BAB VII SIMPULAN DAN SARAN
7.2 Saran
Saran dari penelitian ini adalah:
1. Perlu dilakukan penelitian lebih lanjut untuk mengkaji efek dari ekstrak teh hijau dan ekstrak teh putih dengan menggunakan beberapa dosis yang berbeda.
2. Perlu dilakukan penelitian terhadap efek dari ekstrak teh hijau dan ekstrak teh putih dalam perbaikan profil lipid dengan durasi perlakuan yang lebih panjang.
3. Perlu dilakukan penelitian lebih lanjut untuk mengetahui dosis toksik dari teh hijau dan teh putih.
4. Perlu dilakukan penelitian lebih lanjut dengan menggunakan sampel teh hijau dan teh putih dari beberapa daerah yang berbeda.
5. Perlu dilakukan uji klinis terhadap efek dari ekstrak teh hijau dan ekstrak teh putih pada manusia.
6. Perlu dilakukan uji molekuler kandungan teh hijau dan teh putih terhadap perbaikan profil lipid.
DAFTAR PUSTAKA
Abolfathi, A. A., Mohajeri, D., Rezaie, A., Nazeri, M. 2012. Protective Effects of Green Tea Extract Against Hepatic Injury in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. [Cited September 2015].
Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432555/.
ACC/AHA. 2013. Guideline on Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. [Cited Oktober 2015]. Available at: http://content.onlinejacc.org/on11/13/2013.
Adam, J. M. F. 2011. “Peran HDL-Kolesterol dalam Mencegah Penyakit Arteri Koroner pada Penderita Diabetes”. Artikel Ilmu Penyakit Dalam Universitas Hasanudin Makasar, 1 Februari. [Cited Oktober 2015]. Available from: http://dokternetworkangk97.blogspot.co.id/2011/02/peran-hdl-kolesterol-dalam-mencegah.html.
Alamsyah, A. 2006. Taklukan Penyakit dengan Teh Hijau. Jakarta: Agro Medika Pustaka. Hal. 34-36, 46-58, 59-60.
Alcazar, A., Ballesteros, O., Jurado, J. M., Pablos, F., Martin, M. J., Vilches, J. L., Navalon, A. 2007. Differentiation of Green, White, Black, Oolong, and Pu-erh Teas According to Their Free Amino Acids Content. Journal of Agricultural and Food Chemistry 55(15): p. 5960-5. [Cited November 2015]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17595106.
Almajano, M. P., Carbo, R., Jimenez, J. A. L., Gordon, M. H. 2008. Antioxidant and Antimicrobial activities of tea infusions. Food Chemical 108 (1): p. 55-63.
Almajano, M. P., Villa, I., Gines, S. 2011. Neuroprotective effects of white tea against oxidative stress-induced toxicty in striatal cells. Neurotoxicity Research, v. 20, p. 372-8.
Available from: http://dx.doi.org/10.1038/sj.bjp.0706255.
American Association of Clinical Endocrinologists (AACE). 2012. Guidelines for Management of Dyslipidemia and Prevention of Atheroslerosis. Endocrine Practice 18(Suppl. 1): p. 1-78.
Anwar, T. B. 2004. “Disiplidemia Sebagai Faktor Risiko Penyakit Jantung Koroner” (e-USU Repository). Sumatera: Universitas Sumatera Utara. [Cited 1 Oktober 2015].
Anonim (a). 2014. Camellia sinensis. [Cited 5 November 2015]. Available at: http://en.wikipedia.org/wiki/Camellia_sinensis.
Anonim (b). 2011. Jenis Teh. [Cited Februari 2016]. Available at: http://kamusmasak.blogspot.co.id/2011/12/jenis-teh.html.
Anonim (c). 2014. Manfaat Teh Putih bagi Kesehatan. [Cited Februari 2016]. Available at: http://www.tokomedica.com/blog/manfaat-teh-putih-bagi-kesehatan.
Anonim (d). 2015. Manfaat Teh Hijau untuk Kesehatan. [Cited Februari 2016]. Available at: http://sehatplan.com/manfaat-teh-hijau-untuk-kesehatan/. Arora, B. P. 2008. Anti-Aging Medicine. Indian Journal of Plastic Surgery
41(Suppl): p. S130–S133.
Auvichayapat, P., Prapochanung, M., Tunkamnerdthai, O., Sripanidkulchai, B., Auvichayapat, N., Thinkhamrop, B., Kunhasur, S., Wongpratoom, S., Sinawat, S., Hongprapas. 2008. Effectiveness of Green Tea on Weight Reduction in Obese Thais: A randomized, controlled trial. Physiology Behaviour, 93(3): p. 486-491.
Babu, P. V., Sabitha, K. E., Shyamaladevi, C. S. 2006. Green Tea Impedes Dyslipidemia, Lipid Peroxidation, Protein Glycation, and Ameliorates Ca2+-ATPase and Na+/K+-ATPase activity in the Heart of Streptozocin-diabetic Rats. Chem. Biol. Interact. 162(2): p. 157-164.
