Vietnam Journal of Physiology 16(3), 12/2012 ISSN: 1859-2376
Nguyen Thi Lam, Nguyen Quoc Anh National Institute of Nutrition Received 19 October 2012; revised 24 October 2012; accepted 15 November 2012 A high salt (NaCI) Intake is a risk factor for hypertension. Over a decade there has been no study widely evaluating the salt intake of Vietnamese people while hypertension Is increasing. The present study purposely assessed sodium cion'de intake In seasoning in adults living in Hanoi city, Thua Thien Hue province, and Ho Chi Minh city. This was a cross- sectional study conducted In 2008 - 2009. A total of 1518 subjects aged over 20 participated in the study. Seasoning intake was evaluated by weighing method at household. Sodium content in seasonings was assessed by high-performance liquid chromatography (HPLC) method, then sodium salt content in the seasoning was calculated
based on molecular weight of NaCL Therefore, sodium salt Intake was equal to amount of seasonings multiplied with the content of sodium salt in the seasonings. The results showed that, mean sodium salt intake In studied subjects was 11.7 ± 5.5 g/day. No significant difference of salt intake between subjects living in urban and rural areas. Mean sodium salt intake In males (12.7 g/day) was higher than that In females (10.5 g/day) (p < 0.05). The salt intake was highest in Thua Thien Hue (12.3 g/day), followed by Ho Chl Minh city (11.1 g/day) and Hanoi (10.7 g/day). Thus, sodium salt intakes in adults in studied sites were 2 times higher than that recommended by World Health Organization.
Intervention studies should be done in the future to reduce salt intake in order to control high blood pressure in community.
Key words: sodium salt intake, adult
K H A O S A T D A C TINH OAN H 6 1 B Q N G MACH C H O CT NGUdl T^P LUY|N T H 6 Dye i n e THAO BANG SIEU AM TIM
Ld Nguyin True Quynh. Nguyin Thj Thiiy Hdng D^i hQC Y Dugc Hui Nhdn bdi 22/10/2012; sCfa bdi 26/10/2012; chip nhdn ddng 7/11/2012 Si/ gidm ddn hdi ddng mgch ho$c si/ gia tSng dd ciing ding mach diin biin theo tudi vd Id yiu td nguy co b$nh tim mach. Nhiiu nghidn cO-u cho thiy ngudi ho^t d^ng thi li/c tin suit bdnh tim mach gidm thip han so vdi ngirdi khdng /logf ddng, st/ gia tSng dd cCmg ding mgch khdng cd hoSc gidm rd d ngudi choi cdc mdn SCK bin. Myc tidu cua nghidn cCru ndy Id xdc dinh cdc chl sd ddn hdi ddng mgch chu (DMC) trdn ngudi t$p luy$n thi thao vd mdi tuang quan vdi chi si khdi CO thit trdi. Nghidn cOv dugc tiin hinh trdn 46 ngudi t$p luyin thi thao, tudi tmng binh 31,3 ± 11,4, cd so sdnh vdi 60 ngudi nhdm chCmg. Tit cd diu dugc sidu dm tim do dudng kinh ddng mgch chO k9 tdm thu vd tSm tniung, khdi ca thit trdi Xdc dinh chfsd di? cung ddng mgch chO, sue cdng dOng mgch chO, chlsd giSn vd mdi tuong quan cOa chOng vdi chlsd kb6i ca thit trdi Kit qud cho thiy sOc cSng DMC vd chl sd giSn nd d nhdm t$p luy$n cao han so vdi d nhdm chCmg c6 y nghTa thing kd (p < 0,01, p < 0.05). Chfsd dd cCmg DMC khdng khic bidt g,Q^ hai nhdm. Cht sd gidn nd DMC vd sue cdng DMC Q? 1$ thu$n vdi chf sd khdi ca thit trdi.
