VIETNAM MEDICAL JOURNAL N°1 - FEBRUARY - 2018 . HuTa Thanh Thuy va Nguyen Thanh Hu'dng
(2012), "Cac yeu to anh hUdng tdi gia thuoc va tinh phu hdp cua mot so van ban quan ly gia thuoc". Tap chi y hoc thUe hanh, 2012(818-819), tr. 380-385.
. Angelino, A., Khanh, D. T., An Ha, N., &
Pham, T. (2017). Pharmaceutical industry in
growing Vietnam: Sluggish sector
market. International journal of environmental research and public health, i4[9), 976.
. Lieb K. va Scheurich A. (2014), "Contact between doctors and the pharmaceutical industry their perceptions, and ttie effects on prescnbimi habits", PLoS One. 9(10), tr. ellO130.
DAC DIEM LAM SANG, XET NGHIEM CUA BENH NHI BI THIEU MAU THIEU SAT TAI VIEN HUYET HOC -
TRUYEN MAU TRUNG U'aNG NAM 2 0 1 5 - 2 0 1 6
T O M TAT
Cac tac gia tien hanh nghiSn euU dac diem lam sang, xet nghiem ciia b?nh thieu mau thieu sat d benh nhi tai Vien Huyet hpc - Truyen mau Trung Udng trong cac nSm 2015-2016. Mpc tieu. Mo ta mgt so dac diem lam sang, xet nghiem eiia benh nhi bi thieu mau thieu sat. Ddi tu'dng va phddng phap nghien cuir 57 benh nhi, 6iihc chan doan xac dmh la thieu mau thieu sat tJieo tieu' chuan cua WHO 2001. PhUdng phap nghien cUu: mo ta cat ngang, tien cdu. Ket qua nghiin clhr. (1) Cae tn|u chUng lam sang noi bat:
Trieu chirng met mdi d nhom chay mau va nhom phoi hdp chiem 100%, d nhom chUa ro nguyen nhan chi cd 52.4%; 100% benh nhi eo trieu chUng da xanh niem mac nhdt; Tneu chUng nhip tim nhanh gap ty le cao tU 71,4 % trd len. (2) Cac trieu ehiTng can lam sang ndi b?t: MUc do thieu mau la pho bien (Hb: 73,2 ± 14,3); Gap t / le' 93% benh nhi cd mUc MCV nhd hdn 80 fl; c6 100%__tre cd nong dp MCH <28 (pg); cd 96,5% mire dp sat huyet thanh < 7 pmol/l; ed 86% cd lUdng ferritin < 15 ng/ml; lUpng Transferrin tang cao.
Cac kit qua nghien CLTU tren da dUdc ban luan.
WAftoa; Thieu mau, thieu sat, benh nhi.
SUMMARY
CLINICAL AND TEST CHARACTERS OF PEDIATRIC PAnENTS WITH IRON DEFICIENCY ANEMIA AT THE NATIONAL INSTTIXnE OF HEMATOLOGY AND
BLOOD TIUNSFl^SION I N 2015 - 2016 The authors have studied clinical and para-clinieal characters of iron deficiency anemia on pediatric patients at the National Institute of Hematology and Blood Transfusion in 2015 - 2016. Objectives: to describe some clinical and Para-clinical characters of pediatric patients with iron deficiency anemia via W/HO 2001 standards. Research method: prospective cross-sectional study. Results: (1) Prominent clinical
•' Viin Huyet hoc - Truyen mau TW
^Tnfdng Daifigc YHa No' Chju trach nhilm chfnh: Nguyen Trilu Van Email: [email protected] Ngay nhan bai: 19.10.2017 Ngay phan bien khoa hoc: 11.12.2017 Ngay duyet bai: 22.12.2017
Nguyin TriSu V a n \ Nguyen Ha Thanh^
symptoms: found fatigue symptom 100% in bleeding group and blending group, 52.4% in undefined group;
100% of pediatric patients found pale skin ant) mucosa; symptom of fast heart beat found witti high percentage, 71.4% and over. (2) Prominent clinical symptoms: common met anemia (Hb: 73.2 ± 14,3);
93% pediatric patients met with MCV lower than 80 fl;
100% of them with MCH <28 (pg); 96.5% widi serum Fe<7pmol/l; 86% with fernUn < 15ng/ml; Transferrin highly increases. The above results have been discussed.