Battacharya, U., Mukhopadhyay, S., Giri, A. K. 2011. Comparative Antimutagenic and Anticancer Activity of Three Fractions of Black Tea Polyphenols Thearubigins. Nutrition and Cancer 63(7): p. 1122-1132. Bays, H. E., Toth, P. P., Penny, M., Kris-Etherton, Abate, N., Aronne, L. J.,
Brown, W. V., Gonzales-Campoy, J. M., Jones, S. R., Kumar, R., La Forge, R., Samuel, V. T. 2013. Obesity, Adiposity, and Dyslipidemia: A Consensus Statement from National Lipid Association.
Butt, M. S., Sultan, M. T. 2009. Levels of Trans Fats in Diets Consumed in Developing Economies. Journal of AOAC International 92(5): p. 1277-1283.
Carvalho, M., Jeronimo, C., Valentao, P., Andrade, P. B., Silva, B. M. 2010. Green Tea: A Promising Anticancer Agent for Renal Cell Carcinoma. Food Chemistry 122(1): p. 49-54.
Cheng, T. O. 2000. Tea is Good for The Heart. Archives of Internal Medicine 160(15): p. 2397.
Chiang, J. Y. 2004. Regulation of Bile Acid Synthesis: Pathways, Nuclear Receptors, and Mechanisms. Journal of Hepatology 40: 539-551.
Dahlia, D. 2014. “Pemberian Ekstrak Teh Putih (Camellia Sinensis) Oral Mencegah Dislipidemia pada Tikus (Rattus Norvegicus) Jantan Galur Wistar yang Diberi Diet Tinggi Lemak” (tesis). Denpasar: Universitas Udayana.
Deka, A., Vita, J. A. 2011. Tea and Cardiovascular Diseases-Review. Pharmacological Research 64: p. 136-145.
Del-Bas, J. M., Fernández-Larrea, J., Blay, M., Ardèvol, A., Salvadó, M. J. 2005. Grape Seed Procyanidins Improve Atherosclerotic Risk Index and Induce Liver CYP7A1 and SHP Expression in Healthy Rats. The Journal of The Federation of American Societies for Experimental Biology 19 (3): 479– 481.
Dias, T. R., Tomas, G., Teixeira, N. F., Alves, M. G., Oliveira, P. F., Silva, B. M. 2013. White Tea (Camellia Sinensis (L.)): Antioxidant Properties and Beneficial Health Effects.
Eckardstein, A. V., Nover, J. R., Assmann, G. 2010. High Density Lipoprotein and Arteriosclerosis. Arterioscler. Thromb. Vasc. Biol. 21: p. 13-27. Fauzi, H. M. N. 2012. Minyak Sawit Mengganggu Kesehatan. [Cited Januari
2016].
Available from: http://idijember.6te.net/minyak_sawit_ganggu_kesehatan.htm. Ferrier, D. R. 2014. Lippincott’s Illustrated Reviews: Biochemistry. 6th. Ed.
Philadelphia: Lippincott Williams and Wilkins.
Forester, S. C., Lambert, J. D. 2011. The Role of Antioksidant Versus Prooxidant Effect of Green Tea Polyphenols in Cancer Prevention. Mol. Nutr. Food Res. 55(6): p. 844-854.
Goldstein, J. L., Brown, M. S. 2009. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: p. 431-438 doi: 10.1161/ATVBAHA.108.179564.
Gordon, P. M. 2003. Hyperlipidemia and Dyslipidemia. In Ehrman JK. Clinical Exercise Physiology. Champaign: Human Kinetics. p. 169-184.
Green, D. J., Jones, H., Thijssen, D., Cables, N. T., Atkinson, G. 2011. Flow-Medicated Dilation and Cardiovascular Event Prediction: Does Nitric Oxide Matter? Hypertension 2011 March 57(3): p. 363 - 9.
Grundy, S. M. 2006. Nutrition in The Management of Disorder of Serum Lipids and Lipoprotein. Modern Nutrition in Health and Disease. 10th. Ed. Baltimore: Lippincott Williams and Wilkins. p. 1076-1094.
Halim, H. 2006. Majalah Kedokteran Damianus. V.01.5, No.3. September 2006. Han, M. K. 2003. Epigallocatechin Gallate, a Consistuent of Green Tea,
Suppresses Cytokine-Induced Pancreatic Beta-Cell Damage. Experimental and Molecular Medicine 35(2): p. 136-139.
Handoko, D. 2007. “Pengaruh Tekanan dan Suhu Pada Kondisi Evaporasi Ekstrak Daun Teh Hijau” (skripsi). Bogor: Institut Pertanian Bogor.