Khdng cd mdi lidn quan giO-a chi sd d0 cdng DMC vdi khdi 6a thit trdi. Nhu v$y. tip luyin thS thao cd Igi trdn dd ddn hdi DMC vd do dd gidm nguy ca b$nh tim mgch.
TCf khda: ddn hdi ding mgch chO. khdi co thit trdi. ngudi tip luydn thi thao
V i e t n a m J o u r n a l of Physiology 16(3), 12/2012 I S S N : 1 8 5 9 - 2 3 7 6
I.DATVAND^
e $ c tinh ddn h i i ddng mgch chO {BMC) thay d i i theo tuoi, cdng Idn t u l i ddng mgch (OM) cdng gidm ddn h l l , nghTa Id gia tdng dd Cling cOa ddng mgch, D i l u ndy Idm tdng t i n s u i t bdnh ly tim mgch theo t u l i [2], [5].
S y gla tdng dd cCpng ddng mgch chu Id yeu t l nguy c a ddc ldp cho s y phdt t r i l n x a vQ'a vd bdnh tim mgch. TO dd t i l n t r i l n d i n bdnh tdng h u y i t dp, phi dgi t h i t trdi, n h l i mdu ca tim vd suy tim xung h u y i t [4], [9].
S y hogt ddng t h i lye d l u d$n dd chOng minh cd t h i Idm giam dd ci>ng DMC d* ngud-l trd cQng nhu d* ngudi Idn t u l i . Qua dd, sd gidm nguy ca bdnh tim mgch bdng cdch Idm chdm hodc ngdn ngCra qud trtnh gia tdng dd cO-ng DMC theo tudi [7], [10].
Sidu dm tim Id xdt nghidm khdng xdm nhdp, dan gian. khdng nhung giup nghidn cCru hinh thdi vd chuc ndng tim md cdn cd t h i ddnh gla ddc tinh ddn hoi ddng mgch chd thdng qua cdc d i f s6 v l sue cdng, dd cipng DMC [1], [11],
CJ n u d c ta chua c6 n h i l u nghidn ci>u v l v i n d l ndy, vi vdy, chung tdi t h y c hidn d l tdi nay n h l m mgc tidu xdc dinh cdc chl s6 ddn hdi cua ddng mgch chu va m i i lidn quan vd'i k h i i c a t h i t trdi d ngudi tdp luydn t h i thao b i n g sieu dm tim gdp p h i n ddnh gid nh&ng thay doi tim mgch trdn ngudi tdp iuydn, so sdnh vdi ngudi binh t h u d n g khdng tdp luydn.
2. B 6 | Tl/QrNG V A PHLPaNG PHAP NGHIEN CIJU
2 . 1 . D d i tu'ang nghi§n cO'u
- Nhdm nghidn cOu: 46 ngudi khde mgnh, t u l i d u d i 45, tdp iuy$n t h i dye t h i thao d l u ddn hang ngdy d' cdc Cdu Igc bd t h i thao hodc cdc dja ffdm t u do cua thdnh p h i Hud.
T i t ca d l u cd thdi gian tdp luydn trdn 2 ndm.
- Nhdm chCrng: 60 ngudi khde mgnh, cd khdm s u e khde dinh kJ hdng ndm, khdng tham gia bat kJ mdn t h i thao nao, cd phdn b l t u l i vd gidi t u a n g d u a n g vd'i nhdm nghidn ci>u.
Cdc d i i tupng d u p c gidi thich d i y du vd d i n g 9 thyc hidn.
- TIdu c h u i n logi trO: hot t h u l c Id, r l i logn lipid mdu, dang m i c b$nh d p tinh hodc cdc bdnh \^ tim mgch khde dnh h u d n g d i n nghidn ci>u.
