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DAFTAR PUSTAKA

1. World Health Organization. Global status report on noncommunicable diseases 2014. Geneva: World Health Organization; 2014.

2. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2224–60.

3. World Health Statistics. Causes of death 2008 : data sources and methods. World Health. 2011;2010(September 2010):1–28.

4. Cardiovascular disease risk factors - Hypertension [Internet]. World Heart Federation. [cited 2016 Jan 17]. Available from: http://www.world-heart-

federation.org/cardiovascular-health/cardiovascular-disease-risk-factors/hypertension/

5. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352(16):1685–95.

6. D’Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008 Feb 12;117(6):743–53.

7. Bouhanick B, Barbosa SLS, Marre M. Hypertension and diabetes. Arch Mal Coeur Vaiss. 2000;93(11, S):1429–34.

8. IDF Diabetes ATLAS. 7th ed. Brussels: International Diabetes Federation; 2015. 12-7 p.

9. WHO | Diabetes [Internet]. World Health Organization; [cited 2015 Nov 23]. Available from: http://www.who.int/mediacentre/factsheets/fs312/en/

10. American Heart Association. Cardiovascular Disease & Diabetes [Internet].

[cited 2015 Nov 23]. Available from:

http://www.heart.org/HEARTORG/Conditions/Diabetes/WhyDiabetesMatters/ Cardiovascular-Disease-Diabetes_UCM_313865_Article.jsp/#.VlJnCtLhDIV

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European Guidelines on Cardiovascular Disease Prevention in Clinical Practice. The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J. 2012;33(13):1635–701.

12. Hong YM. Atherosclerotic cardiovascular disease beginning in childhood. Korean Circ J. 2010;40(1):1–9.

13. O’Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson Jr. SK. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999;340(1):14–22.

14. Gómez-Marcos MA, Recio-Rodríguez JI, Rodríguez-Sánchez E, Patino-Alonso MC, Magallón-Botaya R, Martínez-Vizcaino V, et al. Carotid Intima-Media Thickness in Diabetics and Hypertensive Patients. Rev Española Cardiol (English Ed. Elsevier; 2011 Jul 1;64(7):622–5.

15. Alatab S, Fakhrzadeh H, Sharifi F, Mostashfi A, Mirarefin M, Badamchizadeh Z, et al. Impact of hypertension on various markers of subclinical atherosclerosis in early type 2 diabetes. J Diabetes Metab Disord. 2014;13(1):24.

16. Marieb EN, Hoehn K. Human Anatomy & Physiology. 7th ed. San Francisco: Benjamin Cummings; 2006.

17. Mescher AL. Junqueiras’s Basic Histology: Text and Atlas. 13th ed. New York: McGraw-Hill Education; 2013. 217-24 p.

18. Kumar V, Abbas AK, Aster JC. Robbins Basic Pathology. 9th ed. Philadelphia: Elsevier Saunders; 2013. 335-43 p.

19. Libby P. The Pathogenesis, Prevention, and Treatment of Atherosclerosis. In: Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine. 19th ed. McGraw-Hill Education; 2015. p. 291e1–10.

(3)

2015 Jan 29;16(5):9749–69.

21. Sherwood L. Fisiologi Manusia: dari Sel ke Sistem. 6th ed. Jakarta: Penerbit Buku Kedokteran EGC; 2012.

22. Finn A V, Nakano M, Narula J, Kolodgie FD, Virmani R. Concept of vulnerable/unstable plaque. Arterioscler Thromb Vasc Biol. 2010 Jul 1;30(7):1282–92.

23. Antman EM, Loscalzo J. Ischemic Heart Disease. In: Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine. 19th ed. McGraw-Hill Education; 2015. p. 1578–92.

24. Coronary Artery Disease [Internet]. National Library of Medicine; [cited 2016

Jan 9]. Available from:

https://www.nlm.nih.gov/medlineplus/coronaryarterydisease.html

25. Coronary Artery Disease - Coronary Heart Disease [Internet]. [cited 2016 Jan

9]. Available from: Ilmu Penyakit Dalam. 6th ed. Jakarta: InternaPublishing; 2014. p. 1518–28. 27. Ropper AH, Samuels MA. Cerebrovascular Disease. In: Adams and Victor’s

Principle of Neurology. 9th ed. New York: McGraw-Hill; 2009. p. 746.

