Pengaruh Pemberian Vitamin D Terhadap Perbaikan Foto Toraks Pada Pasien TB Paru Etnik Batak Di Kota Medan Dihubungkan Dengan Polimorfisme ApaI Gen Reseptor Vitamin D

(1)

(2)

LAMPIRAN DOKUMEN PENELITIAN

Gmbr 1. Isolasi DNA

Gambar 2. RFLP

Gambar 4. KIT Vitamin D

(3)

Gambar 6. Persiapan RFLP

Gambar 7. Penomoran sampel

Gambar 8: Kit Vitamin D

(4)

Gambar10. Meemberikan vitamin D ke sampel

Gambar 11. Sampel Minum Vitamin D

Gambar: PCR

(5)

LAMPIRAN : PENGOLAHAN DATA BERDASARKAN SPSS

1. KARAKTERISTIK RESPONDEN

Umur Responden Kelompok Vitamin D

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

1

11

52.4

2

9

42.9

95.2

3

1

4.8

100.0 Total

21

100.0

100.0 Umur Responden Kelompok Plasebo

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

18-34

4

19.0

19.0 35-52

9

42.9

61.9 53-69

8

38.1

100.0 Total

21

100.0

100.0 Statistics

Umur Responden Kelompok Plasebo

N

Valid

21 Missing

0 Mean

46.19 Median

49.00 Std. Deviation

14.500 Statistics

Umur Responden Kelompok Vitamin D

N

Valid

21 Missing

0 Mean

34.00 Median

31.00

(6)

Jenis kelamin responden Kelompok Vitamin D

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

laki-laki

13

61.9

61.9 perempuan

8

38.1

100.0 Total

21

100.0

100.0 Jenis Kelamin Responden Kelompok Plasebo

Frequency Percent Valid Percent Cumulative

Percent

Valid

laki-laki 13 61.9 61.9 61.9

perempuan 8 38.1 38.1 100.0

Total 21 100.0 100.0

Pekerjaan Responden Kelompok Vitamin D

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

mahasiswa

3

14.3

14.3 bekerja

13

61.9

76.2 tidak

bekerja

5

23.8

100.0 Total

21

100.0

100.0 Pekerjaan Responden Kelompok Plasebo

Percent

Valid

mahasiswa 1 4.8 4.8 4.8

bekerja 13 61.9 61.9 66.7

tidak bekerja 7 33.3 33.3 100.0

(7)

2. STATUS VITAMIN D

Kadar Vitamin D Sebelum intervensi Pada Kelompok Vitamin D

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

Defisiensi

3

14.3

14.3 insufisiensi

6

28.6

42.9 optimal

12

57.1

100.0 Total

21

100.0

100.0 Kadar Vitamin D Sebelum Intervensi Kelompok Plasebo

Frequency

Percent

Valid Percent

Cumulative

Percent

Valid

Defisiensi

2

9.5

9.5 insufisiensi

8

38.1

47.6 optimal

11

52.4

100.0 Total

21

100.0

3. KADAR VITAMIN D PADA KELOMPOK YANG DIBERIKAN VITAMIN D

Descriptives Kadar Vitamin D

Statistic Std. Error

kadar vitamin d sebelum

intervensi

Mean 31.3524 1.99664

95% Confidence Interval for

Mean

Lower Bound 27.1875

Upper Bound 35.5173

5% Trimmed Mean 31.4721

Median 32.6700

Variance 83.718

Std. Deviation 9.14977

Minimum 13.26

Maximum 47.19

Range 33.93

Interquartile Range 11.06

(8)

Kurtosis -.163 .972

kadar vitamin d sesudah

intervensi

Mean 60.6257 4.63580

Mean

Lower Bound 50.9556

Upper Bound 70.2958

Median 59.9500

Variance 451.303

Minimum 25.58

Maximum 114.46

Range 88.88

Skewness .685 .501

Kurtosis .574 .972

Rerata Kadar Vitamin D

Mean N Std. Deviation Std. Error Mean

Pair 1

intervensi 31.3524 21 9.14977 1.99664

intervensi 60.6257 21 21.24390 4.63580

Uji Statistik T Berpasangan

Paired Differences t df Sig.