2.2. P h u v n g phdp n g h i d n cOu 2.2.1. Phu'cng t l ^ n nghidn ciVu
Phdng Sidu dm tim Bdnh vidn trudng Dgi hpc Y Dupc H u i , vdi mdy sidu dm Phillips,, d l u dd 3,6 MHz cd k h i ndng cho hinh dnh sidu dm TM, 2D, Doppler mdu, Doppler xung, Doppler lidn tgc. d n g nghe vd mdy do huyit dp ALK2 do Nhdt Bdn sdn x u i t , cdn bdn Trung Qude cd g i n thudc do dd hi$u chtnh.
2.2.2. P h u v n g phdp thijpc h i ^ n
- Do cdn ndng, chilu cao d l tinh di$n tich da vd chT s i k h i i ca t h i .
- Do t i n s i tim (TST), do h u y i t dp (HA) 6- t u t h i n g i i , chdn ddt trdn sdn nhd, tay ddt tren bdn ngang muc tim sau khi nghi ngai trdn g h i hodn todn. do cung thdi d i l m t i l n hdnh sieu dm tim.
- T i l n hdnh do trdn sidu dm tim: ddt d l u dd d lidn s u d n 2, 3 canh Crc trdi, khao sdt toan bd tim qua sidu dm hai binh dien theo mgt cdt cgnh i>c tryc dpc, tryc ngang, s u dyng hai nhdt cdt M-mode qua thdt ghi d b d t y do cua van hai Id va nhdt cdt qua DM chu Idn.
Do theo khuyin cdo Hdi Sidu dm Hoa KJf (American Society of Echocardiography) [3]:
dudng kinh t h i t trdi c u l l ldm truang (LVDd), t h i t trdi c u l i tam thu (LVDs), c h i l u ddy vdch lidn t h i t c u l i tdm t n j a n g (IVSd), c h i l u day vdch lien t h i t c u l i tdm thu (IVSs), c h i l u ddy thdnh sau t h i t trdi c u l i ldm truang (LVPWd), e h i l u ddy thdnh sau t h i t trdi c u l i tdm thu (LVPWs), dudng kinh nhT trdi. D u d n g kinh ddng mgch chO (AOD) d u p c do trdn mi>c van DMC khoang 3 cm t u b d tnj'dc thdnh trud'c d i n b d trudc thdnh sau cua DMC, do d 3 chu ky tim lien t i l p vd l i y trj s6 trung binh:
+ Dud-ng kinh DMC tdm truang (AODd) d u p c do d khdi d l u phirc b0 QRS.
Vietnam Journal of Physiology 16(3), 12/2012 ISSN: 1859-2376
+ Butmg kinh BMC tam thu (AODs) a w e (Jo tif dTnh vjn flOng tir b& trudc thSnh tru'dc din bti sau thinh sau cOa DMC, tCr phCfc bO QRS aki\ vj tri cu4i cCing cDa s6ng T trSn dljn tim luc van BMC m6 hoSn toSn.
2.2.3 Cic th6ng s i thu Ihjp Irong nghlSn CU'U
- Ch! s4 aanh gii sv « n hii BMC. Sv a4n hii cOa BMC du'p'c xSc dinh tCr ba chf s i : + SU'C cang BMC (Aortic strain) (%):
Sl>0 cang A0% = (AODs-AODd) « 100 /AODs [111
+ Chl s i at) cCrng cOa DMC (Aortic stiffness) [8]:
DO cCmg AO = log (HATT/HATTr)/[(AODs- AODd)/AODd]
Sv giim tinh dSn hii khi tSng at) ci>ng vi giam sVc cSng dOng mach chu.
+ ChT s i gian nd DMC (Aortic distensibitity) (cm''.dyn-'.10'')[11].
