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BAB VII SIMPULAN DAN SARAN

7.2 Saran

1. Perlu dilakukan penelitian lebih lanjut agar media ini dapat dijadikan sebagai media alternatif uji sensitivitas antibiotik semua jenis dan dapat diproduksi secara komersial.

2. Karena kemudahan dalam pengadaan bahan serta pembuatan media ACMC, ACMHb, dan ACMCHb sebagai media uji sensitivitas, diharapkan uji standar rutin terhadap Haemophilus influenzae dapat dilakukan mengingat Haemophilus influenzae merupakan patogen penting.

DAFTAR PUSTAKA

1. Generic protocol for population-based surveillance of Haemophilus

influenzae type B. World Health Organization. 1997. WHO/VRD/GEN/95.05.

2. WHO. Haemophilus influenzae Type B (HiB)(internet). c2005(diupdate tahun 2005 Desember; diakses pada 5 Desember 2011). Dapat diakses di : http://www.who.int/mediacentre/factsheets/fs294/en/index.html

3. Kementrian Kesehatan RI. Jakarta (Indonesia) : Jendela Epidemiologi; 2010

4. Mansjoer, Arief, dkk. Kapita Selekta Kedokteran, Edisi III Jilid II. Jakarta :Media Aeskulapius FKUI ; 2000

5. Elma Krumwiede And Ann G. Kuttner, M.D. A Growth Inhibitory

Substance For The Influenzae Group Of Organisms In The Blood Of Various Animal Species The Use O]~ The Blood 01~ Various Animals As A Selective Medium For The Detection Of Hemolytic Streptococci In Throat Cultures. 1973

6. Wikipedia. Complement System. c2012[di-update pada Februari 2012; diakses pada 9 Februari 2012]. Dapat diakses di : http://en.wikipedia.org/wiki/Complement_system

7. Qingyou Li, Marcia Gordon, Chuanhai Cao, Kenneth E Ugen, and DaveMorga. Improvement of a low pH antigen-antibody dissociation

procedure for ELISA measurement of circulating anti-Aβ antibodies.

at: http://www.biomedcentral.com/1471-2202/8/22

8. Kuhnert P, Christensen H (editors). Pasteurellaceae: Biology, Genomics

and Molecular Aspects. Caister Academic Press. 2008. ISBN

9. Jawetz, Melnick, and Adelberg. Mikrobiologi Kedokteran. Terjemahan oleh Huriawati Hartanto…(et al). 2007. Jakarta : Penerbit Buku Kedokteran EGC. 2004.

10. Ryan KJ, Ray CG (editors). Sherris Medical Microbiology (4th ed.).

McGraw Hill. Pp. 396 – 401. 2004. ISBN 0838585299.

11. Kenneth, T., Todar’s Online Textbook of Bacteriology. [di-update pada 2008 ; diakses pada 9 februari 2012]. Dapat diakses di :

http://textbookofbacteriology.net/haemophilus.html

12. Clinical Microbiology II, Class Lecture. NSCC, 2010

13. Koneman, E.W., Stephen D. Allen et al. Color Atlas and textbook of

Diagnostic Microbiology (2nd ed.). J.B. Lippincott Company; 1986.

14. Hemin at Dorland's Medical Dictionary

15. Wikipedia. Nicotinamide Adenine Dinukleotida. c2011[di-update pada Desember 2011; diakses pada 11 Januari 2012]. Dapat diakses di http://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide

16. Forbes, B., Sahm, D. and Weissfeld, A. Bailey & Scott's Diagnostic

Microbiology. 2007.

17. Vandepitte, J. Verhaegen,et al. Prosedur Laboratorium Dasar untuk

Bakteriologi Klinis Ed.2. Terjemahan oleh Lyana Setiawan.

Jakarta:EGC.2010

18. Vandepitte, J., J.Verhaegen, et all. Basic Laboratory Procedures in Clinical

Biology, 2nd Ed. : 105. WHO. 2003.

19. Clinical and Laboratory Standards Institute, Performance Standards for

Antimicrobial Susceptibility Testing, M100-S16 Vol.26, No. 3, CLSI,

Villanova, Pa., 2007.

