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Research Profile General Information

Name Ibrahim, Saleh

Academic Title Prof. Dr. med.

Institutions University of Lübeck and

University of Sharjah, College of Medicine and Sharjah Institutute for Medical Research E-mail s

[email protected],

[email protected]

Current Position Professor

Research Interests

Genetics of immune-mediated diseases

Gene-environement interactions in complex diseases Mitochondrial role in autoimmunity and ageing

Genetic diversity in Arabs and their influence on disease susceptibility University Education

1981-1987 MBBCh, Universities of Mansoura and Zagazig, Egypt Advanced Academic Qualifications

1993 MD, Department of bacteriology and Immunology, University of Helsinki, Finland Postgraduate Professional Career

Since 2020 Professor, College of Medicine and Sharjah Institute for Medical Research, University of Sharjah, UAE

Since 2017 Professor and Director, Division of Genetics, Institute of Experimental Dermatology, University of Lübeck, Germany

2008-2014 Professor, Genetics of skin Inflammation, Department of Dermatology, University of Lübeck, Germany

2006-2008 Head, Section of Immunogenetics, Faculty of Medicine, University of Rostock, Germany 1997-2005 Group Leader, Institute of Immunology, faculty of Medicine, University of Rostock,

Germany

1996-1997 Research scientist, clinical research group for Multiple Sclerosis, Department of Neurology, Faculty of Medicine, University of Würzburg, Germany

1993-1996 Post-doctoral fellow, Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA

Important Scientific Awards / Functions

2008-2018 Principal investigator, Excellence Cluster Inflammation at Interfaces (EXC 306 1/2) Since 2017 Principal investigator, Center for Research on Inflammation of the skin (CRIS),

University of Lübeck, Germany

2009-2017 Member of the supervisory Board, Central Animal Facility, University of Luebeck, Germany

2009-2017 Animal welfare officer (Tierschutzbeauftragte), University of Luebeck, Germany

Since 2015 Principal investigator, Clinical Research Unit (CRU) Pemphigoid Diseases – Molecular Pathways and their Therapeutic Potential (DFG CRU 303 1/2)

2013- 2022 Founding member, Research Training Group DFG 1743-1/2 Genes, Environment and Inflammation

Since 2015 Member of the Editorial Board of Journal of advanced Research Selected publications (5)

1. Wohlers, I., Künstner, A., Munz, M., Olbrich, M., Fähnrich, A., Ma, C., Hirose, M., El-Mosallamy, S., Salama, M., Busch, H., Ibrahim, S., 2020. A personal and population-based Egyptian genome reference Nat Commun, 11(1), 4719

2. Vorobyev, A., Gupta, Y., Sezin, T., Koga, H., Bartsch, Y.C., Belheouane, M., Künzel, S., Sina, C., Schilf, P., Körber-Ahrens, H., Beltsiou, F., Lara Ernst, A., Khil’chenko, S., Al-Aasam, H., Manz, R.A., Diehl, S., Steinhaus, M., Jascholt, J., Kouki, P., Boehncke, W.-H., Mayadas, T.N., Zillikens, D., Sadik, C.D., Nishi, H., Ehlers, M., Möller, S., Bieber, K., Baines, J.F., Ibrahim, S.M., Ludwig, R.J., 2019.

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Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line. Nat Commun 10, 4097.

3. Bejaoui, Y., Witte, M., Abdelhady, M., Eldarouti, M., Abdallah, N.M.A., Elghzaly, A.A., Tawhid, Z., Gaballah, M.A., Busch, H., Munz, M., Wendorff, M., Ellinghaus, E., Franke, A., Ibrahim, S.M., 2019.

Genome-wide association study of psoriasis in an Egyptian population. Exp. Dermatol. 28, 623–627.

4. Srinivasulu, V., Schilf, P., Ibrahim, S., Khanfar, M.A., Sieburth, S.M., Omar, H., Sebastian, A., AlQawasmeh, R.A., O’Connor, M.J., Al-Tel, T.H., 2018. Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds. Nat Commun 9, 4989.

5. Hirose, M., Schilf, P., Gupta, Y., Wright, M.N., Wright, M.N., Jöhren, O., Wagner, A.E., Sina, C., Ziegler, A., Ristow, M., Ibrahim, S.M., 2016. Lifespan effects of mitochondrial mutations. Nature 540, E13–E14. https://doi.org/10.1038/nature20778

Referensi

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