Chl s i gian n i AO = (2xAortic strain)/(HATT- HATTr)
+ HATT - HATTr: dp Ivc m?ch (mmHg) - BSnh gia khii co thit trai [3]: Chl s i khii co thit trai qua siau am tim; theo HOi si6u am Hoa Ky:
+ Tinh khii Ivong co thit trai (LVM):
LVM=0,8x{1,04x((LVDd+LVPWd+IVSd)3- (LVDd)3)) + 0.6 g
Blnh Ihvftng: nO 67+162 g; nam 88+224 g + Tinh cM s i khii Cff I h i (LVMI): LVMI = LVM/BSA (g/m2)
2.3. XCP ly s i ll^u
cac kit qui dvoc xi> ly theo phvong phap thing k6 y hoc thOng thvdng. Kit qui dvoc thi hi$n dvdl dang gia trj trung blnh va dO lOch chuin. Dijng test t-Student so sanh kit qu5 thu du'p'c, c6 y nghla khi p < 0,05.
3. K£T QUA NGHIEN COU 3.1. B$c dlim hai nhdm nghiSn cfru Bang 1. Dac diim chung v i cac dii tvong nghi§n cCru.
ThOng s i Tuii
Gidi Nam
NO BMI (kg/m^) BSA (m')
Tin s i tim (chu ky/phut) HATT (mmHg) HATTr (mmHg) Ap Ivc mgch (mmHg) M6n tap luyan: Di bO Boi lOi Aerobic Karatedo
Nhdm tap luy$n (n = 46) 31.32 ±11,43
30 (65,2%) 16 (34,8%) 21,12 ±2,26
1,57 ±0,2 62,2 ± 5.4 115,5 ±8,28
68,2 ± 6,4 47,3 ± 3,4 22 (47,8%) 6(13,05%) 6(13,05%) 12 (26,1%)
Nhdm chvng (n = 60) 32,53 ± 8,28
38 (63,3%) 22 (36,73%) 21,18±2,61 1.55 ±0.16 69.93 ± 5,83 114.42 ±8,1 66,25 ±6,16 48.3 ± 3.5
P
>0,05
>0.05
>0.05
>0,05
>0,05
<0,05
>0,05
>0,05
>0,05
0 cd hai nhdm nghidn cCru dlu khdng cd truong (p > 0,05). Ridng t i n s6 tim d nhdm sy khac bidt v l tuli, gidi, chilu eao, cdn tdp luy§n thip han so vdi"6 nhdm chung cd J ndng, huyit dp tdm thu vd huyit dp tdm nghTa (p < 0,05). Mdn t$p luydn chu ylu Id
12
Vietnam Journal of Physiology 16(3), 12/2012 ISSN: 1859 - 2376
mOn sCrc ben chiim ty 10 73,9% (di bO, boi, 3.2. BJc diim dl) din h i i djng m?ch chu aerobic). cua hai nhdm nghiOn cvu
Bang 2. Dac diim dO dan hii dOng mach chO d dii tvvng nghiOn ci>u.
ThOng s i Budng kinh DMC tam thu (AODs) (mm)
Budng kinh BMC tam tm-ong (AODd) (mm)
Sue cang BMC (%) DO ci>ng DMC
Chl sO gian nd DMC (cm'.dyn'. 10"^)
NhOm tap luy^n (n = 46) 28,1 ± 2,23 25,3 ±2,12 11,06 ±0,05 4,43 ±1,64 6,78 ±1,4
Nhdm chCrng (n = 60) 27,12 ±3,52 24,69 ± 3,44 10,9 ±0,02 4,56 ±1,68 5,13 ±1,64
p
>0,05
>0,05
<0,01
>0,05
<0,05
Nhdm tdp luydn cd AODs, AODd Idn han so chi>ng (p < 0,01, p < 0,06) DO cupng Widng khde vdi d nhdm chCrng nhung khdng cd y nghTa nhau gitta hai nhdm nghien ci>u (p > 0,05).
thong ke (p > 0,05). Si>c cdng vd chi sd gidn na 3.3. Mdi tirang quan gifpa d$ ddn h&i dpng d nhdm tdp luydn cao hon so vdi d nhdm mgch chu vdi chi s6 khdi ca thit trdi.