/feywOTife-anemia, iron deficienc/,pediahic patent L OAT V X N O E
Theo thong ke eiia To chu'c Y te the gi^i, trong nhij'ng nam gan day, ty le thieu mau thieu sat 6 phu nU mang thai la gan 42%, trong doci cac nUdc dang phat trien chiem tdi 56%, d cac nUdc phat trien chi chiem 18%. Tai Viet Nam, theo nghien ciTu ciia vien Dinh dUdng thi co tiT 2 % den 5% nam gidi trudng thanh va phu niJ' man kinh co thieu mau do thieu sat, tir 4% den 13% ngUdi bj benh dUdng rupt bj thieu mau do thieu sat. Tac gia Bhutta va Black cho rang thieu sat da gdp phan gay ra hdn 20.000 ea tir vong moi nam d tre em dUdi 5 tudi. Vi vay, nhom nghien ciTu da tien hanh thue hien de tai "Dac diem lam sang, xet nghiem ciia benh nhi bi thieu mau thieu sat tai Vien Huyet hpc - Truyen mau Trung Udng nam 2015-2016" vdi mue tieu: Moja mpt so dac diem lam sang, xet nghiem cOa benl\
nhi bj thieu miu thieu sat.
n. B 6 I nrpisiG VA PHI/ONG PHAP NGHI§N COU 2 . 1 . Ddi tu'dng nghien cuXi
2.1.1. Tieu chuan Ida chgn bpnh nhan - Doi tUdng nghien culi: gom 57 benh nhi dUdc chan doan xac djnh thieu mau thIeu sat va dieu tri tai Vien Huyet hoc - Truyen mau Trung Udng tir thang 5/2015 den thang 5/2016. ^
- Tieu chuan ehan doan thieu mau thieu sat:
Theo tieu chuan ciia WHO nam 2001; (1) HD
<120g/l; (2) Ferritin huyet thanh < 30ng/ml.
TAP CHl Y HOC VigT MAM TAP 463 • THANG 2 • SO 1 - 201S - Ooi tUdng nghien cull dUdc chia thanh 4
nhom benh theo nguyen nhan nliusau:
+ Nhdm chay mau: ed 13 benh nhi. Nguyen nhan gay chay mau do: loet da day, tri, ung t h u dudng tieu hda, giun mdc.
+ Nhdm khong cung cap dii va kem hap thu sat (KCCO va KHT): co 14 benh nhi. Nguyen nhan do:
che dp an kieng, cat da day, eat doan rupt.
+ Nhom phoi hdp: cd 9 beiih nhi. NhfJYig benh nhi nay bj thieu mau thigu sat do 2 hoae 3 nguy§n nhan gay neu tren.
+ Nhdm ehUa ro nguyen nhan (CRNN): cd 21 benh nhi.
2.1.2. TiSu chuan loai triy
- Nhutig benh nhi hoae bd, me b§nh nhi Widng dong y tham gia nghien eUu.
- Nhutrg benh nhi thieu mau thieu sat cd suy than, benh ly bam sinh hong cau, benh mau ac tfnh.
2.2. Phu'dng phap nghien cu'u 2.2.1. Thiet ke nghiSn cdu: Nghien ciru mdta eat ngang.
2.2.2. Cach chgn mSu: Theo phUdng phap
ehpn mau thuan tien; Trong thdi gian nghien ciTu nhij'ng benh nhi nao dii tieu chuan thi d u ^ vao nhdm nghien eiTu.
