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MAJ14-171 Bowling et al

Supplemental Materials

Table S1. Distribution of estimated glomerular filtration rate (eGFR) and albumin-to- creatinine ratio (ACR) among NHANES participants ≥ 80 years of age.

Calendar Period 1988 – 1994

(n=1,020)

1999 – 2004 (n=995)

2005 – 2010 (n=971)

p-trend eGFR, ml/min/1.73

m

2

≥ 60 59.5 (55.4-63.6) 50.1 (46.4-53.8) 48.8 (45.2-52.3) ref 45 to 59 26.2 (23.3-29.1) 31.3 (28.0-34.6) 29.4 (26.3-32.5) 0.010

< 45 14.3 (11.6-17.0) 18.6 (15.9-21.3) 21.7 (19.0-24.4) <0.001 Albumin-to-

creatinine ratio (ACR), mg/g

< 30 69.1 (65.2-73.0) 67.0 (63.7-70.3) 69.4 (66.6-72.1) ref

≥ 30 30.9 (27.0-34.8) 33.0 (29.7-36.3) 30.6 (27.9-33.3) 0.930 Numbers in table are percentage (95% confidence interval).

ACR – albumin-to-creatinine ratio; eGFR – estimated glomerular filtration rate

 

   

(2)

MAJ14-171 Bowling et al

Supplemental Materials  

Table S2. Number of US adults ≥ 80 years of age with reduced eGFR and

elevated albumin-to- creatinine ratio (ACR)

.

Calendar Period 1988 – 1994

(n=1,020)

1999 – 2004 (n=995)

2005 – 2010 (n=971)

2030 2050 eGFR, ml/min/1.73

m2

< 60 2.34 (1.79 – 2.89)

3.55 (2.96 – 4.14)

4.58 (3.87 – 5.28)

9.94 (9.26 – 10.63)

15.81 (14.72 – 16.90) 45 to 59 1.51 (1.16 –

1.87)

2.23 (1.86 – 2.60)

2.64 (2.19 – 3.09)

5.72 (5.11 – 6.33)

9.10 (8.13 – 10.07)

< 45 0.83 (0.59 –

1.08)

1.32 (1.03 – 1.61)

1.95 (1.58 – 2.32)

4.22 (3.69 – 4.76)

6.71 (5.87 – 7.56) ACR ≥ 30 mg/g 1.78 ( 1.29-

2.27)

2.35 (1.93- 2.78)

2.74 (2.32- 3.16)

5.95 (5.42 – 6.49)

9.47 (8.62 – 10.32) eGFR < 45

ml/min/1.73 m2 and ACR ≥ 30 mg/g

0.39 (0.26 – 0.52)

0.60 (0.44 – 0.76)

0.85 (0.66 – 1.05)

1.85 (1.43 – 2.27)

2.95 (2.28 – 3.61) Numbers in table are number in millions (95% confidence interval).

ACR – albumin-to-creatinine ratio; eGFR – estimated glomerular filtration rate

 

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