Bang 3. Khii ca thit trdi 6 hai nhdm nghien ci>u.
Thong s i Khoi CO that trai (LMV)(g) Chi s i khii co thit trai (LMVI) (g/m^)
NhOm tap luyOn (n = 46) 145,16 ±35,21
92,46 ±18,18
Nhdm Chung (n = 60) 112,78 ±35,13
72,33 ±19,76 P
<0,01
<0.01 Kit qua d bang 3 cho thiy. khii co thit luyOn cao hon so vdi d nhdm chvng c6 y trai va chi s i khii co that trSi d nhom tap nghTa thing kO (p < 0,01).
Bang 4. Tuong quan giOa chT s i khii co thit trai va chi s i dOn hii DMC d nhdm tOp luyOn.
ChT s i Si>c cang (%) ChTsidOcCrng
ChT s i gian nd (cm^.dyn"' .10"^)
Chl s i khii CO thit trai (g/m^) r
0,4 -0,16 0,44
P
<0,05
>0,05
<0,05
V i e t n a m J o u r n a l of P h y s i o l o g y 16(3), 12/2012 I S S N : 1 8 5 9 - 2 3 7 6
Qua bdng 4 t h i y rd d nhdm tdp luydn, sice cdng vd chf s i glfln n d DMC cd m i l tuang quan thudn vCra v d i chl s i k h i i c a t h i t trdi (p <
0,05), trong khi dd cd m i l luang quan nghjch giOa chl s i dd cCrng vdl chl sd k h l l ca t h i t trdi nhung khdng cd y nghTa t h i n g kd (p > 0,05).
4. BAN LUAN
Cdc d i i t u p n g tham gia vdo nghidn cO'u d l u c6 dO t u l i d u d i 45. Theo n h i l u nghidn eCru. t u l i edng cao thi thdnh DM cdng ddy vd tinh gidn nd' cua D M cdng g l i m , do dd Idm gidm tinh ddn h l l cua D M [2], [10]. VI vSy, d l trdnh dnh h u d n g cua t u l i tdc ddng Idn c l u trCic vd chCrc ndng cua DMC chCing tdi chpn Id-a t u l i ndy. Trong nghlSn cO'u chQng tdi cOng chpn nhQ'ng d i i tup'ng cd ch? s i k h i i ca t h i (BMI) trong gidi hgn blnh thudng vl thCj-a cdn vd bdo phi cQng dnh h u d n g Idn dd ddn h i i DMC. ChOng tdi chpn vdo nghidn ci>u nhdm tdp luydn vd nhdm chi>ng cd ty id v l gidi tuang d u a n g nhau vi s y khde bi|t v l gidi cDng anh hudng d i n k i t q u i nghidn cCru [2].
T i n s i tim cua nhdm tdp i u y i n t h i p han so vdi d" nhdm ehijpng cd y" nghTa t h i n g kd (p <
0,05) vd t i t ca d l u a gidi hgn binh thud-ng.
Nhu vdy khi dd huyet dp se khdng anh hud-ng bdi xue cam hay lo l i n g gdy thay d i i trj s i h u y i t dp. Chdm t i n s i tim khi nghi thudng ghi nhdn d* n g u d i tdp luy$n, ddy Id s y thay d i i t i t cho hogt ddng tim, tim hogt ddng cd hidu qua vdi tdng t h i tich t i n g mdu, t i l t ki$m ndng luang, k i t qud cua s y tdng truang tyc phd giao cam khi nghi [8]. HATT vd HATTr d hai nhdm khdng cd s y khde bldt (p > 0,05).
