Yuzuru Otsuka and Nguyen Van Chuyen of AgriculUiral and Food Chemistry.
(2010). Protective and antieataractt ef- 10. Truong Tuyet Mai (2008). On the anti- feets of the aqueous extract ofCleistoea- diabetic effects of Cleistocalyx opercula-
lyx operculatus flower buds on beta-cell tus (Roxb.) Merr and Perry Flower ofStreptozotocin- Diabetic Rats. Joumal Buds. Doctorial Thesis. Tokyo, Japan.
THE REDUCING IN THE POSTPRANDIAL GLYGEMIA OF CLEISTOCALYX OPERCULATUS'S
The study in the reducing in postprandial glycemia of Cleistocalyx operculatus (Roxb.) Merr and Perry flower bud in 20 type 2 diabetic patients was carried out in Hanoi. There are 2 days to do the experiments: the first day, patients were given 150 ml of water with eating the meal (330 kcal);
the second day (after the first day is 7 days), all these 20 patient were given 150 ml of Nu Voi tea and eating the same meal. The blood glucose levels were determined at initial time and at 15, 30, 60 and 120 min after eahng. Results, increase of the postprandial blood glucose level of subjects in the nu voi tea day was significantly lower than that in control day. Significant differences of blood glucose increrments at 30 min was established between the water day and the nu voi tea day (10,67 and 11,92 mmol/L; p<0,05). The difference of blood glucose AUCs between each meal with and without nu voi tea was statishcally significant (23,89 vs. 25,66 mmoVL.hr; p<0,01). The results of study suggested that nu voi can be a potential material supporting to control the post pran- dial blood glucose level in diabetic patients. And, nu voi tea canbe used as a beverage for prevent- ing diabet.
Key words: Cleistocalyx operculatus: type 2 diabetic patient, postprandial blood glucose.
THtTA CAN BEO Pljt vA ROI LOAN I ^ I l ? MAU 6 NGlTdl Ttf 30-59 TUOI TAI THANH PHO HAI DtdNG
Le Due Thuan', Nguyen Thi Lam^, VU Dinh Chinh^.
Nghien ciiu cat ngang tren 1217 doi tugng d thanh pho Hai Duong xae dinh ty le thua can beo phi (TCBP). Nhiing doi tugng cd BMI > 25 tu nguyen tham gia trong nghien ciru se dugc xet nghiem Cholesterol TP, Triglycerid, HDL-C, LDL-C nham xae dinh ty le rdi loan lipid mau (RLLPM) d ngudi thiia can beo phi. Ket qua: Ty le thira can - beo phi la 27,9%, beo phi do I la 1,6%, beo phi dp II la 0,4%. Ty le thira can beo phi d nam la 31,2% cao ban nii la 26,5%. Ty le rdi loan lipid mau d ngudi thira can beo phi la 86,4%; ty le rdi loan lipidmau d nam 87,5% cao hon d nii 85,8%. Ty Ic roi loan cholesterol TP 71% (nam 73,2%; nii 69,8%). Ty le rdi loan triglycerid cao 40,7% (nam 60,7% cao hon so vdi nii 30,2%). Ty le rdi loan HDL-C thip 0,6%. Ty le rli loan LDL-C 2,5%.
Tir khoa: Thira edn beo phi, rdi loan lipid mdu.
' Ths, BS - DH KT thuat Y te Hai Duang 2 PGS, TS - Vien Dinh duang
PGS, TS - DH KT thuat Y te Hai Duong
I. DAT VAN DE
Trong nhii'ng nam gan day cac bang chiing Idioa hge cho thiy cac benh cd lien quan den dinli dudng nhu: thira can - beo phi, tang huyet ap, •vu'a xo ddng mach, dai thao dudng typ II... cd su gia tang d Viet Nam, nhit la khu vuc cac thanh phd ldn [1]. Rdi loan lipid mau (RLLPM) la mdt trong cac van de quan trgng hang diu vl viia xo ddng mach va dang ngay cang gia tang theo nhjp do phat triln ciia xa hdi.
Theo bao cao ciia Td chiic Y t l Thi gidi (WHO), ty le thira can, beo phi tren toan cau da d miic bao ddng. Sd lieu thong ke tii' 84 nude tii nam 1999-2000 da cho thay chi rieng ty le beo phi (BMI
> 30 kg/m^) la 8,7%. 6 My va nhilu nude phat trien khac, TCBP dugc coi la mdt trong nhiing van de siic khoe hang diu trong nhieu nam qua.
