ISI BERITA
Merujuk pedhal
tersebd
dial,as,
bersarna ini dengnn hormat disampaikan
haltal
sbb:
1.
Berdasarkan
data lGntor
W-|o
Wilayah Timur
Mediteriania,
deuasa
ini
jumlah
penduduk
Yaman yang berkisar
19,7
iuta
orang
llang
s€kitar
71c/o diantananya
tinggal
di
daerah
pedesaan
dan
tkqkat
buta
hurufnya relatif
tinggi
dengan
prosentase
55,7o/o.
Yaman
juga
digolongkan
ssbagai negara
ber.endapatan
perkapita
rendah,
dengan
GDP
nyra
sekitar
tJSi$
659.00.
EXsisi
ldin,
Yaman
membelanjakan
sekilar
5,5016dafi
GDP nya uniuk
sektor kesehatan (pada tahun
2003) dengan total behnia kesetratan per
kepatarrya
mencapai
US$
32.00
2.
Befanja
sektor
srm$al
ori'rarte
expnditure
Udang kesehatan
dari
prosentase total
pengeluaran
kcs€hdan
diperkirakan
befiisar 59%
da
tdrun
2003-
Fasilitas
kesehatan berupa rumah sakit (baik milik
pemerintdr
maupun snasila)
tedapat
di
sejurrilah kota-kota
besar
(sepedi
Sana'a,
Aden
dan
Hodeklah)
dan
fasilitas
kesehatan
dibawah rumah
sakit
seperti poliklinik
dan
unil
kesehatan umumnya
tersedia sampai
dacrah pcdc:laar.
Namun demikian, pelayanan
saklor
kesehatan
tidaklah gratis
-
pasktn harus
rcmbalar
baya
konsultasi
doktemya
dan
biaya untuk
mendapatkan obat-obatannya dengan
harga
nnfl(
up
sekitar
109o (kecuali untuk
sejunlah
obat-obatan
yang mcndaeattan
subsldi
yang dibcrikan kcpada
pasien
dengnn gratis).
3.
Indusfi fannasi lokel (yang beriumbh 10
pabrik) harrya rnampu
rnemenuhi
kebutuhan
donestik sekitar
1O%
*ia
dan
sebbifnya
dlimpor
dad
negana-negaftl
Arab,
produsen
fannasi
di
Eropa
dan negr+negara Asia
Selatan
serta
Asia
Tenggara
meldui
perusahaan importir fannasi
Yaman.
Terdapat hal menarik bahwa
produlr
fanmsi yang diinpor dari
negar&negara
Asia
(klrususnya
lrdia
dan
Pakistan) harganya
relatif lebih
murah daripada
yang
diimpor
dad
negaftFnegara
diluar lndia dan
Pakisilan.
4-
Gambaran
urnrm
produk-produk
fannasi
di
Yeman ditandai dengan
masih
te6atasnya
ketersediaan poduk-produk
Fannasi
di unit+nit
kesehatar umum; pada
toko
penjualan
produk-produk farmasU
apotk $rasta,
harga
iual
obatan-batan
bermerak relatif mahal
dan
obd-obatan gcncdc
bervariai
harganya,
mubi
dari
sangat murah sampai
dengnn
rnahal;
serta,
perEpbatan
penyakit rnenggunakan
obat-obatan generic relatif
tefangkau
hargarrya
dibanrlingkan menggunakan
obat-obatan
bermerek
5.
Secara umurn, pada wilayeh
yatg
dinaungi
oleh WHO Easfem lilditenanean
Rqion
ditandai dengpn kenyataan bahwa masyalakat terpaksa
harus
membayar
biaya kesehatan/ pengobatannla
jika rnendataqi
fasilitas kesehatan swasila yang
kadangkala harganya
mahd dan
kondisi
hi
memunculkan
desakan
kuat
bagi
pemerintah untuk campur tangnry' memperbaiki hebijakan farmasi nasionafnya dan
kebijakan pcrrcntuan harya yang
cbktif-6.
Bagi prcduk-produk
f;annasi
impor sebelum rnemperoleh
lfrn
bercdar di Yaman, pihak
berwenang
di
Yaman
(Supenn
Boad for
Drugs ancl
tyledtcall
Applianes)
mengirimken
lim
pemeriksanya rneniniau cara pembuatan
obatobatan/
on
the
spot
di
pabrik-pabrik
farmasinla untuk
memastikan
bahwa
poduksi
obatobatannya
sudah
mernont
hi
standar
(di
Indonesia,
dikenal dengen
pemberien
fabel
cara
pemb,uatan
obat yang baiU CPOB).
7.
Dilihat
dad
aspek
ketefirngkauei
haqe
obat-obaten
bagi
masyaraftat
di
Yaman,
diukur dari jumlah hari heria dan dikaitkan dengan perolehan gnii terendah pegawai
pennrintah
unsUlled
yang akan
digunakan
untuk
membayar
biaya
pengobatan
2t12
9.
suatu penyakiU
aqr{e
cnn&fun
ataup{.tn
pengobdan
selama sebulan bagi kondisi/
penyekil
yang
kmniU
drrcnic
@trtlior,
dengan gaii terendah
pegmai
pemedntah di
tahr.rn
2006
addah
sebesar
555
Yemena
nlBls
(setara
US$
2-81)
per
harinya.
