SIMPULAN DAN SARAN
7.1 Simpulan
Berdasarkan hasil penelitian pemberian ekstrak air ubi jalar ungu pada tikus betina dewasa galur wistar didapatkan simpulan sebagai berikut:
Pemberian ekstrak air ubi jalar ungu dapat menghambat peningkatan kadar MMP-1 pada kulit tikus wistar betina yang diberikan pajanan sinar UVB dengan dosis total 800mJ/cm2 selama 15 hari.
7.2 Saran
Sebagai saran dalam penelitian ini adalah:
1. Perlu melakukan penelitian lebih lanjut untuk mengetahui dosis optimal Ekstrak air ubi jalar ungu terhadap penurunan MMP-1.
2. Selanjutnya diharapkan dapat dilakukan penelitian lebih lanjut dengan manusia sebagai subyeknya, sehingga didapatkan manfaat yang lebih praktis.
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Lampiran 1
Tests of Normality
Kelompok
Kolmogorov-Smirnova Shapiro-Wilk
Statistic df Sig. Statistic df Sig.
MMP_1_pre Aquades .298 9 .120 .801 9 .121
Ekstrak air ubi jalar
ungu .260 9 .181 .765 9 .208
MMP_1_post Aquades .295 9 .123 .773 9 .110
Ekstrak air ubi jalar
ungu .270 9 .157 .803 9 .322
Lampiran 2
Group Statistics
Kelompok N Mean Std. Deviation Std. Error Mean
MMP_1_pre Aquades 9 .2657 .02589 .00863
Ekstrak air ubi ungu 9 .2682 .02715 .00905
MMP_1_post Aquades 9 .3617 .07731 .02577
Ekstrak air ubi ungu 9 .2802 .02751 .00917
Independent Samples Test Levene's Test for
Equality of
Variances t-test for Equality of Means
F Sig. t df Sig. (2-tailed) Mean Differen ce Std. Error Differen ce 95% Confidence Interval of the Difference Lower Upper MMP_1 _pre Equal variances assumed .048 .829 -.204 16 .841 -.00256 .01251 -.02907 .02395 Equal variances not assumed -.204 15.96 4 .841 -.00256 .01251 -.02907 .02396 MMP_1 _post Equal variances assumed 1.657 .216 2.977 16 .009 .08144 .02735 .02346 .13943 Equal variances not assumed 2.977 9.994 .014 .08144 .02735 .02049 .14240
Lampiran 3 Uji t-paired Test
Kelompok = Aquades
Paired Samples Statisticsa
Mean N Std. Deviation Std. Error Mean
Pair 1 MMP_1_pre .2657 9 .02589 .00863
Paired Samples Statisticsa
Mean N Std. Deviation Std. Error Mean
Pair 1 MMP_1_pre .2657 9 .02589 .00863
MMP_1_post .3617 9 .07731 .02577
a. Kelompok = Aquades
Paired Samples Correlationsa
N Correlation Sig.
Pair 1 MMP_1_pre & MMP_1_post 9 .367 .331
a. Kelompok = Aquades
Paired Samples Testa
Paired Differences t df Sig. (2-tailed) Mean Std. Deviatio n Std. Error Mean 95% Confidence Interval of the Difference Lower Upper Pair 1 MMP_1_pre - MMP_1_post -.0960 0 .07195 .02398 -.15131 -.04069 -4.003 8 .004 a. Kelompok = Aquades
Kelompok = Ekstrak air ubi jalar ungu
Paired Samples Statisticsa
Mean N Std. Deviation Std. Error Mean
Pair 1 MMP_1_pre .2682 9 .02715 .00905
MMP_1_post .2802 9 .02751 .00917
Paired Samples Correlationsa
N Correlation Sig.
Pair 1 MMP_1_pre & MMP_1_post 9 -.093 .812
a. Kelompok = Ekstrak air ubi jalar ungu
Paired Samples Testa
Paired Differences t df Sig. (2-tailed) Mean Std. Deviatio n Std. Error Mean 95% Confidence Interval of the Difference Lower Upper Pair 1 MMP_1_pre - MMP_1_post -.0120 0 .04041 .01347 -.04306 .01906 -.891 8 .399
a. Kelompok = Ekstrak air ubi jalar ungu