Tinh trang rdi loan dinh dudng - lipid dugc cac nha nghien ciiu tren thi gidi d^c biet quan tam, xem day la mot van de quan trgng cua siic khoe cdng ddng d mgi qudc gia tren thi gidi va la bieu hien ma Td chiic Y tl Thi gidi ggi la
"Hdi chii'ng Thi gidi mdi"[2]. Td chii'c Y te thi gidi nhin manh ring mdi quan tam nay khdng chi ddi vdi cac nude phat triln ma cdn ddi vdi cac qudc gia dang d trong thdi ky chuyin tilp vl kinh t l - xa hdi, noi dien ra su thay ddi nhanh chdng v l che do dinh dudng va ldi sdng [2, 3]. C5 ngudi tradng thanh, thira can beo phi thudng de di kem vdi cac rdi loan lipid mau, hdi chiing chuyen boa, lam tang nguy ca mac cac benh man tinh khdng lay nhu dai thao dudng, tim mach, tang huyet ap va mdt sd benh ung thu [2,5].
Cac benh man tinh khdng lay nhiim la ganh nang benh tat, hi' vong d nhilu nude cdng nghiep nhu'ng cQng dang trd thanh
mdi de doa quan trgng ddi vdi cac nuae dang phat trien, nai md hinh benh tat dang thay ddi theo hudng gia tang cac benh man tinh khdng lay nhiem [12]. Rd rang van de thua can beo phi, mot bieu hien de nhan thay ciia tinh trang rdi loan dinh dudng - lipid dang dugc quan tam dac biet tren the gidi va trong khu vuc.
Muc tieu: Xae dinh ty le thira can beo phi va ty le rdi loan lipid mau oi ngudi 30-59 tudi bj thira can beo phi.
II. DOI TU'ONG VA FHlTONG PHAP NGHIEN GtltJ.
1. Doi tu'OTig: Ngudi tradng thanh 30-59 tudi d 8 phudng thanh phd Hai Duong (Thanh Binh, Pham NgG.Lao, Le Thanh Nghj, Quang Trung, Trin Phii, Cim Thugng, Nguyin Trai, Trin Phii) ;, Tieu chuan chon lua: Ngudi tradng thanh 30-59 hidi, khdng bj dj tat bim sinh hoae mac phai nhu gii, veo cot sdng mic cac benh cap tinh, man tinh (nhu lao, dai thao dudng, suy than..) ; phu nir cd thai, cho con bli; va cd su tham gia tu nguyen cua ddi tugng.
2. Phu'cmg phap nghien ciiu:
Thiet ke nghien cmi: Nghien ciiu cit ngang md ta.
C& man vd chpn mau: Nhim xae djnh tinh trang dinh duang, ty le thira can beo phi va cd rdi loan lipid mau ; va mot s6 yeu td lien quan., ap dung cdng thiic:
Z'(l.a/2) P (1 - P) n =
Trong dd: n: Sd ddi tugng cin dilu tra.
p = 0,12; d = 0,05
Z = 1,96 (he sd tin cay tinh theo a = 0,05) vdi khoang tin cay la 95%.
p : Ty le beo phi ude tinh lay theo mdt kit qua nghien cim trade cua Nguyen Cdng Khin nam 2006 la 12%.
Theo tinh toan, mdi nhdm tudi (10 nam /I nhdm tir 30-59) ddi tu'gng nghien ciru se la 163 ngudi. Them 5%o ddi tu'gng du phdng, tdng sd ddi tugng cho mot nhdm tudi la 171 ngudi. Nhu vay tdng sd ddi tugng nghien ciru cho 3 nhdm tudi se la 513 ngudi. Do day la cude dieu tra cat ngang, lay mau chum nen nhan ddi ca mau da tinh toan d tren, ca mau can dugc chgn la: 513 X 2 = 1026 ngudi. Thuc te trong nghien cuu, da dieu tra cat ngang cho 1217 ddi tugng.
Cdc bied'c chon mdu:
Budc 1: Sdng loc: Toan bd 1217 ddi tugng cd trong danh sach kham ciia 8 phudng da dugc can, do chieu cao, vdng eo, vdng mdng, % md co the, huyet ap, sau dd danh gia chi sd BMI theo tudi va gidi so vdi chuan ciia Td chii'c Y te The gidi (WHO,2000).
