daftar isi

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1. Daftar Isi ... 1

2. Peer review ... 2

3. Indeks jurnal ... 5

4. Home Jurnal ... 6

5. Editor ... 7

6. Table of Contents ... 8

7. Bukti Peserta Minimal 2

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LEMBAR

HASIL PENILAIAN SEJAWAT SEBIDANG ATAU PEER REVIEW KARYA ILMIAH : JURNAL ILMIAH

Judul Artikel Ilmiah : Indoleamine 2, 3-dioxygenase (IDO) levels in leprosy patients with positive serology

Nama semua penulis : Ago Harlim penulis, M. Zen Rahfiludin

Status Pengusul (coret yg tidak perlu) : Penulis Utama/ Penulis Utama & Korespondensi/ Penulis Korespondensi/

Penulis Anggota Status Jurnal:

 Nama Jurnal : Journal of Pakistan Association of Dermatologist

 Tahun terbit/Vol/No/halaman : Volume 27 / No. 2 / Hal. 131-134

 Edisi (bulan, tahun) : April – Juni 2017

 ISSN : 1560 – 9014 (Print) , 2413 – 7650 (Online)

 DOI : -

 Alamat WEB Jurnal : http://www.jpad.com.pk/index.php/jpad/article/view/1079

 Terindex di : Scopus Q4 SJR 2019 : 0,173 Kategori Publikasi (beri tanda V yang sesuai)

 Jurnal Internasional [ [ [ ] ] ]

Jurnal internasional bereputasi & memiliki impact factor Jurnal internasional bereputasi,

Jurnal Internasional

 Jurnal Nasional [√]

[ ] [ ] [ ]

Jurnal Nasional Terakreditasi

Jurnal Nasional berbahasa Inggris Terindeks CABI atau Copernicus, atau Berbahasa Inggris Terkreditasi Peringkat 3 atau 4

Jurnal Nasional berbahasa Indonesia Terakreditasi peringkat 3 atau 4 Jurnal Nasional

Hasil Penilaian Peer Review :

Komponen Yang Dinilai

Nilai Reviewer Nilai Rata-rata /Nilai Akhir

yang diperoleh Reviewer I Reviewer II

a. Kelengkapan unsur isi jurnal (10%) 1 1,5 1,25

b. Ruang lingkup dan kedalaman pembahasan (30%) 6 4,5 5,25

c. Kecukupan dan kemutahiran data/informasi dan

metodologi (30%) 6 4,5 5,25

d. Kelengkapan unsur dan kualitas penerbit (30%) 6 4,5 5,25

Total = (100%) 19 15 17

Nilai pengusul = 40% x 17 = 6,8

Reviewer 1

Prof. Dr. Sri Sumarmi, S.KM., M.Si NIP 196806251992932002

Unit kerja: FKM Universitas Airlangga

Reviewer 2

Prof. Dr. Merryana Adriani, S.KM., M.Kes NIP 195905171994032001

Unit kerja : FKM Universitas Airlangga

(3)

Lamp C….

LEMBAR

HASIL PENILAIAN SEJAWAT SEBIDANG ATAU PEER REVIEW KARYA ILMIAH: JURNAL ILMIAH

Judul Artikel Ilmiah : Indoleamine 2, 3-dioxygenase (IDO) levels in leprosy patients with positive serology

Nama semua penulis : Ago Harlim penulis, M. Zen Rahfiludin

Status Pengusul (coret yg tidak perlu) : Penulis Utama/ Penulis Utama & Korespondensi/ Penulis Korespondensi/

Penulis Anggota Status Jurnal:



Nama Jurnal : Journal of Pakistan Association of Dermatologist



Tahun terbit/Vol/No/halaman : Volume 27 / No. 2 / Hal. 131-134



Edisi (bulan, tahun) : April – Juni 2017



ISSN : 1560 – 9014 (Print) , 2413 – 7650 (Online)



DOI : -



Alamat WEB Jurnal :

http://www.jpad.com.pk/index.php/jpad/article/view/1079



Terindex di : Scopus Q4 SJR 2019 : 0,173

Kategori Publikasi (beri tanda V yang sesuai)



Jurnal Internasional [ [ [

] ] ]

Jurnal internasional bereputasi & memiliki impact factor Jurnal internasional bereputasi,

Jurnal Internasional



Jurnal Nasional [√]

[ ] [ ] [ ]

Jurnal Nasional Terakreditasi

Jurnal Nasional berbahasa Inggris Terindeks CABI atau Copernicus, atau Berbahasa Inggris Terkreditasi Peringkat 3 atau 4