28. Ischemic Stroke | Internet Stroke Center [Internet]. [cited 2016 Jan 17]. Available from: http://www.strokecenter.org/patients/about-stroke/ischemic-stroke/

29. History of the Framingham Heart Study [Internet]. [cited 2016 Jan 8]. Available from: https://www.framinghamheartstudy.org/about-fhs/history.php 30. Hackam DG, Anand SS. Emerging Risk Factors for Atherosclerotic Vascular

Disease: A Critical Review of the Evidenc. JAMA. 2003;290(7):932–40. 31. Strom JB, Libby P. Atherosclerosis. In: Lily L, editor. Pathophysiology of

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Sudoyo AW, Setiyohadi B, Sumandibrata K M, Syam AF, editors. Buku Ajar Ilmu Penyakit Dalam. 6th ed. Jakarta: InternaPublishing; 2014. p. 1427–37. 33. Grundy SM, Cleeman JI, Merz CNB, Brewer HB, Luther T, Hunninghake

DB, et al. Implications of Recent Clinical Trials for the Natinal Cholesterol Education Program Adult Treatment Panel III Guidelines. Arterioscler Thromb Vasc Biol. 2004;24:e149–61.

34. European Society of Hypertension - European Society of Cardiology Guidelines Committee. European Society of Hypertension - European Society of Cardiology Guidelines for The Management of Arterial Hypertension. J Hypertens. 2003;21(1011):53.

35. Chobanian A V., Bakris GL, Black HR, Cushman WC, Green L a., Izzo JL, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206–52.

36. Kementrian Kesehatan RI. Infodatin Hipertensi. Jakarta; 2014.

37. Tedjasukmana P. Tata Laksana Hipertensi. Cdk-192. 2012;39(4):251–5. 38. Alexander RW. Hypertension and the Pathogenesis of Atherosclerosis :

Oxidative Stress and the Mediation of Arterial Inflammatory Response: A New Perspective. Hypertension. Lippincott Williams & Wilkins; 1995 Feb 1;25(2):155–61.

39. Purnamasari D. Diagnosis dan klasifikasi diabetes mellitus. In: Setiati S, Alwi I, Sudoyo AW, Simadibrata M, Setiyohadi B, Syam AF, editors. Buku Ajar Ilmu Penyakit Dalam. 6th ed. Jakarta: InternaPublishing; 2014. p. 2325–9. 40. Powers AC. Diabetes Mellitus: Complications. In: Kasper DL, Hauser SL,

Jameson JL, Fauci AS, Longo DL, Loscalzo J, editors. Harrison’s Principles of Internal Medicine. 19th ed. McGraw-Hill Education; 2015. p. 2422–30.

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42. Rask-madsen C, King GL. Review Vascular Complications of Diabetes : Mechanisms of Injury and Protective Factors. Cell Metab. Elsevier Inc.; 2012;17(1):20–33.

43. Chehade JM, Gladysz M, Mooradian AD. Dyslipidemia in Type 2 Diabetes : Prevalence , Pathophysiology , and Management. Drugs. 2013;73:327–39. 44. Fodor G. Clinical Evidence Handbook: Primary Prevention of CVD: Treating

Dyslipidemia. Am Fam Physician. 2011;83(10):1207–8.

45. Adam JMF. Dislipidemia. In: Setiati S, Alwi I, Sudoyo AW, Simadibrata K. M, Setiyohadi B, Syam AF, editors. Buku Ajar Ilmu Penyakit Dalam. 6th ed. Jakarta: InternaPublishing; 2014. p. 2551–60.

46. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001 May 16;285(19):2486–97.

47. Ballantyne CM, O’Keefe Jr. JH, Gotto Jr. AM. Dyslipidemia & Atherosclerosis Essentials 2009. 4th ed. Jones & Bartlett Publishers; 2009. 48. Centers for Disease Control and Prevention, National Center for Chronic

Disease Prevention and Health Promotion, Office on Smoking and Health. Cardiovascular Diseases. In: How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General. Centers for Disease Control and Prevention (US); 2010. 49. Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an

independent risk factor for cardiovascular disease: a 26- year follow-up of participants in the Framingham Heart Study. Circulation. 1983 May 1;67(5):968–77.

