1. U.A.A., SharafEl. Din, Salem, M. M. & Abdulazim, D. O. Diabetic nephropathy: time to withhold development and progression - A review. J. Adv. Res 2017, 8, 363.
2. Hershey, D.S. Diabetic peripheral neuropathy: evaluation and management. J. Nurse Practitioners 2017, 13, 199.
3. WHO. Global report on diabetes. 2016 (diakses: 06.03.2020).
https://apps.who.int/iris/bitstream/handle/10665/204871/9789241565257_eng.pdf?sequence
=1.
4. Chiang, J. L. Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes Care 2014, 37, 2034.
5. Shojaeian, A. dan Mehri-Ghahfarrokhi, A. An overview of the Epidemiology of Type 1 Diabetes Mellitus. Int. J. Metab. Syndromes 2018, 2, 1.
6. Santos, I. S., Guerra, F. B., Bernardino, L. F., Fernandes, P. D., Hamerski, L., Silva, B. V. J.
A facile synthesis of novel isatinspirooxazine and potential in vitro anti-proliferative activity. Braz. Chem. Soc. 2019, 30, 198.
7. Paul, S., Roy, A., Deka, S. J., Panda, S., Srivastava, G. N., Trivedi, V., dan Manna, D.
Synthesis and evaluation of oxindoles as promising inhibitors of the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1. MedChemComm 2017, 8, 1640.
8. Khan, M., Yousaf, M., Wadood, A., Junaid, M., ashraf, M., Alam, U., Ali, M., Arshad, M., Hussain, Z., Khan, K. M. Discovery of novel oxindole derivatives as potent α-glucosidase inhibitors. Bioorganic & Medicinal Chemistry 2014, 22, 3441.
9. Thakur, P. B. dan Meshram, H. M. “On water” highly atom economical and rapid synthesis of a novel class of 3-hydroxy-2-oxindole scaffolds under a catalyst-free and column chromatpgraphy-free protocol at room temperature. RSC Advances 2014, 4, 6019.
10. Khawandanah, J. Double or hybrid diabetes: A systematic review on disease prevalence, characteristics and risk factors. Nutrition & Diabetes 2019, 9, 33.
11. Inman, M. dan Moody, C. J. Indole synthesis-something old, something new. Chemical Science 2013, 4, 29.
12. Kaushik, N. K., Kaushik, N., Attri, P., Kumar, N., Kim, C. H., Verma, A. K., dan Choi, E.
H. Biomedical importance of indoles. Molecules 2013, 18, 6620.
13. Kumari, A. dan Singh, R. K. Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives. Bioorganic Chemistry 2019, 89, 103021.
14. Jalandra, R. dan Jadon, G. A review article on indole International Journal of Advanced Research in Pharmaceutical & Bio Sciences 2014, 4, 1.
15. Taber, D. F. dan Tirunahari, P. K. Indole synthesis: A review and proposed classification.
Tetrahedron, 2011, 67, 7195.
16. Sonawane, R. P. dan Tripathi, R. R. The Chemistry and Synthesis of 1H-indole-2,3-dione (Isatin) and its Derivatives. International Letters of Chemistry, Physics and Astronomy 2013, 12, 30.
17. Gangarapu, K. Development of Isatin as CNS Agents: Anticonvulsant Activity. 2014.
Hamburg: Anchor Academic Publishing.
18. Khan, F. A. dan Maalik, A. Advances in pharmacology of isatin and its derivatives: A review. Tropical Journal of Pharmaceutical Research 2015, 14, 1937.
19. Rudrangi, S. R. S., Bontha, V. K., Manda, V. R. dan Bethi, S. Oxindoles and Their Pharmaceutical Significance- an Overview. Asian Journal of Research in Chemistry 2011, 4, 335.
20. Silakari, O. (Ed.). Key Heterocycle Cores for Designing Multitargeting Molecules. 2018.
Patiala: Elsevier Ltd.
21. Skoog, D. A., Holler, F. J., Crouch, S. R., West, D. M., Learning., C., dan Company., B. P.
Fundamentals of Analytical Chemistry. 2014. Belmont: Brooks/Cole : Cengage Learning.
22. Schwalbe, H. Applied NMR Spectroscopy for Chemists and Life Scientists. By Oliver Zerbe and Simon Jurt. Angewandte Chemie International Edition 2014, 53, 13324.
23. Chapdelaine, P., Tremblay, R. R., Dube, J. Y.. Nitrophenol-α-D-glucopyranoside as substrate for measurement of maltase activity in human semen. Clinical Chemistry 1978, 24, 208.
BAB VII
d. Fungsional/Pangkat/Gol. : Lektor/Penata/IIIb e. Jabatan Struktural : -
f. Bidang Keahlian : Kimia Organik g. Fakultas/Departemen : FSAD/Kimia
h. Alamat Rumah/No. Telpon : Perum SPR J8/081252180161 i. Riwayat penelitian :
1. Pengembangan Senyawa-senyawa Bioaktif Baru Turunan Karbazola (Anggota) 2020 2. Pengembangan Inhibitor alfa-Glukosidase Baru untuk Pengobatan Diabetes (Anggota)
2020
3. Pengembangan Inhibitor alfa-Glukosidase Baru untuk Pengobatan Diabetes (Anggota) 2019
2. Bioaktivitas dan Konstituen Kimia dari Chromolaena odorata (Anggota) 2019
3. Bahan Material Biofarmaka baru "Santon Glikosida Termodifikasi" dari Isolat Santon Hasil Isolasi pada Dua Spesies Tumbuhan Garcinia sp. Endemik Hutan Tropis
Kalimantan (Anggota) 2019
4. Pembuatan Kapsul berbahan dasar Kitosan Larut Air dari Kitosan Komersial (Anggota) 2019
j. Publikasi :
1. Fadlan, A.; Tanimoto, H.; Ito, T.; Aritomi, Y.; Ueno, M.; Tokuda, M.; Hirohara, S.;
Obata, M.; Morimoto, T.; Kakiuchi, K. Synthesis, photophysical properties, and photodynamic activity of positional isomers of TFPP-glucose conjugates Bioorganic &
Medicinal Chemistry 2018, 26, 1848.
