Wh."" . . , an LV, medic .. ;o" i. info,od. the .olution th>l it i. mi,cd ,",'jlh may 001 be compalible with 'he "",dic.,;oo. In addi,ion, ,be [,V. line th>l ;Hhosen to admin;"., 'he mediCalioo moy infu .. > ooc""d medic .. ;o" 'hot i. ir>romp>tible
",job ,be firs' medication. In the", ; .. tonce •. iocomp>.tibilily may c •• ", .., .... 1 different ad, ... "n".
n.e
eff",," of the "",dicotion may be ",onger (i.e ..pot.nti.,~), the eff",,\> of til< "",dical;"" ""'Y be we.ker (i.e .. ollonuol«l), or the dfecu of tbe medic.,;o" may be nil (i.e .. in.cti.at<d), In >Orne in".""" •.
mi'ing > medication with .n iocoml"'tible solu,ion 0< "'jlh another iocompatible medication m.y cou"" a chemic.1 ""."tion th>t re.ull> in the d" .. lopment of precipitate in the ",Iutioo, When this precipi'ate i. administered intrneno"'ly.
it can ".u", .. nott. irritatioo (i,e .. phlebiti.) .00 emboli (:lee Ch'p«r 6 for a fu"her discu"ion of phlebi'i' and emboli foem.tioo .00 their ""p,,<"i, ..
tr<>"nen").
(lasses of I.V. Pharmacologic Agents,
Methods of Delivery, and Incompatibilities
LIil. 1here or" a multitude of medi".tioo. that !TIlly he admini.te",d intr.vcnOll.ly.
It i. "'" poosible for .ny dinician to ... iz.e each and ,,',ory pos.ible LV . .... dinti"" that might he prescribed fOf .ny ~i,"n p.tient. il> rec<>mmended .... thod of I, y, del ive ry .• 00 its .tte 00 >!It ",Iu, ion .00 medication i nrompati bil itie •.
However. it i. po .. ible to identify ~e"."tI d •• ..,. of drugs .00 the LV.
admini .... ation guideline> fo.- protOl)'pe drug> in each of the .. d •• ..,., Protot)]1<
drugs ore drug. that belong to a cen.in d ... of drug> and h .. " eff«ts that ....
"'rr"",n"'i,,, of the OIber drug. in the d ... , Fr"'lLl<ntly, protOlype drug. are tbe fi .... drug m.tloted in • gi, .. n drug 01 .... but 001 .h.,.y •. T.ble 11_1 li,,«ommon d ... of drug. that are administered int",,,,,,,,,,.ly, tbei, "'.pecti,·~ protOlype drug>, tbeir re=m .... nded method. fC4" I, y, admini"""ioo, .00 tbeir ",Iutioo .00 drug incompatibili,ie.,
CHAPTER 11 Intravenous PharmacoLogic
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