20. Yeh, E., Benjamin A. Pinsky, Niaz Banaei, Ellen Jo Baron. Hair Sheep

Blood, Citrated or Defibrinated, Fulfills All Requirements of Blood Agar for Diagnostic Microbiology Laboratory Tests

21. Brune, T., K. Hannemann-Pohl, K. Nißle, N. Ecker, and H. Garritsen.

Quality, Stability, and Safety Data of Packed Red Cells and Plasma Processed by Gravity Separation Using a New Fully Integrated Hollow-Fibre Filter Device. 2009.

22. Jurnal Sains Kimia (Journal of Chemical Science) volume 7,nomor 2:44:50. Universitas Sumatra Utara. 2003.

23. Wood and Washington. In Murray, Baron, Pfaller, Tenover and Yolken (ed.), Manual of clinical microbiology, 6th ed. American Society for

Microbiology, Washington, D.C. 1995.

24. Setiawati Arini, Suyatna F.D., Gan Sulistia. Farmakologi dan Terapi Edisi

5: 2. Jakarta : Departemen Farmakologi dan Terapeutik Fakultas

Kedokteran Universitas Indonesia.2007.

25. Mueller J. H. and Hinton Jane. Proc. Soc. Exp. Biol. and Med. 48. 330-333.1941.

26. Cohen J. Weighted kappa: Nominal Scale Agreement with Provision for

Scaled Disagreement or Partial Credit. Psychological Bulletin .

70:213-20. 1968

27. Wikipedia. Hemoglobin. c2011[di-update pada Desember 2011; diakses pada 11 Januari 2012]. Dapat diakses di http://id.wikipedia.org/wiki/Hemoglobin

52 Lampiran 2. Diameter zona inhibisi antibiotik pada berbagai macam media uji

Strain Haemophilus

influenzae

Diameter zona inhibisi antibiotik Amoksisilin-asam klavulanat pada berbagai

media

Interpretasi diameter zona inhibisi antibiotik Amoksisilin-asam klavulanat berdasarkan CLSI

HTM ACD ACM ACMHbC HTM ACD ACM ACMHbC

atcc 19.00 19.00 19.00 18.50 resisten resisten resisten resisten atcc 20.00 16.00 15.00 17.00 sensitif resisten resisten resisten c171 25.00 28.00 20.00 25.00 sensitif sensitif sensitif sensitif c171 28.00 20.00 24.00 26.00 sensitif sensitif sensitif sensitif c104 29.00 27.00 24.00 25.00 sensitif sensitif sensitif sensitif c104 32.00 24.00 26.00 30.00 sensitif sensitif sensitif sensitif c173 40.00 32.00 31.00 34.00 sensitif sensitif sensitif sensitif c173 35.00 40.00 30.00 31.00 sensitif sensitif sensitif sensitif c120 29.00 25.00 25.00 35.00 sensitif sensitif sensitif sensitif c120 27.00 23.00 23.00 35.00 sensitif sensitif sensitif sensitif c086 35.00 30.00 28.00 31.00 sensitif sensitif sensitif sensitif c086 37.00 29.00 29.00 29.00 sensitif sensitif sensitif sensitif c070 24.00 22.00 24.00 23.00 sensitif sensitif sensitif sensitif c070 22.00 25.00 22.00 24.00 sensitif sensitif sensitif sensitif c141 30.00 24.00 26.00 24.00 sensitif sensitif sensitif sensitif c141 24.00 24.00 27.00 35.00 sensitif sensitif sensitif sensitif c107 36.00 35.00 30.00 36.00 sensitif sensitif sensitif sensitif c107 36.00 35.00 33.00 35.00 sensitif sensitif sensitif sensitif c128 21.00 20.00 19.00 20.00 sensitif sensitif resisten sensitif c128 21.00 19.00 22.00 22.00 sensitif resisten sensitif sensitif c241 19.00 17.00 17.00 19.00 resisten resisten resisten resisten c241 19.00 17.00 17.00 18.00 resisten resisten resisten resisten

