Table S1. ABO match distribution in PBSC and BM transplants (p=0.0047 at chi-square test).
BM transplants
N (%)
PBSC transplants
N (%)
Total
N (%) p*
ABO-matched 83 (56.46)
140 (49.12)
223
(51.62) 0.1560 Major ABO-I 39
(26.53)
55 (19.30)
94
(21.76) 0.0866 Minor ABO-I 21
(14.29)
61 (21.40)
82
(18.98) 0.9191 Bidirectional
ABO-I
4 (2.72)
29 (10.18)
33
(7.64) 0.0065
*p-value at Fisher’s exact test.
Table S2. Comparison of cumulative incidence of engraftment in Minor ABO-I and ABO- matched transplants. P-values at Grey’s test are displayed.
PBSC transplants BM transplants
Minor ABO-I vs ABO-matched
p
Bi-directional ABO- I vs ABO-matched
p
Minor ABO-I vs ABO-matched
p
Bidirectional ABO-I vs ABO-matched
p Neutrophil
engraftment 0.1305 0.4127 0.0035 0.6170
Platelet
engraftment 0.2045 0.2953 0.0368 0.8298
Reticulocyte
engraftment 0.1990 0.7794 <0.0001 0.3637
Table S3. Causes of death and survival in patients grouped according to the presence of Major ABO-I.
*p-value at Fisher exact test. a Other causes included solid cancers in 2 patients and murder in 1.
Major ABO-I N=94
Other ABO Matches
N=338 p*
All deaths 42 (44.7) 114 (33.7) 0.0531
Survival (months) 5.2 (2.0-12.6) 5.2 (1.6-14.5) 0.9315 Cause of death
Primary disease 15 (15.9) 52 (15.4) 0.8730
Infection 16 (17.0) 36 (10.6) 0.1067
GVHD 8 (8.5) 17 (5.0) 0.2136
Hemorrhage 0 3 (0.9) 1.0000
Graft failure 1 (1.0) 2 (0.6) 0.5219
Othera 1 (1.0) 2 (0.6) 0.5219
Missing 1 (1.0) 2 (0.6) 0.5219
Survival (months)
Primary disease 11.0 (4.0-17.6) 10.5 (5.0-17.8) 0.6517 Infection 3.5 (0.8-9.0) 1.4 (0.5-6.0) 0.1647 GVHD 4.4 (1.9-20.5) 4.5 (2.7-18.1) 0.4314
Figure S1. Neutrophil, platelet and reticulocyte engraftment in patients receiving bone marrow (BM) or peripheral blood stem cell (PBSC) grafts.
Figure S2. RBC and platelet transfusion discontinuation in patients receiving bone marrow (BM) or peripheral blood stem cell (PBSC) grafts.