Hardini, D., Yuwanta, T., Supadmo, Zuprizal. 2007. Pengaruh Telur Beromega-3 dan 6 Hasil Olahan terhadap Profil Lipid Darah Tikus Rattus norvegicus L. Normal dan Hiperkolesterolemia. Media Peternakan 30(1): hal. 26-34. Harrison's Principles of Internal Medicine. 2015. Disorders of Lipoprotein
Metabolism. 19th. Ed. (Rader, D. J., Hobs, H. H.). New York: McGraw-Hill. p 2451-3216.
Hatma, R. D. 2011. Lipid Profiles Among Diverse Ethnic Groups in Indonesia. Acta Med Indones. 43(1): p. 4-11.
Hayashi, T., Maruyama, H., Kasai, R., Hattori, K., Takasuga, S., Hazeki, O., Yamasaki, K., Tanaka, T. 2002. Ellagitannins From Lagerstroemia Speciosa as Activators of Glucose Transport in Fat Cells. Planta Med. 68(2):173-5.
Hilal, Y; Engelhardt, U. 2007. Characterisation of White Tea–Comparison to Green and Black Tea. J. Verbr. Lebensm 2(2007): p. 414 – 421.
Hubrecht, R., Kirkwood, J. 2010. The UFAW Handbook of The Care and Management of Laboratory and Other Research Animals. 8th. Ed. Universities Federation for Animal Welfare. p. 311-324.
Illingworth, D. R. 2007. Lipid Lowering Drugs: An Overview of Indications and Optimum Theraupetic Use. Drugs 33: p. 259-79.
Islam, M. 2011. Effects of The Aqueous Extract of White Tea (Camellia Sinesis) in a Streptozotocin-Induced Diabetes Models of Rats. Phytomedicine 19(1): p. 25-31.
Jurevics, H., Hostettler, J., Barrett, C., Morell, P., Toews, A. D. 2000. Diurnal and Dietary-Induced Changes in Cholesterol Synthesis Correlate with Levels of mRNA for HMG-CoA Reductase. Journal of Lipid Research 41: 1048– 1053.
Kao, Y. H., Hiipakka, Liao, S. 2000. Modulation of Obesity by a Green Tea Catechin. Am J Clin Nutr. 72(5): p. 1232-4.
Karlsen, A., Retterstol, L., Laake, P., Paur, I., Kjolsrud-Bohn, S., Sandvik, L., Blomhoff, R. 2007. Anthocyanins Inhibit Nuclear Factor- Kappa Activation In Monocytes and Reduce Plasma Concentrations of Pro- Inflammatory Mediators In Healthy Adults. Journal of Nutrition 137:1951-4
Kersshaw, E.E., Flier, J.S. 2004. Adipose Tissue as an Endocrine Organ. The Journal of Clinical Endocrinology & Metabolism 89(6): p. 2548-2556. Kimura, K., Ozeki, M., Juneja, L. R., Ohira, H. 2007. L-Theanin Reduces
Psychological and Physiological Stress Responses. Biological Psychology 74(1): p. 39-45.
Koolman, J., Roehm, K. H. 2005. Color Atlas of Biochemistry. 2th. Ed. New York: Georg Thieme Verlag. p. 162-164.
Krinke, G. J. 2000. The Laboratory Rat. The Handbook of Experimental Animals. Academic Press. p. 3-56.
Kumar, M. 2012. Protective Effects of Green and White Tea Against Benzo (a) Pyrene Induced Oxidative Stress and DNA Damage in Murine Model. Nutrition and Cancer, v. 64, n.2: p. 300-6.
Available from: http://dx.doi.org/10.1080/01635581.
Kusumawati, D. 2004. Bersahabat dengan Hewan Coba. Yogyakarta: Gadjah Mada University Press.
Lee, R. G., Shah, R., Sawyer, J. K., Hamilton, R. L., Parks, J. S. 2005. ACAT2 Contributes Cholesteryl Esters to Newly Secreted VLDL, Whereas LCAT Adds Cholesteryl Ester to LDL in Mice. J Lipid Res 46: 1205–1212. Lichtenstein, A. H., Jones, P. J. H. 2006. Lipids Absorption and Tranport. In
Present Knowledge in Nutrition. 8th. Ed. Washington DC: ILSI Press. p. 93-103.
Liu Di, Jia-Ying, X., Yang, J. 2012. Effects of Puer Tea Aqueous Extracts and Green Tea Polyphenols on The Expression of Longevity Related Gene CETP. Chinese Journal of Gerontology 2012(02).
Liu, F., Kim , J. K., Li, Y. K.,Liu, X., Li., J., Chen, X. 2001. An Extract of Lagerstroemia speciosa L. Has Insulin-Like Glucose Uptake–Stimulatory and Adipocyte Differentiation–Inhibitory Activities in 3T3-L1 Cells1. J Nutr., Sep;131(9):2242-7.
Liu, K., Liang, X., Kuang, W. 2011. Tea Consumption Maybe an Effective Active Treatment for Adult Attention Deficit Hyperactivity Disorder (ADHD). Elsevier Medical Hypotheses, v. 76: p. 461-463.
