This manuscript deals with a comprehensive analysis of the main activities in the provision of additional education at Semey State Medical University. For each semi-solid dosage form liquid limit was determined, the square of the hysteretic loops defined.
Furthermore, the stability of the gel and the absorption of drugs depend on pH level, which also affects the gel's activity against living tissues. The examined samples of the gel showed no visible particles, no debris and no signs of physical instability (phase separation).
Исходно, после восстановления синусового ритма и через 12 мес наблюдения всем пациентам выполняли холтеровское мониторирование электрокардиограммы на аппарате ДК-01 (СЭМ, Россия) [5]. Так, во второй группе достижение целевого уровня АД и его поддержание в течение 12 мес составило 81,2% (у 26 больных).
Results and discussion. During Holter ECG monitoring after 12 months of taking antihypertensive drugs, new cases of paroxysmal atrial fibrillation were recorded in 3 (9.3%) patients of the group treated with bisoprolol. Such a symptom as urinary incontinence often occurs in elderly women, which causes psychological discomfort and reduces the quality of life. Despite the fact that there is a large contingent of women with this symptom in Kazakhstan, most of them do not receive adequate care. positive results of clinical studies allow the drug to be included.
Зерттеу тобындағы 17 науқас келесі схема бойынша полихимиотерапияны (ПКТ) алды: цисплатин 100 мг/м² тәулігіне 1 рет көктамыр ішіне + темозоломид 150 мг/м² тәулігіне 1 рет 1-ден 5-ке дейін. Соңғы топтағы 15 науқас РСТ қабылдады. келесі схема бойынша: цисплатин 100 мг/м² көктамыр ішіне тәулігіне 1 рет + винбластин 6 мг/м² көктамыр ішіне 1-8 күн бойы, дакарбазин 800 мг/м² көктамыр ішіне күніне бір рет.
Vulvovaginal candidiasis is one of the most common diseases that obstetricians and gynecologists have to deal with in practice. And vulvovaginal candidiasis is one of the most common reasons women seek medical attention. More often it affects women of reproductive age, as vulvovaginal candidiasis (VVC) is an essential social problem. And all researchers agree that the correction of the conditions that lead to the development of the disease should be carried out together with antifungal therapy.
Currently, the strengthening of the role of non-albicans species of Candida may be an urgent problem, which requires new approaches in the diagnosis and treatment of the disease. In this regard, the drug "Livarol". Considering the appearance of Livarol on the market of Kazakhstan and its availability for use in gynecological practice in metropolises and regions, the author of the article will analyze clinical and clinical-laboratory data, the results of which will be presented in subsequent publications.
При анализе сопутствующей терапии на визите 1 44 пациента получали один сопутствующий препарат, 29 пациентов получали два и 13 пациентов получали три сопутствующих препарата.
При анализе динамики психического статуса по шкале BPRS (табл. 4) на фоне терапии Солиан® установлено, что снижение суммарного балла до конца наблюдения составило в среднем 36,36%. Как показывают результаты, представленные в табл. 5, в 79 случаях (53,4 %) падение суммарного балла по шкале BPRS не превышало 35 %, в 60 случаях (40,5 %) оно составляло более 35 % от исходного уровня.
Ос
2008) [24] не описывает случаев увеличения массы тела при приеме амисульприда. 1997), в период от начала исследования до окончания исследования потребность в назначении антихолинергических препаратов для купирования симптомов паркинсонизма среди пациентов, получавших амисульприд, снизилась с 41 до 32%, в то время как в группе, получавших галоперидол, этот показатель увеличивается с 39 до 77 %, при этом различия в этих двух группах оказались достоверными (p<.
During the entire period of the study, the patient was observed at least 3 times: at the beginning of taking Solian® (1st visit), after 2 months of treatment (2nd visit) and after 6 months of treatment (3rd visit). Efficacy was evaluated in 148 patients with the following series of scales: "Dynamics of Mental State Scale", PSP, BPRS and SANS. The duration of treatment in the studied group of patients was 6 months, the total duration of observation was 11 months.