Bu&c 2: Cac ddi tu'gng cd BMI > 25, ddng y tu' nguyen tham gia nghien ciru se duge cho xet nghiem man xae dinh cac chi sd: Glucose mau. Cholesterol TP, Triglycerids, LDL-C, HDL-C.
Pituongphdp titu titap so lieu:
Can do cac chi so nhan trSc: (WHO, 1981, 1992, 2002) can nang, chilu cao, chi sd BMI,
- Can SECA (do chinh xae 0,01 kg).
Trgng lugng ca the dugc ghi theo kg vdi 1 sd le. Can ddi tugng vao budi sang khi chua an udng gi va da di dai tilu tien. Khi can chi mac quan ao ggn nhat va trir bdt can nang trung binh cua quan ao khi tinh ket qua. Ddi tugng dung ghia ban can,
khdng cir ddng, mat nhin thang, trgng lugng phan bd diu d 2 chan. Can dugc dat d vi tri dn dinh va bang phang.
- Do chieu eao dirng bang thudc gd cd do chia chinh xae tdi milimet. Chieu cao dugc ghi theo cm va 1 sd le. Ddi tugng bd gudc dep, di chan khdng, dung quay lung vao thudc do. Gdt chan, mdng, vai, dau theo 1 dudng thang ap sat vao thu'dc do diing, mat nhin thang . Hai tay bd thdng theo hai ben minh. Keo cai chan dau ciia thudc tii' tren xudng, khi ap sat den dinh dau nhin vao thudc dgc ket qua.
3. Danh gia va phan loai cac chi tieu.
- Danh gia RLLPM theo NCEP ATP III 2001: Cholesterol TP > 5,2 mmol/l, hoae HDL-C < 0,9 mmol/l, hoae LDL-C >3,36 mmol/l, hoae Triglycerid huyet thanh
>2,26 mmol/l.
- Danh gia TTDD: Chi so BMI= Can nang (kg)/Chieu cao-(m):
Dua theo phan loai cua td chii'c WHO (2000) khuyen nghi cho ngudi tra'dng thanh:
BMI
<18,5 18,5-24,99:
25 - 29,99:
30-34,99:
35-39,99
>40
Tinh trang dinh duong Thieu nang lugng truang dien TTDD binh thudng
Tien beo phi- Thira can Beo phi do I
Beo phi do 11.
Beo phi do II
4. Xu ly so lieu: Su' dung phan m l m SPSS 13.0. Sd lieu nhan trac dugc kilm dinh phan bd chuan khi so sanh thdng ke.
III. KETQUA. '
Bang 1. Dac diim dfii tuong theo nhom tuoi va gio-i.
Nhom tu5i Nam Nu' Tong
3 0 - 3 9 4 0 - 4 9 5 0 - 5 9 Cong
n 112
87 173 372
% 30,1 23,4 46,5 100
n 193 281 371 845
% 22,8 33,3 43,9 100
n 305 368 544 1217
% 25,1 30,2 44,7 100
Bang 1 cho thay cd 1217 ddi tugng tai 8 phudng tham gia nghien cii'u cua thanh phd Hai Duong. Ty le cd 30,57% nam va 69,43%o nii'. Nhdm tudi 50 - 59 chiem ty le cao nhat (44 j % ) , tilp dd din nhdm tudi 40 - 49 (30,2%), sau ciing la nhdm tudi 30 - 39 (25,1%).
Bang 2. Tinh trang BMI cua cac doi tu'Ong.
BMI
<18,5 18,5-22,9 23,0-24,9 25,0-29,9 30,0-34,9
>35,0 So sanh 2 gioi
n 23 171
62 109
6 1
Nam
% 6,2 46,0
16,6 29,3 1,6 0,3
n 39 393 189 206 14
4 X2= 8,0
Nir
; p
% 4,6 46,5 22,4 24,4 1,6 0,5
= 0,1
Chung
n % 62 5,1 564 46,3 251 20,6 315 25,9 20 1,6
5 0,4
Trong cae ddi tugng tham gia nghien ciru cd 5,l%o bj thieu nang lugng tradng diin.
