BAB V KESIMPULAN DAN SARAN
5.2 Saran
1. Dari penelitian ini didapat ekspresi L-Selectin yang lebih tinggi pada jaringan endometriosis sehingga diharapkan hasil penelitian ini dapat dijadikan data dasar untuk penelitian lebih lanjut dalam hal pengembangan strategi pengobatan tentang penggunaan obat- obatan yang dapat menghambat kerja dari L-Selectin seperti penggunaan L-Selectin inhibitor sehingga diharapkan dengan pemberian obat tersebut proses inflamasi yang terjadi akan berkurang.
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Lampiran Hasil Analisa Statistik
Tabel 4.1. Distribusi Responden Berdasarkan Usia
Klp_Umur * Objek Crosstabulation
Objek Total Endometriosis Normal Klp_Umur 18 - 35 Count 17 11 28 % within Objek 56,7% 36,7% 46,7% >35 Count 13 19 32 % within Objek 43,3% 63,3% 53,3% Total Count 30 30 60 % within Objek 100,0% 100,0% 100,0%
Tabel 4.2. Distribusi Responden Berdasarkan Stadium Endometriosis
Stad. Endometriosis * Objek Crosstabulation
Objek
Total Endometriosis
Stad. Endometriosis Ringan Count 5 5
% within Objek 16,7% 16,7% Sedang Count 12 12 % within Objek 40,0% 40,0% Berat Count 13 13 % within Objek 43,3% 43,3% Total Count 30 30 % within Objek 100,0% 100,0%
Tabulasi Silang Ekspresi L-Selectin observer 1 dan Ekspresi L- Selectin
observer 2
Ekspresi L-Selectin * Ekspresi L-Selectin Crosstabulation
Count
Ekspresi L-Selectin Observer 2
Total +1 +2 +3 Ekspresi L-Selectin Observer 1 +1 6 0 0 6 +2 1 11 0 12 +3 0 3 9 12 Total 7 14 9 30 Symmetric Measures Value Asymp. Std.
Errora Approx. Tb Approx. Sig.
Measure of Agreement Kappa ,794 ,096 6,104 ,000
N of Valid Cases 30
a. Not assuming the null hypothesis.
Tabel 4.3. Perbandingan Ekspresi L-Selectin Pada Jaringan Endometriosis dan Non Endometriosis
Ekspresi L-Selectin * Objek Crosstabulation
Objek
Total
Endometriosis Normal
Ekspresi L-Selectin 0 Count 0 30 30
% within Objek ,0% 100,0% 50,0% 1 Count 6 0 6 % within Objek 20,0% ,0% 10,0% 2 Count 12 0 12 % within Objek 40,0% ,0% 20,0% 3 Count 12 0 12 % within Objek 40,0% ,0% 20,0% Total Count 30 30 60 % within Objek 100,0% 100,0% 100,0% Chi-Square Tests Value Df Asymp. Sig. (2-sided) Exact Sig. (2- sided) Exact Sig.
(1-sided) Point Probability
Pearson Chi- Square
60,000a 3 ,000 ,000
Likelihood Ratio 83,178 3 ,000 ,000
Fisher's Exact Test 71,200 ,000
Linear-by-Linear Association
47,913b 1 ,000 ,000 ,000 ,000
N of Valid Cases 60
a. 2 cells (25,0%) have expected count less than 5. The minimum expected count is 3,00. b. The standardized statistic is -6,922.
Tabel 4.4. Tabel Perbandingan Ekspresi L-selectin Berdasarkan Stadium Endometriosis
Stad. Endometriosis * Ekspresi L-Selectin Crosstabulation
Ekspresi L-Selectin
Total
1 2 3
Stad. Endometriosis Ringan Count 4 1 0 5
% within Stad. Endometriosis 80,0% 20,0% ,0% 100,0% Sedang Count 2 7 3 12 % within Stad. Endometriosis 16,7% 58,3% 25,0% 100,0% Berat Count 0 4 9 13 % within Stad. Endometriosis ,0% 30,8% 69,2% 100,0% Total Count 6 12 12 30 % within Stad. Endometriosis 20,0% 40,0% 40,0% 100,0% Chi-Square Tests Value df Asymp. Sig. (2-sided) Exact Sig. (2-sided) Exact Sig.
(1-sided) Point Probability
Pearson Chi-Square 18,904a 4 ,001 ,000
Likelihood Ratio 19,212 4 ,001 ,001
Fisher's Exact Test 14,908 ,001
Linear-by-Linear Association
14,139b 1 ,000 ,000 ,000 ,000
N of Valid Cases 30
a. 7 cells (77,8%) have expected count less than 5. The minimum expected count is 1,00. b. The standardized statistic is 3,760.