Dengan
denikian,
untuk
mcmpcrdotr obet
gorcric temurah
di toko farrnasi/ apotilc
akan
nrrmkan
tfaya
krang
dad
gafr
pernenrrya
yang sebeser 555 Yemeni
riyals,
kecuali
untuk
pembelian amitriptyline
(deprassion),
captetil
(hypertension),
metfonrin
(diabetee)
dan carbrrp2sp*
(cptlopry)
yang
msing-masing
membutuhkan Uaya 1,8i 1,4:1,4;
d*r,
1,1
dari upah
habnnya.
Sementara biaya pengobatan
menggrurnakan
obat-obatan bernerck adalah 2
sampai
12 lebih
mdral
harganya bilarnana
rrnggunaken
obgtobatan gernric.
Pengobatan
menggunakan
obd.obdan
bcr?ncrek umumrrya
nrcrbutuhl
n Uaya lebih dari 3 hari
upah
harian
peganrai
penFfitah,
dengan
bfrya
tertinggi
s:ld
merryembuhkan
penyakit
peptic ulcer
mernakai ranitfdine
(5,8 had
dad
upah
hadannya),
menyembuhkan
hlperlension
manggunaltan
@Fn
(5,4 hati dari upeh harbnnya)
dan menyernbuhkan artbdtis nnnggundran didofenac (5 hari dad upah hariannya).
Pembefian/
pengadan
obd$atan
gcnedc dilakukan
deh
ffp
lhtional
Prqnmfor
fil/eidial
Sr/npry
dengm har3n
Zffi
lGUh
rcnd*t
dathada harga
referensi
intemasional.
Namm denikbn, kofipornn
hargn
pada
toko-toko penjual
obat-obatarV apotik milik
suvasta
urrrJrnnya tcrdapet
dlldd
cunuffiive
nnr*-up
sebesar
57,4Vo
baak
terhadap
obat+batan lokal
maupun irxpor
dan
baik terfiadap
obat-obatan gwredc
nEupun bermerek. Angka
57,4%
tersebuil
ferdiri
dari
ma*
up
pada
distributor sabcsar l()96 dan
nn*
up
peda
loketoko
obet-obetan/ apotik esbeser
20%.
Pengamatanl
G€trn
l(BRl
10. Dewasa
ini
juntah
toko penjual obatobatan/ apotik di selunrh
Yanun
berkisar
10O0
buah dan
iumlah/
jenis oba{obatm yang
sudah
ierdallar pada
Kementerian
Kesehatan
oq.
Snpnanr
Mrd
for
&
lgs
atd
*|edicall
Afliarws
berkisar
16.000
buah.
ll.Obatobatan
yang
diinrpor
bcrasal dari
rtegar*-nogara
Arab
(Suriah,
Mcsir,
Arab
Saudi,
Yodania
dan
PEA), negara-rng€fia Eropa (lnggeris,
Peranciq
Jennan dan
Turki) dan negara-negara
Ash
(C}ilna,
Korta
Selatan, India,
Pakisilan.
Malalaia dan
sebagian
kecil
dari
Indonecia). Produk
farmasil
obat-obatan
dari
lndonesia yang
sudah
mag.rlr
dan
beterhr
di Yaman
dixodultsi
obfi
PT-
Intedat
(dengan agonnya
Dadsih
G€rnral
Trading
d[
Sana'a),
PT.
Carung
Indah Abad,
-
hethl
ndicine
industryl
jarrujam.en
(dengan
agsmp
AFMa?br
phanna
dli
Sana'a). PT. Dragon
Pnma
Farna dan PT.
Deirya
Varia yang
saat
ini
sedang melakukan peniaiakan
lapangan.
Tidak rnenutlp
falde
d
hpangan betrua
ada
jugn obat-obdan/
farmasi
produk Indonesia yang
masr*
melalui
jalurli@k
resni
12.
Obat-obatm/ farrnasi yeng umumnya dipakai di Yaman untuk rnengobatil mengatasi
penyakit
hipcrtcrld,
infiuenza,
bsiut
dan
jed+ienis
pernfalcit
lainnya
yarug
bersitat
epiderilc
Selain
obetdaten/
fannasi yang
nerniliki
potensi pasar, alat kesehatan
fainnya
seperti iarum strntik,
det-alat
kontrascpi, debsftop,
alat
tcni
darah (baik
yang konvensbnal maupun
dbttal),
tetqDet
lidr
pasien, kursi tpda,
alel
penyangga
lraki,
tangan dan kaki
palsu
juga mempunyai proqpek yang
cerah.
13.
Saat bertemu
dengm
pcrusahaan importir
fernasi di
Yaman. kualitas obatobatan/
14.