53 Strain

Haemophilus influenzae

Diameter zona inhibisi antibiotik tetrasiklin pada berbagai media

Interpretasi diameter zona inhibisi antibiotik Tetrasiklin berdasarkan CLSI

HTM ACD ACM ACMHbC HTM ACD ACM ACMHbC

atcc 19.00 18.00 17.00 16.00 resisten resisten resisten resisten atcc 20.00 15.00 18.00 16.00 resisten resisten resisten resisten c171 31.00 29.00 30.00 30.00 sensitif sensitif sensitif sensitif c171 34.00 27.00 34.00 30.00 sensitif resisten sensitif sensitif c104 38.00 29.00 29.00 34.00 sensitif sensitif sensitif sensitif c104 35.00 27.00 30.00 30.00 sensitif resisten sensitif sensitif c173 34.00 34.00 32.00 33.00 sensitif sensitif sensitif sensitif c173 32.00 31.00 29.00 31.00 sensitif sensitif sensitif sensitif c120 31.00 28.00 30.00 30.00 sensitif resisten sensitif sensitif c120 32.00 28.00 29.00 29.00 sensitif resisten sensitif sensitif c086 36.00 28.00 32.00 31.00 sensitif resisten sensitif sensitif c086 37.00 36.00 31.00 32.00 sensitif sensitif sensitif sensitif c070 30.00 26.00 26.00 24.00 sensitif resisten resisten resisten c070 27.00 27.00 27.00 26.00 resisten resisten resisten resisten c141 29.00 25.00 26.00 29.00 sensitif resisten resisten sensitif c141 29.00 25.00 30.00 26.00 sensitif resisten sensitif resisten c107 36.00 30.00 32.00 33.00 sensitif sensitif sensitif sensitif c107 36.00 33.00 34.00 35.00 sensitif sensitif sensitif sensitif c128 18.00 18.00 17.00 16.00 resisten resisten resisten resisten c128 20.00 17.00 21.00 18.00 resisten resisten resisten resisten c241 17.00 16.00 17.00 17.00 resisten resisten resisten resisten c241 18.00 16.00 20.00 18.00 resisten resisten resisten resisten

54 Strain

Haemophilus influenzae

Diameter zona inhibisi antibiotik Seftriakson pada berbagai media

Interpretasi diameter zona inhibisi antibiotik Seftriakson berdasarkan CLSI

HTM ACD ACM ACMHbC HTM ACD ACM ACMHbC

atcc 33.00 23.00 35.00 33.00 sensitif resisten sensitif sensitif atcc 33.00 25.00 30.00 30.00 sensitif resisten sensitif sensitif c171 28.00 30.00 26.00 26.00 sensitif sensitif sensitif sensitif c171 25.00 22.00 32.00 25.00 resisten resisten sensitif resisten c104 41.00 30.00 31.00 26.00 sensitif sensitif sensitif sensitif c104 40.00 30.00 31.00 36.00 sensitif sensitif sensitif sensitif c173 45.00 45.00 42.00 43.00 sensitif sensitif sensitif sensitif c173 46.00 45.00 40.00 42.00 sensitif sensitif sensitif sensitif c120 35.00 32.00 32.00 36.00 sensitif sensitif sensitif sensitif c120 34.00 32.00 30.00 31.00 sensitif sensitif sensitif sensitif c086 42.00 37.00 39.00 41.00 sensitif sensitif sensitif sensitif c086 40.00 38.00 41.00 42.00 sensitif sensitif sensitif sensitif c070 28.00 28.00 32.00 32.00 sensitif sensitif sensitif sensitif c070 27.00 31.00 32.00 31.00 sensitif sensitif sensitif sensitif c141 31.00 32.00 32.00 31.00 sensitif sensitif sensitif sensitif c141 30.00 32.00 35.00 33.00 sensitif sensitif sensitif sensitif c107 46.00 34.00 34.00 42.00 sensitif sensitif sensitif sensitif c107 46.00 35.00 37.00 42.00 sensitif sensitif sensitif sensitif c128 36.00 37.00 34.00 34.00 sensitif sensitif sensitif sensitif c128 34.00 34.00 37.00 37.00 sensitif sensitif sensitif sensitif c241 25.00 23.00 21.00 25.00 resisten resisten resisten resisten c241 25.00 22.00 24.00 25.00 resisten resisten resisten resisten