(2-Interval of the

Difference

Lower Upper

Pair 1

kadar vitamin d

sebelum

intervensi - kadar

vitamin d sesudah

intervensi

(9)

4. KADAR VITAMIN D PADA KELOMPOK PLASEBO

Kadar Vitamin D Pada Kelompok Plasebo Descriptives

Statistic Std. Error

intervensi

Mean 29.8148 1.64564

Mean

Lower Bound 26.3820

Upper Bound 33.2475

Median 30.5200

Variance 56.871

Minimum 15.68

Maximum 42.60

Range 26.92

Skewness -.183 .501

Kurtosis -.889 .972

intervensi

Mean 31.1810 1.79675

Mean

Lower Bound 27.4330

Upper Bound 34.9289

Median 30.2700

Variance 67.794

Minimum 16.52

Maximum 45.92

Range 29.40

Skewness .297 .501

(10)

Paired Samples Statistics

Mean N Std. Deviation Std. Error Mean

Pair 1

intervensi 29.8148 21 7.54126 1.64564

intervensi 31.1810 21 8.23372 1.79675

Paired Samples Test

Paired Differences t df Sig.

(2-tailed) Mean Std.

Deviation

Std.

Error

Mean

95% Confidence

Interval of the

Difference

Lower Upper

Pair 1

kadar vitamin d

sebelum

intervensi -

kadar vitamin d

sesudah

intervensi

(11)

5. PERBANDINGAN KADAR VITAMIN D

Descriptive Statistics Sebelum Pemberian Vitamin D

N Mean Std.

Deviation

Minimum Maximum Percentiles

25th 50th

(Median)

75th

kadar vitamin

d sebelum

intervensi

42 30.5836 8.31778 13.26 47.19 24.3675 31.9250 36.2100

no

responden 42 1.50 .506 1 2 1.00 1.50 2.00

Uji Test Statisticsa,b

kadar vitamin d sebelum intervensi

Chi-Square .320

df 1

Asymp. Sig. .571

a. Kruskal Wallis Test

b. Grouping Variable: no responden

Descriptive Statistics Sesudah Pemberian Vitamin D

N Mean Std.

Deviation

Minimum Maximum Percentiles

25th 50th

(Median)

75th

kadar vitamin d

sesudah

intervensi

42 45.9033 21.80031 16.52 114.46 29.1300 40.5850 60.6325

(12)

Test Statisticsa,b

kadar vitamin d sesudah intervensi

Chi-Square 22.726

Df 1

Asymp. Sig. .000

a. Kruskal Wallis Test

6. PERBEDAAN ZONA

JUMLAH ZONA TERLIBAT SEBELUM INTERVENSI VIT D PADA KELOMPOK VITAMIN D

Percent

Valid

Dua Zona Terlibat 2 9.5 9.5 9.5

Tiga Zona Terlibat 6 28.6 28.6 38.1

Empat Zona Terlibat 8 38.1 38.1 76.2

Lima Zona Terlibat 2 9.5 9.5 85.7

Enam Zona Terlibat 3 14.3 14.3 100.0

Total 21 100.0 100.0

JUMLAH ZONA TERLIBAT SESUDAH INTERVENSI VIT D PADA KELOMPOK VITAMIN D

Percent

Valid

Satu Zona Terlibat 2 9.5 9.5 9.5

(13)

PRE ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D

polimorfisme gen rvd Total

AA Aa aa

% within jumlah zona terlibat

sebelum intervensi vit d 0.0% 50.0% 50.0% 100.0%

% within polimorfisme gen rvd 100.0% 0.0% 16.7% 14.3%

Total

Count 1 8 12 21

Expected Count 1.0 8.0 12.0 21.0

(14)

POST ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D

AA Aa aa

sesudah intervensi vit d 0.0% 50.0% 50.0% 100.0%

sesudah intervensi vit d 0.0% 0.0% 100.0% 100.0% % within polimorfisme gen rvd 0.0% 0.0% 8.3% 4.8%

