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Preoperative exercise intervention for patients with prostate, colon and breast

cancer in the Grampians region

Dr Matthew Wallen Prof Fergal Grace

Dr Stephen Brown A/Prof Anna Wong Shee

Luke Evans Dr Jonathan Rawstorn

Dr Jack Harvey Gay Corbett Joylene Fletcher Leanne Storer

Rhys Duncan Lea Marshall

(2)

Background

 Cancer is a major cause of disability and death in Australia with an estimate of 130,000+ new cancer diagnoses in 2017 [1].

 Prostate, breast and colorectal cancer are the three most common cancers (excluding non-melanoma skin cancer) in Australia [1].

 Grampians region an average of over 1300 new diagnoses

each year that is predicted to rise over coming years [2].

(3)

CRITICAL ZONE CRITICAL ZONE

Surgery

Time (weeks) Fitness

Rehabilitation vs Prehabilitation

(4)

Study design

 A randomised controlled trial for prostate, colon and breast cancer patients undergoing surgery.

 Primary outcomes:

 safe (adverse events and serious adverse events),

 feasible (adherence and compliance) and

 effective (ventilatory threshold)

 Secondary outcomes

e.g. grip strength, cardiopulmonary testing, self-reported wellbeing

(5)

Confirmed diagnosis & requires surgery

Initial Assessment: Sub-maximal Exercise Test

& measures

Stratified (Cancer Type) & randomised

Prehabilitation Control

Pre surgery Re-assessment: Sub-maximal Exercise Test & measures

30 day post surgery Re-assessment: Sub- maximal Exercise Test & measures

Recruitment 9/18 – 3/19

(6)

Intervention: FITT

 Frequency: 2 x per week for 4+ weeks

 Intensity:

 Aerobic exercise: 60-80% of peak heart rate achieved during initial exercise test.

 Resistance exercise: 11-13 on the rating of perceived exertion scale.

 Time: 60 minutes

 Type:

 30 minutes of aerobic exercise

 30 minutes of resistance exercise

(7)

Thank you

AC K N O W L E D G E M E N T S

Western Alliance

(8)

References

1. AIHW, Cancer in Australia 2017, in Cancer series no. 101. Cat. no. CAN 100. 2017:

Canberra: AIHW.

2. Grampians Intergrated Cancer Service. 2018. Grampians Intergrated Cancer Service.

[ONLINE] Available at: http://www.gics.com.au/. [Accessed 10 May 2018].

3. Cabilan, C.J., S. Hines, and J. Munday, The effectiveness of prehabilitation or preoperative exercise for surgical patients: a systematic review. JBI Database System Rev Implement Rep, 2015. 13(1): p. 146-87.

4. Punt IM, Bongers B.C., Van Beijsterveld C.A., Hulzebos H.J., Dronkers J.J., Van Meeteren N.L. Surgery: moving people, improving outcomes. In: Geriatrics. Hyderabad:

Avid Science; 2016. p. 2-30.

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