55 Strain

Haemophilus influenzae

Diameter zona inhibisi antibiotik Kloramfenikol pada berbagai media

Interpretasi diameter zona inhibisi antibiotik Kloramfenikol berdasarkan CLSI

HTM ACD ACM ACMHbC HTM ACD ACM ACMHbC

atcc 37.00 30.00 35.00 34.00 sensitif sensitif sensitif sensitif atcc 36.00 32.00 30.00 34.00 sensitif sensitif sensitif sensitif c171 37.00 31.00 33.00 35.00 sensitif sensitif sensitif sensitif c171 40.00 35.00 36.00 35.00 sensitif sensitif sensitif sensitif c104 43.00 35.00 34.00 35.00 sensitif sensitif sensitif sensitif c104 38.00 34.00 34.00 37.00 sensitif sensitif sensitif sensitif c173 40.00 38.00 36.00 38.00 sensitif sensitif sensitif sensitif c173 40.00 33.00 35.00 36.00 sensitif sensitif sensitif sensitif c120 28.00 30.00 25.00 25.00 resisten sensitif resisten resisten c120 26.00 22.00 26.00 24.00 resisten resisten resisten resisten c086 35.00 38.00 38.00 34.00 sensitif sensitif sensitif sensitif c086 41.00 36.00 37.00 34.00 sensitif sensitif sensitif sensitif c070 27.00 25.00 28.00 25.00 resisten resisten resisten resisten c070 25.00 27.00 25.00 28.00 resisten resisten resisten resisten c141 33.00 32.00 30.00 30.00 sensitif sensitif sensitif sensitif c141 34.00 32.00 30.00 32.00 sensitif sensitif sensitif sensitif c107 41.00 34.00 36.00 36.00 sensitif sensitif sensitif sensitif c107 40.00 36.00 38.00 36.00 sensitif sensitif sensitif sensitif c128 41.00 36.00 38.00 35.00 sensitif sensitif sensitif sensitif c128 42.00 35.00 40.00 36.00 sensitif sensitif sensitif sensitif c241 40.00 34.00 34.00 34.00 sensitif sensitif sensitif sensitif c241 40.00 33.00 32.00 32.00 sensitif sensitif sensitif sensitif

56 Strain

Haemophilus influenzae

Diameter zona inhibisi antibiotik Kotrimoksazol pada berbagai media

Interpretasi diameter zona inhibisi antibiotik Kotrimoksazol berdasarkan CLSI

HTM ACD ACM ACMHbC HTM ACD ACM ACMHbC

atcc 32.00 30.00 35.00 35.00 sensitif sensitif sensitif sensitif atcc 15.00 15.00 15.00 15.00 resisten resisten resisten resisten c171 29.00 26.00 30.00 31.00 sensitif sensitif sensitif sensitif c171 29.00 21.00 34.00 31.00 sensitif sensitif sensitif sensitif c104 32.00 32.00 29.00 31.00 sensitif sensitif sensitif sensitif c104 38.00 26.00 27.00 35.00 sensitif sensitif sensitif sensitif c173 38.00 39.00 38.00 38.00 sensitif sensitif sensitif sensitif c173 38.00 40.00 38.00 36.00 sensitif sensitif sensitif sensitif c120 33.00 31.00 33.00 31.00 sensitif sensitif sensitif sensitif c120 32.00 32.00 32.00 32.00 sensitif sensitif sensitif sensitif c086 37.00 36.00 37.00 37.00 sensitif sensitif sensitif sensitif c086 38.00 37.00 38.00 38.00 sensitif sensitif sensitif sensitif c070 31.00 31.00 33.00 32.00 sensitif sensitif sensitif sensitif c070 28.00 32.00 30.00 34.00 sensitif sensitif sensitif sensitif c141 32.00 32.00 34.00 31.00 sensitif sensitif sensitif sensitif c141 30.00 34.00 35.00 32.00 sensitif sensitif sensitif sensitif c107 40.00 40.00 38.00 33.00 sensitif sensitif sensitif sensitif c107 37.00 39.00 35.00 36.00 sensitif sensitif sensitif sensitif c128 36.00 36.00 21.00 34.00 sensitif sensitif sensitif sensitif c128 37.00 25.00 37.00 36.00 sensitif sensitif sensitif sensitif c241 16.00 16.00 22.00 19.00 sensitif sensitif sensitif sensitif c241 16.00 34.00 34.00 20.00 sensitif sensitif sensitif sensitif

Lampiran 3. Data kesesuaian uji kepekaan antibiotik amoksisilin-asam klavulanat pada media ACD, ACM, ACMHC dengan HTM

