Supplementary Table. Cases of intracranial aneurysm in Behcet’s disease patients previously reported in the English literature through the PubMed search
Se x
Ag e
Eve nt No.
Location of aneurysms
Multiple aneurys
ms
Aneurys mal rupture
Extra- cranial aneurys
ms
Interventio n
Medical
treatment Outcome
Referen ce
M 12 1 ACom* (-) (+) (-) Clipping Glucocorticoid Recovered (S1)
2
Lt. MCA†
trifurcation (-) (+) (-) Clipping Glucocorticoid Recovered (S1)
3 Lt. PCom‡, Lt.
AChorA§, ACom
(+) (-) (-) - - Died (S1)
F 39 4
Rt. MCA, Lt. MCA, Rt. ACA¶
(+) (-) (-) - Glucocorticoid,
Nitrogen mustard
Recovered (S2)
M 28 5 ACom (-) (+) (-) Clipping - Recovered (S3)
M 57 6 Rt. peripheral MCA (-) (+) (+) Clipping - Recovered (10)
7 Lt. peripheral MCA (-) (-) (-) - Glucocorticoid Recovered (10)
M 38 8 Rt. SCA** (-) (+) (+) Endovascul
ar embolizatio
- Recovered (S4)
n
M 55 9 Rt. vertebral a. (-) (+) (-) Endovascul
ar embolizatio
n
- Recovered (S4)
M 42 10 Rt. AChorA, MCA bifurcation
(+) (+) (-) Clipping - Recovered (S5)
M 37 11 Rt. MCA bifurcation (-) (+) (-) Clipping Recovered (S6)
F 43 12 Rt. SCA (-) (+) (-) Aneurysma
l Excision
- Recovered (S7)
M 38 13 ACom (-) (+) (-) Clipping - Recovered (S8)
F 36 14 ICA†† (-) (+) (-) Endovascul
ar embolizatio
n
Glucocorticoid Recovered (S9)
F 19 15 Multiple MCA (+) (+) (-) Resection
and reconstruct
ion
Glucocorticoid Recovered (S10)
M 38 16 Basillar a. (-) (+) (-) - - Died (S11)
M 36 17 ICA (-) (-) (+) Endovascul Glucocorticoid Recovered (S12)
embolizatio n
M 45 18 PCA§§ (-) (+) (-) - - Spontaneou
sly thrombosed
(S13)
M 34 19 MCA (-) (-) (+) Endovascul
ar embolizatio
n
Glucocorticoid, Cyclophosphami
de, IFN-α
Recovered (S14)
M 44 20 Multiple cerebral arteries
(+) (-) (-)
Glucocorticoid, Azathioprine
No change of aneurysms
(S15)
F 48 21 ACom (-) (+) (+) Clipping Recovered (S16)
M 26 22 PCA, Multiple MCA (+) (+) (-) Endovascul
ar embolizatio
n
Glucocorticoid, azathioprine,
colchicine
Recovered (S17)
*, anterior communicating artery; †, middle cerebral artery; ‡, posterior communicating artery; §, anterior choroidal artery; ¶, anterior cerebral artery; **, superior cerebellar artery; ††, internal carotid artery; ‡‡, superior mesenteric artery; §§, posterior cerebral artery; ¶¶, left anterior descending artery.
Supplementary References
S1. Kerr JS, Roach ES, Sinal SH, McWhorter JM. Intracranial arterial aneurysms complicating Behçet's disease. J Child Neurol 1989;4:147-9.
S2. Zellenski JD, Capraro JA, Holden D, Calabrese LH. Central nervous system vasculitis in Behçet's syndrome: angiographic improvement after therapy with cytotoxic agents. Arthritis Rheum 1989;32:217-220.
S3. Ildan F, Göçer AI, Bağdatoğlu H, Tuna M, Karadayi A. Intracranial arterial aneurysm complicating Behçet's disease. Neurosurg Rev 1996;19:53-6.
S4. Kizilkilic O, Albayram S, Adaletli I, Ak H, Islak C, Kocer N. Endovascular treatment of Behçet's disease-associated intracranial aneurysms: report of two cases and review of the literature. Neuroradiology 2003;45:328-34.
S5. Senel A, Cokluk C, Gündüz C, Yildiz A, Celik F. Cerebral aneurysms in Behçet's disease: a case report. Minim Invasive Neurosurg 2003;46:361-2.
S6. Koçak A, Cayli SR, Ateş O, Saraç K. Middle cerebral artery aneurysm associated with Behçet's disease--case report. Neurol Med Chir (Tokyo) 2004;44:368-71.
S7. Ho CL, Deruytter MJ. Manifestations of Neuro-Behçet's disease: Report of two cases and review of the literature. Clin Neurol Neurosurg 2005;107:310-4.
S8. Zsigmond P, Bobinski L, Boström S. Behçet's disease, associated with subarachnoidal heamorrhage due to intracranial aneurysm. Acta Neurochir (Wien) 2005;147:569-71.
S9. Agrawal S, Jagadeesh R, Aggarwal A, Phadke RV, Misra R. Aneurysm of the internal carotid artery in a female patient of Behcet's
S10. Kaku Y, Hamada JI, Kuroda JI, Kai Y, Morioka M, Kuratsu JI. Multiple peripheral middle cerebral artery aneurysms associated with Behcet's disease. Acta Neurochir (Wien) 2007;149:823-7.
S11. Aktas EG, Kaplan M, Ozveren MF. Basilar artery aneurysm associated with Behçet's Disease: a case report. Turk Neurosurg 2008;18:35-8.
S12. Ozveren MF, Matsumoto Y, Kondo R, Takahashi A. Coil embolization of an unruptured intracranial aneurysm associated with Behcet's disease: case report. Neurol Med Chir (Tokyo) 2009;49:471-3.
S13. Senel K, Pasa O, Baykal T, Ugur M, Levent A, Melikoglu M, et al. Behçet's disease associated with subarachnoid hemorrhage due to intracranial aneurysm. Acta Reumatol Port 2010;35:391-2.
S14. Okutucu S, Karakulak UN, Kalyoncu U, Aytemir K. Cerebral and coronary artery aneurysms in a patient with Behçet'sdisease. Anadolu Kardiyol Derg 2011;11:E31-4.
S15. Younes S, Cherif Y, Mokni N, Berriche O, Zantour B, Boughammoura A, et al. Cerebral Aneurysms: A Rare Feature of Behçet's Disease- A Case Report and Review of the Literature. Case Rep Neurol Med 2013;2013:812158.
S16. Ogata A, Kawashima M, Matsushima T. Behçet's disease with ruptured anterior communicating artery aneurysm following ruptured thoracic aortic aneurysm. Neurol Med Chir (Tokyo) 2013;53:189-91.
S17. Kurdi M, Baeesa S, Bin-Mahfoodh M, Kurdi K. Onyx Embolization of Ruptured Intracranial Aneurysm Associated with Behçet's Disease.
Vasc Med 2013;2013:797045.