Jurnal Nasional berbahasa Indonesia Terakreditasi peringkat 3 atau 4 Jurnal Nasional

Hasil Penilaian Peer Review:

No Komponen yang dinilai Nilai Maksimal Artikel

Jurnal Nasional Terakreditasi Nilai yang didapat artikel

a Kelengkapan unsur isi artikel (10 %) 2,5 1

b Ruang lingkup & kedalaman pembahasan (30 %) 7,5 6

c Kecukupan dan kemutahiran data/informasi dan

metodologi (30 %) 7,5 6

d Kelengkapan unsur dan kualitas jurnal (30%) 7,5 6

Nilai Total 25 19

Nilai yang didapat pengusul: 40% X 19 = 7,6 Catatan Penilaian artikel oleh Reviewer

a Kelengkapan unsur isi artikel Unsur artikel lengkap, telah memenuhi kaidah penulisan artikel dalam jurnal ilmiah

b Ruang lingkup & kedalaman pembahasan Artikel membahas tentang gambaran kadar indoleamin 2, 3- dioxygenase (IDO)pada penderita kusta. Pembahasan cukup baik menggunakan referensi yang relevan

c Kecukupan dan kemutahiran data/informasi dan metodologi

Data mutakhir, diperoleh dari penelitian cross sectional dengan besar sampel memadai untuk analisis statistic comparative.

d Kelengkapan unsur dan kualitas jurnal Diterbitkan pada jurnal terindex scopus Q4 SJR adalah 0,173 similarity index 17%. Artikel terindeks scopus namun editor dalam jurnal hanya berasal dari Pakistan sehingga nilai artikel turun menjadi jurnal nasional terakreditasi

Surabaya, 31 Desember 2019 Reviewer 1

Prof. Dr. Sri Sumarmi, S.KM., M.Si NIP 196806251992932002

Unit kerja: Fakultas Kesehatan Masyarakat Universitas Airlangga

(4)

Lamp C...

LEMBAR

HASIL PENILAIAN SEJAWAT SEBIDANG ATAU PEER REVIEW KARYA ILMIAH: JURNAL ILMIAH

Judul Artikel Ilmiah : Indoleamine 2, 3-dioxygenase (IDO) levels in leprosy patients with positive serology

Nama semua penulis : Ago Harlim penulis, M. Zen Rahfiludin

Status Pengusul (coret yg tidak perlu) : Penulis Utama/ Penulis Utama & Korespondensi/ Penulis Korespondensi/

Penulis Anggota Status Jurnal:



Nama Jurnal : Journal of Pakistan Association of Dermatologist



Tahun terbit/Vol/No/halaman : Volume 27 / No. 2 / Hal. 131-134



Edisi (bulan, tahun) : April – Juni 2017



ISSN : 1560 – 9014 (Print) , 2413 – 7650 (Online)



DOI : -



Alamat WEB Jurnal :

http://www.jpad.com.pk/index.php/jpad/article/view/1079



Terindex di : Scopus Q4 SJR 2019 : 0,173

Kategori Publikasi (beri tanda V yang sesuai)



Jurnal Internasional [ [ [

] ] ]

Jurnal internasional bereputasi & memiliki impact factor Jurnal internasional bereputasi,

Jurnal Internasional



Jurnal Nasional [√]

[ ] [ ] [ ]

Jurnal Nasional Terakreditasi

Jurnal Nasional berbahasa Inggris Terindeks CABI atau Copernicus, atau Berbahasa Inggris Terkreditasi Peringkat 3 atau 4

Jurnal Nasional berbahasa Indonesia Terakreditasi peringkat 3 atau 4 Jurnal Nasional

Hasil Penilaian Peer Review:

No Komponen yang dinilai Nilai Maksimal Artikel

Jurnal Nasional Terakreditasi Nilai yang didapat artikel

a Kelengkapan unsur isi artikel (10 %) 2,5 1,5

b Ruang lingkup & kedalaman pembahasan (30 %) 7,5 4,5

c Kecukupan dan kemutahiran data/informasi dan

metodologi (30 %) 7,5 4,5

d Kelengkapan unsur dan kualitas jurnal (30%) 7,5 4,5

Nilai Total 25 15

Nilai yang didapat pengusul: 40% x 15 = 6 Catatan Penilaian artikel oleh Reviewer

a Kelengkapan unsur isi artikel Isi jurnal telah sesuai dengan “Guide for Author” substansi bidang ilmu telah sesuai dengan bidang ilmu pengusul “Ilmu Gizi Kesehatan Masyarakat”. Telah ada benang merah dalam struktur penulisannya.

