52 Penerbit Salemba Medika; 2008; 2-4 p.
2. Departemen Kesehatan Republik Indonesia (DEPKES RI). Pedoman manajerial pencegahan dan pengendalian infeksi di Rumah sakit dan pelayanan kesehatan lainnya(katalog).DEPKES RI 2007.
3. Peraturan menteri kesehatan republik Indonesia nomor 1691/MENKES/PER/VIII/2011 tentang keselamatan pasien rumah sakit.
4. Group TCCCT.A Randomized Trial of Diagnostic Techniques for Ventilator-associated Pneumonia. The new England Journal of Medicine. 2006 Dec, 21 2006;355(2006):11.
5. Klevens RM, Edwards JR, Richards C, Jr, et al. Estimating health care-associated infections and deaths in U.S. Hospitals, 2002. Public Health Reports. 2007;122:160–6.
6. Shorr AF, Kollef MH. Ventilator-Associated Pneumonia Insight From Recent Clinical Trials. CHEST Journal. 2005;128(5 Suppl 2):583S-91S.
7. Institute for Healthcare Improvement. Ventilator Bundle(Internet).c2010 (update 2013 Maret 15; cited 2013 November 11) Available from: http://www.ihi.org/Engage/Memberships/MentorHospitalRegistry/Pages/Vent ilatorBundle.aspx
8. Institute for Healthcare Improvement. Implement the IHI Ventilator Bundle(internet).c2011(updated 2011 Februari 8; cited 2013 November 11). Available
from:http://www.ihi.org/IHIofferings/MembershipsandNetworks/MentorHosp italRegistry/VentilatorBundle.aspx.
9. World Health Organization.Prevention of Hospital-Acquired Infections: A practical guide 2nd edition(Internet).2002(cited 2013 Desember 27).Available from:
http://www.who.int/csr/resources/publications/drugresist/WHO_CDS_CSR_E PH_2002_12/en/
10. Stubblefield, Heaven.Hospital-Acquired (Nosocomial) Infections(Internet).c2014(Reviewed 2014 Januari 2014; cited 2014 Januari 27). Available from: http://www.healthline.com/health/hospital-acquired-nosocomial-infections.
11. Klevens RM, Edwards JR, Richards CL, Horan TC, Gaynes RP, Pollock DA, et al. Estimating health care-associated infections and deaths in US hospitals, 2002. Public health reports. 2007;122(2):160.
12. Depuydt P, Myny D, Blot S. Nosocomial Pneumonia: aetiology, diagnosis and treatment. Current opinion in pulmonary medicine. 2006;12(3):192-197 13. Behrendt CE. Acute respiratory failure in the United States: incidence and
14. Jones J, Rowan K. Is there a relationship between the volume of work carried out in intensive care and its outcome?.Int J Technol Assess Health Care 1995;11:762-9.
15. American Thoracic Society. Withholding and withdrawing life-sustaining therapy. Ann Intern Med 1991;115:478-85.
16. Amitai, Allon. Ventilator Management (Internet).2013[update 2013 jun 7;cited 2013 Nov 23].Available from: http://www.medscape. com/article/810126.
17. Hunter JD. Ventilator Associated pneumoni.Postgraduate Medical Journal.2006;82(965);172-8.
18. Ibrahim EH, Tracy L, Hill C, Fraser VJ, Kollef MH. The occuranceof ventilator associated pneumonia in a community hospital. Chest 2001;120:555-61.
19. Garrouste OM, Chevret S, Arlet G, et al. Oropharyngeal or gastric colonization and nosocomial pneumonia in adult intensive care unit patients. A prospective study based on genomic DNA analysis. Am J Respir Crit Care Med 1997;156:1647–55.
20. O'Neal PV, Grap MJ, Munro C, Minick P, Sessler C. Factors associated with subglottic secretion accumulation and removal among mechanically ventilated adults. Am J Crit Care 2002;11:290.
21. Cook DJ, Reeve BK, Guyatt GH, et al. Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analyses. JAMA 1996;275:308–14.
22. Berton DC, Kalil AC, Cavalcanti M,Teixeira PJ. Quantitative versus qualitative cultures of respiratory secretions for clinical outcomes in patients with ventilatorassociated pneumonia. Cochrane Database Syst Rev 2008;4:CD006482.
23. Anton Y. Peleg, M.B., B.S., M.P.H., and David C. Hooper, M.D.Hospital-Acquired Infections Dueto Gram-Negative Bacteria. N Engl J Med 2010;362:1804-13.
24. The Canadian Critical Care Trials Group. A randomized trial of diagnostic techniques for ventilator-associated pneumonia.N Engl J Med 2006;355:2619-30.
25. Guidelines for the management of adults with hospital-acquired, ventilatorassociated, and healthcare-associate pneumonia. Am J Respir Crit Care Med 2005;171:388-416.
26. Institute for Healthcare Improvement Web site. Implement the IHI ventilator bundle. http://www.ihi.org/ Home/Knowledge Center/Changes/Implement the IHI Ventilator Bundle.aspx.Accessed November 11, 2013.
27. Institute for Healthcare Improvement. Getting started kit: prevent ventilator-associated pneumonia. How-toguide. 2008.Available at : http://www.premierinc.com/safety/topics/bundling/downloads/03-vap-how-to-guide.pdf. Accessed November,23 2013
28. Guidelines for the management of adults with hospitalacquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med. 2005;171(4):388–416.
29. Institute for Healthcare Improvement. Ventilator bundle compliance. 2011(updated 2011 April 26; cited 2013 November 25). Available from: http://www.ihi.org/knowledge/Pages/Changes/ImplementtheVentilatorBundle .aspx..
