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Uf& : mAP Universiti Malaysia Perlis
INVENTORS
PM DR ZAIlWIIlAMZAH TfNGKU NUR ATIQAH PM DR OTHMAN HASH_
MR HISHAM
CONTACT OETAILS
SCHDOI. DF BIDPRDelSS ENGINEERING, KOMPLEKS PUGAT PENGAJIAN JEJAWI3,
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ARAU: PERLIS.E-lI1Iil: z.iIlHfluJlinap ... my Ttt: Q.4-t7U5N, FIx: 04-117S1876&
ANTIFUNGAL AND ANTIBACTERIAL SKIN PATCH
FROM SELECTED HERBAL EXTRACTS
PROBLEM STATEMENT
Conventional medicated skin patches may have side effects on skin tissues. The patch lacks nutrients important for skin rejuvenation. The used of skin patches enriched with natural herbal extracts can help in the healing process on skin affected by fungal and bacterial infections.
_ PRODUCT DESCRIPTIO~
• This skin patch has an antifungal and antibacterial properties which act against microbes such as Escherichia coli, Staphylococus aureus, Proteus mirabilis and Candida alb/cans.
• It can also inhibit the growth of Vibrio cholera and Proteus vulgaris.
• A new formulation which is a mixture of extracts from Tridax procumbens, Lawsonia inermis and Euphorbia hirta herbs is effective against fungal and bacterial infection on skin.
• The patch is made from cotton gauze enriched with the herbal mixture.
• It is easy to apply, elastic and comfortable for attachment to the skin surface.
Besides, it can also repair the uneven skin structura caused by dry skin, skin rashes and other skin problems.
• These selected herbs contain many active ingredients such as flavonoids, antioxidants, phenols and minerals.
Figure 1: Cotton gauze enriched with active anti- fungal and anti-bacterial properties from herbal extracts.
II COMMERCIAL POTENTIAL
• Herbal extract skin patches, also helps to rejuvenate skin tissues.
• Natural ingredients, non-chemical and non-toxic.
Easy to apply and comfortable.
• Suitable for all ages.
• New medicated formulation using selected herbal extracts
Skin adhesive or patch enriched with active anti-fungal and anti-bacterial ingredients made from natural herbs.
• Novel non-wound skin adhesive or patch for antifungal and antibacterial treatment
II COLLABORATION
• Collaboration with Technology Park Malaysia, Perlis, Malaysia.
Unirnap, 2014 _"""''''''''''~u. for Icorneia 2014
lIIMJlMIM"l!IateConferences on Engineering Mathematic (IPCEM) 2014.
PROCESS ' FLOW
Kac:lng balo ' . "., InIII """ . (TrlchIx procumbon.) (IJ/WlsOn/a /llelml$)
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b) METHODOLOGY
RESULTS
a) RESULT FOR E. COli-INHIBITION THROUGH b) FTIR ANALYSIS - SECONDARY METABOLITES DISK DIFFUSION METHOD
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c) PERCENTA GE 0 F FLAVONOID AND PHENOLIC CONTENT
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0% :'C ..lnili Leaf Ara Tanllh KACING
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ACKNOWLEDGEMENT
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• Authors wish to express their gratitude to MyBrain15 and to those who supported this project.
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U_·~MAP Universiti Malaysia Perlis
INVENTORS
DR IHAHRIIUIi' Aau BAKAR LEE HOI lEOII8 PROF DR UlAli YlAC08 DR WAIt KHAlRUJtIZAIl WAIl! AHMAD DR ZURADZMlN MOHlMAD BAlLAH DR ZUKAIDIIBRAIlII
BOZIIANA.B.
i-PHAD
DR SHAFRlZA tliSIIA MSAH
• DR AFEND! RO"A.
ASIDe PROF DR HlZRY DESA DR SlTI KHAOUAH lAllA PROF DR SHARlfAH Roota DR AHMAD HELMY ABDUL KARIM ASSOC PROf DR MOHAMMAD IQBAL DR ZURAIDA ZAlHUN RUHM.M.S.
AN INNOVATIVE COST-EFFEOIVE HEMODYNAMIC ASSESSMENT TOOL WITH REAL TIME
SITUATIONAL AWARENESS &
CONTACT DETAILS
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u.iftniti llallpia hrli ••
OZIIIIAra., PMlII. Mllapia E· ... iI: IhlIlriRM..e.nirHp.IlII.M\'
CRITICAL LIFESAVING INTELLIGENCE FOR MEDICAL SPECIALISTS
PRODUCT DESCRIPTION
Intelligent Peripheral Hemodynamic Assessment a nd Diagnosis (i-PHAD) is a comprehensive suite of innovative non-invasive hemodynamic monitoring and assessmenttool that provides real-time situational monitoring and critical lifesaving intelligence for vein graft a nd vasculature diseases surveillance related diagnostic applications to both military and civilian medical specialists.
It works by applying a low amplitude high frequency electrical current to the body, measuring the electrical bio-impedance (EBI), which is proposed as biomarker for pathological conditions related to hemodynamic circulation of the extremity.
• Hospitals/Clinics • Universities
• Medical centers • Outpatient departments
• Military • Healthcare companies
• Home healthcare
• Physical attributes of EBI is being profited to propose as pathological biomarker to evaluate hemodynamic circulation of extremities
• Tetrapolar electrode sensor (95% silver 5% chloride)
III TRADITIONAL APPROACHES
_ PROCESS DESCRIPTION
• Preliminary data
• Data acquisition and processing system
• Low cost with performance comparable to high-end Ultrasound - High sensitivity (86.7%) and specificity (93.3%)
• Non-invasive and harmless to the human body - High accuracy (91.6%)
• Easy application in practice with user friendly GUI
• Small and portable COLLABORATION
• Simple procedure and fast response
• Low power usage (battery-powered)
• Convenient to evaluate small segment
UNTVERSm PUTRA MALAYSIA• Suitable for long-term and day-to-day assessment
Hi-li9 liM·iii ", iiiPUBLICATIONS
1. Computational Fluid Dynamic Analysis of the Effect of Kink Conduit in Microvascular Vein Grafting;'lnternational Journal of Mechanical & Mechatronic Engineering 2012; 12(6):53-59.
2. Hemodynamic Study on Upper Extremity: Simulation on Straight Reverse Saphenous Vein Graft, 2012 International Conference on Biomedical Engineering (ICoBE 2012), pp. 207-210.
3. Computational Fluid Dynamic Analysis on Microvascular Vein Grafting: Effect of Mismatched Conduit Diameters, 2012 IEEE EMBS International Conference on Biomedical Engineering, pp.556-561.
4. Theoretical Approach on Vein Graft Survival: Simulation on Vein Graft, International Journal of Medical Engineering and Informatics 2013; 5(4):279-288.
5. Computational Analysis on Upper Extremity Vein Graft: Simulation on Kinked Vein Graft, Procedia Engineering 2012; 41:694-699.
Upper Extremity Vein Graft Monitoring Device After Surgery Procedure: A Preliminary Study, Advanced Materials Research 2014; 925:656-660.
Analysis on Mismatched End-to-End Internal Diameter of RSVG Models, Aus!. J. Basic & App!. Sci. 2014; 8(4):224-229. (BEST PAPER AWARD ICET 2013)
Evaluation of Finger's Hemodynamic For Vein Graft Surveillance Using Electrical Bio-impedance Method. Aust J. Basic & App!. Sci. 2014; 8(4):350-359. (BEST PAPER AWARD .g;~~lm:pedance Cascoded BJTs Current Source for Wideband Electrical Bio-impedance Measurement~t:r::~~o;~~,~~:~edical
