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385 June 2014, Vol. 104, No. 6

EDITOR

Janet Seggie, BSc (Hons), MD (Birm), FRCP (Lond), FCP (SA)

EDITOR EMERITUS

Daniel J Ncayiyana, MD (Groningen), FACOG MD (Hon), FCM (Hon) CONSULTING EDITOR JP de V van Niekerk, MD, FRCR DEPUTY EDITOR

Bridget Farham, BSc (Hons), PhD, MB ChB EDITORIAL SYSTEMS MANAGER Melissa Raemaekers, BSc (Hons), PhD SCIENTIFIC EDITOR

Ingrid Nye, BSc TECHNICAL EDITORS Paula van der Bijl, BA, HDipLib Emma Buchanan, BA NEWS EDITOR

Chris Bateman | Email: [email protected] HEAD OF PUBLISHING

Robert Arendse PRODUCTION ASSISTANT Neesha Hassan ART DIRECTOR Brent Meder DTP & DESIGN

Anelia du Plessis | Carl Sampson ONLINE MANAGER

Gertrude Fani

DISTRIBUTION MANAGER

Edward Macdonald | Tel. 021-681-7085 HEAD OF SALES AND MARKETING Diane Smith | Tel. 012-481-2069 Email: [email protected] PROFESSIONAL ADVERTISING Bronlyne Granger | Tel. 021-681-7000 E-mail: [email protected] HMPG BOARD OF DIRECTORS Prof. M G Veller (Chair), Prof. M Lukhele, Dr M Mbokota, Prof. A A Stulting, Dr M R Abbas, Dr G Wolvaardt ASSOCIATE EDITORS

Q Abdool Karim, A Dhai, N Khumalo R C Pattinson, A Rothberg, A A Stulting, J Surka, B Taylor, M Blockman ISSN 0256-9574

Publisher website: www.hmpg.co.za SAMA website: www.samedical.org Journal website: www.samj.org.za

JUNE 2014 VOL. 104 NO. 6

GUEST EDITORIAL 387 Medical marijuana and beyond

J P de V van Niekerk 388 EDITOR’S CHOICE CORRESPONDENCE

389 Importance of shielding blood donors from harm E Klug, M Gebka, F Hellig, M Alison, B Townsend, V Naidoo 389 Are all fish oil supplements safe during pregnancy?

M Opperman, S Benade

390 A meaningful and sustainable outreach programme in southern Gauteng K R L Huddle, G Chita, N Naicker

IZINDABA

391 E Cape illegal immune-booster given ‘false’ approval – officials suspended 394 SAMA grasps the racial nettle, winning huge majority vote

395 Netcare – KPMG breached client privilege to boost Competitions Commission probe OBITUARY/HULDEBLYK

397 Christian George Albertyn BOOK REVIEWS

398 273 Amazing Days: The Story of Life Before Birth 398 Across the Wide Zambezi: A Doctor’s Life in Africa

SAMJ FORUM OPINION

399 Legalising medical use of cannabis in South Africa: Is the empirical evidence sufficient to support policy shifts in this direction?

C D H Parry, B J Myers CLINICAL ALERT

401 Haemophagocytic lymphohistiocytosis: A fulminant syndrome associated with multiorgan failure and high mortality that frequently masquerades as sepsis and shock B Price, J Lines, D Lewis, N Holland

ISSUES IN PUBLIC HEALTH

407 ‘Urban insight’: A high level of undiagnosed need reflects limited access to and availability of eye-care services in South Africa

A Mathee, A de la Rey, A Swart, S Plagerson, N Naicker ADVANCES IN MEDICINE

408 Additive manufacturing: From implants to organs T S Douglas

EDITORIALS

410 A reflection on the South African Medical Association – past, present and future M Grootboom, M Sonderup

411 A putative founder effect for Parkinson’s disease in South African Afrikaners J Carr, R van Coller

RESEARCH

413 Identification of a common founder couple for 40 South African Afrikaner families with Parkinson’s disease

G Geldenhuys, B Glanzmann, D Lombard, S Boolay, J Carr, S Bardien

420 No evidence for association of insulin receptor substrate-1 Gly972Arg variant with type 2 diabetes mellitus in a mixed-ancestry population of South Africa

Z Vergotine, A P Kengne, R T Erasmus, T E Matsha

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386 June 2014, Vol. 104, No. 6

Tree and the Milky Way seen from Sutherland in South Africa.

Photo and text: Eric Nathan Email: [email protected]

CONTENTS LISTED IN Index Medicus (Medline) Excerpta Medica (EMBASE) Web of Knowledge Biological Abstracts (BIOSIS) Science Citation Index (SciSearch) Current Contents/Clinical Medicine SAMJ SUBSCRIPTION RATES Local subscriptions R1 144.00 p.a.

Foreign subscriptions R2 580.00 p.a.

Single copies R95.00

Members of SAMA receive the SAMJ only on request, as part of their membership benefit.

Subscriptions: Tel. 012-481-2071 E-mail: [email protected] The SAMJ is published monthly by the Health and Medical Publishing Group (Pty) Ltd, Co. registration 2004/0220 32/07, a subsidiary of SAMA.

28 Main Road (Cnr Devonshire Hill Road), Rondebosch, 7700

Tel. 021-681-7200.

E-mail: [email protected] Website: www.hmpg.co.za

Please submit all letters and articles for publication online at www.samj.org.za

© Copyright: Health and Medical Publishing Group (Pty) Ltd, a subsidiary of SAMA Use of editorial material is subject to Creative Commons Attribution – Noncommercial Works License 3.0. http://creativecommons.

org/licenses/by-nc/3.0

Plagiarism is defined as the use of another’s work, words or ideas without attribution or permission, and representation of them as one’s own original work. Manuscripts containing plagiarism will not be considered for publication in the SAMJ. For more information on our plagiarism policy, please visit http://www.samj.org.za/index.

php/samj/about/editorialPolicies Printed by Creda Communications

424 The prevalence of hypotension and hypoxaemia in blunt traumatic brain injury in the

prehospital setting of Johannesburg, South Africa: A retrospective chart review W Stassen, T Welzel

428 Setting ART initiation targets in response to changing guidelines: The importance of addressing both steady-state and backlog

C Martin, N P Naidoo, W D F Venter, A Jaffer, P M Barker

431 Paediatric otitis media at a primary healthcare clinic in South Africa L Biagio, D W Swanepoel, C Laurent, T Lundberg

435 Tick-box admission forms improve the quality of documentation of surgical emergencies, but have limited impact on clinical behaviour

G L Laing, J L Bruce, D L Clarke

CONTINUING MEDICAL EDUCATION GUEST EDITORIAL

439 Sexual health in the South African context M M Campbell, D J Stein

REVIEW

440 Sexual dysfunction: A systematic review of South African research M M Campbell, D J Stein

ARTICLES

445 An integrative treatment model for patients with sexual dysfunctions P Ramlachan, M M Campbell

446 Female sexual dysfunction R Boa

447 Male sexual dysfunction P Ramlachan, M M Campbell

448 Hypersexual disorder in general practice M M Campbell, D J Stein

449 Transgender issues in South Africa, with particular reference to the Groote Schuur Hospital Transgender Unit

D Wilson, A Marais, A de Villiers, R Addinall, M M Campbell, The Transgender Unit 450 Sexual function and ageing

L Geffen

PROFESSIONAL ADVERTISING CPD QUESTIONS

C M Y CM MY CY CMY K

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