Lopez, V., Calvo, M. I. 2011. White tea (Camellia Sinensis Kuntze) Exerts Neuroprotection Against Hydrogen Peroxide-Induced Toxicity in PC12 Cells. Plant Food for Human Nutrition, v. 66, n. 1: p. 22-6.
Available from: http://dx.doi.org/10.1007/s11130-010-0203-3.
Mackenzie, T., Leary, L., Brooks, W. B. 2007. The Effect of an Extract of Green Tea on Glucose Control in Adult with Type 2 Diabetes Mellitus: Double-Blind Randomized Study. Metabolism 56(10): p. 1340-1344.
Mahan, K., Stump, S. E., Raymond, J. 2012. Krause’s Food and The Nutrition Care Process. 13th. Ed. USA: Elsevier.
Mahley, R. W., Weisgraber, K. H., Farese, R. V. 2003. Disorder of Lipid Metabolism. In William Textbook of Endocrinology. 10th. Ed. Philadelphia: Saunders. p. 1642-1680.
Margareth, M. C. 2014. “Pemberian Hormon Melatonin Memperbaiki Profil Lipid Darah Tikus Putih Jantan (Albino Rat) Dislipidemia tetapi Tidak Lebih Baik dari Statin” (tesis). Denpasar: Universitas Udayana.
Maron, D. J., Lu, G. P., Cai, N. S., Wu, Z. G., Li, Y. H. 2003. Cholesterol-Lowering Effect of a Theaflavin-Enriched Green Tea Extract: a Randomized Controlled Trial. Archives of Internal Medicine 163(12): p. 1448.
Mayes, P. A., Botham, K. M. 2003. Lipid Transport and Storage. Harper's Illustrated Biochemistry. 26th. Ed. USA: McGraw-Hill. p. 205-18.
Moderno, P., Carvalho, M., Silva, B. 2009. Recent Patents on Camellia Sinesis: Source of Health Promoting Compounds. Recent Patents on Food, Nutrition, and Agriculture 1(13): p. 182.
Murray, R. , Bender, D., Botham, K. M., Kennelly, P. J., Rodwell, V., Weil, P. A. 2012. Harper’s Illustrated Biochemistry. 29th. Ed. New York: Lange. Murray, R., Granner, K. D., Mayes, A. P., Rodwell, V. 2003. Harper’s
Biochemistry. 26 th. Ed. New York: Appleton & Lange Medical Books. p.160-191.
Nagao, T., Hase, Tokimitsu. 2007. A Green Tea Extract High in Catechins Reduces Body Fat and Cardiovascular Risks in Humans. Obesity (Silver Spring) 15(6): p. 1473-83.
National Cholesterol Educational Program. 2015. [Cited September 2015]. Available at: http://www.nhlbi.nih.gov/files/docs/guidelines/atglance.pdf. Ngatijan. 2006. Metode Laboratorium dan Toksikologi; Metode Uji Toksisitas.
Yogyakarta: Bagian Farmakologi dan Toksikologi FK UGM. Hal: 86. Nichols, J. 2003. The Laboratory Rat. Florida Atlantic University. [Cited: 10
Oktober 2015].
Available from: http://www.fau.edu/research/ovs/VetData/rat.php/. Nugroho. 2008. Metabolisme Lipid. [Cited 2 Oktober 2015]. Available from:
http://static.schoolrack.com/files/14204/34773/5.
Nugroho. 2009. Respirasi Seluler. [Cited Oktober 2015]. Available from: http://biodas.files.wordpress.com/2007/09/04-respirasi-sel.ppt.
Pangkahila, W. 2007. Anti Aging Medicine: Memperlambat Penuaan, Meningkatkan Kualitas Hidup. Cetakan ke-1. Jakarta: Penerbit Buku Kompas. Hal: 8-17.
Pangkahila, W. 2011. Anti Aging Medicine : Tetap Muda dan Sehat. Cetakan ke-1. Jakarta: Penerbit Buku Kompas. Hal: 1-3, 9-10, 33-6ke-1.
Perdomo, G., Henry-Dong, H. 2009. Apolipoprotein D in Lipid Metabolism and its Functional Implication in Atherosclerosis and Aging. Aging (Milano) 1: p. 17–27.
Pereira, V. P., Knor, F. J., Vellosa, J. C. R., Beltrame, F. L. 2014. Determination of Phenolic Compounds and Antioxidant Activity of Green, Black and White Teas of Camellia sinensis (L.) Kuntze, Theaceae. Rev. Bras. PI. Med., Campinas., v.16, n.3, p.490-498.
Perez-Jimenez, A. 2011. The Effect of Dietary Methionine and White Tea on Oxidative Status of Gilthead Sea Bream (Sparus aurata). British Journal of Nutrition. p. 1-8.
Perez-Jimenez, A. 2012. The Effect of Hypoxia on Intermedietary Metabolism and Oxidative Status in Gilthead Sea Bream (Sparus aurata) Fed on Diets Supplemented with Methionine and White Tea. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, v. 155, n. 3: p. 506-16.