III. KET QUA N G H l i N CU'U 3 . 1 . Oac diem nhom nghien cu'u 3.1.1. £>ac diem phan bo tud'i cua nhdm nghiSn cu'u
Ba/jgl:7)^lidptimtn)r^nlmn/ighiemcutt Nhom tuoi
Tre em
< 2 tuoi 2 - 1 1 tuoi 12 - 16 tuoi Tong
n 17 11 29 57
o/o 29,8 19,3 50,9 100
Bang 2: Cac trieu chu'ng cdnang thu'dng gap
Nhan xet: Nhom benii nhi chiem ty le cao nhat la 50,9% d Iffajuoi 12-16.
3.1.2. Dac diem phan bd ve gidi cua nhom nghien cii'u
Trong 57 benh nhi, nam co 33 tre (58%), nii' cd 24 tre (42%). _
3.2. Dac diem lam sang cua benh nhi thieu mau thieu s^t
3.2.1. Cac trieu chii'ng cdnang
Nguyen nhan Trilu chufng
Nhom chay mau ( n = 1 3 )
Nhom KCCe va K H T s a t ( n = 1 4 1
Nhom phoi hop ( n = 9 )
Nhdm _ _ i r v
CRNN 211
Met moi 52,4
Hoa mat chong mat 88,9
Dau dau 38,5 35,7 66,7
An kem 30,8 28,6 77,8
Kem tap trung I 5 I 38,5 I 3 I 21,4 I 5 I 55,6 I 1 IVhan xet: Trieu chutig met moi d nhom chay mau va nhom phoi hop chiem 100%, CRNN chi CO 52.4%. Trieu chu'ng hoa jTiat chong mat gap ty le thap d nhom CRNN (19%).
3.2.2. Cac trieu chu'ng thtrc the
Bang 3: Cac jrigu chutig thuc thS'thWdng gap
81,0
Nguyen nhan | Nhom chay mau J chu'ng
Nhom KCCe va KHT sat
Nhom phoi htfii Da xanh niem mac nhdt
78,6 Nhip tiiTi nhanh
Kho tha 21,1 11,1
Tieng thoi tam thu I 2 I 15,4 I 1 I 7,7 I 0 I 0 I 1 IVh^n xet: Tat ca benh nhi deu co trieu chu'ng da xanh niem mac nhdt. Trieu chijrng tieng thoi
4,8 tam thu d nhom CRNN chi chiem 4,8%.
3.3. ffac diem xet nghiem cua benh nhi trong nghien CO'U 3.3.1. Bac diem dong hong cau
Bang 4. Gia tri trung binh cac chi so hong cau trudng thanh va bonp cau lu'dt Chi so HC
RBC(l/L) Hbla/iJ MCV m MCH (pq) MCHC M) HCL(%) RL)W (%)
Gia tri 3,8 ± 0,4 73,2 ± 14,3 62,4 ± 11,2 18,0 ± 4,2 286,2 ± 23,2 2,2 ± 1,3 20,3 ± 3,3
VIETNAM MEDICAL JOURNAL N°1 • FEBRUARY - 2018
Nhan xet: Cae ehi so ve so lUdng HC, nong do Hb, MCV, MCH, MCHC deu giam so vdi binh thudng. Hong a u lUdi, phan bo kfch thUde hong eau tang eao.
Bang 5. So Iddng HC va nong dp Hb trung binh theo cac nhom Nhom tuoi
Nhom chay mau (1) Nhom KCCD va KHT sat (2)
Nhom phdi hdp (3) Nhom CRNN (4)
P
So lu'dng H C ( T / l ) - \ = t J f O 3,9 ± 0,6 3,8 ± 0,4 3,7 ± 0,5 3,8 ± 0,4 0i.j; Pi.3iPi.4; P2j; P2.4; PV< > O , 0 5
NongdoHbCg/D-^-L-so 77,7 ± 21,2 70,2 ± 15,4 70,0 ± 11,5 73,8 ± 8,5 P i i ; Pr.i; Pi4;Pu;P2.i;Pi.>o.05 Nhan xet: Sd lUdng hong cau va ndng dp hemoglobin khdng cd sU khac biet khi so sanh tijftig cap giu'a cac nhdm tlieo nguyen nhan gay benh.