50. Lovren F, Teoh H, Verma S. Obesity and atherosclerosis: mechanistic insights. Can J Cardiol. 2015 Feb;31(2):177–83.

51. Bowles DK, Laughlin MH. Mechanism of beneficial effects of physical activity on atherosclerosis and coronary heart disease. J Appl Physiol. 2011;111(21):308–10.

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53. Vitale C, Miceli M, Rosano GMC. Gender-specific characteristics of atherosclerosis in menopausal women: risk factors, clinical course and strategies for prevention. Climacteric. 2007 Oct;10 Suppl 2:16–20.

54. Nasir K, Michos ED, Rumberger JA, Braunstein JB, Post WS, Budoff MJ, et al. Coronary artery calcification and family history of premature coronary heart disease: sibling history is more strongly associated than parental history. Circulation. 2004 Oct 12;110(15):2150–6.

55. Nasir K, Budoff MJ, Wong ND, Scheuner M, Herrington D, Arnett DK, et al. Family history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2007 Aug 7;116(6):619–26.

56. Michos ED, Vasamreddy CR, Becker DM, Yanek LR, Moy TF, Fishman EK, et al. Women with a low Framingham risk score and a family history of premature coronary heart disease have a high prevalence of subclinical coronary atherosclerosis. Am Hear J. 2005 Dec;150(6):1276–81.

57. Fruchart J-C, Nierman MC, Stroes ESG, Kastelein JJP, Duriez P. New risk factors for atherosclerosis and patient risk assessment. Circulation. 2004 Jun 15;109(23 Suppl 1):III15–9.

58. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986. p. 1399–406.

59. de Groot E, van Leuven SI, Duivenvoorden R, Meuwese MC, Akdim F, Bots ML, et al. Measurement of carotid intima–media thickness to assess progression and regression of atherosclerosis. Nature. 2008;5(5):280–8.

60. Simova I. Intima-media thickness: Appropriate evaluation and proper measurement, described. E-journal Cardiol Pract. 2015;13.

61. O’Leary DH, Bots ML. Imaging of atherosclerosis: carotid intima-media thickness. Eur Heart J. 2010;31(14):1682–9.

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intima-media thickness measurements in carotid and femoral arteries. Invest Radiol. 2000 Dec;35(12):699–706.

63. Touboul P-J, Labreuche J, Vicaut E, Belliard J-P, Cohen S, Kownator S, et al. Country-based reference values and impact of cardiovascular risk factors on carotid intima-media thickness in a French population: the “Paroi Artérielle et Risque Cardio-Vasculaire” (PARC) Study. Cerebrovasc Dis. 2009 Jan;27(4):361–7.

64. Stein JH, Korcarz CE, Hurst RT, Lonn E, Kendall CB, Mohler ER, et al. Use of Carotid Ultrasound to Identify Subclinical Vascular Disease and Evaluate Cardiovascular Disease Risk: A Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force Endorsed by the Society for Vascular Medicine. J Am Soc Echocardiogr. 2008;21(2):93–111.

65. Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, B??hm M, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2013;34(28):2159–219.

66. Folkow B. Cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension. Clin Sci Mol Med Suppl. 1978;4:3s – 22s.

67. Gaballa MA, Jacob CT, Raya TE, Liu J, Simon B, Goldman S. Large Artery Remodeling During Aging : Biaxial Passive and Active Stiffness. Hypertension. 1998 Sep 1;32(3):437–43.

68. Tanaka H, Dinenno FA, Monahan KD, Desouza CA, Seals DR. Carotid artery wall hypertrophy with age is related to local systolic blood pressure in healthy men. Arter Thromb Vasc Biol. 2001;21(1):82–7.

69. Department of Chronic Diseases and Health Promotion. Global Physical Activity Questionnaire. Geneva: World Health Organization; 2012. 1-8 p. 70. Kusumawardani RP. Kontribusi hipertensi terhadap aterosklerosis arteri

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71. Katakami N, Yamasaki Y, Ayaishi-Okano R, Ohtoshi K, Kaneto H, Matsuhisa M, et al. Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. Diabetologia. 2004;47:1906–13.