30. Institute for Healthcare Improvement. How-to Guide: Prevent Ventilator-Associated Pneumonia. Cambridge: Institute for Healthcare Improvement.2012
31. O’Keefe GE, Caldwell E, Cuschieri J, Wurfel MM, Evans HL. Ventilator associated pneumonia: bacteremia and death after traumatic injury. JTrauma Acute Care Surg. 2012;72(3):713-719.
32. Venkatram S, Nayak J, Kanna B.Safety of daily sedation interruptions in mechanically ventilated inner city patients – an alternative approach. Journal of Medicine and Medical Sciences. 2010;Vol. 1(6). 242-247.
33. Metheny NA, Clouse RE, Chang YH, Stewart BJ, Oliver DA, Kollef MH.Tracheobronchial aspiration of gastric contents in critically ill tube-fed patients: frequency, outcomes, and risk factors. Crit Care Med. 2006;34(4):1-9.
34. Metheny NA, Frantz RA. Head-of-Bed Elevation in Critically Ill Patients: A Review. Critical Care Nurse. 2013;33(3):53-67.
35. John F. McConville, M.D., and John P. Kress, M.D. Weaning Patients from the Ventilator. N Engl J Med 2012;367:2233-9.
36. Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Critical care Medicine. 2002; 30(1).
37. Soliman H, Melot C, Vincent J. Sedative and analgesic practice in the intensive care unit: the result of European survey. British Journal of Anaesthesia. 2001; 87(2).
38. Acang,Nuzirwan. Deep Vein Trombosis.Majalah Kedokteran Andalas.2001; 2(25):46 – 55.
39. Michael J. Armahizer, PharmD; Neal J. Benedict, PharmD. FAST HUG : ICU Prophylaxis. American Society of Health-System Pharmacists 301-657-3000. 40. Samama MM. A comparison of enoxaparin with placebo for the prevention of
venous thromboembolism in acutely ill medical patients. Prophylaxis medical patients with enoxaparin study group. N.Eng.J.Med. 1999; 341:793-800. 41. Wicaksono, Satrio A., Listianto, Jati.,Leksana, Ery. Pengaruh Profilaksis
Trombosis Vena Dalam dengan Heparin subkutan dan Intravena terhadap Aptt dan Jumlah Trombosit pada Pasien Kritis di ICU RSUP Dr.Kariadi Semarang. Jurnal Anestiologi Indonesia. 2012;IV(3) : 171.
42. Pogorzelska,M., Stone,W., et al 2011 Impact of the ventilator bundle on ventilator associated pneumonia in intensive care unit, International Journal for quality in Health Care, 23, 538-544.
43. Ozurt, Sungkurtekin, Adyemir, Atalay, et al 2007. Ventilator Associated Pneumonia. Retrospective Result in Intensive Care unit.The Internet Journal of gastroenterology,5.
44. Clark, Lam LT, Gibson S, Currow D (2009). The effect of Ranitidine versus Proton Pump Inhibitors on Gastric Secretions : a meta-analysis of randomized control trials.Anasthesia. Jun;64(6) Pp: 652-7.
45. Weinstein, R A, Bonten, M J, Kollef, M H, & HALL, J B.2004. Risk factors for ventilator-associated pneumonia from epidiemology to patient management clinicical infectious disease, 38, 1141-1149.
Lampiran 1.
LEMBAR PENELITIAN
Ruang perawatan Intensive Care Unit (ICU)
No Kriteria Data 1. No. CM RSDK 2. No. CM penelitian 3. Nama L/P 5. Tanggal Lahir 6. Alamat 7. Indikasi penggunaan ventilator mekanik Gagal Napas Penurunan kesadaran
Frekuensi napas > 35x/menit Hipoksemia
Komplikasi kardiovaskuler Komplikasi lain
Telah menggunakan NIPPV lainnya
8. Tanggal masuk ICU / / Jam 9. Mulai penggunaan Ventilator
mekanik / / Jam Berakhir penggunaan Ventilator mekanik / / jam 10. Ventilator bundle
(Head Of the Bed) 30 º sampai 45 º, kecuali kontraindikasi medis
frakturspinal, frakturpelvis,
Intra-Aortic Balloon Pump (IABP ulkus parah akibat tekanan pada daerah
sacrum Penghentian secara berkala
agen sedasi dan penilaian kesiapan ekstubasi
Obat sedasi : midazolam lorazepam
dexmedetomidine atau propofol Lainnya
profilaksis trombosis vena dalam (kecuali kontraindikasi medis) Obat Profilaksis TVD Heparin Enoxaparin (Lovenox) Nandroparin Fraxiparin Lainnya Profilaksis ulkus peptikum
Obat yang digunakan : PPI
Sukralfat Antagonis H2 Lainnya Oral care secara berkala
dengan chlorhexidine
0,12% 0,2%
Lainnya
Kontraindikasi lainnya Pasien on pressors (vasopressor) Pasien dengan ciri-ciri kematian Pasien dengan blokade neuromuscular Pasien dengan resiko perdarahan
Lampiran 4 DOKUMENTASI Lampiran 3 Biodata Mahasiswa
Identitas
Nama : Dea Aulia Futaci
NIM : 22010110120106
Tempat tanggal lahir : Majalengka,16 Maret 1992 Jenis Kelamin : Perempuan
Alamat : Ds.sindang no.61 Rt/Rw 01/004 Blok.Salasa kec.Cikijing Kab.Majalengka.Jawa barat
No. HP : 083838071100
Email : [email protected]
Riwayat Pendidikan Formal :
1. SD : SDN SINDANG 1 Lulus tahun: 2004
2. SMP : SMP N 1 KUNINGAN Lulus tahun: 2007
3. SMA : SMA N 2 KUNINGAN Lulus tahun: 2010
