Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants
reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator
Item Type Article
Authors Abdallah, Abdallah; Weerdenburg, Eveline M.; Guan, Qingtian;
Ummels, Roy; Borggreve, Stephanie; Adroub, Sabir; Malas, Tareq Majed Yasin; Naeem, Raeece; Zhang, Huoming; Otto, Thomas D.;
Bitter, Wilbert; Pain, Arnab
Citation Abdallah AM, Weerdenburg EM, Guan Q, Ummels R, Borggreve S, et al. (2019) Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator. PLOS ONE 14: e0211003. Available:
http://dx.doi.org/10.1371/journal.pone.0211003.
Eprint version Publisher's Version/PDF
DOI 10.1371/journal.pone.0211003
Publisher Public Library of Science (PLoS)
Journal PLOS ONE
Rights This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Download date 19/06/2023 03:03:19
Item License http://creativecommons.org/licenses/by/4.0/
Link to Item http://hdl.handle.net/10754/631047
S4 Fig 32 (7%)
68 (14%)
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88 (18%)
16 (3%) 132 (28%)
24 (5%)
50 (10%)
Virulence, Detoxification, Adaptation Lipid metabolism
Information pathways Cell wall and Cellprocesses PE/PPE
Intermediary metabolism and respiration Regulatory proteins
Conserved hypotheticals