Terlampir
disanpaikan
ddar
pcrulaltaart
ifTrpoftr
famrai
d
Yaman dan artikel dari
WF|O
&sfem
,ifclcfrforfiarcn
Wn
mcr4rcnai
q(cnpn:
ttledieirc
Nes,
avaih ffifty,
atrorlaltifity
and
prtn
@marlnellls'-Demikian
disanpaikan,
alas
pcrfidan rhn
brfr$rnanya
diucapbn
tedma kasih.
Sana'a.
0E
Maret 2009
4112
1.
Pharmaceudcals, Healtlrcare and
He6al
Producti
NationalTrading
Company Ltd.
Natco,
Yemen
Head
Office: Djibouti
Str., ln
front of
Pol-Seorrity
BuiHing;
Sana'a
Tel/Fax:
(967-t@l5@;
Fax:
{96i1-1H4.754115-274L18-274r69,
P,O. Box:
1182
1105, 1108
We
b
site: www-
natco-ye
men.corn;
e-mail: natbnal@
natco.ciom.ye
Arraafah
Corporatbn,
Yemen
Leading Yemeni
lmport€r
and Agent
of
several
leadi,ngmmpanies in
medical
field
Head Otticn:
Ali Abdulmughni Street,
Behind
Taj Sheba
ll'otel,
Sana'a -
Yemen
Tef
:
(957-1)
273W-273988;
Fax:
1962 -L12723U,
P.O.
Box:
109OWeb
site:
urwtry.arraafah.bir;
e-mail: arraafah@y.netye
Ala'bed
Medical
suppliesCo.
Ltd., Yernen
Leading Yemeni Company Specialized
in
lmport and
Marketing
of
Pharmaceuticals
and
medicines.
Head
Office:
Sana'a -
Yemen.
Te t :
(967-1)
47 287 5I
617;
Fax: (967-1)47
2874,
rc
Box:
8286
We bs ite : unrrvu.a la
bedpha
rma.com;
e- mail:
info@a
labedpharma.co
m
AFFurqan
Trading,
Yemen
Leading
Yemeni
Corporation
Specialized
in
lmport
and Marketing
of
Pharmaceuti,cals and
medicines.
Head
Office:
Sana'a
-Yemen.
Tef
: (957-1)47
2883
|
a I5; Fax:
(967- 1)47 28t82,Po
Box :8285
E-mail: info@atfu
rqanpharma.com
Al-Ghazali
For
Trade
&
Medicines
,
Yemen
Head
Office;22nd
May Str.,
Sana'a.
TellFax
(967-11675280/81;
Fax:
(967-1167s277,
P.o.
Box: 2069
Web
Site:
wvnn.ghazalipharma.com;
e-mail:
f.ghazali@yernen.net-ye
MIASS
Trading Center
for
Medicines & Generaf Agencies
,Yemen
Head
Office: 45
St,
in
front of Af-(ohali
Tower,
Sana'a -
Yemen
Tef;
(96-l-1l6l440t;
Fax;(967-1f
6t4d,ffi,
POBox
:2O299
E-mail: miasspharma@yemen-net.ye; miassphanna@yahoo-com
tnffii
ffsassy
etutW,
fujMr,
bfu(
79mtH&,fuPb'Ycrrwr
Td:
(571)
A721AQ7211; htt:
(67-4
qZZ2tZ;E;mil:
tu6at
@/.,reLF7.
A'alam
Al-Dawa
Co.
ttd.,
Yemen
Head
Office:
Al-Shera'ee Str,
Behird
C.enbral
Bank
of
Yemen Building,
Sana'a.
Tef/Fax (967-U271831;
Far
(967-11272635,
P.O.
Bor
4242
Web
Site:
wnnr-aal-dawa.com;
e-maih
aal-dawa@y.netye; aaldawa@yemen.net.ye
8.
Amir Aldin
Co. For
Trading
& Agencbs
Ltd.,
Yemen
Pharmaceuticals and
medirzl
appliances
Head Offrce:
Altahreer-Saif
ben
thi
yaaen
stree$
Sana'a
Te |
:
( s67 - I ln
1ffi3
/
275395;
Far: l96t
-r127?t330,
P.o.
Box : 8432
Website: wmry.amiraldinco.com; e-mail: info@arniraldinco.com
9.
Al-Marwan
Medical
Corporation,
Yemen
Head
Office:
Al{aser
Str, Behind
Taj Sheba
Hotel,
Sana'a -
Yemen
Te
l/Fax:
(%f
-tl29Tn1;
Mobile:
{967Vn
LLT6L7,
P.O. Box:
4323
E-ma
il:
marwan80@yemen.net.ye
10.
ARJA'A TRADING,
Yemen
Head
Office:
Taiz
Str.,
Sana'a -
Yemen.
Tef
:
(967-1)633677 -
Fax:{96'7-l)633674,
P.O. Box:
2685
We
b
s ite :www.arjaagrou
p.com;
e-mail:
aria a @ye rnen.net.ye
11.
Al-Razi
Pharmaeutical
Center, Yemen
ALRAZI
is an importing
&
markeUlg company
with
long experiences,
import
&
distribute
pharmaceutical products
&
Medlcal appliances
,
Baby Food
and
Veterinary medicine
in
Yemen
market.
Head
Offrce: Seiun,
Hadramout
-
Yemen.