Dd ddn h i i DMC t i t khi giSm dd cO-ng DMC, tdng si>c cdng vd tdng chl s i gidn n d DMC tdng. cdn ngugc Igi Id dd ddn h i i DMC giam. Dd cO-ng DMC d u p c xem nhu Id y l u t l nguy ca cQa b$nh tim mgch [4], [5]. Trong nghien c u u ndy, chijng tdi t h i y r i n g , d nhdm tdp luy$n d u d n g kinh DMC tdm thu vd tdm t r u a n g cQng n h u dd eung D M C khdng khde bi$t cd ^ nghia so vdi d nhdm Chiang, nhung si>c cdng D M C vd chT s6 gidn n d DMC cao h a n c6 y nghTa so vd'i d nhdm
ChOng (p < 0 , 0 1 . p < 0,05). Maidonado vd es.
nghidn cOu trdn 212 vdn ddng vidn, so sdnh vd'i 211 n g u d i blnh thud^ng khdng tdp luydn, ghi nhdn chT s i ddn h l l ddng mgch ehu t i t han d n g u d i t$p luydn, d i l u ndy p h i n dnh sy phdt t r i l n t i t chO'c ndng ndi mgc. Nh&ng thay d i i thudn Ipl ndy ddc ldp vdl tudi, t h i y rd ngay cS d n g u d l cao t u l i cd tdp luydn t h i thao [6].
Seals ghi nhdn ngud'i tdp luydn t h i thao d l u ddn, ddc bl$t cdc mdn sOc b i n , sd gidm ho$c f i t It suy gidm chCrc ndng DM theo t u l i , duy tri ehCrc ndng nOi mgc ti> dd gidm nguy co bdnh mgch vdnh [10].
K i t qud ndy cua chung tdi cOng phCi hpp vd'i k i t qud cOa mdt s6 tde gid nudc ngodi khde n h u D'Andrea (4], Tanriverdi [12], Tanrlverdl nghidn cO-u frdn 56 vdn ddng vidn sOc b i n , so sdnh vd\ 46 n g u d i nhdm chOng, ddnh gid ddc tinh DMC qua sidu dm tim. ghi nhdn chl s i gidn nd', sOc cdng d l u tdng d VDV (5,8 ± 2,7 so vd'i 4,7 ± 1.3 cm^dyn vd 12.3 ± 2,4 so vd'i 9,3 ± 3,1), cdn ehf s i ci>ng Igi gidm (4,8 ± 1 , 9 so vd'i 6,1 ± 2 , 1 ) (12].
Tuy nhidn, khi nghidn cO'u ddc tfnh ddn h i i DMC 6' cdc logi hinh tdp luydn khde nhau n h i l u tdc gid ghi nhdn. cdc mdn d i i khdng Idm tdng dd cOng D M C , d i l u ndy gdy tdng hdu gdnh [4], [7], [12]. ROnnback ghi nhdn, d n g u d i ldp cdc mdn s u e b i n d l u ddn s§ gidm nguy c a cO-ng ddng mgch theo t u l i . Ngupc.
Igi. ede mdn t h i thao d i i khdng Idm tdng dd cOng ddng mgch vd tdng dp lye mgch [9].
Trong nghidn cO-u cua chOng tdi cd s i ngudi tdp luydn cdc mdn sOc b i n c h l l m da s6 (73,9%). do dd s y thay d i l theo c h i l u hudng c6 lpi trdn chO-c ndng D M Id phO h y p vd'i cdc nghidn cO'u trdn t h i gid'i. Cdn chT s i dO cOng khdng khde bidt giO-a hai nhdm nghidn cOu.
Ddy Id mdt gid'i hgn cua nghidn CCFU n l u gdP Igi cdc logi hinh t h i thao khde nhau, vi vdy ehung tdi sd t i l p tge nghidn cOu thdm d§c llnh ddn h i i DMC * ngud'i tdp luydn mdn d i i khdng vd'i mSu Idn h a n . TO dd cd t h i so sdnh ddc tinh ddn h i i D M C & cdc logi hinh tdp luydn khde nhau.