When analyzing the dynamics of psychological status using the BPRS, it was found that the reduction of the composite score by the end of the observation was on average 36.36%. By analyzing the dynamics of the variables according to SANS, it was established that the reduction of the composite result by the end of the observation amounted to 35.46%.
Установление диагностического порога или точки отсечки для оценки количественных результатов исследования возможно двумя способами - путем расчета 95% доверительного интервала (ДИ) для полученных данных или с помощью кривой рабочей характеристики приемника (ROC) для построения [ 8]. Затем мы построили кривую ROC для комбинаций интервалов FECO2 (до и Vde/w (2 мл/кг, 2,5 мл/кг, 3 мл/кг), чтобы выбрать наилучшую точку отсечки для нормальных и патологических параметров капнометрии с точки зрения диагностики легочной гиперинфляция (рис. 1) Площадь под ROC-кривой (AUC - площадь под ROC Таблица 2 - Результаты плетизмографии тела и капнометрии у исследуемых больных. Статистически значимая разница между показателями контрольной группы и кривой больных ХОБЛ) отражает качество диагностический тест, при значениях 0,9–1,0 соответствующий отличному качеству, хорошему среднему неудовлетворительному качеству [33].
14 Daily physical activity in patients with chronic obstructive pulmonary disease is mainly associated with dynamic hyperinflation / F. 16 Dynamic hyperinflation during daily activities: means COPD Global Initiative for Chronic Obstructive Lung Disease stage.
QUANTITATIVE AND FUNCTIONAL PARAMETERS OF THE MAIN SUBPOPULATIONS OF LYMPHOCYTES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. According to the severity of the disease, the patients were divided into 3 groups: group I – mild degree (13 patients), group II – moderate degree (19 patients), group III – severe degree (16 patients). The control group included apparently healthy people (15 donors). The determination of T-lymphocyte numbers was carried out in the E-rosette test of lymphocytes with erythrocytes from the guinea pig by the method according to M.
Results and discussion: Quantitative parameters of the main subpopulations of lymphocytes in the peripheral blood of patients with chronic obstructive pulmonary disease were studied using available methods for the assessment of immune status. Patients with chronic obstructive pulmonary disease had significant deviations of immunological parameters from the norm, the degree of which was directly related to the severity of the disease. Key words: immunodeficiency, immune disorders, quantitative parameters of the main subpopulations of lymphocytes in the peripheral blood of patients with chronic obstructive pulmonary disease.
Endocrinology of the menstrual cycle: the interaction between folliculogenesis and neuroendocrine mechanisms // Fertil. Material and methods: A comprehensive clinical and laboratory study of 163 patients with various menstrual disorders aged 19 – 35 years (mean age) was carried out. Results and discussion: It was found that the leading clinical-pathogenic form of menstrual disorders in women of reproductive age under the conditions of iodine deficiency was the central one, which accounts for 58.9% and characterized by hypothalamic-pituitary dysfunction and hypothalamic-pituitary- insufficiency.
The second place in the structure of clinically pathogenic forms of MD was occupied by the ovarian form at 25.8%. The staged differentiated pathogenetic therapy generally led to the recovery of menstrual function - 82.8%, ovulation - 63.8%, and pregnancy - in every second - 41.7%.
Complex pathogenetic therapy was carried out under the control of functional diagnostic tests (FDT) and levels of correctable hormonal parameters. The third place was taken by the thyroid form characterized by subclinical hypothyroidism and with 15.3%.
Incidence, nature, and clinical relevance of mixed cryoglobulinemia in patients with chronic hepatitis C infection, din Exp Immunol 1996;. Introduction: The mixed cryoglobulinemia syndrome is one of the most extrahepatic manifestations of hepatitis C and B. Materials and methods: We studied 16 patients aged from 27 to 59 with symptomatic mixed cryoglobulinemia syndrome diagnosed with hepatitis C and B.