Pocock, S. J. 2008. “Clinical Trials; A Practical Approach”. New York: A Willey Medical Publication.
Qin, Y., Xia, M., Ma, J., Hao, Y. T., Liu, J., Mou, H. Y., Cao, L., Ling, W. H. 2009. Anthocyanin Supplementation Improves Serum LDL- and HDL Cholesterol Concentrations Associated with The Inhibition of Cholesteryl Ester Transfer Protein in Dyslipidemic Subject. The American Journal of Clinical Nutrition, 90(3):485-492.
Rader, D. J., Hobbs, H. H. 2005. In Harrison’s Principles of Internal Medicine. 16th. Ed. New York: McGraw-Hill. p. 2286-2298.
Rain, T. M., Agarwal, S., Maki, K. C. 2011. Antiobesity Effect of Green Tea Catechins: a Mechanistic Review. J. Nurt. Biochem., 22(1): p. 1-7.
Resdiyanto, W. 2015. Manfaat Minum Teh Hijau. [Cited Februari 2016]. Available from: http://info-kesehatan-99.blogspot.co.id/2015/06/apa-itu-teh-hijau-manfaatnya-bagi-tubuh.html.
Rohdiana, D. 2009. Teh ini Menyehatkan Telaah Ilmiah Populer. Bandung: Penerbit Alfabeta. hal. 70-74, 9-17, 41-49.
Roy, H., Lundy, S., Kalicki, B. 2007. Green Tea: Metabolic Influences. Pennington Nutrition Series. (9).
Rusak, G., Komes, D., Likic, S., Horzic, D., Kovac, M. 2008. Phenolic Content and Antioxidative Capacity of Green and White Tea Extracts Depending on Extraction Conditions and The Solvent Used. J. Food Chemistry., 110 (2008): 852-858.
Santoso, H., Ismail, A. 2009. Memahami Krisis Lanjut Usia. Cetakan Pertama. Jakarta: BPK Gunung Mulia. Hal: 1-7.
Seeram, N. P., Henning, S. M., Yantao, N., Lee, R., Scheuller, H. S., Heber, D. 2006. Catechin and Caffeine Content of Green Tea Dietary Supplements and Correlation with Antioxidant Capacity. J. Agric. Food Chem., 54(5): p. 1599-1603.
Shi, Y., Guo, R., Wang, X., Yuang, D., Zhang, S., Wang, J., Yang, X., Wang, C. 2014. The Regulation of Alfalfa Saponin Extract on Key Genes Involved in Hepatic Cholesterol Metabolism in Hyperlipidemic Rats. Claret M, ed. PLoS ONE. 9(2):e88282.
Shipp, J., Abdel-Aal. 2010. Food Applications and Physiological Effects of Anthocyanins as Functional Food Ingredients. In: The Open Food Science Journal, 4: p. 7-22.
Shulman, G. I. 2000. Cellular Mechanisms of Insulin Resistence. J. Clin. Invest. p. 106, 171.
Smith, J. B., Mangkoewidjojo, S. 1988. Pemeliharaan, Pembiakan dan Penggunaan Hewan Percobaan di Daerah Tropis. Jakarta: Penerbit Universitas Indonesia (UI Press). hal: 30 – 32 , 43-44, 54,57.
Sujayanto. G., 2008. Khasiat Teh untuk Kesehatan dan Kecantikan. Flona Serial Oktober (I). Jakarta: ITB. Hal. 34-38.
Sulaksono, S. 2013. Khasiat Manfaat Rutin Minum Teh Hijau Setiap Hari. CaraKhasiatManfaat-Kesehatan dan Gaya Hidup Alami. [Cited Februari 2016].
Available from:
http://www.carakhasiatmanfaat.com/artikel/khasiat-manfaat-rutin-minum-teh-hijau-setiap-hari.html.
Teixeira, N. F., Gonçalves, L., Lages, P. C., Jascolka, T. L., Aguilar, E.C., Soares, F. L. P., Pereira, S. S., Beltrao, N. R. M., Matoso, R., Nascimento, A., Castilho, R. O., Leite, J. I. A. 2012. White tea (Camellia sinensis) Extract Reduces Oxidative Stress and Triacylglycerols in Obese Mice. Ciência e Tecnologia de Alimentos, vol.32, no.4 Campinas.
Thring, T. S., Hili, P., Naughton, D. P. 2009. Anti-Collagenase, Anti-Elastase and Anti-Oxidant Activities of Extract from 21 Plants. BMC Complementary and Alternative Medicine, v. 9, n. 27.
Thring, T. S., Hili, P., Naughton, D. P. 2011. Antioxidant and Potential Anti-Inflammatory Activity of Extracts and Formulations of White Tea, Rose and Witch Hazel on Primary Human Dermal Fibroblast Cells. Journal Inflammation, v.8, n. 1: p. 27.