V i e t n a m J o u r n a l of Physiology 16(3), 12/2012 I S S N : 1 8 5 9 - 2 3 7 6
Nghien cOu cOa chung tdi ghi nhdn, k h i i c a t h i t trai d nhdm tdp luydn Idn han so vdl d nhdm ehCng ed '^ nghTa (p < 0,01). Pluim dd t i n g hpp 59 nghign ciJu vdi 1451 vdn ddng vidn (VDV) d cdc trung tdm nghidn cOu khde nhau, ghi nhdn cd s y thay d i l hinh thdi I h i t trdi cd y nghTa. Sy thay d i i ndy giOp cho thieh nghi h u y i t ddng khi gdng sOe, n h l m tdng khd ndng vdn ehuyin oxy d i n t l chuc [9]. Nhdm d i i t u p n g tdp luydn trong nghidn cu'u chOng tdi khdng chl Id cdc VDV ehuydn nghidp md cdn Id ngudi t$p luydn nghidp d u , do dd tuy LVMI ed Id-n han so vdi d nhdm khdng t$p luydn nhung vdn trong gidi hgn binh thudng (92,45 ± 18,18 so vd'i 72,33 ± 19,76). Cd t h i do cudng dd l$p luydn chua cao, mde d l u ChO'c ndng DMC cd c h i l u hud'ng t i t han.
N h i l u nghidn cOu ghi nhdn, s y thay d i i hinh thdi that trdi t h u d n g gdp d cdc VDV nhung chuc ndng tdm thu vd tdm truang d l u blnh thudng [9]. Khde vd'i cdc bdnh ly gdy ddy t h i t trdi khde, nhu tdng huyet dp, trj s i h u y i t dp cao tdc ddng Idn DMC gay ndn cOng DM. S y cO-ng DMC tac ddng Idn lim ldm tdng gdnh t h i t trdi vd nhu e l u oxy ea tim d i n d i n gidm chOc ndng tdm t n j a n g that trdi vd v l lau dai hdu qud la tdng khoi c a t h i t trai. Nd Id mdt trong nhung nguydn nhdn chd y l u cOa suy tim [9], Vi vdy ed the t h i y gia tdng k h i i ca t h i t trdi d ngud'i tdp luydn la thich nghi sinh ly.
Tuy nhidn Pluim cQng n h i n manh r i n g cde nghidn c u u trdn chT phan anh thay doi c a hpc cua khoang tim han Id c a e h l ca tim, e h i n g han trong phi dgi t h i t trai d* b$nh nhdn tdng h u y i t dp, nhieu nghidn cOu cho t h i y khd ndng hoat ddng spi c a tim bj giam ngay cd khi phdn s u i t t i n g mdu (EF) v i n binh thudng.
Mdc dau vdy, chua cd nghidn cOu sdu han v l van d l nay d VDV [8].
N l u nhu d bdnh THA, sOc cdng DMC vd chl s i gian n d DMC tuang quan nghich vdi chl s i khdi ca t h i t trdi. ch! s i dd cOng DMC tuang quan thudn vd'i chT s d k h i i c a t h i t trdi [1], Ihi ngupc Igi Irong nghidn cOu ndy ci3a chOng tdi, d" ngud'i tdp luydn t h i thao ghi
nhdn sOc cdng vd chl s i gidn n d DMC ed m i i tuang quan thudn vd'i chT s i k h i i ea t h i t trdi (p < 0,05), trong khi dd khdng cd m i i tuang quan giOa chl s i dd cOng vdi chl s i k h i i ea t h i t trdi (p > 0,05). D l l u ndy cho t h i y s y gia tdng k h i i ea t h i t trdi Id s y thich nghi sinh ly d ngudi tdp luydn, chOc ndng tim v i n binh thudng, chOc ndng DMC cd ehilu hudng t i t han. Otsuki vd cs. eho t h i y 6 ngud'i trd tham gia cdc mdn t h i thao sO'c b i n , mde dO k h i i ea t h i l trdi ed xu hudng tdng nhung v i n gidm dd cOng DM, bdn cgnh dd, nhO-ng thay d i i dd cOng DM lidn quan d i n ede chuang trinh h u l n luydn khde nhau d ngudi trd cQng nhu ngud'i gid vd nhQ'ng thay d i i ndy cd t h i b i t d l u ti> thanh t h i l u nidn [7]. D'Andrea vd es.
