ╛ᦋ⧻⯲# sKႚ# ᕈ⧞⩪# ᰖ# ⸷ႚ㧲⪚1#O1#sdudfdvhl#FK;;/#O1# sodqwduxp#
SK6D/#O1#ukdpqrvxv#NFWF#656:/#O1#ukdpqrvxv#47⯲# ⨫# ╛ᦋ⧻⯚# sKḖ# ⴊⲢ㧲⹚#
⧤⧲⯞# ᧦# ;#pp⯲# ╷⮻⩏Ⲷ㫲⯞# ᆚナ㧺# ⚲# Ⱒ⩢1# ⨫# ╛ᦋ⧻⯞# sK#715ᳶ# ⴊⲢ㧲⪚
⯞# ᧦/# រ√∞⯲# ᅗ⭊# ╷⮻⩏Ⲷ㫲⯞# ᆚナ㧺# ⚲# ⩠⩢⹚Ṧ/#O1# ihuphqwxp#SK6E/#O1#
sodqwduxp#NIUL#:3;#/#O1#ukdpqrvxv#NFWF# 656:/#O1#ihuphqwxp#HSV55⩪▶ᜮ# sK#
715ᳶ# ⴊⲢ㨢⯦⩪ᡞ# ∢ሆ㧲ᅺ# 9180:# ppⲯᡞ⯲# ╷⮻⩏Ⲷ㫲⯞# ᆚナ㧺# ⚲# Ⱒ⩢1# 㧲⹚
Ṧ# sK# :ዦ⹚# ⴊⲢ㧲⪚⯞# ᧦⩪ᜮ# ὂ# ⨫# ╛ᦋ⧻⩪▶# ╷⮻⩏Ⲷ㫲⯞# ᆚナ㧺# ⚲# ⩠⩢
1#
►㨣⪊ሆ⩪▶#Odfwredflooxv#55# ⴟ/#vwuhswrfrffl#:# ⴟ/#elilgredfwhuld#49# ⴟ⯲# ⨫#
╛ᦋ⧻⯞# sK#717# ᳶ# ⲯ㧲⪆/#43#pp#sdshu#glvf⯖ᳶ#K1#s|orul⯲# 㨇ቺ㫶○⯞# ㊻ⲯ㧶#
ᅊᆖ/# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊᜮ# 4404;# pp⯖ᳶ# ⨫㨢1# 㝓㰢# Odfwredflooxv# jdvvhul# PN036# ቺⶖႚ# ႚⰿ# ㍾ᰚ# ╷⮻⩏Ⲷ㫲⯞# ᔲ㕚ᕎ⩢1# ᪪㧶/# 57# ❶႞Ṣ# ╷⮻⩏Ⲷ㫲
⯞# ㊻ⲯ㧶# ᅊᆖ# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊႚ# Ⴊ☦㧲ᜮ# ᅗ㨿⯞# ᯞ⩢ᜮ᠊/# →# ⪊ሆ⩪▶ᜮ#K1#
s|orulႚ# ⫞Ⲟ㰢# Ⱚᰚ# 㭞Ⱂ# 6# Ⱆ# 㭞⩪# ㊻ⲯ⯞# 㨢⯖⁚ᳶ# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊႚ# ⋞ᇪⲛ#
Ⱛ⯞# ᄝⰎᰖᅺ# ㈮㊻ᢶ# ^45`1# ᪪㧶# ᡳⰖ㧶# sK⩪▶ᡞ# Ḓ# ╷⮻⩏Ⲷ㫲⯲# 㔆ዊḖ# ᆚナ 㧺# ⚲# Ⱒ⩢⯖⁚ᳶ/# Ⰾᜮ# ⮺╊ቺ⯲# ⨫# ╛ᦋ⧻⯲# ᕈ⯚# sK⯲# ⯲㧶# ⪛㨿Ⰾᰖዊᜮ# ╷
○ᢶ# ╊⯲# ⴟᷲ⫚# 㨇ቺ○# ῖ⩪# ⯲㧶# ᄝⰎᰖ# ㈮㊻㧺# ⚲# Ⱒ1# ❺╷⧞⯲# ⅚⯖ᳶ√㗊#
∞Ṇ㧶#S1# dflglodfwlfl# JPE:663# ⨫⧻⯖ᳶ# 㨣㧶# ⪊ሆ⩪▶ᡞ# Ⲱ╊# Ⰾ⬒⯲# Ḓ# 㨇 ቺ○# ῖⰎ# ⮺╊ቺ# ⨫# ╛ᦋ⧻# ᕎ⩪# ⴎⱆ㧶ᜮ# ᄝ⯞# ₷㪮# ^46`1#