Case Processing Summary

Cases

Valid Missing Total N Percent N Percent N Percent amocl_htm_ord * amocl_acd_ord 22 100.0% 0 .0% 22 100.0% amocl_htm_ord * amocl_acm_ord 22 100.0% 0 .0% 22 100.0% amocl_htm_ord * amocl_acmcHb_ord 22 100.0% 0 .0% 22 100.0% amocl_htm_ord * amocl_acd_ord Crosstab Count amocl_acd_ord Total resisten sensitif amocl_htm_ord resisten 3 0 3 sensitif 2 17 19 Total 5 17 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .699 .194 3.437 .001 N of Valid Cases 22

a. Not assuming the null hypothesis.

amocl_htm_ord * amocl_acm_ord Crosstab Count amocl_acm_ord Total resisten sensitif amocl_htm_ord resisten 3 0 3 sensitif 2 17 19 Total 5 17 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .699 .194 3.437 .001 N of Valid Cases 22

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

amocl_htm_ord * amocl_acmcHb_ord Crosstab Count amocl_acmcHb_ord Total resisten sensitif amocl_htm_ord resisten 3 0 3 sensitif 1 18 19 Total 4 18 22

Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .831 .163 3.954 .000

N of Valid Cases 22

a. Not assuming the null hypothesis.

Lampiran 4. Data kesesuaian uji kepekaan antibiotik tetrasiklin pada media ACD, ACM, ACMHC dengan HTM

Case Processing Summary

Cases

Valid Missing Total N Percent N Percent N Percent tetra_htm_ord * tetra_acd_ord 22 100.0% 0 .0% 22 100.0% tetra_htm_ord * tetra_acm_ord 22 100.0% 0 .0% 22 100.0% tetra_htm_ord * tetra_acmcHb_ord 22 100.0% 0 .0% 22 100.0% tetra_htm_ord * tetra_acd_ord Crosstab Count tetra_acd_ord Total resisten sensitif tetra_htm_ord resisten 7 0 7 sensitif 8 7 15 Total 15 7 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .358 .139 2.189 .029 N of Valid Cases 22

a. Not assuming the null hypothesis.

tetra_htm_ord * tetra_acm_ord Crosstab Count tetra_acm_ord Total resisten sensitif tetra_htm_ord resisten 7 0 7 sensitif 2 13 15 Total 9 13 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .805 .129 3.851 .000

N of Valid Cases 22

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

tetra_htm_ord * tetra_acmcHb_ord Crosstab Count tetra_acmcHb_ord Total resisten sensitif tetra_htm_ord resisten 7 0 7 sensitif 2 13 15 Total 9 13 22

Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .805 .129 3.851 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

Lampiran 5. Data kesesuaian uji kepekaan antibiotik kotrimoksazol pada media ACD, ACM, ACMHC dengan HTM

Case Processing Summary

Cases

Valid Missing Total N Percent N Percent N Percent kotri_htm_ord * kotri_acd_ord 22 100.0% 0 .0% 22 100.0% kotri_htm_ord * kotri_acm_ord 22 100.0% 0 .0% 22 100.0% kotri_htm_ord * kotri_acmcHb_ord 22 100.0% 0 .0% 22 100.0% kotri_htm_ord * kotri_acd_ord Crosstab Count kotri_acd_ord Total resisten sensitif kotri_htm_ord resisten 1 0 1 sensitif 0 21 21 Total 1 21 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

kotri_htm_ord * kotri_acm_ord Crosstab Count kotri_acm_ord Total resisten sensitif kotri_htm_ord resisten 1 0 1 sensitif 0 21 21 Total 1 21 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

kotri_htm_ord * kotri_acmcHb_ord Crosstab Count kotri_acmcHb_ord Total resisten sensitif kotri_htm_ord resisten 1 0 1 sensitif 0 21 21 Total 1 21 22

Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

Lampiran 6. Data kesesuaian uji kepekaan antibiotik seftriakson pada media ACD, ACM, ACMHC dengan HTM

