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A 70 -year old man with aphasia and right sided hemiplegia

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(1)

A 10 month old infant with status epilepticus

Teaching NeuroImages

Neurology

Resident and Fellow Section

© 2016 American Academy of Neurology

(2)

Vignette

• A 10 month old infant was brought to the hospital in status epilepticus, preceded by a two day history of fever and loose stools.

Biswas, et al

© 2016 American Academy of Neurology

(3)

Imaging

Biswas, et al

© 2016 American Academy of Neurology

(4)

Acute necrotising encephalopathy of childhood: Neuroimaging findings

• Acute necrotising encephalopathy of childhood (ANEC) is a fulminant encephalopathy affecting infants and children.1

• Viral infections (influenza, rotavirus, HHV-6), immune mediated, and genetic (RANBP2 mutation) etiologies have been implicated as causative factors.2,3

• The trilaminar appearance on DWI and ADC images, and symmetric thalamic involvement is

characteristic.

Biswas, et al

© 2016 American Academy of Neurology

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