Inhibition of Lung Cancer Migration and Invasion Using a Gold Nano Photosensitizer Conjugate
Summary:
The aim of the research was to show that, the use of gold nanoparticles in nano-mediated PDT can cause lung cancer cell death. This study is invaluable as, irrespective of advances in cancer treatment, lung cancer remains one of the leading causes of cancer deaths worldwide.
This research is imperative as lung cancer is quite difficult to treat. It is reported in the study that PDT, a minimally invasive cancer treatment, is based on the concept of light stimulation of a photosensitizing agent at a certain wavelength. Additionally, gold nanoparticles have been shown to improve the effectivity of PDT by increasing the loading potential of the PS within cancer cells, are biocompatible and non-toxic, and give improved permeability and retention.
The introduction is clearly outlined, the materials and method section were also described in detail and the results well presented.
The results were reported to show that nano mediated PDT treatment of lung cancer inhibits lung cancer migration and invasion, causes cell cycle arrest, and reduces lung cancer proliferative abilities, elaborating on the efficacy of nano mediated PDT treatment of lung cancer.
As stated before the study is of high priority as it investigates the use of PDT as a potential therapy for a deadly type of cancer.
The paper is recommended for publication.