Ty le thira can - beo phi chung (phan loai cua WHO-2000) 27,9%; beo phi do I la 1,6%;
beo phi do II la 0,4% . Ty le thira can - beo phi d Nam la 31,2%, Nii: 26,5%.
Bang 3. Tinh trang BMI theo nhom tuoi va gidi.
Tinh trang dinh du'ong (BMI =kg/m2)
Nam
Cong ty le TCBP
Nii
Cpng ty le TCBP
: f.'
<18,5 18,5-22,9 2 3 , 0 - 2 4 , 9 2 5 , 0 - 2 9 , 9 30,0 - 34,9
>35,0 .
< 1 8 , 5 1 8 , 5 - 2 2 , 9 2 3 , 0 - 2 4 , 9 2 5 , 0 - 2 9 , 9 30,0 - 34,9
> 3 5 , 0
3 0 - n 6 62 19 25 0 0 22,3
X2 : 18 114
33 24 2 2 14,5 X^ =
39 tuoi
= 10,J
42,8
% 5,3 55,4 17,0 22,3 0 0
( ; p 9,3 59,1 17,1 12,5 1,0 1,0
; p =
40 - 49 tu6i n 5 40 16 24 2 0 29,9
= 0,2 8 150
58 60 5 0 23,2 0,000
% 5,8 46,0
18,3 27,6 2,3
0
2.8 53,4 20,6 21,4 1,8 0
50- n 12 39 27 60 4
1 37,6
13 129
98 122
7 2 35,3
- 59 ttuoi
% 6,9 39,9 15,6 34,7 2,3 0,6
3.5 34,8 26,4 32,9 1,9 0,5
Ket qua cua bang 3 cho thiy d ca ba nhdm tuoi diu cd ngudi bi thira can - beo phi, dac biet d nhdm tudi 50-59 ca nam va nii diu cd ty le thira can - beo phi rit cao ( 37,6%o va 35,3%)). Tudi cang cao thi ty le thua can beo phi cang cd xu hudng tang cao ca a 2 gidi nam va nii.
Being 4. Tinh trang roi loan lipid mau theo nhom tu6i va gioi o ngu'oi thiia can - beo phi (BMI >25).
Nhom tuoi
3 0 - 3 9 4 0 - 4 9 5 0 - 5 9 Tinh chung
N6n§
Cholesterol TP >5,2 mmol/l
3 0 - 3 9 4 0 - 4 9 5 0 - 5 9 Tinh chung
TG>2,3 mmol/l 3 0 - 3 9
4 0 - 4 9 5 0 - 5 9 Tinh chung
HDL-C< 0,9 mmol/l
3 0 - 3 9 4 0 - 4 9 5 0 - 5 9 Tinh chung
LDL-C> 3,38 mmol/l
n
Nam
± SD (mmol/l) n
; do Cholesterol toan phan theo tuoi, givi 11
10 35 56 41
5,4 ±0,6 5,4 ± 0 , 8 5,7 ± 0 , 8 5,6 ± 0 , 8 5,9 ± 0,5 Nong do Triglycerid theo tuoi,
11 10 35 56 34 11 10 35 56 0
2,2 ± 0 , 9 2,2 ± 0 , 8
2,4 ±1,0 2,3 ± 1 , 0 3,1 ± 0 , 6 2,3 ± 0,4 2,2 ± 0,3 2,4 ± 0 , 5 2,3 ± 0,4
-
Nong do LDL-C theo tuoi, g 11
10 35 56 2
2,1 ± 0 , 3 2,2 ±0,2 2,2 ±0,5 2,2 ± 0,4 3,5 ± 0 , 0
13 35 58 106
74 gioi
13 35 58 106
32 13 35 58 106
1 ioi
13 35 58 106
2
Nir
± SD (mmol/l)
5,5 ± 0 , 8 5,3 ± 0,6 5,8 ± 0,8 5,6± 0,8 6,0 ± 0,6
2,6 ±1,9 1,7 ± 0,8 2,1 ±1,0 2,0 ± 1,2 3,3 ± 1,4
2,1 ± 0 , 2 2,2 ± 0 , 4 2,4 ± 0,5 2,3 ± 0 , 4
0,15
1,9 ±0,5 2,1 ± 0 , 6 2,3 ± 0 , 5 2,2 ± 0 , 5 3,7 ± 0 , 2
P
>0,05
>0,05
>0,05
>0,05 p> 0,05
>0,05
<0,05
>0,05 0,0457
>0,05
>0,05
>0,05
>0,05
>0,05
>0,05
>0,05
>0,05
>0,05
>0,05
Bang 4 cho thiy trang binh cholesterol TP, LDL-C, triglycerid d nam gidi thip ban
nir gidi, tuy nhien su khac nhau khdng cd y nghia thdng ke (p>0,05); Khdng cd su khac
nhau giii'a cac nhdm tudi ve cholesterol trang binh, LDL-C trung binh, HDL-C trang binh
d 2 gidi nam nil', tuy nhien ed su khac nhau trong nhdm tudi 40-49, triglycerid d nam gidi
cao ban so vdi nvi gidi (p<0,05).