b Ruang lingkup & kedalaman

pembahasan Substansi artikel telah sesuai dengan ruang lingkup “Journal of Pakistan Association of Dermatologist” kedalaman pembahasan telah melibatkan semua rujukan (15 rujukan) dalam analisis yang tertuang dalam pembahasan.

c Kecukupan dan kemutahiran data/informasi dan metodologi

Data hasil penelitian telah dianalisis dengan metodologi yang sesuai sehingga dapat ditarik kesimpulan yang dapat dipertanggung jawabkan.

d Kelengkapan unsur dan kualitas jurnal Journal of Pakistan Association of Dermatologist merupakan jurnal internasional bereputasi dengan indeks scimagojr 0,18 Best Quartile (Q4) dengan cite score 0,11 (43 citatios >317 documents).

Editorial team hanya berasal dari 1 negara yaitu Pakistan sehinnga nilai menjadi jurnal nasional terakreditasi

Surabaya 3 Januari 2020 Reviewer 2

Prof. Dr. Merryana Adriani, S.KM., M.Kes NIP 195905171994032001

Unit kerja : Fakultas Kesehatan Masyarakat Universitas Airlangga

(5)

7 of 15

Indoleamine 2, 3-dioxygenase (IDO) level in leprosy patients with positive serology

^(Article)

,

Faculty of Medicine, The Christian University of Indonesia, Jl. Mayjen Sutoyo., Cawang, Jakarta Timur, 50275, Indonesia

Faculty of Public Health, Diponegoro University, Indonesia Jl. Prof. Soedarto, Sh, Tembalang, Semarang, 50239, Indonesia

Abstract

Background Seropositive leprosy individuals have a tendency to experience a change into leprosy lepromatous type.

Previous studies have demonstrated that the activity of indoleamine 2, 3-dioxygenase (IDO) in patients with lepromatous type leprosy is higher than those with tuberculoid type leprosy. However, no study has been available showing how IDO level can be correlated to seropositive subjects. Methods Our observational cross-sectional study was conducted in Brebes, Central Java, Indonesia. Leprosy seropositivity was determined by measuring the level of anti-phenolic glycolipid-1 IgM and IDO level using ELISA. Results Result of The IDO level in seropositive leprosy subjects was higher compared to those who were seronegative (p = 0.048). Conclusion In the early stage of leprosy infection, a high level of IDO level can already be found; therefore, it can aﬀect immune response and ultimately aﬀecting further course of the disease.

SciVal Topic Prominence

Topic:

Prominence percentile: 91.859

Author keywords

3-dioxygenase Anti-phenolic glycolipid-1 IgM Indoleamine 2 Seropositive leprosy

Indexed keywords

EMTREE drug terms: immunoglobulin M antibody indoleamine 2,3 dioxygenase phenolic glycolipid I

EMTREE medical terms:

adult Article clinical article controlled study cross-sectional study enzyme analysis enzyme linked immunosorbent assay female human immune response Indonesia leprosy lipid analysis male observational study outcome assessment serology

Chemicals and CAS Registry Numbers:

indoleamine 2,3 dioxygenase

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Open Access Journal of Pakistan Association of Dermatologists

Volume 27, Issue 2, 2017, Pages 131-134

Harlim, A.^a Rahﬁludin, M.Z.^b  

a b

 View references (15)



Leprosy | Mycobacterium Leprae | Notiﬁable Disease

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ISSN: 15609014 CODEN: JPADF Source Type: Journal Original language: English

Document Type: Article

Publisher: Pakistan Association of Dermatologists

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Journal of Pakistan Association of Dermatology

The Journal of Pakistan Association of Dermatologists is the official journal the Pakistan. It is published quarterly, four issues per volume and one volume per year (ISSN 1560-9014). The journal is recognized by Pakistan Medical and Dental Council and is indexed in:

1. College of Physicians and Surgeons Pakistan MEDLIP 2. Ulrich’s International Periodical Directory, USA 3. ExtraMED, London

4. EMBASE/Excerpta Medica, The Netherlands 5. Index Medicus, WHO Alexandria, Egypt.

6. Pak Medinet, Islamabad

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Dr. Zahida Rani, Professor of Dermatology Khawaja Muhammad Safdar Medical College, Sialkot Mobile: +92 3004421244, Pakistan

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Home > Archives > Vol 27, No 2 (2017)

Vol 27, No 2 (2017)

April - June

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Journal of Pakistan Association of Dermatologists. 2017;27 (2):131-134.

