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January 2018, Vol. 108, No. 1

FROM THE EDITOR

3 Alcohol harms – the next challenge B Farham

IZINDABA

4 30 days in medicine B Farham OBITUARIES 5 Johan Benjamin Janeke

M van Dyk

6 Christopher John Bretherton Hundleby S Sellars

CONTINUING MEDICAL EDUCATION

GUEST EDITORIAL 8 Bleeding disorders (part 1)

N Alli ARTICLE

9 Inherited bleeding disorders

N Alli, J Vaughan, S Louw, E Schapkaitz, J Mahlangu

IN PRACTICE

COCHRANE CORNER

16 Nutritional supplements for people being treated for active tuberculosis: A technical summary L Grobler, S Durao, S M van der Merwe, J Wessels, C E Naude

MEDICINE AND THE LAW

19 ‘Covering doctors’ standing in for unavailable colleagues: What is the legal position?

D J McQuoid-Mason CLINICAL UPDATE

22 A cool ECG

S Lahri

RESEARCH

23 South African clinical practice guidelines: A landscape analysis

M Wilkinson, T Wilkinson, T Kredo, K MacQuilkan, C Mudara, A Winch, Y Pillay, K J Hofman 28 Opportunities to optimise colistin stewardship in hospitalised patients in South Africa: Results of

a multisite utilisation audit

A P Messina, A J Brink, G A Richards, S van Vuuren

33 Self-reported alcohol use and binge drinking in South Africa: Evidence from the National Income Dynamics Study, 2014 - 2015

N G Vellios, C P van Walbeek

40 Prevalence of tobacco use in selected Johannesburg suburbs J A Teare, N Naicker, P Albers, A Mathee

45 Predictors of treatment success in smoking cessation with varenicline combined with nicotine replacement therapy v. varenicline alone

F Noor, C F N Koegelenberg, T M Esterhuizen, E M Irusen

50 Good correlation between the Afinion AS 100 analyser and the ABX Pentra 400 analyser for the measurement of glycosylated haemoglobin and lipid levels in older adults in Durban, South Africa N S Abbai, M Nyirenda, T Reddy, G Ramjee

EDITOR

Bridget Farham, BSc (Hons), PhD, MB ChB EDITORS EMERITUS

Daniel J Ncayiyana, MD (Groningen), FACOG, MD (Hon), FCM (Hon) JP de V van Niekerk, MD, FRCR ASSOCIATE EDITORS

Q Abdool Karim, A Dhai, R C Pattinson, A Rothberg, A A Stulting, J Surka, B Taylor, M Blockman, J M Pettifor, W Edridge, R P Abratt, D L Clarke

HMPG

CEO AND PUBLISHER Hannah Kikaya

Email: [email protected] MANAGING EDITORS Claudia Naidu Naadia van der Bergh TECHNICAL EDITORS Emma Buchanan Kirsten Morreira Paula van der Bijl PRODUCTION MANAGER Emma Jane Couzens DTP AND DESIGN Clinton Griffin Travis Arendse

CHIEF OPERATING OFFICER Diane Smith | Tel. 012 481 2069 Email: [email protected] SALES MANAGER (CAPE TOWN) Azad Yusuf

JOURNAL ADVERTISING Reneé Hinze

Ladine van Heerden Makhadzi Mulaudzi Charmalin Comalie ONLINE SUPPORT Gertrude Fani FINANCE Tshepiso Mokoena HMPG BOARD OF DIRECTORS Prof. M Lukhele (Chair), Dr M R Abbas, Mrs H Kikaya, Dr M Mbokota, Dr G Wolvaardt

ISSN 2078-5135

SAMA website: www.samedical.org Journal website: www.samj.org.za

JANUARY 2018 VOL. 108 NO. 1

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January 2018, Vol. 108, No. 1 56 Anaemia, renal dysfunction and in-hospital outcomes in patients with heart failure in Botswana

J C Mwita, M G M D Magafu, B Omech, M J Dewhurst, Y Mashalla

61 Keeping our heads above water: A systematic review of fatal drowning in South Africa C J Saunders, D Sewduth, N Naidoo

CPD QUESTIONS

Background photo: A newborn baby at Caia District Hospital in central Mozambique |

Shaun Swingler

Box photos: Factor IX, one of the serine proteases of the coagulation system | Shutterstock;

Empty wine bottles | emily kate; Toddlers can drown in a bucket of water | emily kate

JANUARY 2018 VOL. 108 NO. 1

RESEARCH South African clinical practice guidelines:

A landscape analysis Opportunities to optimise colistin stewardship Alcohol use and abuse in South Africa Prevalence of tobacco use in Johannesburg Drowning surveillance in South Africa CME Bleeding disorders (part 1) IN PRACTICE Nutrition for TB patients A cool ECG

ISSN 2078-5135

ONLINE CONTENTS LISTED IN Index Medicus (Medline) Excerpta Medica (EMBASE) Biological Abstracts (BIOSIS) Science Citation Index (SciSearch) Directory of Open Access Journals (DOAJ) Current Contents/Clinical Medicine SAMJ SUBSCRIPTION RATES Local subscriptions ZAR 1 632.00 p.a.

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Members of the South African Medical Association receive the SAMJ only on request, as part of their membership benefit.

Subscriptions: Tel. 012 481 2071 Email: [email protected]

The SAMJ is published monthly by the Health and Medical Publishing Group (Pty) Ltd, Co. registration 2004/0220 32/07, a subsidiary of SAMA.

HEAD OFFICE

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Tel. 012 481 2069 Email: [email protected] EDITORIAL OFFICE Suite 11, Lonsdale Building, Lonsdale Way, Pinelands, 7405 Tel. 021 532 1281 | Cell. 072 635 9825 Email: [email protected] Please submit all letters and articles for publication online at

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© Copyright: Health and Medical Publishing Group (Pty) Ltd, a subsidiary of the South African Medical Association Use of editorial material is subject to the Creative Commons Attribution – Non-commercial Works Licence.

https://creativecommons.org/licenses/by- nc/4.0

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