Total

Count 1 8 12 21

Expected Count 1.0 8.0 12.0 21.0 % within jumlah zona terlibat

(15)

jumlah zona terlibat sebelum intervensi vit d * luas lesi pre thoraks

luas lesi pre thoraks Total

moderate far advance

jumlah zona

sebelum intervensi vit d 100.0% 0.0% 100.0%

% within luas lesi pre thoraks _0.0% _30.0% _14.3%

Total

Count ₁₁ ₁₀ ₂₁

Expected Count _11.0 _10.0 _21.0

(16)

jumlah zona terlibat sesudah intervensi vit d * luasl lesi post thoraks

luasl lesi post thoraks Total

minimal moderate far advance

jumlah

% within luasl lesi post

thoraks 28.6% 0.0% 0.0% 9.5%

Dua Zona

Terlibat

Count 3 1 1 5

thoraks 42.9% 10.0% 25.0% 23.8%

Tiga Zona

Terlibat

Count 2 5 0 7

thoraks 28.6% 50.0% 0.0% 33.3%

thoraks 0.0% 40.0% 25.0% 23.8%

Lima Zona

Terlibat

Count 0 0 1 1

Expected Count .3 .5 .2 1.0

thoraks 0.0% 0.0% 25.0% 4.8%

Enam Zona

Terlibat

Count 0 0 1 1

(17)

thoraks 0.0% 0.0% 25.0% 4.8%

Total

Count 7 10 4 21

thoraks 100.0% 100.0% 100.0% 100.0%

PADA KELOMPOK PLASEBO

jumlah zona terlibat sebelum intervensi vit d

Percent

Valid

Total 21 100.0 100.0

jumlah zona terlibat sesudah intervensi vit d

Percent

Valid

Bersih 1 4.8 4.8 4.8

(18)

KELOMPOK PLASEBO PADA POLIMORFISME

Crosstab SEBELUM PEMBERIAN PLASEBO

AA Aa aa

(19)

Crosstab SESUDAH PEMBERIAN PLASEBO

AA Aa aa

% within jumlah zona

terlibat sesudah intervensi

vit d

0.0% 0.0% 100.0% 100.0%

% within polimorfisme gen

rvd 0.0% 0.0% 9.1% 4.8%

Satu Zona

Terlibat

Count 0 1 0 1

vit d

0.0% 100.0% 0.0% 100.0%

rvd 0.0% 14.3% 0.0% 4.8%

Dua Zona

Terlibat

Count 2 1 4 7

vit d

28.6% 14.3% 57.1% 100.0%

rvd 66.7% 14.3% 36.4% 33.3%

Tiga Zona

Terlibat

Count 0 1 1 2

Expected Count .3 .7 1.0 2.0

vit d

0.0% 50.0% 50.0% 100.0%

(20)

Empat Zona

Terlibat

Count 1 1 0 2

vit d

50.0% 50.0% 0.0% 100.0%

rvd 33.3% 14.3% 0.0% 9.5%

Lima Zona

Terlibat

Count 0 3 3 6

Expected Count .9 2.0 3.1 6.0

vit d

0.0% 50.0% 50.0% 100.0%

rvd 0.0% 42.9% 27.3% 28.6%

Enam Zona

Terlibat

Count 0 0 2 2

vit d

0.0% 0.0% 100.0% 100.0%

rvd 0.0% 0.0% 18.2% 9.5%

Total

Count 3 7 11 21

vit d

14.3% 33.3% 52.4% 100.0%

(21)

JUMLAH ZONA BERDASARKAN LESI PRE PADA PLASEBO

jumlah zona terlibat sebelum intervensi vit d pada kelompok plasebo * luas lesi pre thoraks Crosstabulation

jumlah zona

terlibat sebelum

(22)

terlibat sebelum

intervensi vit d

0.0% 37.5% 62.5% 100.0%

% within luas lesi pre

thoraks 0.0% 30.0% 50.0% 38.1%

Enam Zona

Terlibat

Count 0 0 3 3

terlibat sebelum

intervensi vit d

0.0% 0.0% 100.0% 100.0%

thoraks 0.0% 0.0% 30.0% 14.3%

Total

Count 1 10 10 21

Expected Count 1.0 10.0 10.0 21.0

terlibat sebelum

intervensi vit d

4.8% 47.6% 47.6% 100.0%

(23)

jumlah zona terlibat sesudah intervensi PLASEBO * luasl lesi post thoraks Crosstabulation