Tel:
(95-f-5)4O3803; Fax:
(967-11403336,
P.O-Bor
9il)2
E-mail:
ZUBAIDI €!Y.NET.YE12.
Bilquis Drugstores, Yemen
Bilquis Drugstores
are
a
private company importlng pharmaceuticals,
foodstuff
and
baby
mifk and
fmd to
Yemen market
for
more
than
30 years. The company represents
many
world
companies
that
produce rnucft rnercftandise.
Head
Office:
Eehind
Central
Bank
of Yerneo
Sanab
- Yenren.
Tel: (967-1)272274 -278136
- Fax:
{95-l-1l27$tq
P.O.Bor
305
Website: www.bilguis-ye.com; e-mail: Bilquis.d.s@y,netye
lndonedan Embrcy
eift W,
hjAffir,
h
tu
l*tft
t&
*Be
- feaw,
Td:
(%7-t)
427214427211;hx: (fi7-l)
427214 Eraril:inM@t'.ne.re
6112
&Srx**ctm*
grrie*s,
sv**taxLt*ttuy.
mff*r'c$mh*
*it.v
erl# pri*;*
jiil
S,: ei i ;r. i ;t,".: ;:'.: i f: 13 :" i'li"tt
if
*
f
Rapidly rising costs of hcalth care and high medicine prices arc
a grorving conc€rn *'orldwlle, especiallv in d*<{oping
counritl
w'hr:re patierrts oftcn havc ro pa;, rhe 6rll price of medicincs. This
bricf rcport about mudicine prkes and availzbiliqv in l'etnen is onc of a seritx of papcrs strrnmariring the tcsults nf national mcdicine
pricc and arailabilitv suncys carried our around the globc using
a standard survry m.thodology devdogd hy the $9orld Hr>alth
Organization
{\fHO)
and H<alth Acrion lnrcrnational (}IAD.It
trs<* a group of 3() mcdicines, widr prt-tet dosage fornrs, strengths,
and pack sircs that are le'lcr:ot co thc glohcl bunlcn of disease,
pltrs st'lected medicins of nati rnal imporance, TheYcmcn sunev
rras undcrtaken in rnid-2006 bv thc Supremt Board for Drugs and
J\'ledicat Appliances (drug regulatorv authoriry).
rFidrin l'emen:
.
Thc, availabiligv of mcdicines in the public srxtor outlets wasvcry l,:w
.
In prirate pharmacies, the prices of originator brand products rverc gencrally ver.v higlr wherras prices of generkcquivalents varied from vcry cheap to high.
.
Trtattnents with lr*v pric<d gcnencsrcrc
re,larivelvaffordable compared to originator brands.
Generelly, across
the
WHO
Fascernllltditerrantln
Rr.gion,a
sinrilar picrurccrncrgr::
rcasonebly cffic,icnt public c,xtorprocuremcnt, people having to pay for their own tncdicincs in thc
prirate i(€tor; ofren at high and froquentlv unafiondablc' priax; and
thc need firr str<,ngct governmcnt action to intrtrdtre or imprcvc
nati,rnal rncdicinrs policies alrd
efrrtire
pricing polici<*.ir,:i:fliir?
r:riif{i.if,iirls}x}ri::#
,*fxi aii,i}ii*i}ii!t-v
${{{\i€:.v-Yemen has a population of approx. I 9.7 million inhabltants, 7196
of rvhom livc in rural arrrs. The illite,racy rate is high and reachs
about 55.79.r.
ltmcrr
is a lor+'-incomc countr;vwith
per cagiraL WI
io/tl.tl.
M<lijnc pri*s:a ncw appwch to m636s6mgnr" (-rncs,
\forld tteelrh Orsuttarion, 7Oo3. Ar'.rth\|. fFm hnpr//*lnthdwb.o€,/
ln&li.ineprii'e5
t \ilHOiH.f. llc&drc pnrs, atuibbrtry ajfui&rk1' dtd prie .e,ipo4ftt.
i
''ariAa rylw r d{ n2dittnt 2ttzc xttr4 radatt*at i* nhacl twilrta ol d:c Wi,li
lh.alth
Qrytwrt*
fnlaa M&tolvnan Rtla*, (ldru, Vorlil I lcrhh Orgrniarion Frsiond Ofhcc lbr rhr
lxwn
Medimnm, ?ff)3 (inpre)-@)H,tlg#:ftL*
Rcgbnrl OftiGG fof thr E5rlrn fqfttcrr.ncrn
*sr}tf3{}ffi#nts
T;rliie
i..
i.".::',. -i ';'f', '::rjit-l.ijProcurefitsrt
Price
r'
-ilr
ifi".:i:
i:i.u:r..'i-'fijltr
iii:.r
lAvailabilrty
ri
Vgrosr
domcrk
product (CDP) of US$ (r59. Yemcn sprcnt 5.5oloof irs GDP on
hahh
in 2003 with a roral hcalth txpendirure pcrcapis,rf US$
32.