ghi nhdn chl s i gidn n d DMC cao han d VDV sOc b i n ehuydn nghi$p so vdi d" nhdm chOng [4]. TO cdc nghien cOu tren, cd the t h i y cdc mdn t h i thao sue b i n (di bd, bai Idi, chgy ddi...) cd lpi cho chuc ndng DM d ngudi tre l l n ngudi Idn t u i i muon tham gia tdp luydn Vne thao de cai t h i i n sOc khde vd keo ddi t u i i thp cua minh.
5. KtT LUAN
- Sue edng, chl s i gian n d DMC d' nhdm tdp luydn cao han cd y nghTa so vdi d" nhdm ehOng (p < 0,01, p < 0,05). Od cOng DMC khdng khde bi^t giOa hai nhdm nghien cOu.
- Cf nhdm tdp luydn, cd m i i tuong quan thudn giOa sOc cdng DMC, chi s i gidn n d DMC vdi chi s i k h i i c a t h i t trdi (p < 0,05), khdng cd m i i tuang quan giO'a dd cOng DMC vd chi s i k h i i c a t h i t trdi ( p > 0,05).
T A I L ( $ U THAM K H A O
1. Nguyin Thj Hiiu Dung, Nguyin Thj Thuy h i n g (2011) Khdo sdt s u ddn h i i ddng mgch chO d bdnh nhdn Idng huyit dp nguyen phdt bing sidu dm lim. Tgp chl Y Dupc hpc.
Tnjd'ng Dal hpc Y Dupc H u i , s i 2.
2. Dinh Thj Thu Huvng (2008) Tim hllu dnh hudng cua t u i i tdi dO cOng cda ddng mgch.
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SUMMARY
Evaluation of aortic elastic properties o n the s p o r t s p e r s o n by e c h o c a r d i o g r a p h y
Le N g u y e n True Q u y n h , Nguyen Thi T h u y Hang
^ u e University of Medicine and Pharmacy
Received 22 October 2012; revised 2i October 2012; accepted 7 November 2012 A decrease In arterial compliance or an increase In arterial stiffness Is common with advancing age and it Is a predictor ol cardiovascular risk factors. Epidemiologhai studies have found that physically active person have lower prevalence ol cardiovascular disease compared to sedentary. It has been reported that age- related increases in central arterial stiffness are absent or attenuated In endurance-trained adults. The purpose of this study was to estimate the indexes of aortic elasticity In the sportsperson and the correlation between them and left ventricular mass index. This study was carried on 46 sportsperson, their mean age of 31.3 ± 11.4 and compared with the sedentary healthy control group of 60 people. They are all under echocardkigraphy to measure systolic aortic diameter and diastolic aortic diameter, left ventricular mass, and left ventricular mass index. Then, assess the indexes such as: aortic strain, aorta stiffness, aortic distensibiiity and correlatk>n between them and left ventricular mass index.
The results showed that aortic strain and aortic distensibiiity were slgnificantfy higher in the active group compared with those in the sedentary people. There was no difference in aortic stiffness index be/ween Ote sportsperson and healthy sedentary group.
There were positive correlation between left ventricular mass index and both aortic strain and aortic distensibiiity. In contrast, there is no correlation between aortic stif^ess and left ventricular mass index. Thus, physical activity may have beneficial eflfecte on arterial elasticity, therefore reducing the risk of cardhvascular disease.
Key words: aortic elasticity, left ventricul&
mass, sportsperson
