Pr oceedings of The 5t hAnnual I nt er nat ional Confer ence Syiah Kuala Univer sit y ( AI C Unsyiah) 2015
I n conj unct ion wit h The 8t hI nt er nat ional Confer ence of Chem ical En gineer ing on Science and Applicat ions ( ChESA) 2015
Sept em ber 9 - 11, 2015, Banda Aceh, I ndonesia
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Sim u la t ion of Con t in u ou s Bio- Re a ct or
Rudy Agust r iyant o
Depart m ent of Ch em ical Engineering, Facult y of Engineering, Universit y of Sur abaya, Surabaya, I ndonesia;
* Cor r esponding Aut hor : rudy.agust riyant o@st aff.ubaya.ac.id
Abst r a ct
Dynam ic st udy of bioprocess syst em plays a cent ral role in bioprocess cont r ol. I t is in fact on t he basis of t he t im e r equired for t he dev elopm ent of t he know ledge process t hat t he t ot al design, analysis and im plem ent at ion of m onit oring and cont r ol m et h ods ar e carried out . Wit hin t he fram ew ork of bioprocesses, t h e m ost nat ural w ay t o det erm ine t h e m odels t hat w ill enable t he charact erizat ion of t he pr ocess dynam ics is t o consider t h e m at erial balance of m aj or com ponent s of t he pr ocess. This art icle will presen t sim ulat ion result s of cont inuous bio- react or . The m at h em at ical m odels for t he bio- react or based on t he m at erial balance had been derived ( Riggs and Karim , 2006) and w ould be adopt ed in t his st u dy. Those m odel w er e solved and sim ulat ed using Mat lab. I t is found t hat t he dynam ic responses of t h e bio- react or du e t o a st ep change in feedrat e ar e first order.
Ke y w or ds: Sim ulat ion, bio- react or, biochem ical, ferm ent at ion
I n t r odu ct ion
Microbial ferm ent at ion is a pr ocess in w hich a populat ion of m icro - organism s ar e grow n using cert ain nut rient s under fav orable sur rou nding condit ions ( t em perat ur e, pH, agit at ion, aerat ion, et c) . I t sch em at ically cor responds t o t he t ransform at ion of subst ances ( generally carbonaceous subst rat es) int o product s, r esult ing from m et abolic act ivit ies of cells.
The m ain com ponent s of t he react ion are as follow s ( Dochain, 2008) :
• Subst rat es, denot ed as Si, w hich ar e necessar y for t he gr ow t h of m icro- organism s, or
ev en w hich are precursor s of a com pound t o be pr oduced. These subst rat es generally cont ain a source of carbon ( glucose, et hanol, et c) and som et im es nit rogen ( NO3, NH4,
et c.) and ph osphorus ( PO4, et c) .
• Microbial biom asses, denot ed as xi.
• End pr oduct s, denot ed as Pi, for agri- foods ( oils, cheese, beer , w ines, et c) , chem ist ry
( solvent s, enzym es, am ino acids, et c) , t he pharm aceut ical indust ry ( ant ibiot ics, horm ones, vit am ins, et c) or for t h e pr oduct ion of en ergy ( bio- et hanol, biogas, et c.) .
Bio- et hanol, as a clean and renew able fuel, is gaining increasing at t ent ion, m ost ly t hrough it s m aj or environm ent al benefit s. I t can be produced from differ en t kinds of r enew able feedst ock such as e.g. sugar can e, corn, w heat , cassava ( first generat ion) , cellulose biom ass ( second gen er at ion) and algal biom ass ( t hird generat ion) . Sanchez and Cardona ( 2008) described t he biot echnological product ion of bio- et hanol fr om different feedst ocks. The agro- indust rial w ast es had been explored for t heir feasibilit y as cult ure m edia for t he product ion of bioet hanol ( Bocan egra et al, 2015 ; Balat , 2011 ) .