Private c'xpenditure on health as a percetrtEl",r[toml expcnditurc on hcalth rvas <stimaced to bc 5996 in 2003.
ln
genczal hcalth sen'icet (either public or prirat€) ere mainly found
in
major cities,ddrou$r
primary trealth .are centres/units andpolyclinics are scattered throughout the w'holc countrv, including
$ome nlral areas, Putrlk hcalth sen'ice.s arc not fuc; the paticnt pap
a precription
ftr
and the (a-store cost of mcdicincs with a I()Yomark-up (trcept for cenain sub,$idibd mrdicines which are given
for free) and thc cost ofany diagnostic tests, as n.rdcd. The local
pharmac<utkai industrv coven appr<rxioretely
l0%
of
thetool
pharmxeutical markct; most medicin,:s are imponed vie Prirate
se(tor agcDrs. A total of J5 etsential rledicinrs rverc samPled: 27 frorn thc
WHO/HAI
corc tist arxl 8 strpplcnrentary nredicine*. A toral of 20 public s,rtor outlcts and 20 private phamraci<s wertincludod in dle curv'ey in the capital Sana'a and
tle
majn citicsof
three other populated govcrnorat€s: Aden, Taiz and Hodeidah. In
oach cit)', one principal public generat hospital' four public
hakh
ccntres and 6ve
pri'atc
pharmaci:s wcre sampled (oe Tablc 1).Thc prccuremetrt prices vlerc obtained from the Natirtnal Progtanr
for Medical Supply
F y+*
l*
-ctteti $ !'i'*"f
i:' ri i: r.? i *
f*
F":: Et';i*
li
lb€
WHO/HAI
survey rnethodologv prcscntsprics
as medianpricc ratios (MPR). Thc MPR is cdculatod bv dividing thc l rcal
prke b.7 dre intcrnationd rcfercne price {convcrtxl
into
krcalcrrrrr'ncy). An MPR of
I
mans rhe local price is cquivalcnt to thcrcfenrncc price, whercas an MPR of2 m.:ans the lmal pricc is twicc the refergrrr prke. The inrcrnatio.ml refcrcncc prkrs used
6r
thissuft-cy,*cre takcn from the 2005 Man4lement Sciencr= for Hcalth (I4SH) Inrcrnational
Dng
Price Indicator Guidc (nrdianprkr:
of
high
quality multi-source medicines offercdto
dcve.lopingcountri$ by different suppliets). Use o[ referencc
prics
facilitatcsintemationat comparisons.
i i1{.,* v l.:rti:'t;rf ir: i'+ i: f, fi
trciirrgl*
Corrntrt
sprrilir
facrors, ruch as pncing polkicrnnla*.a
si'ts,competition, national economic and othcr facrors. ma)'inflrrncc priccs.
Rrr the
purposcsof
thetc
sun-eysin
a
low-incr>medcvcloping countrif an MPR of
les
rhan r:r cqr.urlto
I
for publics*tor
procurcm€ntpric6
and public $ertor pattent prkcs isconsidcred trr iodicate a-ceptahlc (not scrssivc) prices.
.4.1"itt vi-i;i i.itl ii;ir
Affordabilitv is calculetcd ss the numbcr
ot&p
tlre lornst paidunrkillcd gaveutmxnt worker would hare
ro
workto
pay for atRatmcnt coursc for en acuc condition or one mDntht tteatmcnt f,lr a chronic condition. At the time of thc surtc''. the
lowct
paidYcmeni government
wo*er
carncd 555 Yemcni riyele fYER)(US$ 2.81) per da.v. Owing
to
the
limited availabilityof
themedicincs sur-gvcd, it rxas possible ro calculatc affordabilir'' in the
prrblic sector
for
onlvthre
conditionr,witt
dl
three medicirxscosting le$s than half a dat's.,r.agc.
O'-crall
in
tlre
privaterctail
plurmacies a Ycmeni workcr,if
purclrasing l,>w<st priced gencrics, would gencrally necd less then
,,ncdayt wagefor rhesandard tnatmentsanalped foraffordabilitv,
cxccpt
for
anritripqvline (deprcssion), ceptopril (hvpertcnsion),mctforn'rin (diabettx) and carbamanr:pinc (epilepsy) wherc 1.8,
1 .4, 1.4 and
LI
days wagcs arc rcquirct, rc'spcttivd,v Figurcl).
Thc r-ost o[ standard treatmeo$ wirb originaror brands were 2 toI 2 tinres greatcr than the cost when usingi lowesr priccd gcnrric
cquivalents. Treatmc-nts r+'ith originator brandc thendore geoo"elly
cost more than 3
dayi
wages. The most e{rcnsirrc trcatm€ntsr+'l'rcn usiug originator bralds included thc trcatmc'nt rrf peptk
cdctr rcith ranitidinc, 5.8 deyt' wages; tftirtfilcnt ,rf hyperuension
rvith captopril, 5.4 de,v's wages; and trrathrent
of
anhriris with dicloftnac, 5 dalr' rvagcs.Pelic
ukt
tta*otaaitEln
r
m€tto.dnHypctt**n
Drpcssiffic+loFrl
rrtriltyfEG
F.
