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OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

F

LORISSI ET AL

.

E

XTERNAL

V

ALIDATION OF THE

P

ATIENT

A

CCEPTABLE

S

YMPTOM

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TATE FOR THE

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URO

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-5 D

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1 Y

EAR

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FTER

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IP

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RTHROPLASTY

http://dx.doi.org/10.2106/JBJS.20.00184 Page 1

The following content was supplied by the authors as supporting material and has not been copy-edited or verified by JBJS.

Appendix Table 1. Spearman’s rank correlation of the EQ-5D and the satisfaction NRS question*.

Procedure Coefficient p-value

THA -0.41 <0.001

THA: Total hip arthroplasty

NRS: Numerical Rating Scale

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C

OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

F

LORISSI ET AL

.

E

XTERNAL

V

ALIDATION OF THE

P

ATIENT

A

CCEPTABLE

S

YMPTOM

S

TATE FOR THE

E

URO

Q

OL

-5 D

IMENSION

1 Y

EAR

A

FTER

T

OTAL

H

IP

A

RTHROPLASTY

http://dx.doi.org/10.2106/JBJS.20.00184 Page 2

Appendix Table 2. Areas under the Receiver Operating Characteristic curve for pre-established EQ-5D PASS thresholds externally validated on data from an Institutional registry. EQ-5D

indices in the validation cohort were derived using either the UK value set or the same value set as the predefined PASS. 95% confidence intervals can be seen in parentheses.

Value Set 0.92 THA PASS (Naal et al,

2015)*

0.82 THA PASS (Paulsen et al.

2014)**

Matching Value Set 0.731 (0.706-0.757) 0.787 (0.763-0.810)

UK Value Set 0.731 (0.706-0.757) 0.777 (0.753-0.801)

* Unweighted scoring method (Prieto and Sacristan, 2004

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)

** Danish value set (Paulsen et al, 2014

7

) THA: Total hip arthroplasty

PASS: Patient Acceptable Symptom State

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C

OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

F

LORISSI ET AL

.

E

XTERNAL

V

ALIDATION OF THE

P

ATIENT

A

CCEPTABLE

S

YMPTOM

S

TATE FOR THE

E

URO

Q

OL

-5 D

IMENSION

1 Y

EAR

A

FTER

T

OTAL

H

IP

A

RTHROPLASTY

http://dx.doi.org/10.2106/JBJS.20.00184 Page 3

Appendix Figure 1. Histogram of numerical rating scale (NRS) satisfaction responses at one year

following total hip arthroplasty. Lower scores indicate greater satisfaction. The dichotomization

threshold of 2.5 was set on the basis of precedent in literature

12

as well as the shape of the

distribution of responses.

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C

OPYRIGHT

©

BY

T

HE

J

OURNAL OF

B

ONE AND

J

OINT

S

URGERY

, I

NCORPORATED

F

LORISSI ET AL

.

E

XTERNAL

V

ALIDATION OF THE

P

ATIENT

A

CCEPTABLE

S

YMPTOM

S

TATE FOR THE

E

URO

Q

OL

-5 D

IMENSION

1 Y

EAR

A

FTER

T

OTAL

H

IP

A

RTHROPLASTY

http://dx.doi.org/10.2106/JBJS.20.00184 Page 4

Appendix Figure 2. Box Plot of EQ-5D Index scores for satisfied and non-satisfied patients in

the external validation cohort one year following total hip arthroplasty. Higher EQ-5D scores

indicate greater self-reported health-related quality of life.

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