Main part: Mixed cryoglobulinaemia syndrome is more common in patients with hepatitis B+C co-infection than with hepatitis B and C separately. Other systemic manifestations of the syndrome of mixed cryoglobulinemia according to our data appeared with the defeat of: mild - 25%, the kidneys - 31%, the nervous system - 50%, the manifestations of hepatitis - 50%, APS - 13% and with the defeat of the cardiovascular system in the form of non-rheumatic myocarditis with dilated syndrome and abdominal syndrome in one patient.
Эндокринология
HNF1α также экспрессируется в почках, поэтому у пациентов с MODY3, как правило, наблюдается нарушение реабсорбции глюкозы, фосфатов и аминокислот наряду с нарушением функции бета-клеток. Кроме того, было показано, что жесткий гликемический контроль во время беременности снижает возраст, в котором у потомства возникает MODY, более чем на 10 лет [18].
Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxylester lipase gene maturity-onset diabetes of the young (CEL-MODY): a protein misfolding disease //J Biol Chem. Administration of sulfonylureas can increase glucose-induced insulin secretion for decades in patients with maturity-onset diabetes of the young // Diabetes Care. Clinical features and treatment of maturity-onset diabetes in young people // Diabet Metab Syndr Obes.
The expanded clinical spectrum of hepatocyte nuclear factor 1b–maturity-onset diabetes of the young // J Clin Endocrinol Metab. Clinical features and diagnostic criteria of maturity-onset diabetes of the young (MODY) due to molecular anomalies of the HNF1A gene // J Clin Endocrinol Metab.
Стоматология
Most importantly, we can tailor treatment regimens to the specific MODY subtype, for example, patients with mutations in HNF4A (MODY1), HNF1A (MODY3), IPF1 (MODY4) are usually responsive to sulfonylurea therapy and insulin therapy can be discontinued. On the other hand, patients with mutations in GCK (MODY2) can be managed with diet and exercise alone. This makes molecular genetic diagnosis an important part of the treatment of patients with MODY diabetes.
The consequences of complex dental caries are common main reasons for the early loss of temporary teeth. The purpose of the present research was to study the problem of early loss of temporary teeth and their possible consequences. Early removal of temporary teeth leads to incorrect development and deformation of the jaw, as well as to the pathology of the child's bite.
However, there are average expressions of a resorption of roots of temporary teeth, of an eruption of permanent teeth, to which organ-preserving methods of treatment of caries of teeth and its complications must be approached the most. In front of dentists working with children, the need to accurately designate indications for the preservation of temporary teeth and bring them to the physiological change matured.
Гв
Балалар стоматологиялық емханасында 1 жыл бойына 10 айдан 2,5 жасқа дейінгі 12 бала қаралды.
Современные исследования показывают, что снижение массы тела у тучных людей хотя бы на 9 кг уже приводит к снижению всех причин смерти на 25%, смертности от рака на 40-50% и от диабета на 30-40%. Существует корреляция между окружностью талии и риском метаболических осложнений: с повышенным риском у мужчин окружность талии ≥94 см, у женщин ≥80 см, высокий риск у мужчин ≥102 см, у женщин ≥88 см (рекомендации ВОЗ). Влияние микро- и мезоуровня на ожирение в странах бывшего Советского Союза: многоуровневый анализ//.
14 Zhu S., Wang Z., Heshka S., Heo M., Faith M.S., Heymsfield S.B: Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds // Am. In this lecture material, some pathophysiological concepts of overweight and obesity due to genetic, demographic, socio-economic, psychological, neurohormonal and behavioral factors, the study of which is necessary to develop a methodological approach to address obesity prevention, healthy lifestyle and choice of optimal rehabilitation.
Роль различных бактериальных инфекций в возникновении орхоэпидидимита (экспериментальное исследование).
В левом верхнем углу индекс УДК
Сведения об авторе (авторах): инициалы и фамилия автора (прописными буквами); место работы (вуз или организация); город, страна (курсив)
Краткое (информативное) название статьи (прописными буквами)
Аннотация
Текст публикуемой статьи, состоящий из разделов: актуальность, цель исследования, материал и методы, результаты и их обсуждение, выводы
Список литературы
Резюме
Индекс Удк – Универсальная десятичная классификация, присваивается в Научно-технической библиотеке
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