Bang 5. Ty le roi loan lipid mau o ngud thira can - beo phi (BMI > 25).
Roi loan lipid mau Nam Nil' Chung
Cholesterol cao Triglycerid cao HDL thap LDL cao
Roi loan lipid mau
n 41 34 0 2 49
% 73,2 60,7 0 3,6 87,5
n 74 32 1 2 91
% 69,8 30,2 0,9 1,9 85,8
n 115
66 1 4 140
"/«
71,0 40,7 0,6 2,5 86,4
Co the nhan thay ty le rdi loan lipid mau trong nliu'ng nguai thira can beo phi (BMI
> 25) chiem ty le rat cao 86,4 %>; d nam la 87,5%, nil' la 85,8%. Ty le rdi loan cho- lesterol mau la cao nhat: 71%), ty le rdi loan triglycerid la 40,7%).
IV. BAN LUAN.
BMI theo phan loai cua WHO, ty le ddi tu'O'ng thira can beo phi chiem ty le klia cao la 27,9%, trong dd ty le thira can beo phi d nam gidi la 31,2%, nii gidi la 26,5%).
Ty le beo phi do I la l,6%o; beo phi do II la 0,4%. Ket qua nghien ciiu nay cao ban so vdi ket qua tdng dieu tra beo phi toan qudc nam 2005 ciia Vien Dinh Duong tren 17213 ddi tugng tudi 25-64 cd ty le thira can beo phi la 16,3%), [6]. So sanh vdi kit qua nghien cuu cua Dinh Van Trang va cdng su nam 2007 tren ddi tugng sT quan Quan chiing Phdng khdng khdng quan thi ty le thua can beo phi cua chiing tdi thip ban (27,9% so vdi 55,8%)[8]. 6 ca nam va nii' tudi cang cao thi cang cd xu hudng bi thira can beo phi tang.
Ty le rdi loan lipid mau d ngudi cd BMI > 25 la 84%, theo nghien ciiu ciia Dinh Van Trung va cdng sir tren ddi tugng la can bd thudc dien quan ly sire khoe cua Ban Bao ve Sire khoe tinh VTnh Long (2003) thi ty le RLLPM la 80,9%, cdn theo Trin Dire Thg va cdng su (2000- 2001) ty le RLLPM tren benh nhan giam dung nap glucose la 84%; cac kit qua nay
ciing tuong ddi phii hgp vdi ket qua nghien cii'u cua chiing tdi [8]. Nghien ciiu cua Nguyen Thj Phugng va cdng su tren benh nhan Gut tai Benh vien Chan thuang chinh hinh thanh phd Hd Chi Minh nam 2006, cho thiy ty le RLLPM thuc su la 84,41%; cdn ty le RLLPM thuc sir cung vdi nguy ca bi rdi loan la 90,90%o, nghien cuu cua chung tdi cho thay, ty le rdi loan thanh phan cholesterol la 71%), phu hgp voi ket qua nghien cuu cua Nguyen Minh Tuan (2008) a nguai tra'ong thanh thua can a Thai Nguyen la 69%) CO tang cholesterol toan phan[9]. So sanh vai ket qua cua Dd Dinh Xuan va Tran Due Long tien hanh nghien ciiu ngang thuc hien d 3 tinh ddng bang Bac Bd, 630 ngudi tren 40 tudi dugc chgn ngau nhien vao nghien ciiu de xet nghiem cac chi sd lipid mau co 41,9% tang cho- lesterol, ty le tang cholesterol cua chung tdi cao han (71%) so vai 41,09%)) nhung day la ty le rdi loan cholesterol tren nguai CO thua can beo phi. Nghien ciiu cua Rafal S. Filip va cdng sir (2006) d -vung Lubin (Ba Lan) thi ty le cholesterol cao hanvdi77,3%[ll].