2. Fahmi. M. R. G.; Khumaidah, L.; Ilmiah, T. K.; Fadlan, A.; Santoso, M. 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies IOP Conference Series: Materials Science Engineering 2018, 349, 012039.
3. Wardani, E. A.; Fadlan, A.; Santoso, M. Synthesis of 2-ethoxy-1-((3-methyl-2-buten-1-yl)oxy-4-((3-methyl-2-buten-1-yl)oxymethyl))benzene AIP Conference Proceeding 2018, 2049, 020087.
4. Annur, R. M.; Titisari, D. A.; Dinarlita, R. R.; Fadlan, A.; Ersam, T.; Nuryastuti, T.;
Santoso, M. Synthesis and anti-tuberculosis activity of trisindolines AIP Conference Proceeding 2018, 2049, 020088.
5. Fahmi, M. R. G.; Fajar, A. T. N.; Roslan, N.; Yuliati, L.; Fadlan, A.; Santoso, M.;
Lintang, H. O. Fluorescence Study of 5-Nitroisatin Schiff Base Immobilized on SBA-15 for Sensing Fe3+ Open Chemistry formerly Central European Journal of Chemistry 2019, 17, 438.
k. Paten : -
l. Tugas Akhir :
1. Anis Rastiwi, 2014, Sintesis dan Bioaktivitas 3,3’-Bis(pirol-2- il)oksindola dan 3,3’-Bis(pirol-2-il)-5-fluoroksindola
2. Fatima Nuraini, 2014, Sintesis dan Bioaktivitas 3,3’-Bis(pirol-2- il)-5-bromoksindola dan 3,3’-Bis(pirol-2-il)-5-kloroksindola
2. Anggota
a. Nama Lengkap : Prof. Dr. Mardi Santoso b. Jenis Kelamin : Laki-laki
c. NIP : 196501311989101001
d. Fungsional/Pangkat/Gol. : Guru Besar/Pembina Utama MadyaI/IVd e. Jabatan Struktural : -
f. Bidang Keahlian : Kimiak g. Fakultas/Departemen : FSAD/Kimia
h. Alamat Rumah : Perum ITS V-9/085730239738 i. Riwayat Penelitian :
1. Synthesis of Commercial Fragrance Prenyl acetate: Development and Application of New Synthetic Methods (Ketua)
2. Development of The Yamaguchi Method for Synthesis of New Fragrances from Natural Eugenol (Ketua)
j. Publikasi :
1. Prayitno, B. dan Santoso, M. Biochemical activities of new isatin derivative against WiDr colon cancer Journal of Physics: Conference Series 2020, 1422, 012017.
2. Muharrami, L. K., Munawaroh, F., Ersam, T., Santoso, M., Setiawan, E., Hidayati, Y., Rosidi, I. Antibacterial Activity of Leaves Extract of Bukkol (Ziziphus mauritania Lam) against E.coli and S.aureus International Conference on Basic Sciences and Its
Applications, KnE Engineering 2019, 180–189.
3. Fahmi, M. R. G.; Fajar, A. T. N.; Roslan, N.; Yuliati, L.; Fadlan, A.; Santoso, M.;
Lintang, H. O. Fluorescence Study of 5-Nitroisatin Schiff Base Immobilized on SBA-15 for Sensing Fe3+ Open Chemistry formerly Central European Journal of Chemistry 2019, 17, 438.
4. Annur, R. M.; Titisari, D. A.; Dinarlita, R. R.; Fadlan, A.; Ersam, T.; Nuryastuti, T.;
Santoso, M. Synthesis and anti-tuberculosis activity of trisindolines AIP Conference Proceeding 2018, 2049, 020088.
5. Wardani, E. A.; Fadlan, A.; Santoso, M. Synthesis of 2-ethoxy-1-((3-methyl-2-buten-1-yl)oxy-4-((3-methyl-2-buten-1-yl)oxymethyl))benzene AIP Conference Proceeding 2018, 2049, 020087.
k. Paten :
1. Metoda pembuatan pewangi prenil asetat, prenil propanoat, prenil butirat, prenil isobutirat, prenil 3.3-dimetil butirat, prenil pentanoat, prenil heksanoat (P00201608206) 2. Metoda Pembuatan Perisa/Pewangi 2-Feniletil pentanatiooat, 2-Feniletilisobutanatiooat,
2-Feniletil butanatiooat, 2-Feniletil 3,3-dibutilbutanatiooat (P00201708345)
l. Tugas Akhir :
1. Rinanda Permatasari, 2013, Sintesis dan Toksisitas 6-(5,6-Dimetoksi-1H-indol-3-il)-2,3-dimetoksi-5H-benzo[b]karbazola dan 6-(5,6-Dimetoksi-1-metil-1H-indol-3-il)-2,3-dimetoksi-5-metil-5H-benzo[b]karbazola
2. Trisna Sristia, 2013, Sintesis dan Toksisitas: 3-(5H-benzo[b]karbazol-6-il)-1H-indola, 1-metil-3-(5-metil-5H-benzo[b]karbazol-6-il)-1H-indola, dan
3-(2-hidroksi-5H-benzo[b]karbazol-6-il)-1H-indol-5-ol