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30-Day Postoperative Complication Rates in Cervical and Lumbar Spine Surgeries

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Appendix 1. Number and percent of patients who developed complications during the 30 days following anterior cervical decompression and fusion procedures, stratified by number of levels.

1 level (N=6,914) 2 or more levels (N=5,153)

Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 24 0.35% 0.21-0.49% 40 0.78% 0.54-1.02% <0.001 Pneumonia 22 0.32% 0.19-0.45% 36 0.70% 0.47-0.93% 0.002 Surgical site infection 34 0.49% 0.33-0.66% 15 0.29% 0.14-0.44% 0.087 Urinary tract infection 23 0.33% 0.20-0.47% 20 0.39% 0.22-0.56% 0.610

Sepsis 13 0.19% 0.09-0.29% 15 0.29% 0.14-0.44% 0.246

Deep vein thrombosis 15 0.22% 0.11-0.33% 9 0.17% 0.06-0.29% 0.516 Myocardial infarction 7 0.10% 0.03-0.18% 9 0.17% 0.06-0.29% 0.271 Pulmonary embolism 6 0.09% 0.02-0.16% 7 0.14% 0.04-0.24% 0.418 CI = confidence interval.

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Appendix 2. Number and percent of patients who developed complications during the 30 days following posterior lumbar fusion procedures, stratified by number of levels.

1 level (N=6,867) 2 or more levels (N=4,940)

Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 756 11.02% 10.28-11.76% 1,304 26.36% 25.14-27.59% <0.001 Urinary tract infection 95 1.38% 1.11-1.66% 113 2.28% 1.87-2.70% <0.001 Surgical site infection 109 1.59% 1.29-1.88% 99 2.00% 1.61-2.39% 0.089

Sepsis 52 0.76% 0.55-0.96% 49 0.99% 0.71-1.27% 0.171

Pneumonia 40 0.58% 0.40-0.76% 46 0.93% 0.66-1.20% 0.028

Deep vein thrombosis 31 0.45% 0.29-0.61% 51 1.03% 0.75-1.31% <0.001 Pulmonary embolism 22 0.32% 0.19-0.45% 36 0.73% 0.49-0.96% 0.002 Myocardial infarction 22 0.32% 0.19-0.45% 15 0.30% 0.15-0.49% 0.873 CI = confidence interval.

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Appendix 3. Number and percent of patients who developed complications during the 30 days following posterior lumbar fusion procedures, stratified by use of an interbody device.

No interbody (N=6,713) Interbody (N=5,094)

Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 1,291 19.23% 18.29-20.17% 769 15.1% 14.11-16.08% <0.001 Urinary tract infection 120 1.79% 1.47-2.10% 88 1.73% 1.37-2.09% 0.803 Surgical site infection 137 2.04% 1.70-2.38% 71 1.39% 1.07-1.72% 0.008

Sepsis 67 1.00% 0.76-1.24% 34 0.67% 0.44-0.89% 0.054

Pneumonia 52 0.77% 0.56-0.98% 34 0.67% 0.44-0.89% 0.497

Deep vein thrombosis 53 0.79% 0.58-1.00% 29 0.57% 0.36-0.78% 0.153 Pulmonary embolism 32 0.48% 0.31-0.64% 26 0.51% 0.31-0.71% 0.795 Myocardial infarction 25 0.37% 0.23-0.52% 12 0.24% 0.10-0.37% 0.187 CI = confidence interval.

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row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Myocardial Infarction Anemia Requiring Transfusion

Sepsis

Urinary Tract Infection Deep Vein Thrombosis Surgical Site Infection Pneumonia

Pulmonary Embolism

Days After Surgery

Summary Statistics for Timing of Complications Following Anterior Cervical Decompression and Fusion, by Levels

Myocardial Infarction Anemia Requiring Transfusion

Pulmonary Embolism

Urinary Tract Infection Sepsis Surgical Site Infection Pneumonia

Deep Vein Thrombosis

Days After Surgery

1 Level

Days After Surgery

2 or More Levels

Appendix 4

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

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row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Myocardial Infarction Anemia Requiring Transfusion

Pulmonary Embolism

Surgical Site Infection Sepsis Deep Vein Thrombosis Pneumonia

Urinary Tract Infection

Days After Surgery

Summary Statistics for Timing of Complications Following Posterior Lumbar Fusion, by Levels

Myocardial Infarction Anemia Requiring Transfusion

Pulmonary Embolism

Surgical Site Infection Deep Vein Thrombosis Sepsis Pneumonia

Urinary Tract Infection

Days After Surgery

1 Level

Days After Surgery

2 or More Levels

Appendix 5

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

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row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Myocardial Infarction Anemia Requiring Transfusion

Pulmonary Embolism

Surgical Site Infection Sepsis Urinary Tract Infection Pneumonia

Deep Vein Thrombosis

Days After Surgery

Summary Statistics for Timing of Complications Following Posterior Lumbar Fusion, by Use of Interbody

Myocardial Infarction Anemia Requiring Transfusion

Pulmonary Embolism

Surgical Site Infection Sepsis Deep Vein Thrombosis Pneumonia

Urinary Tract Infection

Days After Surgery

No interbody

Days After Surgery

Interbody

Appendix 6

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

Median Day Interquartile Range Middle 80%

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

row

0 5 10 15 20 25 30

Percent of Patients with adverse ratio (%)

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