Bang 6. Gia tri cua thi tich trung binh hdng cau MCV
Nhom benh Nhom CM (1) Nhom KCCB va KHT sat (2)
Nhom phoi hdp (3) Nhom CRNN (4)
Tong P
Nhan xet: Trong^ nhom b^nh _
< 8 0 f l n 12 13 9 19 53
%
92,3 92,9 100 90,5 93,0
P u ; Pi nhi nghien cu\i khong
8 0 - 1 0 0 fl n 1 1 0 2 4
%
7,7 7,1 0 9,5 7,0
•i) P1.4; P2.3; P24; Pr)4 >
> 100 fl n 0 0 0 0 0
%
0 0 0 0 0 0,05cd benh nhi nao co mu'c MCV idn hdn 100 (fl). Ga"p ty lg 93% benh nhi cd mire MCV nhd hdn 80 (fl).
Bang 7. Gia tn cua Iddng huyS'tsac to trung binh hdng cau MCH
Nh6m benh Nhdm CM (1) Nhom KCCD va KHT sat (2)
Nhom PH (3) Nhom CRNN (4)
Tong
< 2 8 p g n 13 14 9 21 57
%
100 100 100 100 100
2 8 - 3 2 pg n 0 0 0 0 0
%
0 0 0 0 0> 3 2 p g n 0 0 0 0 0
%
0 0 0 0 0 Nhan xet: 100% tre co nong do MCH <28 (pg).Bang 8. Gai tti aia nong do huyet sac td trung binh hong cau Nhom benh
< 3 0 0 g / l 3 0 0 - 3 2 0 g / l
%
320-360 g/l Nhom CM (1)
Nhdm KCCD va KHT sat ( 2 ) "
46,2 30,8 23,1
14,3
Nhom PH (3) 11,1
CRNN (4) 4,8
Tong 10,5
Pl2,Pl3,P23,P24 > 0 , 0 5 P34. P l 4 < 0 , 0 5
Pl2,Pl3,P23,P24 > 0 , 0 S P34. P l 4 < 0 , 0 5
Pl2,Pl3,P23,P24,P34
>0.05, Pi4<0,0S Nhan xit: Nhdm benh nhi cd MCHC < 300 (g/i) chiSm ty IS kha cao la 73,7%.
3.3.2. Oac di^m dau an sat huySt thanh Bang 9. Gla tri cua Sat huyet thanh d cac nhom
Fe Nhom benh
Nhdm chay mau (1) Nhdm KCCD va KHT sat (2)
Nhdm phdi hcJD(3) Nhdm CRNN (4)
Tonq
^ Nhpnxet:Tre em thudc nhdn
< 7 iimol/l n 13 12 9 21 55 1chay mau
1 0 0
%
85,7 1 0 0 100 96,5 nhom phc
7 - 2 7 u m o l / l n 0 2 0 0 2 i hdp va nl"
%
0 14,30 0 3,5 6m CRNN c
> 2 7 |jmol/l n 0 0 0 0 0 leu cb 100
%
0 0 0 0 0% mii'c do sat huyet thanh du'di 7 (pmol/l).
Bang 10. Gii tri ciia Ferritin
Nhom benh < 15 n q / m l 15 - 3 0 ngTiiir
Nhom chav mau f l )
TAP CHI Y HOC VIET NAIVI TAP 463 -THANG 2 - s o l -2018 Nhdm KCCD va KHT sat (2)
Nhdm phoi hdp (3) Nhdm CRNN (4)
Tong P
12 7 20 49
85,7 TI,S 95,2 86,0 p, 2>0,05; Pi 3<0,05;
2 2 1 8
14,3 22,2 4,8 14,0 D,4>0,05; D>,>a,05: p,4>0,05; p,.4>0,0i Nh$n xet: Co sij" khac biet giiJa nhdm chay mau vdi nhdm phoi hdp khi so sanh mtfc do ferritin
< 15 ng/ml vdi cac nitfc do khic nhau.