Available from: http://dx.doi.org/10.1186/1476-9255-8-27.
Towaha, J. 2013. Kandungan Senyawa Kimia pada Tanaman Teh (Camellia Sinensis). Warta Penelitian dan Pengembangan Tanaman Industri Desember 2013, Vol. 19 No. 3: hal. 12-16.
Unachukwu, U. J., Ahmed, S., Kavalier, A., Lyles, J. T., Kennelly, E. J. 2010. White and Green Teas (Camellia sinensis var. Sinensis): variation in phenolic, methylxanthine, and antioxidant profiles. J. Food Sci., 75(6):541-8.
Wang, R. 2008. Protective Versus Promotional Effects of White Tea and Caffeine on PhIP-Induced Tumorigenesis and Beta-catenin Expression in the Rat. Carcinogenesis, v.29, n. 4: p. 834-9.
Weber, J. M., Ruzidana-Umunyana, A., Imbeault, L., Sircars, S. 2003. Inhibition of Adenovirus Infection and Adenain by Green Tea Cathechins. Antiviral Research 58(2): p. 167-173.
Wibowo. 2003. The Concepts of Anti Aging and How to Make Without Disorder. Jakarta: FKUI. p. 11-17.
Xiao, J., Chen, X., Zhang, L., Talbot, S. G., Li, G. C., Xu, M. 2008. Investigation of the Mechanism of Enhanced Effect of EGCG on Huperzine A’s Inhibition of Acetylcholinesterase Activity in Rats by a Multispectroscopic Method. J. Agric. Food Chem., 56(3): p. 910-915.
Yang, C. S., Wang. 2011. Mechanistic Issues Concerning Cancer Prevention by Tea Catechins. Mol. Nurt. Food Res., 55(6): p. 819-831.
Yusi. 2015. Teh Putih. [Cited Februari 2016]. Available from: http://pecintakopinteh.blogspot.co.id/2015/06/teh-putih.html.
Zhu, W. L., Shi, H. S., Wei, Y. M., Wang, S. J., Sun C. Y. 2011. Green Tea Polyphenols Produces Antidepressant-like Effects in Adult Mice. Pharmacological Research. [Cited Oktober 2015]. Available from: http://www.nhlbi.nih.gov/health/dci/Diseases/Hbc/HBC_WhatIs.html.
LAMPIRAN
Lampiran 4. Tabel Sisa Pakan dan Berat Badan No Kode sampel BB Awal BB Akhir
SISA PAKAN Hari ke
1 2 3 4 5 6 7 8 9 10 11 12 13 14 1 1TP 207 214 8 9 10 8 6 7 8 11 7 7 8 7 8 9 2 2TP 215 219 6 7 8 7 9 8 7 6 7 10 6 6 11 8 3 3TP 211 216 9 7 8 6 6 5 7 6 7 8 7 9 10 6 4 4TP 206 214 7 8 9 7 12 6 7 8 7 8 7 8 8 7 5 5TP 214 219 9 7 8 9 6 7 8 6 7 8 7 8 8 7 6 6TP 213 219 8 9 8 9 10 11 6 7 5 6 7 8 6 7 7 7TP 215 221 9 7 8 9 8 7 8 11 8 9 5 6 7 6 8 8TP 210 217 8 9 7 8 6 7 5 6 7 6 7 6 7 8 9 9TP 206 212 7 8 6 7 9 8 7 8 6 7 9 8 10 6 10 10TP 217 222 7 6 8 9 12 7 8 11 12 7 8 6 9 8 11 11TH 210 215 8 8 8 6 8 4 7 6 8 9 7 8 9 7 12 12TH 201 207 6 8 9 7 11 6 9 8 10 7 9 11 9 7 13 13TH 205 211 7 8 6 11 9 7 11 6 8 9 7 8 9 8 14 14TH 212 219 8 7 7 9 8 9 9 7 8 6 9 7 8 6 15 15TH 200 207 9 7 6 7 8 7 7 8 6 8 8 7 8 5 16 16TH 203 208 8 7 9 8 7 9 6 7 8 9 6 6 7 8 17 17TH 215 221 5 7 6 8 9 7 9 11 9 7 10 9 6 6 18 18TH 216 224 6 7 5 8 7 12 9 8 8 9 9 7 6 8 19 19TH 219 226 5 7 6 8 11 8 6 7 8 9 7 8 6 7 20 20TH 206 212 6 7 8 7 6 7 8 9 8 7 6 8 9 9
Lampiran 5. Analisis Statistik ANALISIS DESKRIPTIF Data Pretest Report Kelompok Kolesterol TG HDL LDL Teh Putih N 10 10 10 10 Mean 217.9990 160.5110 23.1680 94.0000 Std. Deviation 3.42968 3.85165 .65421 3.63391 Minimum 211.38 154.44 22.19 89.89 Maximum 222.17 165.42 24.50 99.07 Teh Hijau N 10 10 10 10 Mean 222.7000 159.4350 22.8190 92.0750 Std. Deviation 5.78948 4.36729 1.28960 3.80149 Minimum 213.27 152.18 21.84 85.87 Maximum 230.52 164.92 26.34 97.03 Total N 20 20 20 20 Mean 220.3495 159.9730 22.9935 93.0375 Std. Deviation 5.22154 4.04556 1.01122 3.75176 Minimum 211.38 152.18 21.84 85.87 Maximum 230.52 165.42 26.34 99.07