72. Stettler C, Allemann S, Ju P. Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus : Meta-analysis of randomized trials. Am Hear J. 2006;152(1):27–38.

73. Sutton-tyrrell K, Lassila HC, Meilahn E, Bunker C, Matthews KA, Kuller LH. Carotid Atherosclerosis in Premenopausal and Postmenopausal Women and Its Association With Risk Factors Measured After Menopause. Stroke. 1998;29(6):1116–21.

74. Im TS, Chun EJ, Lee MS, Adla T, Kim JA, Choi S Il. Grade-response relationship between blood pressure and severity of coronary atherosclerosis in asymptomatic adults : assessment with coronary CT angiography. Int J Cardiovasc Imaging. 2014;30:105–12.

75. Darmawan A, Tugasworo D, Pemayun TGD. Hiperglikemia dan Aterosklerosis Arteri Karotis Interna pada Penderita Pasca Stroke Iskemik. M Med Indones. 2011;45(1):1–7.

76. Fromm A, Haaland ØA, Naess H, Thomassen L, Waje-andreassen U. Risk factors and their impact on carotid intima-media thickness in young and middle-aged ischemic stroke patients and controls : The Norwegian Stroke in the Young Study. BMC. 2014;7(176):1–8.

77. Johnson ML, Pietz K, Battleman DS, Beyth RJ. Prevalence of Comorbid Hypertension and Dyslipidemia and Associated Cardiovascular Disease. Am J Manag Care. 2004;10(12):926–32.

78. Mihardja L, Soetrisno U, Soegondo S. Prevalence and clinical profile of diabetes mellitus in productive aged urban Indonesians. J Diabetes Investig. 2014;5(5):507–12.

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Lampiran 1.

PROSEDUR PENGUKURAN CIMT

1) Memposisikan pemeriksa dan pasien senyaman mungkin dimana pasien terbaring pada tempat tidur dan pemeriksa duduk di samping kanan pasien. 2) Mengekstensikan leher dan memposisikan kepala pasien menoleh

kontralateral terhadap sisi leher yang akan diperiksa, kemudian mengoleskan gel pada leher atau pada transduser.

3) Melakukan skrinning arteri karotis komunis menggunakan transduser dengan orientasi transversal, dari proksimal hingga distal, sambil melihat layar monitor hingga menemukan bulbus karotikus.

4) Memposisikan orientasi transduser menjadi longitudinal pada sisi lateral arteri karotis kemudian merekam pencitraan pada monitor dalam bentuk gambar diam.

5) Melakukan pengukuran CIMT pada dinding jauh pembuluh darah menggunakan perangkat lunak pada alat.

6) Melakukan pemeriksaan dan pengukuran CIMT pada sisi leher yang lain dengan cara yang sama.

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Lampiran 5. Kuesioner

DAFTAR TILIK PENELUSURAN REKAM MEDIK DAN

WAWANCARA

No. CM :

Nama :

Jenis kelamin : Laki-laki Perempuan

Umur :

Pekerjaan :

Alamat :

No. HP :

Tinggi badan : _____cm Berat badan : _____ kg BMI : _____ kg/m2 Kontrol teratur/tidak : Ya Tidak

Status merokok : Ya Tidak

Data

Hipertensi

Tekanan darah terakhir

Lama hipertensi Obat yang diminum

Data DM

Status DM : Ya Tidak

Anamnesis 3P + kadar GDS Anamnesis 3P + kadar GDP

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2PP ______mg/dl Kadar HbA1c :

Lama DM :

Obat yang diminum : Data dislipidemia

Status dislipidemia : Ya Tidak

Kadar kolesterol total : ________ mg/dl (dislipidemia: ≥240 mg/dl) Kadar kolesterol LDL : ________ mg/dl (dislipidemia: ≥160 mg/dl) Kadar kolesterol HDL : ________ mg/dl (dislipidemia: <40 mg/dl) Kadar trigliserida : ________ mg/dl (dislipidemia: ≥200 mg/dl) Lama dislipidemia :

Obat yang diminum :

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GLOBAL PHYSICAL ACTIVITY QUESTIONNAIRE (GPAQ)