Ty le triglycerid cao a nguai TCBP la 40,7%, phu hgp vai nghien ciru ciia Le Khac Due va cpng su (2007) khoang 40%, va ciia Nguyin Minh Tuan (2005) tai Thai Nguyen la 32,5%o a nguai thua can; 37%) a nghien cuu ciia Do Dinh Xuan va cdng su. So sanh ty le rdi loan
triglycerid a nguoi TCBP thi ty le trong nghien cuu cua chung tdi thap han so vai nghien cuu cua Dinh Van Trang la 47,9%[7].
Cholesterol toan phan va triglycerid dugc coi la cac chi sd danh gia nguy ca vua xa ddng mach. Neu cac chi sd nay cang cao, nguy ca vua xa ddng mach cang cao. Ben canli do, chi sd HDL-C lai dugc coi la cholesterol "tdt", co lgi vi no van chuyen cholesterol ra khoi td chuc de giam nguy ca vua xa ddng mach. Ket qua ehi CO 0,6%) sd nguoi TCBP trong nghien cuu cua chung tdi co HDL-C thap.
Ty le LDL-C cao la 2,5%o a nguoi thua can beo phi, thap ban so vdi ket qua nghien euu cua Nguyen Minh Tuan (2005) tai Thai Nguyen la 46,5%; thip hon so voi ket qua cua Le Bach Mai va cdng su (2004) la 8,23%.
V. KET LUAN.
1. Thuc trang thua can beo phi fr ngu'di tru'O'ng thanh tuoi 30-59 tai thanh ph6 Hai Du'cng:
- Ty le thira can - beo phi la 27,9%), beo phi do I la 1,6%, beo phi do II la 0,4 %.
- Ty le thua can beo phi d nam la 31,2%) cao ban d nii la 26,5%o.
- Ty le thiia can beo phi cd xu hudng tang len theo tudi. Tudi cang cao, ty le thii'a can beo phi cang cao.
2. Ty le roi loan lipid mau 6" nguoi thiia can - beo phi.
- Ty le rdi loan lipid mau chung d ngudi cd BMI >25 la 86,4 %; d nam la 87,5%,, cao ban d nu.' 85,8%)
- Ty le rdi loan cholesterol toan phan 71%o (nam 73,2%; nii' 69,8%).
- Ty le rdi loan triglycerid cao 40,7%o (nam 60,7% cao ban so vdi nii 30,2%))
- Ty le HDL-C thap 0,6%.
TAI LIEU THAM KHAO
1. Pham Gia Khai, Nguyin Lan Viet, Do Quoc Hiing, Nguyin Bach Yen (2002),
"Nhgn xet ve mdt sd rdi loan dinh dirong vd ehuyen hoa d ngudi tdng huyet dp'', Y hoc thuc hanh 418:11-18.
2. WHO (2003). Che do dn, dinh duang vd dit phdng ctia cdc benh mdn tinh. Dich chuyen tir ban tieng Anh xuat ban cua WHO, Geneva (Vien Dinh duang dich):
5-33,156-163.
3. Hoang Tich HuyIn (2004). Beo phi - benh nhdn cua the ky 21. Tap chi Nghien cuu Y hpc, Dai hpc Y Ha Npi; 28 (2);
111-115.
4. Le Bach Mai, Nguyen Cong Khan vaCS.
(2004). Thuv trgng thira cdn — heo phi d ngudi 30-59 tudi tgi noi thdnh Hd Noi ndm 2003. Tap chi Y hpc thuc hanh, so 496, trang: 48 - 53.
5. Ha Huy Khdi, Nguyen Cong Khan (2002). Tlura cdn va beo phi, mot vdn de sire khoe edng dong moi a nuae ta. Tap chi Y hpc Thuc hanh so 418; 5-9.
6. Nguyen Cdng Khan, Nguyen Dire Minh, Pham Van Hoan, Le Bach Mai (2008).
Lien quan hogt dgng the lice vdi tinh trgng thira cdn, beo phi d ngudi trudng thdnh Viet Nam. Tap chi DD&TP - Tap 4 - sd 2 - Thang 9 nam 2008.
