C.V. of Prof. Ashraf Abdel-Naim
NAME
Ashraf B. Abdel-Naim
POSITION TITLE
Professor of Pharmacology and Toxicology,
Faculty of Pharmacy, and King Abdulaziz University, Jeddah, Saudi Arabia
EDUCATION TRAINING INSTITUTION AND LOCATION
DEGREE
(if applicable) YEAR(s) FIELD OF STUDY
Al-Azhar Universiy/University of Texas Medical Branch, Galveston, Texas, USA
Al-Azhar University, Cairo, Egypt, Cairo University, Egypt
PhD
MSc BSc
1995
1990 1984
Pharmacology
Pharmacology Pharmaceutical Sciences
A. Professional Experience:
2005-present Professor of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, KSA.
2001-2005 Acting Head and Associate Professor of Pharmacology and Toxicology, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University.
2000-2001 Lecturer of Pharmacology and Toxicology, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University.
1988-1991 Demonstrator of Pharmacology, Faculty of Medicine, Suez Canal University.
B. Conference & Symposium attended
1994 33rd Annual Meeting of the Society of Toxicology, Texas, USA.
1995 AL-Azhar First International Conference on Recent Advances in Pharmaceutical Technology and Biological Sciences, Cairo, Egypt.
1996 35th European Congress of Toxicology, Alicante, Spain.
1997 The 43rd Scientific Meeting of the Egyptian Society of Clinical Chemistry, Cairo, Egypt.
2002 The 6th Scientific Congress of the Association of Colleges of Pharmacy in the Arab World, Ajman, United Arab Emirates.
Aug 2003 The 7th Delta Annual Symposium on Hepatology, Gastrointestinal Tract and Fever, Tanta.
2004 The 29th International Conference of the Pharmaceutical Sciences and the 8th Scientific Congress of the Association of Colleges of Pharmacy in the Arab World, Cairo, Egypt.
2007 Quality improvement at the institutional level, King Abdulaziz University, Jeddah, KSA.
C. Publications:
1. Potential testicular toxicity of sodium nitrate in adult rats. Aly HA, Mansour AM, Abo-Salem OM, Abd-Ellah HF, Abdel-Naim AB. Food Chem Toxicol. 48(2):572-578 (2010).
2. Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats. Elberry AA, Abdel- Naim AB, Abdel-Sattar EA, Nagy AA, Mosli HA, Mohamadin AM, Ashour OM. Food Chem Toxicol. (2010) [Epub ahead of print].
3. Lactoperoxidase catalyzes in vitro activation of acrylonitrile to cyanide. Nasralla SN, Ghoneim AI, Khalifa AE, Gad MZ, Abdel-Naim AB. Toxicol Lett. 191(2-3):347-352 (2009).
4. Rubus sanctus protects against carbon tetrachloride-induced toxicity in rat isolated hepatocytes: isolation and characterization of its galloylated flavonoids. Badr AM, El-Demerdash E, Khalifa AE, Ghoneim AI, Ayoub NA, Abdel- Naim AB. J Pharm Pharmacol. 61(11):1511-1520. (2009).
5. Chloroacetonitrile induces oxidative stress and apoptosis in mouse fetal liver. Abdel-Naim AB, Nagy AA, Mohamadin AM, El-Mazar HM, Ahmed AE. Toxicol Lett. 190(2):123-127 (2009).
6. Cytotoxic effects of 2-methoxyestradiol in the hepatocellular carcinoma cell line HepG2. El Naga RN, El-Demerdash E, Youssef SS, Abdel-Naim AB, El-Merzabani M. Pharmacology. 27: 84(1): 9-16 (2009).
7. Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits. Afouna MI, Khedr A, Abdel-Naim AB, Al-Marzoqi A. J Pharm Sci. Pharm Sci. 99(1):119-1 27 (2010).
8. Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats. Albukhari AA, Gashlan HM, El- Beshbishy HA, Nagy AA, Abdel-Naim AB. Food Chem Toxicol. 47(7): 1689-1695 (2009).
9. Aroclor 1254 impairs spermatogenesis and induces oxidative stress in rat testicular mitochondria. Aly HA, Domènech O, Abdel-Naim AB. Food Chem Toxicol. 47(8):1733-1738 (2009).
10. Melatonin protects against hydrogen peroxide-induced gastric injury in rats. Mohamadin AM, Ashour OM, El-Sherbeny NA, Alahdal AM, Morsy GM, Abdel-Naim AB. Clin Exp Pharmacol Physiol. 36: 367–372 (2009).
11. 2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft.Azab SS, Salama SA, Hassan MH, Khalifa AE, El-Demerdash E, Fouad H, Al-Hendy A, Abdel-Naim AB. Cancer Chemother Pharmacol 62(5): 893- 902 (2009).
12. Chloroacetonitrile induces intrauterine growth restriction and musculoskeletal toxicity in fetal mouse. Ahmed AE, El- Mazar HM, Nagy AA, Abdel-Naim AB. Toxicol Ind Health 24(8):511-518 (2008).
13. Dibromoacetonitrile-induced protein oxidation and inhibition of proteasomal activity in rat glioma cells. Ahmed AE, Jacob S, Nagy AA, Abdel-Naim AB. Toxicol Lett 179(1):29-33 (2008).
14. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A. Breast Cancer Res Treat 113(1): 9- 19 (2008).
15. High-performance liquid chromatographic method for determination of phenytoin in rabbits receiving sildenafil. Khedr A, Moustafa M, Abdel-Naim AB, Alahdal A, Mosli H. Analytical Chemistry Insights 3: 61- 67 (2008).