W
Wdeoh#71#Dqwledfwhuldo#hiihfw#ri#fhoo#iuhh#vxshuqdwdqw#ri#ODE#djdlqvw#K1#s|orul#e|#glvf#
phwkrg#
d,#Qr#lqklelwlrq#
-#9pp#eodqn#sdshu#glvf#zdv#xvhg#
#
Edfwhuldo#vwudlq# Ilqdo#sK#ri#
vxshuqdwdqw#
Fohdu#}rqh#gldphwhu#phdvxuhg+pp,#-#
zlwkrxw#sK#
dgmxvwphqw#
sK#dgmxvwhg#wr#
715#
sK#dgmxvwhg#wr#
:#
O1#sdudfdvhl#FK;;# 61<8# ;# # 0d,# 0#
O1#sodqwduxp#SK6D# 61;7# ;# 0# 0#
O1#ihuphqwxp#SK6E# 7153# :# :# 0#
O1#sodqwduxp#NIUL#
:3;# 61<4# :# 918# 0#
O1#ukdpqrvxv#NFWF#
656:# 61:7# ;# 918# 0#
O1#dflgrskloxv#NIUL#
483# 61<4# :# 0# 0#
O1#ihuphqwxp#HSV55# 7153# 918# 918# 0#
O1#ukdpqrvxv#47# 61:8# ;# 0# 0#
O1#vdnhl#NRN# 61<<# :# 0# 0#
61614151#Oltxlg#lqklelwlrq#dvvd|# ᅊᆖ# #
K1# s|orul⩪# sK# 715ᳶ# ⴊⲢ㧶# ⨫# ╛ᦋ⧻⯞# 4(/# 8(# ㅂႚ㧲⪚⯞# ᧦⫚# ㅂႚ㧲⹚# ⧤
⧲⯞# ᧦⯲# ╷ⰿ# ᅻ►⯚# ⯦ᆖ# Ⴓ# +Ilj1# 7,1# ⨫# ╛ᦋ⧻⯞# 4(# ᖽ⯚# ᄝᆖ# រⴊሊ⯞#
⋞ᇪ㧲⪚⯞# ᧦# ⮺⯲ⲛⰒ# ヂⰎႚ# ⩠⩢⹚Ṧ/# 8(Ḗ# ㅂႚ㧲⪚⯞# ᧦#K1# s|orul⯲# ⸷❷⯞# ⮺
⯲ⲛ⯖ᳶ# ⩏Ⲷ㧲⪚# +S?3138,1# ⮺╊ቺ# ⨫# ╛ᦋ⧻⯞# ㅂႚ㧲⹚# ⧤ᅺ# Euxfhood# eurwk#
ᕎ⩪▶# 㔾⭎#K1# s|orul⯲# 㯻ᆫᡞᜮ# 6# Ⱆ# 㭞# RG933Ⰾ# 3⩪▶√㗊# 316ዦ⹚# ⸷ႚ㧲⪚⯖ᔲ/#
⮺╊ቺ# ⨫# ╛ᦋ⧻⯞# 8(# ㅂႚ㧶# ᄝ⯚# រ√∞# RG933Ⰾ# 6# Ⱆ# 㭞⩪ᡞ# ⸷ႚ㧲⹚# ⧤⧲1#
Ⰾᜮ# ⮺╊ቺ⯲# ⨫# ╛ᦋ⧻Ⰾ#K1#s|orul# ⸷❷⯞# Ⲛ㨎㧲ᜮ# ᄝ⯞# ⪆1#