Data Posttest Report Kelompok Kolesterol TG HDL LDL Teh Putih N 10 10 10 10 Mean 111.5190 86.3110 59.9150 35.2590 Std. Deviation 3.55796 3.24942 .80739 1.78629 Minimum 106.74 80.92 58.78 32.37 Maximum 119.20 89.71 61.02 38.78 Teh Hijau N 10 10 10 10 Mean 98.6390 77.2480 67.9300 26.5160 Std. Deviation 3.47947 4.34300 1.92683 1.88981 Minimum 90.82 70.32 63.48 23.21 Maximum 102.94 81.77 71.02 29.62 Total N 20 20 20 20 Mean 105.0790 81.7795 63.9225 30.8875 Std. Deviation 7.44228 5.96248 4.35577 4.82897 Minimum 90.82 70.32 58.78 23.21 Maximum 119.20 89.71 71.02 38.78
UJI NORMALITAS DATA
Data Pretest
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk
Statistic df Sig. Statistic df Sig.
Kolesterol Teh Putih .190 10 .200* .927 10 .415
Teh Hijau .152 10 .200* .950 10 .674 TG Teh Putih .136 10 .200* .945 10 .615 Teh Hijau .138 10 .200* .945 10 .612 HDL Teh Putih .162 10 .200* .961 10 .801 Teh Hijau .360 10 .001 .638 10 .879 LDL Teh Putih .186 10 .200* .872 10 .105 Teh Hijau .170 10 .200* .942 10 .579
a. Lilliefors Significance Correction
Data Posttest
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk
Statistic df Sig. Statistic df Sig.
Kolesterol Teh Putih .157 10 .200* .935 10 .502
Teh Hijau .207 10 .200* .906 10 .257 TG Teh Putih .235 10 .126 .854 10 .065 Teh Hijau .307 10 .088 .813 10 .071 HDL Teh Putih .166 10 .200* .932 10 .465 Teh Hijau .231 10 .138 .888 10 .160 LDL Teh Putih .181 10 .200* .973 10 .915 Teh Hijau .159 10 .200* .966 10 .853
a. Lilliefors Significance Correction
ANALISIS KOMPARASI
Data Pretest
Independent Samples Test
Levene's Test for Equality of Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper Kolesterol Equal variances
assumed 3.143 .093 -2.209 18 .440 -4.70100 2.12793 -9.17161 -.23039 Equal variances not assumed -2.209 14.624 .444 -4.70100 2.12793 -9.24675 -.15525 TG Equal variances assumed .067 .799 .584 18 .566 1.07600 1.84142 -2.79269 4.94469 Equal variances not assumed .584 17.723 .566 1.07600 1.84142 -2.79703 4.94903 HDL Equal variances assumed .485 .495 .763 18 .455 .34900 .45728 -.61171 1.30971 Equal variances not assumed .763 13.345 .459 .34900 .45728 -.63631 1.33431 LDL Equal variances assumed .033 .857 1.158 18 .262 1.92500 1.66303 -1.56889 5.41889 Equal variances not assumed 1.158 17.964 .262 1.92500 1.66303 -1.56940 5.41940
Data Posttest
Independent Samples Test
Levene's Test for Equality of Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper Kolesterol Equal variances
assumed .089 .769 8.184 18 .000 12.88000 1.57372 9.57375 16.18625 Equal variances not assumed 8.184 17.991 .000 12.88000 1.57372 9.57363 16.18637 TG Equal variances assumed 1.460 .243 5.284 18 .000 9.06300 1.71524 5.45942 12.66658 Equal variances not assumed 5.284 16.672 .000 9.06300 1.71524 5.43874 12.68726 HDL Equal variances assumed 1.279 .273 -12.132 18 .000 -8.01500 .66065 -9.40297 -6.62703 Equal variances not assumed -12.132 12.066 .000 -8.01500 .66065 -9.45355 -6.57645 LDL Equal variances assumed .096 .761 10.632 18 .000 8.74300 .82233 7.01536 10.47064 Equal variances not assumed 10.632 17.943 .000 8.74300 .82233 7.01496 10.47104
UJI EFEK PERLAKUAN
Teh Hijau
Paired Samples Test
Paired Differences t df Sig. (2-tailed) 95% Confidence Interval of the Difference Mean Std. Deviation Std. Error
Mean Lower Upper
Pair 1 Kolesterol Total Pretest (mg/dl) - Kolesterol Total Posttest (mg/dl)
124.06100 5.78180 1.82837 119.92495 128.19705 67.853 9 .000
Pair 2 Trigliserida Pretest (mg/dl) - Trigliserida Posttest (mg/dl) 82.18700 5.82701 1.84266 78.01861 86.35539 44.602 9 .000 Pair 3 LDL Pretest (mg/dl) - LDL Postetst (mg/dl) -45.11100 1.73624 .54905 -46.35303 -43.86897 -82.162 9 .000 Pair 4 HDL Pretest (mg/dl) - HDL Posttest (mg/dl) 65.55900 4.17335 1.31973 62.57356 68.54444 49.676 9 .000