bersih minimal moderate far advance

jumlah zona

terlibat sesudah

intervensi vit d

100.0% 0.0% 0.0% 0.0% 100.0%

thoraks 100.0% 0.0% 0.0% 0.0% 4.8%

Satu Zona

Terlibat

Count 0 1 0 0 1

Expected Count .0 .0 .7 .2 1.0

terlibat sesudah

intervensi vit d

0.0% 100.0% 0.0% 0.0% 100.0%

thoraks 0.0% 100.0% 0.0% 0.0% 4.8%

Dua Zona

Terlibat

Count 0 0 7 0 7

Expected Count .3 .3 4.7 1.7 7.0

terlibat sesudah

intervensi vit d

0.0% 0.0% 100.0% 0.0% 100.0%

thoraks 0.0% 0.0% 50.0% 0.0% 33.3%

Tiga Zona

Terlibat

Count 0 0 2 0 2

Expected Count .1 .1 1.3 .5 2.0

terlibat sesudah

intervensi vit d

0.0% 0.0% 100.0% 0.0% 100.0%

thoraks 0.0% 0.0% 14.3% 0.0% 9.5%

Empat Zona

Terlibat

Count 0 0 2 0 2

terlibat sesudah

intervensi vit d

(24)

thoraks 0.0% 0.0% 14.3% 0.0% 9.5%

Lima Zona

Terlibat

Count 0 0 2 4 6

Expected Count .3 .3 4.0 1.4 6.0

terlibat sesudah

intervensi vit d

0.0% 0.0% 33.3% 66.7% 100.0%

thoraks 0.0% 0.0% 14.3% 80.0% 28.6%

Enam Zona

Terlibat

Count 0 0 1 1 2

terlibat sesudah

intervensi vit d

0.0% 0.0% 50.0% 50.0% 100.0%

thoraks 0.0% 0.0% 7.1% 20.0% 9.5%

Total

Count 1 1 14 5 21

Expected Count 1.0 1.0 14.0 5.0 21.0

terlibat sesudah

intervensi vit d

4.8% 4.8% 66.7% 23.8% 100.0%

(25)

UJI PERBEDAAN HASIL FOTO THORAKS PADA KELOMPOK VITAMIN D

Interval of the

Difference

jumlah zona terlibat sebelum

intervensi vit d 3.90 21 1.179 .257

jumlah zona terlibat sesudah

intervensi vit d 3.05 21 1.244 .271

Uji Beda keterlibatan zona JUMLAH ZONA TERLIBAT

SEBELUM INTERVENSI VIT D PADA KELOMPOK VITAMIN D

95% Confidence Interval

of the Difference

(26)

7. PERBAIKAN FOTO TORAKS

Crosstab kelompok vit d sesudah

perbaikan Total

tidak ada

% within perbaikan 0.0% 10.0% 0.0% 4.8%

% of Total 0.0% 4.8% 0.0% 4.8%

(27)

Terlibat Expected Count .3 .5 .2 1.0

% within perbaikan 100.0% 100.0% 100.0% 100.0%

% of Total 33.3% 47.6% 19.0% 100.0%

Crosstab pada kelompok plasebo sesudah

perbaikan Total

tidak ada

intervensi vit

d

Bersih

Count 0 0 0 1 1

Expected Count .6 .1 .2 .0 1.0

sesudah intervensi vit d 0.0% 0.0% 0.0% 100.0% 100.0%

% within perbaikan 30.8% 33.3% 50.0% 0.0% 33.3%

% of Total 19.0% 4.8% 9.5% 0.0% 33.3%

(28)

Terlibat Expected Count 1.2 .3 .4 .1 2.0

% of Total 0.0% 0.0% 9.5% 0.0% 9.5%

Empat

Zona

Terlibat

Count 1 1 0 0 2

Expected Count 1.2 .3 .4 .1 2.0

% of Total 4.8% 4.8% 0.0% 0.0% 9.5%

Lima Zona

Terlibat

Count 5 1 0 0 6

Expected Count 3.7 .9 1.1 .3 6.0

% of Total 23.8% 4.8% 0.0% 0.0% 28.6%

Enam Zona

Terlibat

Count 2 0 0 0 2

Expected Count 1.2 .3 .4 .1 2.0

% of Total 9.5% 0.0% 0.0% 0.0% 9.5%

Total

Count 13 3 4 1 21

Expected Count 13.0 3.0 4.0 1.0 21.0

(29)