# ⮺╊ቺ⯚# Ⲱ╊/# គ♞⹚╊/# ㆢ╊/# ᆖ╊㫮⚲☦/# ₯㗦Ṇ⪾❺# ᦋ⯞# ╷○㧲Ἂ# Ⰾᲆ㧶#
ῖ⯚#K1#s|orul⯲# ╷⮻⯞# ⩏Ⲷ㧲ᜮ# ᄝ⯖ᳶ# ᅺᢲ⩎Ⱒ1# 㝓㰢# Ⲱ╊/# ㆢ╊/# ⪖╊# ᦋⰎ#
ᘧᡞ⩪# ᰖ# sK Ḗ# ᕈ㈮⩎# K1# s|orul⯲# ╷⮻⯞# ⩏Ⲷ㧲ᜮ# ᄝ⯖ᳶ# ⧦ᲾⳒⰢ⯖Ἂ/# Ⲱ╊Ⰾ#
ႚⰿ# ᘬ⯚# ⩏Ⲷ# 㫶○⯞# ᔲ㕚ᕎ⩢ᅺ# ᅺᢲ⩎Ⱒ# ^66`1# Ⰾ# ᧦/# 㨇ቺ㫶○⯚# ⮺╊ቺⰎ#
╷╊㧶# ⮺ዊ╊⯲# ⨫# ⮺ዊ╊⯲# ⴟᷲ⫚# 㨎Ṇ# ⮺῎⩪# ᰖ# ឆᰖᅺ# ⧦ᲾⳒ# Ⱒ1#
⮞⯲# ╊○# 㫲ᅗ⩪▶# ⨗╊Ⱂ# Ⲱ╊⯚# ⋞㨎Ṇ㪯⯖ᳶ# ⴎⱆ㧲ዊ# ᧦ῒ⩪# K1# s|orul ⯲#
◒㢆ṣ⯞# ✗ᄦ# 㙏ᆖ㧲⪆/# ◒㢆# sK ⩪# ⹛ⲫⲛ⯖ᳶ# Ⱛ⭃㨎#K1# s|orul ⩪# # ႯᲿ㧶#
ᡟ○⪛㨿⯞# ₒ㋺# ᄝⰎᰖᅺ# ᅺ㧲⪚# ^67`# Ⰾ⬒⩪ᡞ#Odfwredflooxv# uhxwhul# DWFF#
88:63 ᜮ# uhxwhulq/#Odfwredflooxv# dflgrskloxv# FUO# 96< ᜮ# dxwro|vlq ⯞# ∞⋞㧲⪆#K1#
s|orul ⯲# ⸷❷⯞# ⩏Ⲷ㧶ᅺ# ᅺᢲ⩢# ^48`1# ❺╷⧞# ⅚⯖ᳶ√㗊# ∞Ṇ㧶#
Hqwhurfrffxv# idhflxp# WP6< ⯲# 53 ❶႞# ⨫㧶# ╛ᦋ⧻⯞# K1# s|orul ⩪# 7 ❶႞#
ㄲṆ㧲⪚⯞# ᧦/# 708# orj# FIX2pO# ⯲# ╷ቺ# ⚲# Ⴊ☦Ḗ# ᆚ㧺# ⚲# Ⱒ⩢1# ኒṆᅺ# Ⰾᄝ⯲#
⨫# ╛ᦋ⧻⩪# ⪎ㄲṆ/# គ∞㨎㭂☦# ㄲṆḖ# 㧲⪚⯞# ᧦⩪ᡞ# K1# s|orul ⩏Ⲷ# 㭂ᆖḖ#
⮺⹚㧲⪚⯖Ἂ/# Ⰾᜮ# 㨎ន# ⮺╊ቺⰎ# ₯㗦Ṇ⪾❺⯞# ╷╊㧲ᜮ# ᄝ⯖ᳶ# ㈮㊻㧲⪚# ^59`1#
# #
# I
Ilj1#71#Jurzwk#fxuyhv#ri#K1#s|orul#lq#Euxfhood#eurwk#frqwdlqlqj#4(#dqg#8(#fhoo#iuhh#
vxshuqdwdqw+sK#dgmxvwhg#wr#715,#ri#ODE1# 侗+3(,/# 侐+4(,/# 侑+8(,# # Gdwd#duh#h{suhvvhg#dv#phdq# 佳# vwdqgdug#ghyldwlrq11#
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. paracasei CH88
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. plantarumPH3A
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. fermentumPH3B