Teh Putih
Paired Samples Test
Paired Differences t df Sig. (2-tailed) 95% Confidence Interval of the Difference Mean Std. Deviation Std. Error
Mean Lower Upper
Pair 1 Kolesterol Total Pretest (mg/dl) - Kolesterol Total Posttest (mg/dl)
106.48000 2.78034 .87922 104.49106 108.46894 121.107 9 .000
Pair 2 Trigliserida Pretest (mg/dl) - Trigliserida Posttest (mg/dl) 74.20000 5.85617 1.85188 70.01075 78.38925 40.067 9 .000 Pair 3 LDL Pretest (mg/dl) - LDL Postetst (mg/dl) -36.74700 1.17171 .37053 -37.58519 -35.90881 -99.175 9 .000 Pair 4 HDL Pretest (mg/dl) - HDL Posttest (mg/dl) 58.74100 4.72635 1.49460 55.35997 62.12203 39.302 9 .000
ANALISIS DIFFERENCE
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
Kolesterol Teh Putih 10 106.4800 2.78034 .87922
Teh Hijau 10 124.0610 5.78180 1.82837
Trigliserida Teh Putih 10 74.2000 5.85617 1.85188
Teh Hijau 10 82.1870 5.82701 1.84266
HDL Teh Putih 10 -36.7470 1.17171 .37053
Teh Hijau 10 -45.1110 1.73624 .54905
LDL Teh Putih 10 58.7410 4.72635 1.49460
Teh Hijau 10 65.5590 4.17335 1.31973
Independent Samples Test
Levene's Test for Equality of
Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper
Kolesterol Equal variances assumed
4.978 .039 -8.666 18 .000 -17.58100 2.02878 -21.84331 -13.31869
Equal variances not assumed
-8.666 12.951 .000 -17.58100 2.02878 -21.96560 -13.19640
Trigliserida Equal variances assumed .038 .847 -3.057 18 .007 -7.98700 2.61245 -13.47555 -2.49845 Equal variances not assumed -3.057 18.000 .007 -7.98700 2.61245 -13.47556 -2.49844 HDL Equal variances assumed .120 .733 12.627 18 .000 8.36400 .66238 6.97239 9.75561 Equal variances not assumed 12.627 15.789 .000 8.36400 .66238 6.95830 9.76970 LDL Equal variances assumed .012 .913 -3.419 18 .003 -6.81800 1.99387 -11.00697 -2.62903 Equal variances not assumed -3.419 17.728 .003 -6.81800 1.99387 -11.01158 -2.62442
Lampiran 6. Analisis Statistik Berat Badan dan Sisa Pakan
Deskriptif BB Pretest
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
BB Teh Putih 10 211.40 4.033 1.275
Teh Hijau 10 208.70 6.667 2.108
Deskriptif BB Posttest
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
BB Teh Putih 10 217.30 3.268 1.033
Teh Hijau 10 215.00 7.118 2.251
Deskriptif Rerata Sisa Pakan Selama Penelitian
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
Pakan Teh Putih 10 7.5714 .39412 .12463
Komparasi BB Pretest
Independent Samples Test
Levene's Test for Equality of Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper
BB Equal variances assumed 4.492 .048 1.096 18 .288 2.700 2.464 -2.477 7.877 Equal variances not assumed 1.096 14.809 .291 2.700 2.464 -2.558 7.958 Komparasi BB Posttest
Independent Samples Test
Levene's Test for Equality of Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper
BB Equal variances assumed 8.222 .010 .929 18 .365 2.300 2.477 -2.904 7.504 Equal variances not assumed .929 12.632 .370 2.300 2.477 -3.067 7.667
Komparasi Sisa Pakan
Independent Samples Test
Levene's Test for Equality of Variances
t-test for Equality of Means
95% Confidence Interval of the Difference F Sig. t df Sig. (2-tailed) Mean Difference Std. Error
Difference Lower Upper Pakan Equal variances
assumed
.066 .800 -1.010 18 .326 -.17143 .16977 -.52810 .18524
Equal variances not assumed
Lampiran 7. Dokumentasi Penelitian
Vaccum Rotary Evaporator
Tempat Pakan Tikus, Pipet, Anestesi, Mikropipet Kapiler Hematokrit, Sonde, Tabung EDTA
Kandang Tikus dan Tempat Minum Tikus