KESIMPULAN DAN SARAN
5.1. Kesimpulan
Hasil profil skor Nugent berdasarkan pewarnaan Gram pada penederita vaginosis bakterial :
1. Total skor Nugent berdasarkan pewarnaan Gram untuk skor 7-10 (vaginosis bakterial) adalah 100%.
2. Distribusi frekuensi terbesar morfotipe bakteri Gram positif besar
(Lactobacillus) berdasarkan pewarnaan Gram adalah 51,61% untuk skor 4, dan distribusi frekuensi terkecil adalah 1,61% untuk skor 0
3. Distribusi frekuensi terbesar morfotipe bakteri batang Gram negatif kecil dan variabel (Gardnerella dan anerob) berdasarkan pewarnaan Gram adalah 79,0% untuk skor 4, dan distribusi frekuensi terkecil adalah 2% untuk skor 1.
4. Distribusi frekuensi terbesar morfotipe bakteri batang bengkok Gram negatif/ batang Gram variabel (Mobilluncus) berdasarkan pewarnaan Gram adalah 49,99% untuk skor 1, dan distribusi frekuensi terkecil adalah 4,8%, untuk skor 0.
5.2. Saran
Penelitian ini dapat dilanjutkan untuk mendapatkan hasil yang lebih baik, dengan jumlah sampel lebih besar.
DAFTAR PUSTAKA
1. Maskur Z, Makalew HL. VB. Dalam : Daili SF, Makes WIB, Zubier F, Judanarso J, editor. Infeksi menular seksual. Edisi ke-3, cetakan ke-2. Jakarta : Balai penerbit FK UI, 2007; 116-21.
2. Murtiastutik D. VB. Dalam : Barakbah J, Lumintang H, Martodihardjo S, editor. Buku ajar infeksi menular seksual. Surabaya : Airlangga university press, 2008; 73-83.
3. Turovskiy Y, Noll KS, Chikindas M L. The aetiology of bacterial vaginosis.
Journal of Applied Microbiology 2011; 110 : 1105-28
4. Hilier S, Marrazo J, Holmes KK. Bacterial vaginosis. Dalam : Holmes KK, Mardh PA dkk, editor. Sexually transmitted disease. Edisi ke-4. New York : McGraw Hill Inc, 2008; 737-68.
5. Spiegel CA, Amsel R, Holmes KK. Diagnosis of Bacterial Vaginosis by Direct Gram Stain of Vaginal fluid. Journal of Clinical Microbiology 1983; 181 :170-7.
6. Modak T, Arora P, Agnes C, Ray R, Goswami S, Ghosh P, Das N K. Diagnosis of bacterial vaginosis in cases of abnormal vaginal discharge : comparison of clinical and microbiological criteria : J Infect Dev Ctries
2011; 5(5) : 353-60
7. Mehndinejad M, Khorsravi A D, Yazdizadeh H, Afshari P. Bacteriological study of vaginal discharge of pregnant women using Gram stain smar and culture : AfricanJournal of Microbiology Research 2011; 5 : 1994-8
8. B Deborah, Nelson, Macones G : Bacterial vaginosis in pregnancy :Current Findings and Future Directions : epidemiol Rev 2002; 24 : 102-8.
9. Morris M, Nicoll A, Simms I, Wilson J, Catchpole M. Bacterial vaginosis : a public health review : British Journal of Obstetrics and Gynaecology
2001; 108 : 439-50
10. Krisnadi SR. Efek pengobatan klindamisin terhadap kejadian bayi berat badan lahir rendah pada wanita dengan vaginosis bakterial, kolonosasi streptokokus Grup B dan infeksi oleh Chlamidia trachomatis. Disertasi Universitas Padjadjaran, Bandung 2000.
11. Wedagama IGNM, Suwiyoga K. Resiko partus prematurus iminens pada kehamilan dengan vaginosis bakterial. Tesis. Lab/SMF Obstetri dan Ginekologi Fakultas Kedokteran Universitas Kedokteran Universitas Udayana/Rumah Sakit Sanglah, Denpasar, 2000.
12. Effendi IH, Vaginosis bakterial pada ibu hamil di RSU dr. Pirngadi Medan. Tesis bagian Obstetri dan Ginekologi Fakultas Kedokteran Universitas Sumatera Utara, Medan 2004.
13. Sulistyowati SA, Tejo BA, Kusumawardani A, dkk. Prevalensi VB di Poliklinik Kulit dan Kelamin RSUD Moewardi Surakarta periode Januari- Desember 2011. Buku Makalah Lengkap I PIT XII PERDOSKI. Solo 2012; 302-11.
14. Holts E, Wathne B, Hovelius B, Mardh P A. Bacterial Vaginosis : Microbiological and Clinical Findings : Eur J. Clin Microbiol, Oct 1987; 536-41.
15. Spiegel CA. Bacterial vaginosis. Clinical microbiology review, Oct 1991; 485-502.
16. Livengood CH. Bacterial vaginosis : An Overview for 2009. Review in Obstetrics and Gynecology, 2009; 2(1) : 29-37.
17. Begum M, Alam N, rahman K M. Role of nycoplasma hominis in Bacterial Vaginosis. Bangladesh J Med Microbiol 2008; 02 (01) : 18-21.
18. Hay P E. Bacterial vaginosis. Journal of pediatrics, obstetrics and gynaecology, Sep/Oct 2002; 36-40.
19. Chaijareenont K, Sirimai K, Boriboonhirunsarn D, Kiriwat O. Accuracy of Nugent’s Score and Each Amsel’s Criteria in the Diagnosis of Bacterial vaginosis. J Med Assoc Thai, 2004; 87(11) : 1270-3.