Bang 11. Gia tri cua Transferrin Transferrin Nhom tuoi
Nhdm CM (1) Nhom KCCD va KHT sat (2)
Nhdm PH (3) Nhdm CRNN (4)
Tang P
<200mg/di n 0 0 0 0 0
%
00 0 0 0 Pi,2>0,05; Pi,3>0,05
200-2S0mg/dl n 2 0 0 1 3
15,4
%
0 0 4,8 5,3
; pi.4>0,05; P2.3>0,05
>250mg/dl n 11 14 9 20 54
Vo 84,6 100 100 95,2 94,7 P2,4>0,05; P3,4>0,05 Nhan xet: Khong eo trUdng hdp nao co mUc transferrin < 200mg/dl. Mdc transferrin >300mg/dl chiem t / le rat cao la 94,7%.
IV. BAN LUAN
4 . 1 . Mot sdi dac diem ve tuoi va gidi ciia doi tu'dng nghi§n cii'u: Trong 57 benh nhi, thieu mau thieu sat gap d tat ea eae giai doan phat trien eua tre, trong do nhdm tudi tir 12 den 15 tudi chiem ty le eao nhat la 50.9%, tiep theo la lira tuoi nhd hdn 2 chiem 29,8%, tudi tir 3-11 chiem t / le thap nhat la 19.3%. Ket qua nghien ciiu tUdng tU nghien eiTu cua M. Lan va P.T.L.
HUdng. Theo tac gia Mai Lan thi nhdm benh nhi tren 10 tuoi chiem 5 4 , 1 % , cdn tac gia Lan HUdng thi Mia tuoi ttr 11 - 16 tuoi ty le cao nhat la 43%. Ty le tre nam 58%, nu' 42%. Ket qua nay tUdng tU vdi tac gia M.Lan (nam 62,4%, nD' 37,6%) va t^c gia P.T.L.HUdng, nam 6 2 % .
4.2. Dac diem lam sang cua benh nhi Uiieu mau thieu sat
a nhdm nghien cufu, cae trieu chu'ng cd nang nhU: met mdi, chii'ng hoa mat chdng mat chiem t / le rat cao, cac trieu dau dau, an kem, kem tap truiig CO ty le thap hdn. Ve eae theu chimg thUe the, khi tham kham thi 100% benh nhi cd trieu chiing da xanh, niem mac nhdt. Trieu chii'ng nhip tim nhanh gap ty le kha cao: nhdm chay mau la 76,9%, nhom khong cung cap du va kem hap thu sat la 78,6%, nhom phoi hdp la 88,9%
va nhdm chua ro nguyen nhan la 71,4%. Trieu chutig tarn sang ciia thieu mau thieu sat phu thupc vao mu'c dp nang eiia benh. Neu thieu mau nhe thUdng khong co trieu chirng, khi xuat hien trieu chirng ttii benh da dien bien sang mire dd thieu mau nang hdn.
4.3. fiac diem x e t nghiem cua benh nhi thieu mau thieu sat „ , , ,
4.3.1. Dac dle'm dong hong cau vdi cac nhom nguyen nhan gay Isenh
Ket qua bang 4, 5 cho thay sd lUOng hong cau trung binh ciia nhdm nghien ciru la 3,8±0,4, nong do Hemoglobin la 73.2 ± 14.3, the tfch trung binh ciia hong cau, lUdng huyet sac to trung binh hong eau va nong dp huyet sae to trung binh eiia hong cau deu giam. Chf cd ty le phan tram hong cau lUdi va phan bo kfch thUde hong cau tang cao. Gia tri trung binh ciia MCV d benh nhi la 62.4 ± 11.2 (fl) va gia tri trung binh ciia RDW d benh nhi la 20.3 ± 3.3 (%), dayja nhD'ng chf so cd ban giiip eho djnh hudng ehan doan benh nhi bi thieu mau la do thieu sat.