;3-l
ozl i1:
ffi&fu.fi
13
*i:ii*: s':.jtt!t-
pricsJii
The data on public scrdor procuremenr priccs wcre lirnitcd as
tcndcr price information was available
for
only six medicincs(all generics). Due
to
the low availabilityof
medicincsin
thc publicsctor,
therc waslitde
dae
6rr calculating ptice ratiosfor
pricestbar
paticntspry in
ptrblicsctor
health facilities,On avr.ra€le, generic oredicitrcs werc purchasd b-v the National
Prograrn fnr }ledi<al Sapply ar 2O*o lower pricc (nrcdian ,\lPR =
0.79) than intcmational refcrencc
pricc
{Table 2). This sLrggicststlur
tlw Natinnal Progranr for Medical Supply is cfficicnt lvhcn procuring medicins. although it is dilEcult to iudgt dre cflicicncyof
public procurementof
pharmaccuticalsin
Ycmen bascd orrsuch limited. dara- Likcwise, patient priccs
in
thc public sectorwme gcnerally acceptablc (ncdian
l.{PR l-09
for lowcst pricttlgcrericr). Howtlcr, orling to poor mcdicinc arzilability. data for
onl,v sir medkines could
te
includd in thc analvsis (Table ?) andir was not possiblc ro ass6s tbe diference hct*een public sector
procurrmrntpricts and
paticntprks
(i.e. puhlk scctor mark-up).Pr.:l>i
ir:
sri{:i{:}i
*t.+i!;ihi$iir
The
results shc,t'cdoverdl public
scctor median arailability ,rfonly 5%
flable
l).
Only
6
of thc
35 survcrrcd rncdicinesrvcre
frxrnd
in at leart four of the
survcycd oudcts. For individual medkints, a completc abcence of more than 459oof the targetcd mcdicinesrvas obscn'ed (16 out of 35) which are
ussd t<, ar€.a irnpofianr disr:ases srch as h.tpertencion, epilcpsy
(plrcnltoiu), d'rat'ctes(metformin),thyroiddirordcn (levorhvroxini)
and asrhna
(salbutamol
and
beclometasone inhalers).Only tw<l nredicincr werc in ctock io at leant 309" of rhc public
helth frllititx
surteyr:d:captopril
(30'q?, aveilability) andchloroquine phosphatc (70,q6 3veihhiliq)- Cltarh, mosr Paiicnts
h:ve to purdrase medicineo hom private rcail pharnracic.
'lt';i:i* t. ";r.r:ll','.::i '.:,1':,,:.,':-, liir.:', r:i.1 :.:;':','ii,,' ::i-'..
?gi-it,r,:.:i .:: ::: :.:1, ..,:'1. :..::, :ii.:11:i,': r J li.
tr::;r ,.' :,il rr- ::,1
8112
iit:I'ivrii?r.,t i:;,3ir:!fi
f prieas
Thc median retail price of originator brands in the privctc sector
in Yemc,n u.as about
l8
times higher than intematianal refcrcnceprice
(Thbled).
Theprico of
there odginator brands varicd bcru'.r:n 2 and 130 rime* morc, with 75% of rhe.m costingg atk:st
7 tinrc.r morr than the interrrarional rfercncc
pricc.
For lorcstpricc generic <quivalents, MPRs varicd from 0.3
to l8
tinresgrcater dran internarional rcfcrcnce prices. The medbn
IIPR
rrar-1. >.
At the individual medicines
lqd.
thc results shos'tfnt:
.
IIPRs of some low<st priccd gencrics werrmrrh
less rhanthc refcrcnce prices, srch as risperidom (0.2O. This ma,v be attr ibutcd to rgistercd chcaper sources Fmm south
md
south-crst,&ia, such as lrrdia, Pakistan.
.
The difen:nces betrvtrn priccs oforiginator brands and thcirlo*'est priced gcneric cquivalcnts wene often vcry high. For
insrance, originator brand ciproflox.xin was 24
tims
highcr prked than thc lowcsr priced gcncric txluir2Ln.. Origirrattirhrands of fluconaz-ole, omcprazrle aod ralritirCinc wcrc a
lirtle over I
I
tinres morc than their lowcst priced gcnericequivalents.
[n somc casts, br>th tlre originatrrr brand and dre lorxtrt priced gcncric cqtrivalent wcre cxcc'ssivcly
cpcnsire
Figrrc 2 illurtrat<x*arnples of high priced nrcdicines (both originator brands and lon'est priced generks) with MPRs rn-er 5.
Acmss
rhc
privatc pharmacics, thcrcwrre
considerable prkerariations for sr>mc
lowsr
priced generk medkines and originrtor brandprodtts,
As shownin
Figure3,
dr
irrerquartih.-g.
for
originator brand glibenclamide nasz0.n
Q5&
F
€.mile)-
56.24 C/5th percentilc),wi&
tlrc m.dirn
MPR
of
5t.92.
For originator brand
diloferrrc
drcrc wzs lers veriability; thc intcr,qurtile rangsrrs
43.4-
52.09 (median lvtPR 44.62).;1,
S
;m;:t*"."
l&fltu&
Crdlo(sn
Brconaztt Glbrn[hfiiJe t/bbehdszde c0
liii*r;: *.
