Appendix 1. Number and percent of patients who developed complications during the 30 days following anterior cervical decompression and fusion procedures, stratified by number of levels.
1 level (N=6,914) 2 or more levels (N=5,153)
Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 24 0.35% 0.21-0.49% 40 0.78% 0.54-1.02% <0.001 Pneumonia 22 0.32% 0.19-0.45% 36 0.70% 0.47-0.93% 0.002 Surgical site infection 34 0.49% 0.33-0.66% 15 0.29% 0.14-0.44% 0.087 Urinary tract infection 23 0.33% 0.20-0.47% 20 0.39% 0.22-0.56% 0.610
Sepsis 13 0.19% 0.09-0.29% 15 0.29% 0.14-0.44% 0.246
Deep vein thrombosis 15 0.22% 0.11-0.33% 9 0.17% 0.06-0.29% 0.516 Myocardial infarction 7 0.10% 0.03-0.18% 9 0.17% 0.06-0.29% 0.271 Pulmonary embolism 6 0.09% 0.02-0.16% 7 0.14% 0.04-0.24% 0.418 CI = confidence interval.
Appendix 2. Number and percent of patients who developed complications during the 30 days following posterior lumbar fusion procedures, stratified by number of levels.
1 level (N=6,867) 2 or more levels (N=4,940)
Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 756 11.02% 10.28-11.76% 1,304 26.36% 25.14-27.59% <0.001 Urinary tract infection 95 1.38% 1.11-1.66% 113 2.28% 1.87-2.70% <0.001 Surgical site infection 109 1.59% 1.29-1.88% 99 2.00% 1.61-2.39% 0.089
Sepsis 52 0.76% 0.55-0.96% 49 0.99% 0.71-1.27% 0.171
Pneumonia 40 0.58% 0.40-0.76% 46 0.93% 0.66-1.20% 0.028
Deep vein thrombosis 31 0.45% 0.29-0.61% 51 1.03% 0.75-1.31% <0.001 Pulmonary embolism 22 0.32% 0.19-0.45% 36 0.73% 0.49-0.96% 0.002 Myocardial infarction 22 0.32% 0.19-0.45% 15 0.30% 0.15-0.49% 0.873 CI = confidence interval.
Appendix 3. Number and percent of patients who developed complications during the 30 days following posterior lumbar fusion procedures, stratified by use of an interbody device.
No interbody (N=6,713) Interbody (N=5,094)
Complication No. Percent 95% CI No. Percent 95% CI P-value Anemia requiring transfusion 1,291 19.23% 18.29-20.17% 769 15.1% 14.11-16.08% <0.001 Urinary tract infection 120 1.79% 1.47-2.10% 88 1.73% 1.37-2.09% 0.803 Surgical site infection 137 2.04% 1.70-2.38% 71 1.39% 1.07-1.72% 0.008
Sepsis 67 1.00% 0.76-1.24% 34 0.67% 0.44-0.89% 0.054
Pneumonia 52 0.77% 0.56-0.98% 34 0.67% 0.44-0.89% 0.497
Deep vein thrombosis 53 0.79% 0.58-1.00% 29 0.57% 0.36-0.78% 0.153 Pulmonary embolism 32 0.48% 0.31-0.64% 26 0.51% 0.31-0.71% 0.795 Myocardial infarction 25 0.37% 0.23-0.52% 12 0.24% 0.10-0.37% 0.187 CI = confidence interval.
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Myocardial Infarction Anemia Requiring Transfusion
Sepsis
Urinary Tract Infection Deep Vein Thrombosis Surgical Site Infection Pneumonia
Pulmonary Embolism
Days After Surgery
Summary Statistics for Timing of Complications Following Anterior Cervical Decompression and Fusion, by Levels
Myocardial Infarction Anemia Requiring Transfusion
Pulmonary Embolism
Urinary Tract Infection Sepsis Surgical Site Infection Pneumonia
Deep Vein Thrombosis
Days After Surgery
1 Level
Days After Surgery
2 or More Levels
Appendix 4
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Myocardial Infarction Anemia Requiring Transfusion
Pulmonary Embolism
Surgical Site Infection Sepsis Deep Vein Thrombosis Pneumonia
Urinary Tract Infection
Days After Surgery
Summary Statistics for Timing of Complications Following Posterior Lumbar Fusion, by Levels
Myocardial Infarction Anemia Requiring Transfusion
Pulmonary Embolism
Surgical Site Infection Deep Vein Thrombosis Sepsis Pneumonia
Urinary Tract Infection
Days After Surgery
1 Level
Days After Surgery
2 or More Levels
Appendix 5
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Myocardial Infarction Anemia Requiring Transfusion
Pulmonary Embolism
Surgical Site Infection Sepsis Urinary Tract Infection Pneumonia
Deep Vein Thrombosis
Days After Surgery
Summary Statistics for Timing of Complications Following Posterior Lumbar Fusion, by Use of Interbody
Myocardial Infarction Anemia Requiring Transfusion
Pulmonary Embolism
Surgical Site Infection Sepsis Deep Vein Thrombosis Pneumonia
Urinary Tract Infection
Days After Surgery
No interbody
Days After Surgery
Interbody
Appendix 6
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
Median Day Interquartile Range Middle 80%
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)
row
0 5 10 15 20 25 30
Percent of Patients with adverse ratio (%)