8. PERBEDAAN JUMLH ZONA BERDASARKAN POLIMORFISME

JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D

AA Aa aa

terlibat sebelum intervensi

vit d

0.0% 50.0% 50.0% 100.0%

rvd 0.0% 12.5% 8.3% 9.5%

vit d

0.0% 16.7% 83.3% 100.0%

rvd 0.0% 12.5% 41.7% 28.6%

vit d

0.0% 50.0% 50.0% 100.0%

rvd 0.0% 50.0% 33.3% 38.1%

vit d

0.0% 100.0% 0.0% 100.0%

rvd 0.0% 25.0% 0.0% 9.5%

(30)

Enam

Zona

Terlibat

Count 1 0 2 3

vit d

33.3% 0.0% 66.7% 100.0%

rvd 100.0% 0.0% 16.7% 14.3%

% of Total 4.8% 0.0% 9.5% 14.3%

Total

Count 1 8 12 21

vit d

4.8% 38.1% 57.1% 100.0%

rvd 100.0% 100.0% 100.0% 100.0%

% of Total 4.8% 38.1% 57.1% 100.0%

JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D

AA Aa aa

(31)

% of Total 4.8% 38.1% 57.1% 100.0%

PADA KELOMPOK PLASEBO

SEBELUM PADA KELOMPOK PLASEBO

AA Aa aa

terlibat sebelum

intervensi vit d

0.0% 100.0% 0.0% 100.0%

% within polimorfisme

(32)

terlibat sebelum

intervensi vit d

20.0% 0.0% 80.0% 100.0%

gen rvd 33.3% 0.0% 36.4% 23.8%

terlibat sebelum

intervensi vit d

0.0% 50.0% 50.0% 100.0%

gen rvd 0.0% 14.3% 9.1% 9.5%

terlibat sebelum

intervensi vit d

100.0% 0.0% 0.0% 100.0%

gen rvd 66.7% 0.0% 0.0% 9.5%

terlibat sebelum

intervensi vit d

0.0% 50.0% 50.0% 100.0%

gen rvd 0.0% 57.1% 36.4% 38.1%

terlibat sebelum

intervensi vit d

0.0% 33.3% 66.7% 100.0%

(33)

% of Total 0.0% 4.8% 9.5% 14.3%

Total

Count 3 7 11 21

terlibat sebelum

intervensi vit d

14.3% 33.3% 52.4% 100.0%

gen rvd 100.0% 100.0% 100.0% 100.0%

% of Total 14.3% 33.3% 52.4% 100.0%

SEBELUM PADA KELOMPOK PLASEBO

AA Aa aa

vit d

0.0% 0.0% 100.0% 100.0%

rvd 0.0% 0.0% 18.2% 9.5%

vit d

0.0% 100.0% 0.0% 100.0%

rvd 0.0% 14.3% 0.0% 4.8%

vit d

33.3% 16.7% 50.0% 100.0%

rvd 66.7% 14.3% 27.3% 28.6%

(34)

Tiga Zona

Terlibat

Count 0 1 1 2

vit d

0.0% 50.0% 50.0% 100.0%

rvd 0.0% 14.3% 9.1% 9.5%

vit d

50.0% 50.0% 0.0% 100.0%

rvd 33.3% 14.3% 0.0% 9.5%

vit d

0.0% 50.0% 50.0% 100.0%

rvd 0.0% 42.9% 27.3% 28.6%

vit d

0.0% 0.0% 100.0% 100.0%

rvd 0.0% 0.0% 18.2% 9.5%

% of Total 0.0% 0.0% 9.5% 9.5%

Total

Count 3 7 11 21

vit d

(35)

rvd 100.0% 100.0% 100.0% 100.0%

% of Total 14.3% 33.3% 52.4% 100.0%

9. PERBAIKAN TERHADAP POLIMORFISME

polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation

moderate far advance

polimorfisme gen rvd AA

Count 0 1 1

rvd 0.0% 100.0% 100.0%

thoraks 0.0% 10.0% 4.8%

% of Total 0.0% 4.8% 4.8%

Aa

Count 5 3 8

rvd 62.5% 37.5% 100.0%

thoraks 45.5% 30.0% 38.1%

% of Total 23.8% 14.3% 38.1%

aa

Count 6 6 12

rvd 50.0% 50.0% 100.0%

thoraks 54.5% 60.0% 57.1%

% of Total 28.6% 28.6% 57.1%

Total

Count 11 10 21

rvd 52.4% 47.6% 100.0%

thoraks 100.0% 100.0% 100.0%

% of Total 52.4% 47.6% 100.0%

(36)