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. fermentum22
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. rhamnosus14
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. sakei KOK
# I
Ilj1#71#Jurzwk#fxuyhv#ri#K1#s|orul#lq#Euxfhood#eurwk#frqwdlqlqj#4(#dqg#8(#fhoo#iuhh#
vxshuqdwdqw+sK#dgmxvwhg#wr#715,#ri#ODE1# 侗+3(,/# 侐+4(,/# 侑+8(,#+Frqwlqxhg,#
Gdwd#duh#h{suhvvhg#dv#phdq# 佳# vwdqgdug#ghyldwlrq1#
# #
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. acidophilusKFRI 150
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. rhamnosusKCTC 3237
0 0.1 0.2 0.3 0.4
0 1 2 3
Absorbance (600nm)
Days
Supernatant of L. plantarumKFRI 708
615151# ⮺╊ቺ# ⨫# ╛ᦋ⧻# ㄲṆ⩪# Ḓ# ⬮☦∞㨎㭂☦# 㫶○# ⅚㫮# #
K1# s|orul ႚ# Ⴏ㧶# ╊○⯲# ⮞⩪▶# ▶❷㧺# ⚲# Ⱒᜮ# 㨏➆ⲛⰒ# Ⰾ⮺ᜮ# ⬮☦∞㨎㭂☦#
╷○Ⰾ# ᮊ⩎ᔲዊ# ᧦ῒⰎ1# ⶖᳶ# ႞⩪▶# ╷○ᢲᜮ# ⬮☦ᜮ# 㪢ᷲḖ# ᰖ# ⚶㫲㧲Ἂ#
⮞ⰿ╛㧖◒㢆# ⧞ᰲ# ὂ◒㪢ᆚ⯞# 㙏㧲⪆# ⮞ⰿ⯖ᳶ# 㫯╊ᢶ1#K1# s|orul ᜮ# Ṿ⭊# ႯᲿ㧶#
⬮☦# ∞㨎⯞# ႚ⹚ᅺ# Ⱒᜮ᠊/# ⬮☦∞㨎㭂☦ᜮ# ⬮☦Ḗ# ⧮ὂᝢ⧞ᳶ# ∞㨎㧲⪆# ⮞⧻⯲#
Ⴏ╊⯞# ⶫ㫮㧶1# ᰖ▶# ⬮☦∞㨎㭂☦⯲# 㫶○# Ⲛ㨎ᜮ# K1# s|orul ⯲# Ⲷቺ⩪# Ⱒ⩎▶#
㨏➆ⲛⰒ# ⲫኖ# ℯⰎ# ^46`1# ❾㩲# ᅊᆖ# sK# 5 ⯲# Ⱂ╊⫞㉃⭃⧻⩪▶# ⬮☦⯲# ᘧᡞ⩪#
ᰖ#K1# s|orul ⯲# ╷ⴎ⯂Ⰾ# ᘬ⧞⯞# 㫯Ⱂ㧲⪚+Gdwd# qrw# vkrzq,1#K1# s|orul ⩪# sK#
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