Syllabus
BPH 313 Pharmacology-II 3 credits
For Mid-Term Examination
1. Antidiabetic drugs:
a) Introduction and classification of diabetes.
b) Hyperglycemia and hypoglycemia.
c) Introduction, classification, chemistry, mode of action, structure-activity relationship, pharmcokinetics, indications, contraindications, dose, adverse effects and drug interaction of following individual classes of drugs:Oral hypoglycemic agents: sulfonylureas, biguanides. Hormone preparations: Insulin
d) Management of diabetes mellitus.
2. Cardiovascular drugs:
Functions and diseases of heart: Arrhythmia, atheroma, ischemia, angina pectoris, coronary thrombosis, myocardial infarction, arteriosclerosis, arteriosclerosis, hypertension and congestive heart failure. Introduction, classification, chemistry, mode of action, structure-activity relationship, pharmacokinetics, indications, contraindications, dose, adverse effects and drug interaction of following individual class of drugs:
a) Cardiac glycosides.
b) Antihypertensives: -Blockers, vasodialators, Ca-channel blocking agents, ACE inhibitors.
c) Antiarrhythmic drugs.
d) Diuretics: Cardiac anhydrase inhibitors, low and high ceiling diuretics, potassium sparing diuretics and osmotic diuretics.
For Final Examination
3. Antibacterial and antifungal agents: Introduction, classification, chemistry, mode of action, structure- activity relationship, pharmacokinetics, indications, contraindications, dose, adverse effects and drug interaction of following individual classes of drugs:
a. Drugs which interface with synthesis and action of folate b. -Lactum antibiotics
c. Drugs affecting bacterial protein synthesis d. Drugs affecting the enzyme topoisomerase-1.
e. Miscellaneous antibacterial Agents
f. Antitubercular agents g. Antileprosy drugs h. Antifungal agents.
4. Drugs used in tropical diseases: Introduction, classification, chemistry, mode of action, structure activity relationship (SAR), pharmacokinetics, indications, contraindications, dose, adverse effects and drug intraction of the following classes of drugs:
(a) Antiamoebic drugs, (b) Antimalarial Agents, (c) Anthelmentics (d) Drugs used in enteric fever, (e) Drugs used in diarrhoea and cholera.
Recommended Books:
1. Goodman & Gillman’s Pharmacological Basis of Therapeutics- Hardman, Joel G., 10th edition, Mcgraw-Hill Incorporated.
2. Basic and Clinical Pharmacology- Bertram G. Katzung, 9th edition, Mc Graw Hill Companies.
3. Clinical Pharmacology- D. R. Laurence, P. N. Bennett and M. J. Brown, 9th edition, Churchill Livingstone.
4. Clinical Pharmacy and Therapeutics, Roger walker and Clive Edwards, 3rd edition, Churchill Livingstone.