Case Processing Summary

Cases

Valid Missing Total N Percent N Percent N Percent seft_htm_ord * seft_acd_ord 22 100.0% 0 .0% 22 100.0% seft_htm_ord * seft_acm_ord 22 100.0% 0 .0% 22 100.0% seft_htm_ord * seft_acmcHb_ord 22 100.0% 0 .0% 22 100.0% seft_htm_ord * seft_acd_ord Crosstab Count seft_acd_ord Total resisten sensitif seft_htm_ord resisten 3 0 3 sensitif 2 17 19 Total 5 17 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .699 .194 3.437 .001 N of Valid Cases 22

a. Not assuming the null hypothesis.

seft_htm_ord * seft_acm_ord Crosstab Count seft_acm_ord Total resisten sensitif seft_htm_ord resisten 2 1 3 sensitif 0 19 19 Total 2 20 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .776 .214 3.733 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

seft_htm_ord * seft_acmcHb_ord Crosstab Count seft_acmcHb_ord Total resisten sensitif seft_htm_ord resisten 3 0 3 sensitif 0 19 19 Total 3 19 22

Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

Lampiran 7. Data kesesuaian uji kepekaan antibiotik kloramfenikol pada media ACD, ACM, ACMHC dengan HTM

Case Processing Summary

Cases

Valid Missing Total N Percent N Percent N Percent klor_htm_ord * klor_acd_ord 22 100.0% 0 .0% 22 100.0% klor_htm_ord * klor_acm_ord 22 100.0% 0 .0% 22 100.0% klor_htm_ord * klor_acmcHb_ord 22 100.0% 0 .0% 22 100.0% klor_htm_ord * klor_acd_ord Crosstab Count klor_acd_ord Total resisten sensitif klor_htm_ord resisten 3 1 4 sensitif 0 18 18 Total 3 19 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa .831 .163 3.954 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

klor_htm_ord * klor_acm_ord Crosstab Count klor_acm_ord Total resisten sensitif klor_htm_ord resisten 4 0 4 sensitif 0 18 18 Total 4 18 22 Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

b. Using the asymptotic standard error assuming the null hypothesis.

klor_htm_ord * klor_acmcHb_ord Crosstab Count klor_acmcHb_ord Total resisten sensitif klor_htm_ord resisten 4 0 4 sensitif 0 18 18 Total 4 18 22

Symmetric Measures

Value Asymp. Std. Errora Approx. Tb Approx. Sig. Measure of Agreement Kappa 1.000 .000 4.690 .000 N of Valid Cases 22

a. Not assuming the null hypothesis.

Lampiran 8. Dokumentasi penelitian

Persiapan alat dan bahan Pembuatan Berbagai Media Agar

Menumbuhkan koloni kuman Streak kuman 0,5 McFarland pada

Murni berbagai media agar

Lampiran 9. Biodata mahasiswa

Nama : Radith Aulia

NIM : G2A008148

Tempat/tanggal lahir : Pekalongan/30 April 1990 Jenis kelamin : Laki-laki

Alamat : Jalan Menoreh Utara XII no 9 Sampangan, Semarang Nomor Telpon : -

Nomor HP : 0853 8553 8773

e-mail : dr.radithaulia@yahoo.com

Riwayat Pendidikan Formal

1. SD : SDN Medono 07 Pekalongan Lulus tahun : 2002 2. SMP : SMP N 1 Pekalongan Lulus tahun : 2005 3. SMA : SMA N 1 Pekalongan Lulus tahun : 2008

4. FK UNDIP : Masuk tahun : 2008

Keanggotaan Organisasi

1.Bidang PSDM Badan Eksekutif Mahasiswa Tahun 2008 s/d 2010 2.Koordinator Bidang Elit Profesional BEM Tahun 2008s/d 2011

Pengalaman penelitian

1. Optimalisasi Agar Coklat Darah Manusia sebagai Media Uji Sensitivitas Antibiotik Terhadap Haemophilus influenzae. Tahun 2012.

Pengalaman presentasi karya ilmiah

1. Radith Aulia. Optimalisasi Agar Coklat Darah Manusia sebagai Media Uji Sensitivitas Antibiotik Terhadap Haemophilus influenzae. Dikti. 2012. Cara presentasi oral

Pengalaman mengikuti lomba karya ilmiah

1. Radith Aulia. Optimalisasi Agar Coklat Darah Manusia sebagai Media Uji Sensitivitas Antibiotik Terhadap Haemophilus influenzae, Dikti, prestasi (didanai Dikti)

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