Count 0 1 0 1

rvd 0.0% 100.0% 0.0% 100.0%

thoraks 0.0% 10.0% 0.0% 4.8%

% of Total 0.0% 4.8% 0.0% 4.8%

Aa

Count 2 5 1 8

rvd 25.0% 62.5% 12.5% 100.0%

thoraks 28.6% 50.0% 25.0% 38.1%

% of Total 9.5% 23.8% 4.8% 38.1%

aa

Count 5 4 3 12

rvd 41.7% 33.3% 25.0% 100.0%

thoraks 71.4% 40.0% 75.0% 57.1%

% of Total 23.8% 19.0% 14.3% 57.1%

Total

Count 7 10 4 21

rvd 33.3% 47.6% 19.0% 100.0%

thoraks 100.0% 100.0% 100.0% 100.0%

% of Total 33.3% 47.6% 19.0% 100.0%

polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation

Count 0 2 1 3

rvd 0.0% 66.7% 33.3% 100.0%

% within luas lesi pre thoraks 0.0% 20.0% 10.0% 14.3%

(37)

Aa

Count 1 3 3 7

rvd 14.3% 42.9% 42.9% 100.0%

% of Total 4.8% 14.3% 14.3% 33.3%

aa

Count 0 5 6 11

rvd 0.0% 45.5% 54.5% 100.0%

% of Total 0.0% 23.8% 28.6% 52.4%

Total

Count 1 10 10 21

rvd 4.8% 47.6% 47.6% 100.0%

% of Total 4.8% 47.6% 47.6% 100.0%

polimorfisme gen rvd * luasl lesi post thoraks Crosstabulation

bersih minimal moderate far advance

polimorfisme

gen rvd

AA

Count 0 0 3 0 3

% within polimorfisme gen rvd 0.0% 0.0% 100.0% 0.0% 100.0%

thoraks 0.0% 0.0% 21.4% 0.0% 14.3%

% of Total 0.0% 0.0% 14.3% 0.0% 14.3%

Aa

Count 0 1 4 2 7

thoraks 0.0% 100.0% 28.6% 40.0% 33.3%

% of Total 0.0% 4.8% 19.0% 9.5% 33.3%

aa

Count 1 0 7 3 11

thoraks 100.0% 0.0% 50.0% 60.0% 52.4%

% of Total 4.8% 0.0% 33.3% 14.3% 52.4%

(38)

thoraks 100.0% 100.0% 100.0% 100.0% 100.0%

% of Total 4.8% 4.8% 66.7% 23.8% 100.0%

10. HUBUNGAN FOTO THORAKS DENGAN POLIMORFISME

perbaikan pada kelompok yang diberikan vitamin D * Polimorfis Crosstabulation

Polimorfis Total

AA+Aa aa

perbaikan pada kedua

kelompok

tidak ada perbaikan foto

thorax

Count 3 4 7

Expected Count 3.0 4.0 7.0

ada perbaikan foto thorax

Count 6 8 14

Total

Count 9 12 21

Chi-Square Tests

Value df Asymp. Sig.

(2-sided)

Exact Sig.

(2-sided)

Exact Sig.

(1-sided)

Pearson Chi-Square .000a 1 1.000

Continuity Correctionb .000 1 1.000

Likelihood Ratio .000 1 1.000

Fisher's Exact Test 1.000 .681

Linear-by-Linear Association .000 1 1.000

N of Valid Cases 21

a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.00.

(39)

perbaikan pada kedua kelompok * Polimorfis Crosstabulation

Polimorfis Total

AA+Aa aa

perbaikan pada kedua

kelompok

tidak ada perbaikan foto

thorax

Count 5 8 13

ada perbaikan foto thorax

Count 5 3 8

Total

Count 10 11 21

Chi-Square Tests

Value df Asymp. Sig.

(2-sided)

Exact Sig.

(2-sided)

Exact Sig.

(1-sided)

Pearson Chi-Square 1.147a 1 .284

Continuity Correctionb .386 1 .534

Likelihood Ratio 1.156 1 .282

Fisher's Exact Test .387 .268

Linear-by-Linear Association 1.093 1 .296

N of Valid Cases 21

a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.81.

(40)

(41)