Ket qua bang 6,7,8 cho thay the tfeh trung binh cua hong cau rat thap. Nhdm phoi hdp cac nguyen nhan gay benh ed 9 benh nhi chiem 100% cd mUc dp I^CV < 80 (fl). TUdng tU d eae nhdm nguyen nhan gay benh khae, mUe dd MCV
< 80 (fl) ehiem tren 80%. Khdng ed benh nhan nao cd mUe MCV > 100 (fl). LUdng huyet sac to trung binh ciia hong eau eho ket qua: 100%
benh nhi ed miTc dp MCH < 28 (pg).
4.3.2. Dac diem chuyen hda sat d cac nhdm nguyen nhan gay benh
a. Sat huyet thanh: Trong nghien eiTu nay, ehi so sat huyet thanh trung binh d tre em la 2.9 ± 2.0 (pmol/l). Chirng t d dai da sd benh nhi den vien vdi tinh trang thieu mau nang. Cu the d bang 9, 96.5% benh nhi co lUdng Fe huyet thanh < 7(pmol/l). Cd 2 trUdng hdp cd sat huyet thanh trong gidi han 7-27(Mmol/l), khdng ed trUdng hdp nao ed nong dp sat huyet thanh
>27(pmol/l). Dieu nay ed the cho thay benh nhi da thieu mau nang va keo dai. NhU vay xet nghiem sat huy€t thanh se ho trd eho chan doan ma chUa phan anh ehinh xac mu'c dp thieu mau thieu sat.
VIETNAM MEDICAL JOURNAL N°1 - FEBRUARY - 2018 b. Ferltln huyet thanh: Ket qua nghien culi
cho thay, nong dd trung binh eua ferritin d tre em la 6.7 ± 6.4 (hg/ml). Trong do ed den 86%
benh nhi cd nong do ferritin < 15 (ng/ml). Theo ket qua nghien cu'u eiia N.T.T. Ha thi ty le nay la 88%, tae gia H.T.T. Anh la 78.6%. Cd sU khac biet ve nong do ferritin giO'a nhdm chay mau vdi nhdm khdng cimg cap dii sat - kem hap thu va nhdm chay mau vdi nhdm phoi hdp d ngUdi Idn.
c Transferrin: Nghien euU cho ket qua vdi nong dd transferrin trung binh d benh nhi la 349.6 ± 6 5 . 2 (mg/dl). Nong dp transferrin > 250 (mg/dl) d tre em la 94.7%, trong dd nhdm khdng cung cap dii - kem hap thu sat va nhdm phdi hdp chiem 100%. Khdng cd trUdng hdp nao ed nong dp transferrin <200 (mg/dl). Cd den 97.1% benh nhi ed nong dp transferrin > 250 (mg/dl) thupc nhdm chay mau, tiep theo la nhdm phoi hdp vdi 93,2%, nhdm khdng cung cap dii va kerri hap thu sat la 92,3% edn nhdm ehu^ rd nguyen nhan la 91.3%.
V. KET LUAN
- Cac trieu chirtig lam sang ndi bat: Trieu chu'ng met mdi d nhdm chay mau va nlidm phdi hdp chiem 100%, d nhdm chUa rd nguyen nhan clil ed 52.4%; 100% benh nhi co trieu chii'ng da xanh niem mae nhdt; Trieu chutig nhip tim nhanh gap t / le cao tir 71,4 % trd len.
- Cac trieu chiTng can lam sang ndi bat; Mire iJ6 thieu mau la pho bien (Hb: 73,2 ± 14,3); Gap ty Ig 93% benh nhi cd mu'c MCV nhd hdn 80 fl; c6 100% tre cd nong dp MCH <28 (pg); cd 95,5%
mUc dd sat huyet thanh < 7pmol/l; cd 86% m lUdng ferritin<15ng/ml; lUdng Transfernn tang cao.