20. Ayenalem S, Yusuf L, Ashenafi M. Lactid Acid Bacterial Vaginosis among Outpatients in Addis Ababa : Ethiop J Health Dev 2010; 24(3) :198-204. 21. Katherine A. Fethers, Christopher K. Fairley, Jane S. Hocking,Lyle C.
Gurrin, and Catriona S. Bradshaw. Sexual Risk Factors and Bacterial Vaginosis : A Systematic Review and Meta-Analysis. Clinical Infectious Disease 2008; 47: 1426-35.
22. Evelyne Alesna, Mercy Pascual-Viduya dkk. Multiple Sexual partner : Risk Factor for Bacterial Vaginosis. J Microbiol Infect Dis 1996; 25(1) :1-3 23. Ison CA, Hay PE. Bacterial vaginosis : A diagnostic approach. Genitourin
Med 1992; 68 : 134-8.
24. Morris M C, Rogers P A, Kinghorn GR : Is bacterial vaginosis a sexually transmitted infections : Sex Transm Inf 2001; 77 : 63-8
25. Verstraelen H, Vershelst R, Vaneechoutte M, Temmerman M. The epidemiology of bacterial vaginosis in relation to sexual behaviour : BMC infectious disease 2010; 10 : 81
26. Posner S F, Kerimova J, Aliyeva F, Duerr A : Strategies for diagnosis of bacterial vaginosis in resource-poor setting : Int Journal of STD & AIDS
2005; 16: 52-5
27. Neelam S, Sohail I. Rapid Clinical Diagnostic Test for Bacterial vaginosis and its Predictivr Value : International Journal of Pathology 2010; 8(2) : 50-2
28. Hellberg D, Nilsson S, Mardh P A. The diagnosis of bacterial vaginosis and vaginal flora change : Arch Gynecol Obstet 2001; 265: 11-5.
29. Sexually Transmitted Disease. Treatment Guidlines 2010. Diunduh dari
tanggal 20 April 2015.
30. Menard J P. Antibacterial treatment of bacterial vaginosis : current and emerging therapies : International Journal of Woman Health 2011; 3 : 295- 305.
31. Brotman R M, Klebanoff M A, Nansel T R, Yu K F, Andrews W W, Zhang J, dkk. Bacterial vaginosis Assese by Gram Stain and Diminished Colonization Resistance to incident Gonococal, Chlamydial, and Trichomonal Genital : The Journal of Infectious Disease 2010; 202 (12) : 1907-15.
32. Sumati A. H, Saritha N K. Bacterial vaginosis with special refrence to anaerobs : Indian Journal of Pathology andMicrobiology 2009; 52(1) : 56- 8.
33. Sobel J. D. Bacterial vaginosis : Annu Rev Med 2000; 51 ; 349-56.
34. Taha T E, Hoover D R, Dallabetta G A, Kumwenda N I, Mtimavalye L A R, Yang L P, dkk. Bacterial vaginosis and disturbance of vaginal flora association with increased asquisition of HIV : AIDS 1998; 12 : 1699-1706. 35. Gallo M F, Warner L, King C C, Sobel K J, Klein R S, Uvin S C,dkk.
Association between Semen Exposure and Incident Bacterial Vaginosis :
Infectious Disease in Obstetri and Gynaecology 2011; 1-10
36. Misic M, Randelovic G, Kocic B, Antic S dkk. Complication associated with bacterial vaginosis : Acta Fac Med 2005; 22 (4) : 161-5
37. Falaga M E, Betsi G I, Athanasiou S. Probiotics for the treatment of women with bacterial vaginosis : the european society of clinical microbiolgy and infectious disease 2007; 13 : 657-64.
38. Liahi J M, Rai R, Ison C, dkk. Association of bacterial vaginosis with history of second trismester miscarriage : Human Reproduction 1996; 11 : 1575-8.
39. Yudin M H, Money D M. Screening and Management of Bacterial Vaginosis in Prenancy : Journal of the Obsteri and Gynaecologist of Canada 2008; 211 : 702-8.
40. Thoma M E, Gray R H, Kiwanuka N, Wang M C, dkk. The natural history of bacterial vaginosis (BV) diagnosed by Gram stain among women in Rakai, Uganda : Sex Trans Dis 2011; 38(11) : 1040-5.
41. Novel S S, Wulandari A P, Safitri R. Pewarnaan Gram. Dalam : Novel S S, editor. Praktikum Mikrobiologi Dasar. Jakarta: Trans Info Media ; 2010. 69- 70.
42. Pelczar, Chan. Pewarnaan Gram. Dalam: Pelczar, editor. Mikrobiologi. Jakarta : Mikrobiologi Universitas Indonesia ; 1986.
43. Anggarwati D, Binarso A, Soejoenoes A. Studi prevalensi dan keberhasilan terapi vaginosis bakterial pada ibu hamil. Bagian Obstetri dan Ginekologi FK Diponegoro/RSUP dr. Kariadi, Semarang. KOGI XII Yaogyakarta, 2003.
44. Nuswil B, Kurdi AS, Zaimursyaf A, Marwansya FM, Theodorus, Husni M. Perbandingan kejadian vaginosis bakterial pada partus preterm dan partus normal. Bagian Obstetri dan Ginekologi FK Sriwijaya, Palembang. KOGI XII Yaogyakarta, 2003.
45. Newton ER, Piper JM, Shain RN et al. Predictors of the vaginal microflora. Am J Obstet Gynecol 2001 ; 184:845-55.
46. Ness R B, Kip K E, Soper D E, et al. Variability of bacterial vaginosis over 6-12 months interval. Sex transm dis. 2006;33 : 381-5.
