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m l h i s t h e s i s i s c o q c e r n e d ? r i r n a r i l ; ! ~ ~ i - t h a s t u d y o f t h e o x L d a t i o n o i nromatic s t e r o i l s em?lo::i.nq either c h r ~ m i u n tr i o x i d e - a q u e o u s acetic a c i d o r c k r o ~ ~ i u m t r i o x i d e - a q u e o u ~ s u l p h u r i c a . c i d - z c e t o n r . ? mixtures.
T h e n - 7 t u r e o-Lr t h e c h r o m i c t~.cici o x i d a t i o n o f v - ? r i 5 u s f u n c t i o n a l c r o u n s i . 5 d i s c u s o n d itrrt xnL this i e folio-ed Sg a n outlize of t h e
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e t e r o i d e c o r t a l n ~ n , < 2 z t r c ~ n r e l e c t r o n - d o n a . t i n 7 C , - s u b s t i t u e n t , s u c h as
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aromntic steroid also contained a s i ~ b s t i t ~ l e n t at C
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.,, . . h e n a C - - m e t h o x y l z u i s t i t u - n t T,ves present, the 6-0x0-ring-A 5
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~ e 3 . k C,!-electron-donating Z r o u ? , eu-ch as a - c e t o x , y l .,
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The o x i d a t i o n o f a ring-:: 3rorn::j;:c r t e r o i d c : > n t ; ? i n i n : ; z C - m t h o o y l 2
s u b s t i t u e n t ~ ~ i v e a n almost r ; u a n t L t z t i v e yield (17 t3.- c o r r s s p o n d i n , r
. ' l y r i r o x y - 5 - : ~ e t l ! ~ x y e ~ i 1 . ? - 1 , J / , 5 ( ? 0 ) - t ~ ? . e n - I l - o n e (123
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T h y s i s a l a n d c h e a i c , z l evidence a r e T r e ~ z n t e d tc ~ h 0 1 , : t h , z t t h i . ~ p r o d u c t i~ i n f a c t t h e 3 P - h ; f d r o x y e ? i m e ~ 3 n d ;: r e a c t i n r . ~ s t h v ! a y f o r i t s f o r m a t i o n i s n r o n o s e d .:'in e x a r n i n a . t i o n o f t h e o x i d c ? t i o n p- ducts o f e r i n g - 3 a.rorn;iti-c
s t e r o i d a n d a r i n ~ ; - C sronrtic : : t c r o i h s ! - . o - e 3 t h a t n o ketols v c r e f o r m e d .