131 Address for correspondence

Dr. M. Zen Rahfiludin Faculty of Public Health,

Universitas of Diponegoro, Jl. Prof Soedarto Sh, Tembalang. Semarang. Indonesia

Email: [email protected]

Original Article

Indoleamine 2, 3-dioxygenase (IDO) levels in leprosy patients with positive serology

Introduction

Leprosy still remains a major public health problem in Indonesia since the incidence of leprosy is relatively high.

¹

It is possibly due to contact with seropositive leprosy patients that have been turning into manifest leprosy.

Measuring the level of anti-phenolic glycolipid- 1 immunoglobulin M (PGL-1 IgM) is one of the methods to detect seropositive leprosy subjects.

^2,3

The level of such cellular immune response will determine leprosy spectrum. The

cellular immunity in leprosy tuberculoid type is still good, on the contrary, there is decreased cellular immunity in leprosy lepromatous type.

⁴

Individuals with seropositive leprosy contact (IgM anti-PGL-1 level more than 600 unit/ml), have a tendency to experience a change into leprosy lepromatous type.

Previous studies have demonstrated that leprosy patients with lepromatous type have a higher activity of indoleamine 2, 3-dioxygenase (IDO) compared to those with tuberculoid type. The role of IDO levels in leprosy has been studied

and an increased number of

macrophages/dendritic cells (DC–lineage IDO+

cells were found in lepromatous (LL) compared to tuberculoid (BT) and reversal reaction (RR) patients. LL lesions were characterized by

Ago Harlim, M. Zen Rahfiludin*

Faculty of Medicine, The Christian University of Indonesia, Jl. Mayjen Sutoyo. Cawang . Jakarta Timur (50275). Indonesia

* Faculty of Public Health, Diponegoro University, Indonesia Jl. Prof. Soedarto, Sh, Tembalang, Semarang (50239). Indonesia

Abstract

Background Seropositive leprosy individuals have a tendency to experience a change into leprosy lepromatous type. Previous studies have demonstrated that the activity of indoleamine 2, 3- dioxygenase (IDO) in patients with lepromatous type leprosy is higher than those with tuberculoid type leprosy. However, no study has been available showing how IDO level can be correlated to seropositive subjects.

Methods Our observational cross-sectional study was conducted in Brebes, Central Java, Indonesia.

Leprosy seropositivity was determined by measuring the level of anti-phenolic glycolipid-1 IgM and IDO level using ELISA.

Results Result of The IDO level in seropositive leprosy subjects was higher compared to those who were seronegative (p = 0.048).

Conclusion In the early stage of leprosy infection, a high level of IDO level can already be found;

therefore, it can affect immune response and ultimately affecting further course of the disease . Key words

Seropositive leprosy, indoleamine 2, 3-dioxygenase, anti-phenolic glycolipid-1 IgM.

(11)

Journal of Pakistan Association of Dermatologists. 2017;27 (2):102-109 .

Ms Sumaira Sajjad

Institute of Biomedical and Genetic Engineering Mauve Area G-9/1 Islamabad Pakistan,

Email: [email protected]

Original Article

VDR polymorphisms ApaI (rs7975232), TaqI (rs731236) and FokI (rs2228570) in Pakistani vitiligo patients and controls

Introduction

Vitiligo is a depigmentation skin disorder caused by destruction of melanocytes.

¹

The prevalence of the disease is around 1% in the United States and Europe, while in rest of the world its ranges from less than 0.1% to greater than 8%. Gujrat India tops the list in having prevalence of about

8.8%.

²

According to US Census Bureau, International Data Base 2004 estimated prevalence in Pakistan is 0.1%. The etiopathogenesis of vitiligo has not been fully elucidated and several theories have been proposed. Among those, the autoimmune hypothesis is currently the most accepted one.

The presence of T cell-mediated melanocyte destruction and the association of vitiligo with autoimmune conditions, such as Hashimoto’s and Addison’s diseases, pernicious anemia, type 1 diabetes and systemic lupus erythematosus, are

Sumaira Sajjad, Saeeda Munir, Simeen-Ber-Rahman*, Nusrat Saba, Sadia Rehman

Institute of Biomedical and Genetic Engineering Islamabad, G9/1 Mauve Area, 44000, Pakistan

*Siemens’ Skin and laser center Peshawar road Rawalpindi

Abstract

^Objective To understand the role of three single nucleotide polymorphisms (SNP) of vitamin D receptor (VDR) gene rs7975232, rs731236 and rs2228570 in Pakistani vitiligo patients and ethnically matched controls.