Jenis Aktivitas Contoh Aktivitas

Aktivitas ringan Duduk, berdiri, mencuci piring, memasak, menyetrika, bermain musik, menonton tv, mengemudikan kendaraan, berjalan perlahan

Aktivitas sedang Menyapu, mengepel, mencuci mobil, menanam tanaman, memanen tanaman, menimba air, bersepeda pergi pulang beraktivitas,

Aktivitas berat Membawa barang berat, berkebun (menggali), bersepeda (16-22km/jam), bermain sepak bola,

Olahraga sedang

Aerobik low-impact, berkuda, voli, berjalan sedang dan cepat, bowling, golf, tenis meja, berenang, bersepeda, jogging, menari, tai chi, yoga, kriket

Olahraga berat Sepak bola, basket, gym angkat berat, berlari, rugby, tennis, aerobik high-impact, aerobik air, menari ballet, berenang cepat

Aktivitas fisik

Kode Pertanyaan Jawaban

Aktivitas saat belajar / bekerja

(Aktivitas termasuk kegiatan belajar, latihan, aktivitas rumah tangga, dll P1

Apakah aktivitas sehari- hari Anda, termasuk

aktivitas berat (seperti membawa beban berat, menggali atau pekerjaan konstruksi lain ) ?

1. Ya

2. Tidak (langsung ke P4)

P2 Berapa hari dalam seminggu Anda

melakukan aktivitas berat? hari P3 Berapa lama dalam sehari biasanya Anda

melakukan aktivitas berat?

Jam menit

P4

Apakah aktivitas sehari-hari Anda termasuk

aktivitas sedang yang menyebabkan peningkatan nafas dan denyut nadi, seperti mengangkat beban ringan dan jalan sedang (minimal 10 menit secara kontinyu) ?

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Perjalanan ke tempat aktivtias, berbelanja, beribadah diluar, dll)

P7 Apakah Anda berjalan kaki atau bersepeda untuk pergi ke suatu tempat minimal 10 menit kontinyu ?

1. Ya

2. Tidak (langsung ke P10)

P8 Berapa hari dalam seminggu Anda

berjalan kaki atau bersepeda untuk pergi ke suatu tempat?

hari

P9 Berapa lama dalam sehari biasanya Anda

berjalan kaki atau bersepeda untuk pergi ke suatu tempat?

Jam menit

Aktivitas rekreasi (Olaraga, fitnes, dan rekreasi lainnya)

P10

Apakah Anda melakukan olahraga, fitnes, atau rekreasi yang berat seperti lari, sepak bola atau rekreasi lainnya yang mengakibatkan peningkatan nafas dan denyut nadi secara besar (minimal dalam 10 menit secara kontinyu)?

1. Ya

2. Tidak (langsung ke P13)

P11

Berapa hari dalam seminggu biasanya anda melakukan olahraga, fitness, atau rekreasi yang tergolong berat?

hari

P12

Berapa lama dalam sehari biasanya anda melakukan olahraga, fitness, atau rekreasi yang tergolong berat?

Jam menit

P13

Apakah Anda melakukan olahraga, fitness, atau rekreasi yang tergolong sedang seperti berjalan cepat, bersepeda, berenang, voli yang mengakibatkan peningkatan nafas dan denyut nadi (minimal dalam 10 menit secara kontinyu)?

1. Ya lainnya yang tergolong sedang?

hari

P15

Berapa lama dalam sehari biasanya anda melakukan olahraga, fitness, atau rekreasi yang tergolong sedang?

Jam menit

Aktivitas menetap (Sedentary behavior)

Aktivitaas yang tidak memerlukan banyak gerak seperti duduk saat bekerja, duduk saat di kendaraan, menonton televisi, atau berbaring, KECUALI tidur

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No

DM DM

(tahun) dislipidemia

aktivitas

fisik (mm) Aterosklerosis

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Lampiran 7. Hasil Analisis Statistik Frequencies