7. Dinh Van Tmng (2008). Thuv trgng thua edn beo phi vd rdi loan lipid mdu d cdn bg qudn ddi don vi X. Tap chi Dinh Dudng va Thuc pham.Tap 4. Sd 3+4, thang 12 nam 2008; 48-53.
8. Le Van Trung, Lu'u Thanli Giu, Trin Van Ut. (2003). Khdo sdt cae dae diem cua rdi logn chuyen hoa lipid, lipoprotein mdu trin ddi tugng cdn bo dien qudn ly sice khde eita Ban B VSK tinh VTnh Long.
9. Nguyin Minh Tuin, Pham Thi Hdng Van. Thuc trgng thua cdn beo phi a ngtroi tnrang thanh tgi Thai Nguyen. Tap chi Dinh Duong & Thuc phim. Tap 2, sd 3+4/2006; 54-59. ' . ,'
10. Robert B. Taylor, Alan K. David, Thomas A Johnson, Jr.D. Melessa Philips, Joseph E. Scherger (2004): Roi logn lipid mdu. Y hoc gia dinh cac nguyen ly va thirc hanh, Nha xuat ban y hoc, 1708- 1720.
11. Rafal S. Filip, Lech Panasiuk, Agnieszka Hazatym-Maj, Radoslaw P. Radzki, Marek Bienko, Iwona Puzio (2006).
Serum lipid profile and metabolic syn- drome occurrence among obese rural women from Lublin region (Estern Poland). Ann Agric Environ Med; 13; 77- 80.
12. WHO, Geneva (2000). Obesity. Prevent- ing and managing the global epidemic - technical Report. Series 894.
Summary
OVERWEIGHT/OBESITY AND BLOOD LIPID DISORDERS IN PEOPLE 30-59 YEARS OLD IN HAI DUONG CITY
A cross -sectional study was conducted in 1217 subjects in Hai Duong city to determine the rate of overweight / obesity and blood lipid disorders among overweight/obesity targets ageds 30-59.
The subjects with BMI > 25 voluntarily participated in the study. Their total cholesterol, triglyc- eride, HDL-C, LDL-C were identified to determine the rate of blood lipid disorders in obese peo- ple. The results showed that: The rate of overweight was 27.9%, obesity was 20.6%, obesity grade I was 25.9%, and obesity grade II was 27.9%. Overweight and obesity in females (26.5%) was lower than in males (31.2%). The rate of lipid disorders in obese people was 84% and that in males (87.5%) was higher than in females (56.2%). The rate of high total cholesterol was 71%
(males 73.2%, females 69.8%). The rate of high triglyceride was 40.7% (males 60.7% higher than females 30.2%), low HDL - C was 0.6%, high LDL-C was 2.5%.
K.&yv/orAs: Overweight, obesity, blood lipid disorders.
TtNH TRi^NG DINH DirdjNTG, KHAU PHAN v A MOT SO YEU TO LIEN QUAN CUA HOC SINH 6-14 TUOI TAI
HUYEN S6C SdN, HA NOI
Ho Thu Mai', Pham Vdn Hoan^, Nguyin Hieu Bdc^
Nghien cuu dugc thuc hien thang 9 nam 2007 tren 2100 hpc sinh tai 4 trudng tilu hpc va trung hpc CO sd huyen Soc San, Ha Npi. Muc deu: Danh gia thuc trang dinh duong cua hpc sinh 6 din 14 tuoi va mpt so yeu to lien quan. Phuang phap: Cat ngang md ta c6 phan tich. Kit qua: Khdng c6 sir khac biet ve can nang tmng binh giira hpc sinh nam va hpc sinh nii. Q tudi 11,12 chilu cao nu cao hon nam (p<0,05) nhung din tudi 14 thi nam lai cao han nii (p<0,05). Ty le thilu dinh duong nhe can chung ciia nhdm 6-8 hidi la 14,9%, d nii cao hon nam, nhung chi din 7-8 tudi mdi cd su khac biet cd y nghia (p<0,01). Ty le thilu dinh dudng thip cdi cua nhdm 6-8 tudi la 28%;
' Ths, Bs - Vien Dinh duong '- PGS, TS - Vien Dinh duang
^ KS - Vien Dinh duong