Methods 196 vitiligo patients and 262 controls were included in this study. Genomic DNA was extracted and polymerase chain reaction, restriction length polymorphism (PCR-RFLP) was done.

Results Genotype CA (rs7975232) was found to be associated with susceptibility (Odd ratio=1.46, 95% CI=1.01-2.13, p=0.046) and TT genotype (rs731236) with protection (Odd ratio=0.48, 95%

CI=0.25-0.92, p=0.003) to vitiligo. TT genotype for rs731236 was significantly high in controls and absent in undetermined/unclassified group of patients. Vitiligo patients and controls were also compared on the basis of gender. Genotype CA (OR=2.12, 95% CI=1.18-3.79, p=0.013) and CC (OR =0.21 95% CI=0.06-0.73, p=0.007) for rs7975232 were significantly high in male patients and controls, respectively. For rs2228570 CC genotype was significantly high in controls (OR=0.52, 95% CI=0.2-0.97), p=0.04) while TC genotype showed significant difference between patient and controls (OR=1.93, 95% CI=1.02-3.6), p=0.05). In combined effect haplotype A-T-C was found significantly high in controls as compared with the patients (Odd ratio=0.57, 95% CI=0.34-0.97, p=0.04).

Conclusion VDR polymorphisms may be involved in etiology of vitiligo and future studies should be design to screen large sample size for more VDR polymorphism to get more precise picture.

Key words

Vitamin D receptor, vitiligo, polymorphism, polymerase chain reaction, restriction length polymorphism.

(12)

Journal of Pakistan Association of Dermatologists. 2017;27 (2):120-123.

Dr. Shashikant Malkud, Assistant Professor Department of Dermatology, Venereology &

Leprosy,

MNR Medical College & Hospital Sangareddy - 502001, Telangana, India Email: [email protected]

Original Article

Childhood herpes zoster: a study from tertiary center

Introduction

Herpes zoster (HZ) results from reactivation of a latent infection by varicella-zoster virus (VZV).

VZV is present in dormant form in sensory ganglia after varicella infection. It usually occurs due to decline in specific cell-mediated immunity against VZV. It is most often seen in old age and immunocompromised patients.

However, it may also occur in children.

¹

During the past decades, HZ has been identified

with increasing frequency in apparently immunocompetent children.

²

HZ in immunocompetent children typically has a benign course with mild constitutional symptoms.

¹

Till today only few studies have been conducted in India on childhood herpes zoster.

Methods

It was a hospital-based cross-sectional study conducted in department of Dermatology, Venereology and Leprosy of Employee State Insurance Corporation (ESIC) hospital, Kalaburagi, Karnataka. The study was conducted between the period of February 2013 to February 2016. Study approval was taken from institutional ethical committee. Thirty

Shashikant Malkud, Veeresh Dyavannanavar*

Department of Dermatology, Venereology & Leprosy, MNR Medical College & Hospital, Sangareddy-502001, Telangana, India

* Department of Dermatology, Venereology & Leprosy, Gadag Institute of Medical Sciences, Gadag-582103, Karnataka, India

Abstract

Objective To document clinical features of herpes zoster in children.

Methods Thirty children with herpes zoster were included in the study. Detailed history and thorough clinical examination was done in all patients. Tzanck smear was prepared from the floor of vesicle. Blood was collected for complete blood count, human immunodeficiency virus (HIV) serology, anti-VZV IgM and IgG antibodies. After parental consent skin biopsy was taken and sent for histopathology.

Results Of 30 children, 18 (60%) were boys and 12 (40%) were girls. Most of the patients were immunocompetent and only 3 patients were immunocompromised. Past history of varicella was noted in 13 (43.3%) patients. Only 5 (16.6%) patients had received VZV immunization. Thoracic dermatomes were more commonly involved in 17 (56.7%) patients followed by lumbar in 6 (20%), cervical in 5 (16.7%), cranial in 1 (3.3%) and sacral in 1 (3.3%) patient. Most of the children were asymptomatic and only 4 (13.3%) patients had noticed zoster associated pain.

Conclusion Most of the children with herpes zoster were immunocompetent. Thoracic dermatomes were more frequently involved. The disease is generally mild with fewer complications.

Key words

Children, immunocompetent, herpes zoster.