!j::i.::''rr.;,;i0r
:
50 1
T
i
R',D
g.-i
a {1
ii
Et-tr
M
x'+bfFEbFltFi.trd Dicbtctcililirtrbild
Glimc$ti$dv
gffit
hildfi,gi:l::
3.- :l:..; r, , :-..'r 'r 'i,'r, r. ' : ^ i.Slei;ri
Bytli?iiir{?}s
i* ti:s
pr-iv;it* riectrJr
For the 24 nredicines available in private pharmacies as both the,
originator brand and lmvcst priccd gencric equivalenr, th€ leriation
in
price {mcdian brand premium) was 26Vo, i.c. on everagc the cost of the lowest priced gcnerk equivalent vvas a quarrcr of thatof tlre origioator brand produrt- Ttre interguanile range was l59o
-38%-Akhough rhe
rarious sourcesof
medhines {domcstic, Arab countriei, soudr-cast ,fuian countries and Eurog:an producers) may txplain thc largc price rnariations of lx,txt
priccd or bnndedgenerics,
it
is
verydificult
to
givg3
feasible explanation or inrerpretation for originator brand prodrrrs unltxr somcof
thesignificantly'lower ccxt originator brand prodrrts wete imported
from a suhtsidi"rd fact<rr.v in countrics with vcry ehcap labour. f3
ri.;aett:
*t;,tii.i
:. d$!, A ii?sflilr
ti:
ilrr
S a:: r:ii:r,i:!i- i-:?a-lNo
products, cither originatorbran& or
gcnerics, were frxrndin
thc
privare retail pharmacies survr:vodfor
thn:e medioncs: rrcr'irapine, lcrr,astatin and hydrochlorothiaz)de.i ;: *1+; 1'5q'41q,;
tii *rl$lil.*f
is€'irt
The overall price pcoplc pay
for
kru,cs priccd pgnc'ricsin
theprivarc sector was twic€ the patient price
in
drc Aublic sectocend tcn timcs rhe gol€rnmeoa procrrcrnent pt'rc. Howerer, Iow pubiic sector availabiliw makcs
it
difficultto
nrake soundcross-,scctor conclusions except the possibility that ccftriaone inicctior
had lxen purchased from thc locd prirate nrar{<e nrhich would
eccount for the similarity in price across the scctors (privatdpublic
ratio L
l8).
This contrasts wirh a t6-fold &f,er.nce in ttre priccof
gcrreric raniridinc.
i::' j'{i:'.:: i:;i: t:ririr_-}It*,
tt.*
The .rfficial curnulative mark-up in tlrc privais
*.,.r
supply drainis 5?.449(,, whethcr thc nredkinc is imgoned or locallv pnduced.
gcncric or originator
btand.
This includcs a rvhole'sale matk-upof l0qi'
and a pharmacv mark-up of Ltt%. This rcpreseots 379i' of the total paticnt price in the casc of E:neric aciclovir, with thcmanufacturcrls price contributing 63% of rhe
find
pdient prk€(Figurc 4),
,).lj:
I.1ii:,'"t"r"nent data
we
obniml t-mr olicial nums end mr r"elk{aredTir see
if
the official c.umulative mark-upof
5?.44% is appl-kd,paticnt
pric6 of
originatot brandsin
theprivatr
soctor werecompared
to
rcgisercdCIF
pricas.lf
an ofFerof
t1096of
theofficial cumulative marL-up is
applid,
onlyfl
of
26 originatorbrand products bclong to this category Table 5 shou's s.rmc oFthe wide variations in mark-ups, basad
"n
ch< di{fcrcncc .rf rcgiscrcdCIF price and observcd petirnt price.
There r:right
be
sr+'eral nasonsfor
such*'ide
variabilitv incumulative mark-up*:
.
.rf6ciallvset retail nrarginsare violatrrd by rvhoksalcrsandl,rr rsailcrs to incrca.sc profits;
.
registcrcd CIF pricrx are incornrt or manipular.-l te d*reasc liabilirks (thc t % impons;jonfe
for thc cosr r,feach pro-forna invoicc and the 596 custonrs fte for the cost of each shipmcnt);
.
dre oficial margin af 57.441m is not feasiblc and considercdto bc unfair bv mcdicines treders.
Fletd oan{-up 1b-*
ttft&iale d.lr.,Jo 8t
orts c14rs 1%
Tgg4Y
gqzgE di
tEnsfo.rdril 3\
Cudmr d'Jq 3*
tt4r8 $EDo.t ftd 13 frer8hr Co6l" in$rarce.{cFi 6J9c
F:iL.-iis.
4.
a'ri! riCarbamare€tne
-LB,Va
Srritzerlandilq
i.:,+ioiirliitil#+*qg
lil;,+rtr
i.:i:r.
