Timing of host feeding drives rhythms in parasite replication
Item Type Working Paper
Authors Prior, Kimberley F;van der Veen, Daan R;O'Donnell, Aidan J;Cumnock, Katherine;Schneider, David;Pain, Arnab;Subudhi, Amit;Ramaprasad, Abhinay;Rund, Samuel SC;Savill, Nicholas J;Reece, Sarah E
Citation Prior KF, van der Veen DR, O’Donnell AJ, Cumnock K, Schneider D, et al. (2017) Timing of host feeding drives rhythms in parasite replication. Available: http://dx.doi.org/10.1101/229674.
Eprint version Pre-print
DOI 10.1101/229674
Publisher Cold Spring Harbor Laboratory
Rights The copyright holder for this preprint is the author/funder. It is made available under a CC-BY-ND 4.0 International license.
Download date 2023-12-27 21:17:35
Item License http://creativecommons.org/licenses/by-nd/4.0/
Link to Item http://hdl.handle.net/10754/627216.1
S2 Fig. Parasite rhythms are inverted in hosts fed in the day versus night. The proportion of parasites at early trophozoite, mid trophozoite and late trophozoite stages (ring stages are presented in Fig 3B) according to the feeding treatment of their hosts (light fed mice, red, and dark fed mice, blue). White and grey bars indicate lights on and lights off, respectively for both groups of mice (lights on ZT 0 and lights off ZT 12). Sampling occurred every 6 hours during days 6-8 post infection with means (± SEM, shaded area, N=10) plotted for each treatment group.
0.00 0.25 0.50 0.75 1.00
12 24/0 12 24/0 12
0.00 0.25 0.50 0.75 1.00
12 24/0 12 24/0 12
0.00 0.05 0.10 0.15 0.20
12 24/0 12 24/0 12 Zeitgeber Time (ZT, h)
Zeitgeber Time (ZT, h) Zeitgeber Time (ZT, h) Early trophozoite proportionMid trophozoite proportion
Late trophozoite proportion
Light fed Dark fed