16. Toxicity and oxidative stress of acrylonitrile in rat primary glial cells: preventive effects of N-acetylcysteine. Esmat A, El-Demerdash E, El-Mesallamy H, Abdel-Naim AB. Toxicol Lett 171(3):111-118 (2007).
17. Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype. Tadros MG, Khalifa AE, Abdel-Naim AB, Arafa HM. Pharmacol Biochem Behav. 82(3):574-582 (2005).
18. Anti-inflammatory effects of jojoba liquid wax in experimental models. HabashyRR, Abdel-Naim AB, Khalifa AE, Al- Azizi MM. Pharmacol Res 51(2):95-105 (2005).
19. Acrylonitrile-induced toxicity and oxidative stress in isolated rat colonocytes. Mohamadin AM, El-Demerdash E, El- Beshbishy HA, Abdel-Naim AB. Environ Toxicol Pharmacol 19(2): 371-377 (2005).
20. Myeloperoxidase-catalyzed oxidation of chloroacetonitrile to cyanide. Abdel-Naim AB, Mohamadin AM. Toxicol Lett 146(3): 249-257 (2004).
21. In vitro activation of dibromoacetonitrile to cyanide: role of xanthine oxidase. Mohamadin AM, Abdel-Naim AB. Arch Toxicol 77(2): 86-93 (2003).
22. Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers. Salama SA, Au WW, Hunter GC, Sheahan RG, Badary OA, Abdel-Naim AB, Hamada FMA. Environ Mol Mutagen 40: 153 –160 (2002).
23. Potential protective effect of melatonin against dibromoacetonitrile-induced oxidative stress in mouse stomach. Abdel- Wahab MH, Arafa HMM, El-Mahdy MA, Abdel-Naim AB. Pharmacol Res 46(3): 287-293. (2002).
24. Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain. Ghoneim AI, Abdel-Naim AB, Khalifa AE, El-Denshary ES. Pharmacol Res 46(3): 273-279 (2002).
25. Pharmacokinetic disposition of meloxicam in male rabbit plasma. Arafa HMM, Mansour AM, Abdel-Naim AB. Egypt J Biomed Sci 9:289-299 (2002).
26. Bromobenzene-induced cytotoxicity and oxidative stress in isolated rat hepatocytes. MohamadinAM, Ali SS, El-Tawil OS, Abdel-Naim AB. J Egypt Soc Toxicol 27: 23-29 (2002).
27. Differential alteration of cisplatin cytotoxicity and myelotoxicity by the paclitaxel vehicle cremophor EL. Badary OA, Abdel-Naim AB, Khalifa AE, Hamada FMA. Arch Pharmacol 361: 339-344 (2000).
28. The influence of thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats. Badary OA, Abdel-Naim AB, Abdel-Wahab MH, Hamada FMA. Toxicology 143: 219-226 (2000).
29. Role of xanthine oxidase in gastric damadge induced by chloroacetonitrile in rats. Abdel-Naim AB, MohamadinAM. J Egypt Soc Toxicol 22:19-25 (2000).
30. Chloroacetonitrile-induced oxidative stress and toxicity in rat gastric epithelial cells. Mohamadin AM, Abdel-Naim AB.
Pharmacol Res 40 (4): 377-383 (1999).
31. Protective effects of vitamin E and probucol against gentamicin-induced nephrotoxicity. Abdel-Naim AB, Abd El- Wahab HM, Attia FF. Pharmocol Res 40(2): 183-187 (1999).
32. Renal bioactivation of acrylonitrile: in vitro studies. Mostafa AM, Abdel-Naim AB, Abo-Salem O, Abdel-Aziz AH, Hamada FMA. Pharmocol Res 40(2): 195-200 (1999).
33. Induction of oxidative stress in mouse stomach by dibromoacetonitrile. Abdel-Naim AB, Gamal El-Din, AM, Badary OA. J Egypt Soc Toxicol 21: 85-90 (1999).
34. Effects of guar gum and soybean dietary fiber on the control of glucose and lipid metabolism in normal and diabetic rats: A comparative study. Ahmed SH, Abdel-Naim AB. Arab J Biotech 2(2): 219-226 (1999).
35. Toxicity of acrylonitrile on isolated rat hepatocytes: Role of hepatic bioactivation. El-Tawil OS, Abdel-Naim AB. J Egypt Soc Toxicol. 20: 27-32 (1998).
36. Species differences in acrylonitrile disposition: whole body autoradiographic study in rats and mice. Abd Allah AR, Abdel-Naim AB, Hamada FMA, Jacob S, Ahmed EA. J Egypt Soc Toxicol. 19: 43-48 (1997).
37. In Vitro testicular bioactivation of acrylonitrile (VCN). Abdel-Aziz AH, Hamada FMA, Abdel-Naim AB, Ahmed AE.
Pharmocol Res 35(2): 129-134 (1997).
38. Evaluation of acrylonitrile toxicity in the rat. Ahmed AE, Hamada FMA, Abdel-Aziz AH, Abdel-Naim AB. Egypt J Med Sci 14(2): 427-441 (1993)
39. A new therapeutic use of allopurinol: the drug protects the gastric mucosa from the ulcerogenic effect of alcohol.
Hamada FMA, Abdel-Aziz AH, Mostafa AM, El-Ficky MS, Abdel-Naim AB. Arab J Lab Med 18(2): 283-292 (1992).
40. The protective effects of Cucurbita Foetidissima HBK root extract against ethanol-induced gastric ulceration in rats.
Hamada FMA, Abdel-Aziz AH, El-Hamouly MM, El-Ficky MS, Abdel-Naim AB. Egypt J Med Sci 12(2): 573-587 (1991).