Glib€ndamde
393.8%
E$rpti:i
i:i
liiiiri;ttiii*.
s
:it:
ri
'''':,.:I.r:!-1{}11*1u.*i*B*
r
Because of the limited puhlic procurement data and verylow evailabilitv of rnost nredicinc in public
hr:lth
faciliriesir is
di6nrlt
ro make a rcund;udgemenr abour prrbliclxdth
s<cor prices, rhat is not alsn misleding. Holvevelpubhc procurerncnt appeerd to be efficient for the fcw
srn'Ev'cd medkins bc-rng procured, and pricts paid bv
patients in thc putJic sctor wctt cl()se to procurelneilt
prkcs.
.
Overall the availahiliq'of gcncrics in private t<tailpharmrc'es rvas trcellcot. Otiginator brand producrs rverc
also wir{dy available for m,:st of rhe s.rrvcvcd medicines.
Howewr, the 10096 availabiliw of some third geoerarion
anribiotics, such as ceftriaxonc injcction *'hich is nraint,v
u.eed to trtat meningitis, pneumonia and septicaentia, nra'r'
indicatc the abr:-ri: of tbe nen'er gsncrations of antihiotics.
.
ln conrpa,rison with intcrnational reierence ptices, thc pliccsof lowest pricerl branded-grlerk I gencric rncdrcinr:s in r:bc
prirrate scctor varied from verv chcag to considerablv high
priced- Mosr originator brands werc considcrablv higher
pricrd rhan rhe refcrence
prics
(?5'/ohsd an MPR>7).i.lj :,.1,:,:::- i,:ri: : ii:1' 8n* !hl3E 1%
10t12
.
Almosthglfofthc
priccs of 1 5 originator brands lcrtehigher in l'cmen compared to three Arab crxrntries with
mtrh
highcr GDP per capita, namcly. Jordan, kbanon andKuwait.
.
In comparison with thc registered CIF pricec of medicins'thc cumulative marlaups varied wrddy- Some vrcrcles than
thc officially allowod ma*-up {t7.44Vo) or tr-cn n€atiye
(providing ev-idencc of exagg<ration in rhe registcred CIF
priccs) whilc rxhcrs reflrrt significantly grcatcr mark-up
value*, showiog violation of Yemeni pricing poliry.
tt" i,r* #f 'r't It3#
a'} r3:* f
it
ris
Bascd on the findings of thc strdy, nrommcndations made by
rhe
invtstigatorsto
thc
Govrernmentof
Yenren irK{udrd t}E following.l.
Enhance *re role ofthe public sector to ensurc the anilabiliqv ofall mcdicines on the national ctsentinl list, after rerrising and uprlating the lint to arcommodate ncnt thcrapeutic catcgorits and emerging illncsses.2. Find alternative sources offinancing for thc purchasing oF
medicines and implementing suiublc mechanisms to retionalize
expenditure thc National Health Accounts nrethodolog.v might
be rlscful in this reg;and.
3. Adopt a pricing system that takes into considcration:
.
rvhether medicines are locally produced or imponed; odginator brands or genericsi branded-gcnerics; life saringor otherwise;
o
comparing priceri across a well-chosen range of countri.xwhich use cost-efiectiveness anatyris, taking into account diffcrcnces in thcir wealdr to that ofYemcnl
t
applying regressivc mark-ups that is, sening lorrrrermark-ups for more expensive rn6ll.1not
.
tlre price of theraperrticdly equivrlent products with thcsame risk-bencfi t tradc-offs;
.
using thc registration of ncw medicincx t.r reducethe prices of older brands prodrred by the.same
pharmaccuticd company;
.
compariot pricrx cornpilod by non-pro6t orgahizdion$/institutions strch as Manag9ment Scicncer for Hcalth,
Australian Pharmaccutkds Beneft Scheme and othcr
sourc€s;
.
ccensive usc of pharmaco-economic tools andfir€asurcm€ots, including coat-benefit analvsis'
cost-cffectiveness and,vsic, cost-minimization anabsis and
crxt-{rtil iqv tnd}'s is.
r
srrioeconomic sittntion an lysis of the countEv as wdl astbe affordabiligv of treatments for poor Patients.
4.
Ch6k
and revise rcgistcrcd CIF prico on a fair, rcliable and regular besis, given that prkcs of raw materids are dccrcrsinganoudly fur origlnator braods with the iutroducti.rn ,rf
numeror$ gencric/ btandcd-gencric
quivdcnts-5. Encourage drc prescribing of mcdicincs bv the gencric rame; information diss€minated in thc media and through htalth
ryndicater/ prolessionel associations could play an importanr role
Furf
ir*r
irrfr:rs:rai
ian
Dr Yasccn Ahmod Al-Qgbati
Dircctor of Planning and Statistical Depanment
Suprane Board of Dnrgs and \'ledicat Appliancrx Ministr.v of Health
Email: sbdma@Jrnet.ye
Essential Mcdicincs and Pharmrceuticd Policies Unit
\forld
Hcalth Organization, Regional Ofice fortlr
Eastern MediterraneanAMul
RazzakAl Sanhouri Strc*, PO.Box 7608 Nasr Cky, Cairo, Eg1ryt F- mail : emp@mro.who. intThc fi.rll survry rcport end data can be found at httpJ/www.haiweb,org/modicincprices/survess
@\0orld Health Organization 2008 Document no- VHO-EM/EDB/090/E
12112