Frequency Table

Je nis kelamin

15 46.9 46.9 46.9

17 53.1 53.1 100.0

32 100.0 100.0

Laki-laki

Perempuan

Total Valid

Frequency Percent Valid Percent

Cumulative Percent

Usia

5 15.6 15.6 15.6

8 25.0 25.0 40.6

19 59.4 59.4 100.0

32 100.0 100.0

Frequency Percent Valid Percent

Cumulative Percent

Obesitas

17 53.1 53.1 53.1

15 46.9 46.9 100.0

32 100.0 100.0

Ya

Tidak Total Valid

Frequency Percent Valid Percent

Cumulative Percent

DM

16 50.0 50.0 50.0

16 50.0 50.0 100.0

32 100.0 100.0

Ya

Tidak Total Valid

Frequency Percent Valid Percent

Cumulative Percent

Dislipide mia

22 68.8 68.8 68.8

10 31.3 31.3 100.0

32 100.0 100.0

Ya Tidak

Total Valid

Frequency Percent Valid Percent

Cumulative Percent

Tingka t aktivitas fisik

21 65.6 65.6 65.6

Frequency Percent Valid Percent

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Jenis kelamin * DM

N of Valid Cases

Value df

Computed only for a 2x2 table a.

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Mann-Whitney Test

Mann-Whitney U 104.500

Wilcoxon W 240.500

Z -1.008

Asymp. Sig. (2-tailed) .313

Exact Sig. [2*(1-tailed Sig.)] .381b

a. Grouping Variable: DM b. Not corrected for ties.

Obesitas * DM

N of Valid Cases

Value df

Asymp. Sig. (2-sided)

4 cells (66.7%) have expected count less than 5. The minimum expected count is 2.50.

a.

N of Valid Cases

Value df

Computed only for a 2x2 table a.

0 cells (.0%) have expected count less than 5. The minimum expected count is 7. 50.

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Tingkat aktivitas fisik * DM

N of Valid Cases

Value df

Computed only for a 2x2 table a.

0 cells (.0%) have expected count less than 5. The minimum expected count is 5. 00. N of Valid Cases

Value df

Asymp. Sig. (2-sided)

4 cells (66.7%) have expected count less than 5. The minimum expected count is 1.50.

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Mann-Whitney Test

Mann-Whitney U 118.000

Wilcoxon W 254.000

Z -.450

Asymp. Sig. (2-tailed) .653

Exact Sig. [2*(1-tailed Sig.)] .724b

a. Grouping Variable: DM b. Not corrected for ties.

Riwayat merokok*DM

Riwayat merokok * DM Crosstabulation DM

Pearson Chi-Square 1.166a

1 .280

Continuity Correctionb .518 1 .472

Likelihood Ratio 1.174 1 .279

Fisher's Exact Test .473 .236

Linear-by-Linear

Association 1.130 1 .288

N of Valid Cases 32

a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 6.50.

b. Computed only for a 2x2 table

Derajat hipertensi*DM

Derajat hipertensi * DM Crosstabulation

DM

Total

Ya Tidak

Derajat hipertensi HT derajat 2 Count 3 5 8

% within Derajat hipertensi 37.5% 62.5% 100.0%

HT derajat 1 Count 6 8 14

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Total Count 16 16 32

% within Derajat hipertensi 50.0% 50.0% 100.0%

Chi-Square Tests

a. 2 cells (33.3%) have expected count less than 5. The minimum expected count is 4.00.

Mann-Whitney Test

Mann-Whitney U 93.000

Wilcoxon W 229.000

Z -1.413

Asymp. Sig. (2-tailed) .158

Exact Sig. [2*(1-tailed Sig.)] .196b

a. Grouping Variable: DM b. Not corrected for ties.

Lama hipertensi*DM

Lama hipertensi * DM Crosstabulation

DM

Linear-by-Linear Association .215 1 .643

N of Valid Cases 32

a. 4 cells (66.7%) have expected count less than 5. The minimum

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Mann-Whitney Test

Mann-Whitney U 118.500

Wilcoxon W 254.500

Z -.426

Asymp. Sig. (2-tailed) .670

Exact Sig. [2*(1-tailed Sig.)] .724b

a. Grouping Variable: DM b. Not corrected for ties.

