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Prior ExPosurE to smoking may affECt infants’ rEsPiratory HEaLtH

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1268 Saudi Med J 2017; Vol. 38 (12) www.smj.org.sa

The Cochrane Library. The single most reliable source of evidence in healthcare The Cochrane Reviews highlighted below are available from the Cochrane Database of Systematic Reviews (www.thecochranelibrary.com)

Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback,

and the Cochrane Database of Systematic Reviews should always be consulted for the most recent version of the review.

Prior ExPosurE to smoking may affECt infants’ rEsPiratory HEaLtH

December 6, 2017 - In a Pediatric Pulmonology study of children aged 15 months, increasing hair nicotine levels were related to prior parent-reported smoking exposure and were associated with potential increased risks of wheeze and asthma.

In the study of 376 infants, researchers obtained detailed information from parents about smoking exposure during pregnancy and in the home at 3 and 15 months of age. Data for demographics, wheezing, and asthma were obtained from yearly questionnaires up to age 6 years.

Hair nicotine increased with numbers of smokers and daily cigarettes smoked at home, and was also strongly associated with smoking in pregnancy, according to lead author Dr. Philip Pattemore, of the University of Otago Christchurch, in New Zealand. Although overall the hair nicotine levels in the participants were relatively low, higher levels of hair nicotine were associated with increased risk of wheeze and, though not significant, of asthma at 15 months of age. At older ages the associations were non-significant.

Full citation: Pattemore PK, Silvers KM, Frampton CM, et al. Hair nicotine at 15 months old, tobacco exposure and wheeze or asthma from 15 months to 6 years old. Pediatr Pulmonol. 2017; 1–9. https://doi.org/10.1002/ppul.23903

Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd., reproduced with permission.

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