TAI Ll|U T H A M KHAO
1. WHO (2001), Iron deficiency Aneamia, Assessement, Prevention and control, A guide for programme managers, WHO, 1-114
2. Mai Lan (2015), Nghien cuV mo hinh benh mau va cd guan tao mau d benh nhi dWdc dieu tri tai Vien Huyet hoc Truyen niau Trung udng giai doan 2013 - 2015, Luan van tot nghiep bac sy chuyin khoa cap I I .
3. Hoang Thj Tram Anh (2014), Nghien cuU dac diem iam sang^ can lam sang va nguyen nhan'd benh nhan thieu fnau thieu saf &/ banh vien Bad) Mai nam 2014, Luan van thac sy y hpc.
1. Pappas DE (1998), "Iron deficiency anemia';
P^iatncs In review, tr. 321-322.
5. Npuyin Cong Khanh (^2008), Huyet hoc lam sang nhi khoa, Nha xuit ban Y hoe, 73 o. Pham Thj Lan HUdng (2016), Nghien cu'u dk
diim lam sang, xet nghiem cua benh nhi thieu mau thieu sit dieu trj tai Vien HH-TM TW giai doan 2015-2016, Khda liiari tdt nghiep bac syda khoa.
7. WHO (2011), Hemoglobin concentrations for the diagnosis of anemia and assessment of severity Vitamin and mineral nutrition information s)^em Geneva. World Health Organization.3,55-89,91-
DAC DIEM LAM SANG VA CAN LAM SANG CUA SAN PHU DUgC KHd"! PHAT CHUYEN DA TAI BENH VIEN PHU SAN TRUNG U'aNG
T O M TAT
Muc tieu: M6 ta dac diem lam sang va can lam sang cua san phu dUdc khdi phat ehuyen da tai Benh vien Phu san Tnjhg udng. Phddng pha/j: Nghien ciru tien cUu thUc hien tren 65 sanjDhu cd tudi thai tir 37 - 42 tuan dUflc klidl phat chuyen da tai khoa de Benh vien Phu s^n Trun^ Udng. Kit qui: Chi so Bishop trUdc khi gay ehuyen da trong nghien cUu eiia ehiing toi thap nhat la 1 diem, cao nhat la 5 diem. Chi so Bishop trung binh la 3,42 ± 1,31 diem. Nhom san phu cd chi so 61 > 60mm chiem t^ le Idn nhat la 69,23%.
Nhom san phu con oi chigm ty ie 87,69%, nhdm san phy cd tinh trang oi v9 ehiem ty le 12,31%. Tuoi thai 40 - 41 tuan co 53 trUdng hdp chiem ty le 82,54%.
Ket luan: San phu dUdc khdi phat ehuyen da co chi
*Benh vien Phu san Trung ddng Chiu trach nhiem chfnh: Nguyen Quang Bae Email: [email protected] Ngay nhan bai: 1.11.2017 Ngay phan bien khoa hoc: 22.12.2017 Ngay duyet bai: 28.12.2017
Nguyen Quang Bac*, Pham Thi Yen*
so Bishop trung binh la 3,42 ± 1,31 diem va phan Idn cd tudi thai tU 40- 41 tuan.
Td khda: Chi so Bishop, chi so oi, khdi phat chuyen da.
SUMMARY
CLINICAL AND SUBCLINICAL CHARACTBRISnCS OF LABOUR INDUCnON I N NATIONAL HOSPITAL
OF OBSTETRICS AND GYNEACOLOGY Objective: Tc describe dinieal and subdinical characteristics of labour induction in National hospital of Obstetrics and Gyneacology, Methods: This Is cross sectional study among 65 pregnant women with 37 to 42 gestational age who were induced labour actively. Results: Beforelabour induction, Bishop score was ranging from 1 to 5 and mean score was 3,42 ± l,3n. There was 69,23% in group of amnionic fluid index under 60mm. Chorionic sac was still intact was 87,69%. Gestational age ranging from 40-41 was 82,54% (53 cases). Conclusion: Pregnant womai wffe induced labour whose mean Bishop score was 3,42±1,31 and mostly from 40 to 41 week of gestation.