Explore

Jenis Kelamin-CIMT (DM - Non DM)

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Obesitas-CIMT (DM)

Dislipidemia-CIMT (DM – Non DM)

Case Summaries

CIMT

DM Dislipidemia N Mean Std. Deviation Median Minimum Maximum

Ya Ya 13 1.0185 .44784 .9300 .51 2.22

Tingkat aktivitas fisik-CIMT (DM – Non DM)

Case Summaries

Deviation Median Minimum Maximum

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Explore

Riwayat merokok-CIMT (DM-Non DM)

Case Summaries

16 .9456 .43066 .8550 .51 2.22

16 .7525 .32298 .7100 .35 1.64

32 .8491 .38709 .7500 .35 2.22

DM Ya

Tidak Total

N Mean Std. Deviation Median Minimum Maximum

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Mann-Whitney Test

Jenis kelamin (Keseluruhan) Explore

Tests of Normality

Jenis kelamin

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT Laki-laki .229 15 .033 .850 15 .017

Perempuan .137 17 .200* .908 17 .092

*. This is a lower bound of the true significance. a. Lilliefors Significance Correction

NPar Tests

N Mean Rank Sum of Ranks

Test Statisticsb

Not corrected for ties. a.

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Usia (Keseluruhan) Explore

Tests of Normality

Usia

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT 20-39 .308 5 .136 .834 5 .148

40-49 .325 8 .013 .810 8 .036

50-59 .153 19 .200* .872 19 .016

*. This is a lower bound of the true significance. a. Lilliefors Significance Correction

NPar Tests

Kruskal-Wallis Test

Obesitas (Keseluruhan) Explore

Tests of Normality

Obesitas

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT Ya .166 17 .200* .872 17 .024

Tidak .166 15 .200* .911 15 .141

(32)

NPar Tests

Mann-Whitney Test

Ranks

Obesitas N

Mean Rank

Sum of Ranks

CIMT Ya 17 18.65 317.00

Tidak 15 14.07 211.00

Total 32

Dislipidemi (Keseluruhan) Explore

Tests of Normality

Dislipidemia

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT Ya .149 22 .200* .865 22 .006

Tidak .150 10 .200* .931 10 .454

*. This is a lower bound of the true significance.

(33)

NPar Tests

Mann-Whitney Test

Ranks

Dislipidemia N

Mean Rank

Sum of Ranks

CIMT Ya 22 19.30 424.50

Tidak 10 10.35 103.50

Total 32

Tingkat aktivitas fisik (Keseluruhan) Explore

Tests of Normality

Tingkat aktivitas fisik

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT Rendah .186 21 .055 .826 21 .002

Sedang .165 8 .200* .965 8 .856

Tinggi .290 3 . .926 3 .475

(34)

NPar Tests

Kruskal-Wallis Test

Riwayat merokok (Keseluruhan) Explore

Tests of Normality

Riwayat merokok

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

CIMT Ya .196 13 .182 .879 13 .069

Tidak .165 19 .189 .898 19 .045

(35)

NPar Tests

Mann-Whitney Test

Ranks

Riwayat

merokok N

Mean Rank

Sum of Ranks

CIMT Ya 13 18.00 234.00

Tidak 19 15.47 294.00

(36)

Penjelasan penelitian dan wawancara oleh penulis

(37)

Lampiran 9.

BIODATA MAHASISWA

Identitas

Nama : Mutiara Chairsabella

NIM : 22010112130070

Tempat/Tanggal Lahir: Semarang, 5 September 1994 Jenis Kelamin : Perempuan

Alamat : Jl. Wamena Raya D.194/195 Beji, Ungaran No. Handphone : 081321347312

Email : chairsa@live.com

Riwayat Pendidikan Formal

1. SD : SDIT Assalamah Ungaran Lulus tahun: 2006 2. SMP : SMP Semesta Semarang Lulus tahun: 2009 3. SMA : SMA Semesta Semarang Lulus tahun: 2012 4. S1 : Fakultas Kedokteran Universitas Diponegoro Masuk tahun: 2012

Keanggotaan Organisasi

1. Bidang Hubungan Luar HIMA KU Undip tahun 2013 s/d 2014 2. AMSA Undip tahun 2013 s/d 2014

Publikasi Ilmiah

1. Mutiara Chairsabella, Valensa Yosephi, Yustina Wahyuningtiyas, Kis Djamiatun. Vaksin Vektor Virus Penguat BCG Sebagai Upaya Eliminasi Tuberkulosis (TB). JIMKI, 2016, Volume 4, Nomor 1, Halaman 24-34

Prestasi

Referensi

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